:root {
  --navy: #2a2422;
  --ink: #403936;
  --muted: #756b67;
  --paper: #fcfbf9;
  --surface: #ffffff;
  --surface-soft: #f7f0ec;
  --line: #e7ddd6;
  --blue: #c35a52;
  --teal: #289783;
  --purple: #7a62a9;
  --gold: #bf892e;
  --coral: #d36f79;
  --shadow: 0 22px 60px rgba(70, 43, 35, .11);
  --radius: 18px;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; }
body {
  margin: 0;
  color: var(--ink);
  background: var(--paper);
  font-family: Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
  font-size: 16px;
  line-height: 1.6;
}
a { color: inherit; }
img { max-width: 100%; }
.container { width: min(1180px, calc(100% - 42px)); margin: 0 auto; }
.site-header {
  position: sticky;
  top: 0;
  z-index: 10;
  border-bottom: 1px solid rgba(231, 221, 214, .9);
  background: rgba(252, 251, 249, .94);
  backdrop-filter: blur(16px);
}
.header-inner { display: flex; align-items: center; justify-content: space-between; min-height: 76px; gap: 24px; }
.brand { display: inline-flex; align-items: center; gap: 11px; color: var(--navy); text-decoration: none; }
.brand-mark {
  display: grid;
  place-items: center;
  width: 37px;
  height: 37px;
  overflow: hidden;
  border-radius: 12px;
  color: white;
  background: linear-gradient(145deg, var(--blue), #e19a55);
}
.brand-mark img { display: block; width: 27px; height: 27px; }
.brand-text { font-size: 1.02rem; font-weight: 760; letter-spacing: -.02em; }
.brand-text span { color: var(--blue); }
.site-nav { display: flex; align-items: center; gap: 24px; }
.site-nav a { color: var(--muted); font-size: .88rem; font-weight: 650; text-decoration: none; }
.site-nav a:hover, .site-nav a:focus-visible, .site-nav a[aria-current="page"] { color: var(--navy); }
.nav-toggle { display: none; border: 1px solid var(--line); border-radius: 9px; padding: 7px 9px; color: var(--navy); background: var(--surface); font: inherit; font-size: .82rem; font-weight: 700; }
.eyebrow { margin: 0 0 16px; color: var(--blue); font-size: .74rem; font-weight: 800; letter-spacing: .15em; text-transform: uppercase; }
.hero { padding: 95px 0 88px; }
.hero-grid { display: grid; grid-template-columns: minmax(0, 1.03fr) minmax(360px, .97fr); gap: 74px; align-items: center; }
h1, h2, h3 { margin: 0; color: var(--navy); letter-spacing: -.045em; }
h1 { max-width: 770px; font-size: clamp(3rem, 7vw, 5.8rem); line-height: .99; }
h2 { font-size: clamp(2rem, 4.4vw, 3.7rem); line-height: 1.05; }
h3 { font-size: 1.25rem; line-height: 1.16; }
.hero-copy { max-width: 650px; color: var(--muted); font-size: 1.14rem; }
.hero-copy p { margin: 24px 0 0; }
.actions { display: flex; flex-wrap: wrap; gap: 12px; margin-top: 31px; }
.button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  min-height: 46px;
  padding: 0 18px;
  border: 1px solid var(--blue);
  border-radius: 10px;
  color: #fff;
  background: var(--blue);
  font-size: .88rem;
  font-weight: 750;
  text-decoration: none;
  transition: transform .18s ease, background .18s ease, color .18s ease;
}
.button:hover, .button:focus-visible { color: #fff; background: var(--navy); transform: translateY(-2px); }
.button.secondary { color: var(--navy); border-color: var(--navy); background: transparent; }
.button.secondary:hover, .button.secondary:focus-visible { color: var(--navy); background: var(--surface); }
.button.small { min-height: 38px; padding: 0 13px; font-size: .8rem; }
.atlas-card { padding: 24px; border: 1px solid var(--line); border-radius: 22px; background: var(--surface); box-shadow: var(--shadow); }
.atlas-top { display: flex; justify-content: space-between; align-items: baseline; gap: 18px; padding-bottom: 20px; border-bottom: 1px solid var(--line); }
.atlas-top strong { font-size: 1.05rem; }
.atlas-top span { color: var(--muted); font-size: .76rem; }
.legend { display: flex; flex-wrap: wrap; gap: 7px 14px; margin: 17px 0 22px; color: var(--muted); font-size: .74rem; }
.legend span { display: inline-flex; align-items: center; gap: 6px; }
.dot { width: 8px; height: 8px; border-radius: 50%; background: var(--blue); }
.dot.teal { background: var(--teal); }
.dot.purple { background: var(--purple); }
.atlas-list { display: grid; gap: 10px; }
.atlas-row { display: grid; grid-template-columns: 9px 1fr auto; gap: 10px; align-items: center; padding: 10px 11px; border-radius: 9px; background: var(--surface-soft); }
.atlas-row i { display: block; width: 9px; height: 32px; border-radius: 4px; background: var(--blue); }
.atlas-row:nth-child(2) i { background: var(--teal); }
.atlas-row:nth-child(3) i { background: var(--purple); }
.atlas-row:nth-child(4) i { background: var(--gold); }
.atlas-row:nth-child(5) i { background: var(--coral); }
.atlas-row strong { font-size: .86rem; }
.atlas-row small { color: var(--muted); font-size: .72rem; }
.database-feature { background: linear-gradient(135deg, rgba(249,239,235,.78), rgba(252,251,249,0)); }
.database-feature-grid { display: grid; grid-template-columns: minmax(250px, .72fr) minmax(0, 1.28fr); gap: 44px; align-items: center; }
