Published English-language literature
PBM research statistics
The PBM Database contains 10,028 English-language publications on photobiomodulation. The records cover 277 conditions across 24 medical specialties, 65 countries and three research-model groups.
Source: PBM Database statistics and the WALT 2026 presentation. Publication and country totals are for 2026.
Publication counts over time
Cumulative publications
The database count rose from 166 publications in 1990 to 10,028 in 2026.
Photobiomodulation research over time
Cumulative publications represented in the database at selected years.
Countries represented
Publication counts by country
Counts for the 30 largest named groups are shown below. Earlier Brazil, United States, China and Iran totals are retained; the remaining balance is grouped as other countries.
The 30 named groups total 9,045 publications; other countries account for 983, bringing the chart to 10,028.
Study models
Publications by study model
The database groups publications as human research, animal experiments or in-vitro research.
Human studies
clinical and human research
Animal experiments
preclinical research
17 additional species
Sheep (9); zebrafish, toad and cat (5 each); tree shrew (4); bumblebee and planarian (3 each); frog / tadpole, daphnia, earthworm and nematode (2 each); parakeet, ray, gerbil, honeybee, medaka and catfish (1 each).
In-vitro studies
cellular and laboratory research
The control-group counts are database categories and may overlap; they are not intended to sum to a unique-study total.
Review literature
Reviews in the database
Meta-analyses are included within the systematic-review count.
Research publication venues
PBM research appears in established journals
A working list from the PBM Database records hundreds of PBM papers in journals with impact factors of 3.0 or higher. This shows that PBM is part of mainstream scholarly publishing—not that every claim or treatment is proven.
The supplied journal list is incomplete and includes different publication types. Journal impact factor is a journal-level metric, not a measure of the quality or reliability of an individual study.
Examples across different kinds of research
- Randomized clinical trial of PBM for Bothrops atrox snakebiteJAMA Internal Medicine · 2024 · human clinical research↗
- Noninvasive low-level laser therapy for thrombocytopeniaScience Translational Medicine · 2016 · mouse research↗
- Randomized red-light trial for myopiaJAMA Ophthalmology · 2024 · human clinical research↗
- Low-level laser therapy for neck pain: systematic review and meta-analysisThe Lancet · 2009 · systematic review and meta-analysis↗
- Low-power laser for oral mucositis after bone marrow transplantation: randomized trialBlood · 2007 · human randomized trial↗
- Low-intensity laser therapy for painful diabetic neuropathy: controlled trialDiabetes Care · 2004 · sham-controlled randomized trial↗
- Photobiomodulation for methanol-induced retinal toxicityProceedings of the National Academy of Sciences · 2003 · rat model↗
- Low-energy laser irradiation after myocardial infarctionCirculation · 2001 · rat and dog models↗
- Transcranial low-level light therapy after moderate traumatic brain injuryJAMA Network Open · 2020 · randomized human trial↗
- Microglia modulation with 1070-nm light in an Alzheimer’s disease mouse modelLight: Science & Applications · 2021 · animal research↗
- Wearable NIR OLED phototherapy platform for hair-loss researchNature Communications · 2026 · device and cell research↗
- Photobiomodulation for dry age-related macular degeneration: 12-month trialBritish Journal of Ophthalmology · 2026 · multicentre clinical trial↗
- Arterial-wall photoremodeling after angioplastyJournal of the American College of Cardiology · 1998 · atherosclerotic rabbit model↗
- Near-infrared light in a monkey model of Parkinson diseaseAnnals of Neurology · 2016 · monkey model↗
- Laser therapy for activated Achilles tendinitis: placebo-controlled trialBritish Journal of Sports Medicine · 2006 · human randomized trial↗
- Laser therapy for postmastectomy lymphedema: placebo-controlled trialCancer · 2003 · human randomized trial↗