.database-feature-copy h2 { max-width: 520px; }
.database-feature-copy > p:not(.eyebrow) { max-width: 560px; margin: 20px 0 0; color: var(--muted); font-size: 1.05rem; }
.terminology-section { background: #fff; }
.terminology-flow { display: grid; grid-template-columns: minmax(0, 1.2fr) 24px minmax(0, .9fr) 24px minmax(0, .95fr); gap: 14px; align-items: stretch; }
.terminology-cloud,.terminology-method,.terminology-record { padding: 21px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--surface-soft); }
.terminology-cloud { background: #fff; }
.flow-label,.flow-step { display: block; margin: 0 0 13px; color: var(--coral); font-size: .7rem; font-weight: 800; letter-spacing: .12em; text-transform: uppercase; }
.term-chip-grid { display: flex; flex-wrap: wrap; gap: 8px; }
.term-chip-grid span { display: inline-flex; align-items: center; gap: 7px; padding: 7px 9px; border: 1px solid var(--line); border-radius: 999px; color: var(--ink); background: var(--surface); font-size: .74rem; line-height: 1.25; }
.term-chip-grid span::before { width: 7px; height: 7px; flex: 0 0 7px; border-radius: 50%; background: var(--coral); content: ''; }
.term-cloud-note { margin: 13px 0 0; color: var(--muted); font-size: .73rem; }
.terminology-method h3,.terminology-record h3 { margin: 0 0 10px; font-size: 1rem; }
.terminology-method p { margin: 0; color: var(--muted); font-size: .82rem; }
.terminology-arrow { display: grid; place-items: center; color: var(--coral); font-size: 1.5rem; font-weight: 700; }
.terminology-record { border-top: 4px solid var(--coral); background: #fff; }
.terminology-record ul { display: grid; gap: 7px; margin: 0 0 15px; padding-left: 18px; color: var(--muted); font-size: .76rem; }
.terminology-record a { color: var(--coral); font-size: .78rem; font-weight: 800; text-decoration: none; }
.terminology-record a:hover,.terminology-record a:focus-visible { text-decoration: underline; }
.terminology-note { margin: 13px 0 0; color: var(--muted); font-size: .73rem; }
.database-preview { display: block; overflow: hidden; border: 1px solid var(--line); border-radius: 22px; background: var(--surface); box-shadow: var(--shadow); text-decoration: none; transition: transform .18s ease, box-shadow .18s ease; }
.database-preview:hover, .database-preview:focus-visible { box-shadow: 0 28px 70px rgba(23,54,80,.16); transform: translateY(-3px); }
.database-preview-top { display: flex; align-items: baseline; justify-content: space-between; gap: 18px; padding: 18px 20px 15px; }
.database-preview-top strong { color: var(--navy); font-size: 1rem; }
.database-preview-top span { color: var(--muted); font-size: .74rem; }
.database-image-frame { aspect-ratio: 2.24 / 1; margin: 0 18px; overflow: hidden; border: 1px solid var(--line); border-radius: 14px; background: #eef4f7; }
.database-image-frame img { display: block; width: 100%; height: 100%; object-fit: cover; object-position: center; }
.database-preview-caption { display: flex; align-items: center; justify-content: space-between; gap: 16px; padding: 16px 20px 19px; color: var(--muted); font-size: .78rem; }
.database-preview-caption b { color: var(--navy); font-size: .82rem; }
.section { padding: 82px 0; border-top: 1px solid var(--line); }
.section-head { display: flex; align-items: end; justify-content: space-between; gap: 35px; margin-bottom: 34px; }
.section-head p { max-width: 520px; margin: 0; color: var(--muted); }
.section-head .eyebrow { margin-bottom: 11px; }
.cards { display: grid; grid-template-columns: repeat(3, 1fr); gap: 16px; }
.card { display: flex; flex-direction: column; min-height: 250px; padding: 23px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--surface); }
.card p { margin: 11px 0 0; color: var(--muted); font-size: .94rem; }
.card .card-link { margin-top: auto; padding-top: 27px; color: var(--navy); font-size: .84rem; font-weight: 760; text-decoration: none; }
.card .card-link:hover { color: var(--blue); }
.card-band { width: 100%; height: 7px; margin-bottom: 28px; border-radius: 7px; background: var(--blue); }
.card-band.teal { background: var(--teal); }
.card-band.purple { background: var(--purple); }
.card-band.gold { background: var(--gold); }
.card-band.coral { background: var(--coral); }
.topic-cloud { display: flex; flex-wrap: wrap; gap: 10px; }
.topic-chip { display: inline-flex; align-items: center; gap: 8px; padding: 10px 13px; border: 1px solid var(--line); border-radius: 999px; color: var(--ink); background: var(--surface); font-size: .84rem; font-weight: 650; text-decoration: none; }
.topic-chip:hover, .topic-chip:focus-visible { border-color: var(--blue); color: var(--blue); }
.topic-chip::before { content: ''; width: 8px; height: 8px; border-radius: 2px; background: var(--blue); }
.topic-chip:nth-child(3n + 2)::before { background: var(--teal); }
.topic-chip:nth-child(3n + 3)::before { background: var(--purple); }
.notice { display: grid; grid-template-columns: auto 1fr; gap: 16px; align-items: start; padding: 22px; border: 1px solid #ead9d0; border-radius: var(--radius); background: #f8eee8; }
.notice-mark { display: grid; place-items: center; width: 30px; height: 30px; border-radius: 9px; color: #fff; background: var(--blue); font-size: .8rem; font-weight: 800; }
.notice p { margin: 0; color: var(--ink); font-size: .9rem; }
.page-hero { padding: 76px 0 62px; border-bottom: 1px solid var(--line); background: linear-gradient(135deg, rgba(249,239,235,.9), rgba(252,251,249,0)); }
.page-hero h1 { max-width: 800px; font-size: clamp(2.75rem, 6vw, 5rem); }
.page-hero p:not(.eyebrow) { max-width: 720px; margin: 21px 0 0; color: var(--muted); font-size: 1.12rem; }
.page-hero.links-hero { padding: 32px 0 34px; }
.links-hero .breadcrumbs { margin-bottom: 10px; }
.links-hero h1 { max-width: none; font-size: clamp(2.2rem, 4.5vw, 3.7rem); line-height: 1.1; }
.links-hero p:not(.eyebrow) { margin-top: 12px; font-size: 1rem; }
.links-resources-section { padding-top: 42px; }
.studies-hero { padding: 25px 0 24px; }
.studies-hero .breadcrumbs { margin-bottom: 9px; }
.studies-hero h1 { max-width: none; font-size: clamp(2rem, 4vw, 3.1rem); line-height: 1.12; }
.studies-list-section { padding: 25px 0 60px; border-top: 0; }
.breadcrumbs { margin: 0 0 20px; color: var(--muted); font-size: .78rem; }
.breadcrumbs a { color: var(--muted); text-decoration: none; }
.breadcrumbs a:hover { color: var(--navy); }
.page-hero.about-hero { padding: 34px 0 28px; }
.page-hero.about-hero .breadcrumbs { margin-bottom: 0; }
.page-hero.about-hero h1 { max-width: none; font-size: clamp(2.1rem, 3.8vw, 3rem); line-height: 1.12; }
.about-project-section,.about-profile-section { padding: 54px 0; }
.about-profile-section { padding-bottom: 72px; }
.about-copy { max-width: 900px; }
.about-copy h2 { font-size: clamp(1.8rem, 3.1vw, 2.55rem); }
.about-copy > p:not(.eyebrow) { max-width: 820px; margin: 17px 0 0; color: var(--muted); }
.about-creator-layout { display: grid; grid-template-columns: minmax(0, 1fr) 176px; gap: 30px; align-items: start; }
.about-creator-text > p { max-width: 820px; margin: 17px 0 0; color: var(--muted); }
.about-portrait { margin: 17px 0 0; }
.about-portrait img { display: block; width: 100%; height: auto; border: 1px solid var(--line); border-radius: 14px; }
.about-portrait figcaption { margin-top: 7px; color: var(--muted); font-size: .72rem; }
.about-contact { display: flex; flex-wrap: wrap; gap: 0 9px; align-items: baseline; margin: 23px 0 0; color: var(--muted); font-size: .9rem; }
.about-contact strong { color: var(--navy); }
.about-copy a { color: var(--blue); font-weight: 700; text-decoration: none; }
.about-copy a:hover,.about-copy a:focus-visible { text-decoration: underline; }
.device-compare-section { background: linear-gradient(135deg, rgba(249,239,235,.7), rgba(252,251,249,0)); }
.device-table-wrap { overflow-x: auto; border: 1px solid var(--line); border-radius: 15px; background: var(--surface); }
.device-table { width: 100%; border-collapse: collapse; text-align: left; font-size: .87rem; }
.device-table caption { padding: 16px 18px; color: var(--muted); background: var(--surface); text-align: left; font-size: .8rem; }
.device-table th,.device-table td { padding: 14px 15px; border-bottom: 1px solid var(--line); vertical-align: top; }
.device-table th { color: var(--navy); background: var(--surface-soft); font-size: .76rem; letter-spacing: .025em; }
.device-table tbody tr:last-child td { border-bottom: 0; }
.device-table td:first-child { min-width: 145px; color: var(--navy); }
.device-table td:last-child { min-width: 185px; }
.device-table a { color: var(--blue); font-weight: 700; text-decoration: none; }
.device-table a:hover,.device-table a:focus-visible { text-decoration: underline; }
.device-format-table { min-width: 820px; }
.device-format-table td:first-child { min-width: 190px; }
.device-format-cell { display: flex; align-items: center; gap: 12px; }
.device-format-cell img { display: block; width: 58px; height: 58px; flex: 0 0 58px; object-fit: cover; border: 1px solid var(--line); border-radius: 10px; background: #fbf7f1; }
.device-example-list { display: grid; gap: 7px; margin: 0; padding: 0; list-style: none; }
.device-example-list li { position: relative; padding-left: 15px; }
.device-example-list li::before { position: absolute; top: .05em; left: 0; color: var(--coral); font-size: .72em; content: '●'; }
.device-format-note { margin: 14px 0 0; color: var(--muted); font-size: .82rem; }
.device-source-note { margin: 14px 0 0; color: var(--muted); font-size: .78rem; }
.device-visual-section { padding-top: 34px; padding-bottom: 22px; }
.device-visual-grid { display: grid; grid-template-columns: repeat(8, minmax(0, 1fr)); gap: 12px; }
.device-visual-grid figure { min-width: 0; margin: 0; }
.device-visual-grid img { display: block; width: 100%; aspect-ratio: 1; object-fit: cover; border: 1px solid var(--line); border-radius: 12px; background: #fbf7f1; }
.device-visual-grid figcaption { padding-top: 7px; color: var(--ink); font-size: .72rem; font-weight: 700; line-height: 1.25; text-align: center; }
.device-data-intro { max-width: 900px; margin: -8px 0 20px; color: var(--muted); }
.device-data-intro strong { color: var(--navy); }
.research-device-table { min-width: 760px; }
.research-device-table th:not(:first-child),.research-device-table td:not(:first-child) { text-align: center; white-space: nowrap; }
.device-parameter-table { min-width: 700px; }
.device-parameter-table th:not(:first-child),.device-parameter-table td:not(:first-child) { min-width: 190px; }
.device-example-note { margin: 12px 0 0; color: var(--muted); font-size: .76rem; line-height: 1.55; }
.device-example-note strong { color: var(--ink); }
.device-example-note a { color: var(--blue); font-weight: 700; text-decoration: none; }
.device-example-note a:hover,.device-example-note a:focus-visible { text-decoration: underline; }
.publication-details { max-width: 820px; margin-top: 28px; border: 0; border-top: 1px solid var(--line); border-bottom: 1px solid var(--line); border-radius: 0; background: transparent; }
.publication-details[open] { border-color: var(--line); box-shadow: none; }
.publication-details summary { padding: 15px 0; font-size: .92rem; }
.publication-details summary .publication-count { margin-left: auto; color: var(--muted); font-size: .77rem; font-weight: 600; }
.publication-details .publication-list li::before { top: 14px; left: 0; font-size: .66rem; }
.publication-details .publication-list a { grid-template-columns: minmax(0,1fr) auto; gap: 15px; padding: 11px 0 11px 29px; font-size: .84rem; }
.publication-details .publication-list span { font-size: .73rem; }
.split { display: grid; grid-template-columns: minmax(0, 1.06fr) minmax(280px, .94fr); gap: 42px; align-items: start; }
.panel { padding: 25px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--surface); }
.panel h3 { margin-bottom: 10px; }
.panel p { margin: 0; color: var(--muted); font-size: .93rem; }
.panel + .panel { margin-top: 14px; }
.external-link { display: flex; align-items: center; justify-content: space-between; gap: 20px; padding: 19px; border: 1px solid var(--line); border-radius: 13px; background: var(--surface-soft); text-decoration: none; }
.external-link strong { display: block; font-size: .96rem; }
.external-link span { display: block; margin-top: 3px; color: var(--muted); font-size: .78rem; }
.arrow { color: var(--blue); font-size: 1.4rem; }
.feature-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 16px; }
.feature { padding: 23px; border-top: 5px solid var(--blue); border-radius: var(--radius); background: var(--surface); box-shadow: 0 8px 30px rgba(23,54,80,.06); }
.feature:nth-child(2) { border-color: var(--teal); }
.feature:nth-child(3) { border-color: var(--purple); }
.feature h3 { margin-bottom: 9px; }
.feature p { margin: 0; color: var(--muted); font-size: .91rem; }
.publication-list { display: grid; gap: 0; margin: 0; padding: 0; list-style: none; counter-reset: publication; }
.publication-list li { position: relative; counter-increment: publication; border-top: 1px solid var(--line); }
.publication-list li::before { content: counter(publication, decimal-leading-zero); position: absolute; top: 20px; left: 19px; color: var(--blue); font-size: .72rem; font-weight: 800; letter-spacing: .08em; }
.publication-list a { display: grid; grid-template-columns: minmax(0, 1fr) auto; gap: 20px; align-items: center; padding: 18px 20px 18px 58px; color: var(--ink); text-decoration: none; }
.publication-list a:hover strong, .publication-list a:focus-visible strong { color: var(--blue); }
.publication-list strong { line-height: 1.3; }
.publication-list span { color: var(--muted); font-size: .8rem; text-align: right; }
.slide-deck { overflow: hidden; border: 1px solid var(--line); border-radius: 20px; background: var(--navy); box-shadow: var(--shadow); }
.slide-top { display: flex; justify-content: space-between; align-items: center; padding: 14px 17px; color: #d7e4ec; font-size: .76rem; }
.slide-top strong { color: #fff; font-size: .84rem; }
.slide { min-height: 320px; padding: 30px; background: linear-gradient(145deg, #f6fafc 0%, #e6f1f5 100%); }
.slide small { color: var(--blue); font-size: .74rem; font-weight: 800; letter-spacing: .13em; text-transform: uppercase; }
.slide h2 { max-width: 580px; margin-top: 17px; font-size: clamp(2rem, 4vw, 3.4rem); }
.slide p { max-width: 610px; margin: 18px 0 0; color: var(--muted); }
.slide-columns { display: grid; grid-template-columns: repeat(3, 1fr); gap: 10px; margin-top: 30px; }
.slide-column { padding: 14px; border-radius: 10px; background: #fff; }
.slide-column b { display: block; color: var(--navy); font-size: 1.3rem; }
.slide-column span { color: var(--muted); font-size: .72rem; }
.slide-bottom { display: flex; justify-content: space-between; padding: 12px 17px; color: #b8cbd7; font-size: .72rem; }
.study-link { display: flex; align-items: center; justify-content: space-between; gap: 24px; padding: 21px 0; border-bottom: 1px solid var(--line); text-decoration: none; }
.study-link:first-child { border-top: 1px solid var(--line); }
.study-link strong { font-size: .97rem; }
.study-link span { color: var(--muted); font-size: .82rem; }
.study-link:hover strong { color: var(--blue); }
.detail-grid { display: grid; grid-template-columns: repeat(2, 1fr); gap: 15px; }
details { border: 1px solid var(--line); border-radius: 14px; background: var(--surface); }
details[open] { border-color: #b7d2e2; box-shadow: 0 10px 30px rgba(61,128,181,.08); }
summary { display: flex; align-items: center; justify-content: space-between; gap: 16px; cursor: pointer; list-style: none; padding: 17px 18px; color: var(--navy); font-weight: 750; }
summary::-webkit-details-marker { display: none; }
summary::after { content: '+'; color: var(--blue); font-size: 1.3rem; font-weight: 400; }
details[open] summary::after { content: '–'; }
.detail-body { padding: 0 18px 18px; color: var(--muted); font-size: .9rem; }
.callout { padding: 28px; border-radius: 20px; color: #fff; background: var(--navy); }
.callout h2 { color: #fff; font-size: 2.2rem; }
.callout p { max-width: 630px; margin: 14px 0 0; color: #c5d5df; }
.callout .button { margin-top: 23px; border-color: #fff; color: var(--navy); background: #fff; }
.stat-grid { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 14px; }
.stat-card { padding: 21px; border: 1px solid var(--line); border-top: 5px solid var(--blue); border-radius: var(--radius); background: var(--surface); }
.stat-card:nth-child(2) { border-top-color: var(--teal); }
.stat-card:nth-child(3) { border-top-color: var(--purple); }
.stat-value { display: block; margin-top: 16px; color: var(--navy); font-size: clamp(2rem, 4vw, 3.1rem); font-weight: 800; letter-spacing: -.06em; line-height: 1; }
.stat-label { display: block; margin-top: 9px; color: var(--muted); font-size: .82rem; }
.chart-panel { padding: 25px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--surface); }
.chart-panel h3 { margin-bottom: 7px; }
.chart-panel > p { margin: 0 0 25px; color: var(--muted); font-size: .9rem; }
.milestone-scroll { overflow-x: auto; }
.milestone-svg { display: block; width: 100%; min-width: 680px; height: auto; overflow: visible; }
.chart-grid line { stroke: #e8e3df; stroke-width: 1; }
.chart-axis-labels text,.milestone-svg-years text { fill: var(--muted); font-size: 13px; font-family: inherit; }
.milestone-line { fill: none; stroke: var(--coral); stroke-width: 4; stroke-linecap: round; stroke-linejoin: round; }
.milestone-points circle { fill: var(--surface); stroke: var(--coral); stroke-width: 3; }
.milestone-svg-values text { fill: var(--ink); font-size: 13px; font-family: inherit; font-weight: 700; }
.milestone-svg-years text { font-size: 12px; }
.chart-caption { display: flex; justify-content: space-between; gap: 18px; margin-top: 14px; color: var(--muted); font-size: .75rem; }
.country-layout { display: grid; grid-template-columns: minmax(0, 1.65fr) minmax(280px, .75fr); gap: 18px; align-items: stretch; }
.country-columns { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: clamp(18px, 3vw, 38px); }
.bar-list { display: grid; gap: 13px; }
.bar-row { display: grid; grid-template-columns: 105px 1fr 55px; gap: 12px; align-items: center; font-size: .82rem; }
.bar-row > span:first-child { color: var(--ink); font-weight: 650; }
.bar-track { height: 11px; overflow: hidden; border-radius: 99px; background: #e6eef2; }
.bar-fill { width: calc(var(--width) * 1%); height: 100%; border-radius: inherit; background: var(--blue); }
.bar-row:nth-child(2n) .bar-fill { background: var(--teal); }
.bar-row strong { color: var(--navy); text-align: right; font-size: .8rem; }
.country-note { padding: 22px; border-radius: var(--radius); background: var(--surface-soft); }
.country-note h3 { margin-bottom: 12px; }
.country-note p { margin: 0; color: var(--muted); font-size: .9rem; }
.other-countries-row { max-width: 760px; margin-top: 5px; }
.country-chart-summary { margin: 0; color: var(--muted); font-size: .76rem; }
.model-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 15px; }
.model-card { padding: 23px; border: 1px solid var(--line); border-top: 5px solid var(--teal); border-radius: var(--radius); background: var(--surface); }
.model-card:nth-child(2) { border-top-color: var(--blue); }
.model-card:nth-child(3) { border-top-color: var(--coral); }
.model-card h3 { margin-bottom: 6px; }
.model-card .model-count { color: var(--navy); font-size: 1.75rem; font-weight: 800; letter-spacing: -.05em; }
.model-card .model-percent { display: block; margin-top: 16px; color: var(--teal); font-size: 1.75rem; font-weight: 800; letter-spacing: -.05em; }
.model-card:nth-child(2) .model-percent { color: var(--blue); }
.model-card:nth-child(3) .model-percent { color: var(--coral); }
.model-card p { margin: 4px 0 0; color: var(--muted); font-size: .82rem; }
.model-card .model-detail { margin-top: 18px; padding-top: 14px; border-top: 1px solid var(--line); color: var(--ink); font-size: .8rem; font-weight: 700; }
.human-design-list { display: grid; gap: 9px; margin-top: 17px; padding-top: 14px; border-top: 1px solid var(--line); font-size: .74rem; }
.human-design-list div { display: flex; justify-content: space-between; gap: 10px; }
.human-design-list span { color: var(--muted); }
.human-design-list strong { color: var(--teal); white-space: nowrap; }
.review-summary { display: grid; grid-template-columns: minmax(180px, .75fr) 2fr; gap: 18px 30px; align-items: center; margin-top: 20px; padding: 20px 22px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--surface-soft); }
.review-summary-heading h3 { margin-bottom: 4px; font-size: 1rem; }
.review-summary-heading p,.review-summary-note { margin: 0; color: var(--muted); font-size: .76rem; }
.review-summary-grid { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 12px; }
.review-summary-grid div { display: grid; gap: 4px; }
.review-summary-grid span { color: var(--muted); font-size: .74rem; }
.review-summary-grid strong { color: var(--ink); font-size: 1.35rem; letter-spacing: -.04em; }
.review-summary-note { grid-column: 2; margin-top: -11px; }
.review-summary-feature { grid-template-columns: minmax(210px, .8fr) 2fr; min-height: 148px; padding: 24px 26px; border: 1px solid #dfc8bd; border-top: 5px solid var(--blue); background: linear-gradient(110deg, #f7eeea, #fff 74%); box-shadow: 0 12px 32px rgba(70, 43, 35, .06); }
.review-summary-feature .review-summary-heading h3 { margin-bottom: 7px; font-size: 1.3rem; }
.review-summary-feature .review-summary-heading .eyebrow { margin-bottom: 8px; }
.review-summary-feature .review-summary-heading p:last-child { max-width: 275px; line-height: 1.45; }
.review-summary-feature .review-summary-grid { gap: 18px; }
.review-summary-feature .review-summary-grid div { min-height: 78px; align-content: center; padding-left: 18px; border-left: 1px solid #e4d5ce; }
.review-summary-feature .review-summary-grid span { color: var(--muted); font-size: .8rem; font-weight: 650; }
.review-summary-feature .review-summary-grid strong { color: var(--navy); font-size: clamp(1.8rem, 3vw, 2.5rem); line-height: 1.05; }
.species-mini { display: grid; grid-template-columns: 1fr 1fr; gap: 7px 13px; margin-top: 17px; padding-top: 14px; border-top: 1px solid var(--line); color: var(--muted); font-size: .74rem; }
.species-mini span { display: flex; justify-content: space-between; gap: 8px; }
.species-mini b { color: var(--ink); font-weight: 700; }
.species-mini em { color: var(--teal); font-style: normal; font-weight: 800; }
.species-mini-more { grid-column: 1 / -1; margin-top: 3px; color: var(--muted); font-size: .72rem; }
.species-mini-more summary { color: var(--blue); font-weight: 750; cursor: pointer; }
.species-mini-more p { margin: 7px 0 0; color: var(--muted); font-size: .72rem; line-height: 1.45; }
.species-mini-note { grid-column: 1 / -1; color: var(--muted); font-size: .68rem; }
.evidence-layout { display: grid; grid-template-columns: 1fr 1fr; gap: 15px; }
.evidence-list { display: grid; gap: 0; border: 1px solid var(--line); border-radius: var(--radius); overflow: hidden; background: var(--surface); }
.evidence-list h3 { padding: 19px 20px; color: #fff; background: var(--teal); font-size: 1rem; letter-spacing: 0; }
.evidence-list:nth-child(2) h3 { background: var(--blue); }
.evidence-list:nth-child(3) h3 { background: var(--coral); }
.evidence-list:nth-child(4) h3 { background: var(--gold); }
.evidence-item { display: flex; justify-content: space-between; gap: 20px; padding: 13px 20px; border-top: 1px solid var(--line); color: var(--ink); font-size: .84rem; }
.evidence-item strong { color: var(--navy); white-space: nowrap; }
.database-annotations { background: linear-gradient(180deg, #fbf7f4, var(--paper) 34%); }
.annotation-intro { max-width: 920px; margin: -12px 0 26px; color: var(--muted); font-size: .92rem; }
.annotation-grid { display: grid; grid-template-columns: repeat(6, minmax(0, 1fr)); gap: 15px; align-items: stretch; }
.annotation-card { overflow: hidden; border: 1px solid var(--line); border-radius: var(--radius); background: var(--surface); }
.annotation-card-study { grid-column: 1 / -1; }
.annotation-card-light,.annotation-card-critical,.annotation-card-context { grid-column: span 2; }
.annotation-card h3 { padding: 17px 19px; color: #fff; background: var(--teal); font-size: 1rem; letter-spacing: -.01em; }
.annotation-card-light h3 { background: #397bb6; }
.annotation-card-critical h3 { background: #c96374; }
.annotation-card-context h3 { background: #c88a2d; }
.annotation-items { display: grid; align-content: start; margin: 0; padding: 8px 17px 12px; list-style: none; }
.annotation-items-study { grid-template-columns: repeat(4, minmax(0, 1fr)); column-gap: 18px; }
.annotation-items li { display: grid; grid-template-columns: 25px minmax(0, 1fr) auto; gap: 8px; align-items: start; min-width: 0; padding: 12px 0; border-bottom: 1px solid var(--line); }
.annotation-items li:last-child { border-bottom: 0; }
.annotation-icon { padding-top: 1px; font-size: 1.08rem; line-height: 1.25; text-align: center; }
.annotation-copy { display: grid; gap: 2px; min-width: 0; line-height: 1.3; }
.annotation-copy strong { color: var(--ink); font-size: .76rem; }
.annotation-copy small { color: var(--muted); font-size: .68rem; line-height: 1.35; }
.annotation-items li > b { padding-top: 1px; color: var(--navy); font-size: .75rem; white-space: nowrap; }
.species-layout { display: grid; grid-template-columns: minmax(0, 1fr) minmax(250px, .82fr); gap: 35px; }
.species-list { display: grid; gap: 11px; }
.species-list h3 { margin-bottom: 4px; font-size: 1.05rem; }
.species-row { display: grid; grid-template-columns: 145px 1fr 44px; gap: 12px; align-items: center; color: var(--ink); font-size: .83rem; }
.species-row .bar-fill { background: var(--teal); }
.species-row strong { text-align: right; color: var(--navy); }
.source-note { margin-top: 18px; color: var(--muted); font-size: .75rem; }
.source-note a { color: var(--blue); }
.indication-tools { display: flex; align-items: end; justify-content: space-between; gap: 22px; margin-bottom: 24px; }
.search-field { display: grid; gap: 7px; width: min(360px, 100%); color: var(--muted); font-size: .78rem; font-weight: 700; }
.search-field input { width: 100%; min-height: 44px; padding: 0 13px; border: 1px solid var(--line); border-radius: 10px; color: var(--ink); background: var(--surface); font: inherit; font-weight: 500; }
.search-field input:focus { border-color: var(--blue); outline: 3px solid rgba(61,128,181,.18); }
.indication-directory { display: grid; grid-template-columns: repeat(2, 1fr); gap: 15px; }
.indication-category { overflow: hidden; border: 1px solid var(--line); border-radius: var(--radius); background: var(--surface); scroll-margin-top: 96px; }
.indication-category-head { display: flex; align-items: baseline; justify-content: space-between; gap: 15px; padding: 17px 19px; color: #fff; background: var(--blue); }
.indication-category:nth-child(4n + 2) .indication-category-head { background: var(--teal); }
.indication-category:nth-child(4n + 3) .indication-category-head { background: var(--purple); }
.indication-category:nth-child(4n + 4) .indication-category-head { background: var(--gold); }
.indication-category-head h3 { color: #fff; font-size: 1rem; letter-spacing: 0; }
.indication-category-head span { color: rgba(255,255,255,.88); font-size: .76rem; font-weight: 750; }
.indication-links { display: flex; flex-wrap: wrap; gap: 7px; padding: 17px 19px 19px; }
.indication-link { display: inline-block; padding: 7px 9px; border: 1px solid var(--line); border-radius: 7px; color: var(--ink); background: #fbfdfe; font-size: .78rem; line-height: 1.3; text-decoration: none; }
.indication-link:hover, .indication-link:focus-visible { border-color: var(--blue); color: var(--blue); background: var(--surface-soft); }
.empty-result { grid-column: 1 / -1; padding: 28px; border: 1px dashed var(--line); border-radius: var(--radius); color: var(--muted); background: var(--surface); text-align: center; }
.indication-overview-layout { display: grid; grid-template-columns: minmax(0, 1.4fr) minmax(270px, .72fr); gap: 22px; align-items: start; }
.indication-summary { padding: 26px; border: 1px solid var(--line); border-radius: var(--radius); background: var(--surface); }
.indication-summary h2 { margin: 0 0 16px; font-size: 1.5rem; letter-spacing: -.035em; }
.indication-summary h3 { margin: 24px 0 8px; font-size: 1.05rem; letter-spacing: -.02em; }
.indication-summary p { margin: 10px 0 0; color: var(--muted); }
.indication-aside { display: grid; gap: 14px; }
.indication-facts { display: grid; grid-template-columns: 1fr 1fr; gap: 10px; }
.indication-fact { min-height: 112px; padding: 15px; border: 1px solid var(--line); border-top: 4px solid var(--coral); border-radius: 13px; background: var(--surface); }
.indication-fact:nth-child(2n) { border-top-color: var(--teal); }
.indication-fact span { display: block; color: var(--muted); font-size: .72rem; font-weight: 700; }
.indication-fact strong { display: block; margin-top: 8px; color: var(--navy); font-size: 1.18rem; line-height: 1.2; }
.indication-country-panel { padding: 20px; border-radius: 14px; background: var(--surface-soft); }
.indication-country-panel h3 { margin: 0 0 13px; font-size: 1rem; letter-spacing: -.02em; }
.indication-country-list { display: flex; flex-wrap: wrap; gap: 7px; margin: 0; padding: 0; list-style: none; }
.indication-country-list li { padding: 4px 8px; border: 1px solid var(--line); border-radius: 999px; color: var(--ink); background: var(--surface); font-size: .72rem; }
.indication-source-note { margin: 18px 0 0; color: var(--muted); font-size: .76rem; }
.site-footer { margin-top: 25px; padding: 38px 0 45px; border-top: 1px solid var(--line); color: var(--muted); font-size: .78rem; }
.footer-grid { display: flex; justify-content: space-between; gap: 25px; }
.footer-grid p { max-width: 540px; margin: 0; }
.footer-nav { display: flex; flex-wrap: wrap; gap: 16px; }
.footer-nav a { text-decoration: none; }
.footer-nav a:hover { color: var(--navy); }
.sr-only { position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0,0,0,0); white-space: nowrap; border: 0; }
:focus-visible { outline: 3px solid #efae3a; outline-offset: 3px; }
@media (max-width: 980px) {
  .header-inner { position:relative; }
  .nav-toggle { display:block; }
  .site-nav { display:none; position:absolute; top:calc(100% + 8px); right:0; flex-direction:column; align-items:stretch; gap:0; min-width:250px; padding:8px; border:1px solid var(--line); border-radius:13px; background:var(--surface); box-shadow:var(--shadow); }
  .site-nav.is-open { display:flex; }
  .site-nav a { padding:11px 12px; }
  .hero-grid, .split { grid-template-columns: 1fr; gap: 38px; }
  .database-feature-grid { grid-template-columns: 1fr; gap: 30px; }
  .terminology-flow { grid-template-columns: 1fr; gap: 11px; }
  .terminology-arrow { transform: rotate(90deg); }
  .hero { padding-top: 67px; }
  .cards, .feature-grid { grid-template-columns: 1fr; }
  .stat-grid { grid-template-columns: repeat(2, 1fr); }
  .country-layout, .species-layout { grid-template-columns: 1fr; }
  .model-grid { grid-template-columns: 1fr; }
  .evidence-layout { grid-template-columns: 1fr; }
  .annotation-grid { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .annotation-card-study { grid-column: 1 / -1; }
  .annotation-card-light,.annotation-card-critical,.annotation-card-context { grid-column: span 1; }
  .annotation-items-study { grid-template-columns: repeat(2, minmax(0, 1fr)); }
  .indication-overview-layout { grid-template-columns: 1fr; }
  .card { min-height: 0; }
  .card .card-link { padding-top: 21px; }
  .section-head { display: block; }
  .section-head p { margin-top: 15px; }
  .publication-list a { grid-template-columns: 1fr; gap: 6px; padding-left: 48px; }
  .publication-list span { text-align: left; }
  .publication-details .publication-list a { grid-template-columns: 1fr; gap: 4px; padding: 11px 0 11px 29px; }
  .publication-details .publication-list span { text-align: left; }
}
@media (max-width: 1160px) and (min-width: 981px) {
  .header-inner { position: relative; }
  .nav-toggle { display: block; }
  .site-nav { display: none; position: absolute; top: calc(100% + 8px); right: 0; flex-direction: column; align-items: stretch; gap: 0; min-width: 250px; padding: 8px; border: 1px solid var(--line); border-radius: 13px; background: var(--surface); box-shadow: var(--shadow); }
  .site-nav.is-open { display: flex; }
  .site-nav a { padding: 11px 12px; }
  .device-visual-grid { grid-template-columns: repeat(4, minmax(0, 1fr)); }
}
@media (max-width: 1100px) {
  .device-visual-grid { grid-template-columns: repeat(4, minmax(0, 1fr)); }
}
@media (max-width: 680px) {
  .container { width: min(100% - 28px, 560px); }
  .header-inner { min-height: 66px; gap: 10px; }
  .brand { min-width: 0; gap: 8px; }
  .brand-mark { width: 34px; height: 34px; }
  .brand-text { font-size: .82rem; white-space: nowrap; }
  .nav-toggle { display: block; }
  .site-nav { display: none; position: absolute; top: 66px; left: 14px; right: 14px; flex-direction: column; align-items: stretch; gap: 0; padding: 8px; border: 1px solid var(--line); border-radius: 13px; background: var(--surface); box-shadow: var(--shadow); }
  .site-nav.is-open { display: flex; }
  .site-nav a { padding: 11px 12px; }
  .device-visual-grid { grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 10px; }
  .device-visual-grid figcaption { font-size: .78rem; }
  .country-columns { grid-template-columns: 1fr; }
  .bar-row { grid-template-columns: minmax(86px, 1fr) minmax(70px, 2fr) 48px; gap: 8px; }
  .review-summary { grid-template-columns: 1fr; gap: 14px; }
  .annotation-grid { grid-template-columns: 1fr; }
  .annotation-card-study { grid-column: auto; }
  .annotation-items-study { grid-template-columns: 1fr; }
  .review-summary-note { grid-column: 1; margin-top: -8px; }
  .review-summary-grid { gap: 8px; }
  .review-summary-grid span { font-size: .68rem; }
  .review-summary-grid strong { font-size: 1.15rem; }
  .review-summary-feature { grid-template-columns: 1fr; gap: 18px; padding: 20px; }
  .review-summary-feature .review-summary-grid { gap: 7px; }
  .review-summary-feature .review-summary-grid div { min-height: 67px; padding-left: 10px; }
  .review-summary-feature .review-summary-grid strong { font-size: 1.55rem; }
  .hero { padding: 57px 0 65px; }
  h1 { font-size: clamp(2.75rem, 14vw, 4.4rem); }
  .hero-copy { font-size: 1rem; }
  .page-hero { padding: 54px 0 47px; }
  .page-hero h1 { font-size: clamp(2.6rem, 13vw, 4.2rem); }
  .page-hero.links-hero { padding: 25px 0 27px; }
  .links-hero h1 { font-size: clamp(2.1rem, 10vw, 3rem); }
  .links-resources-section { padding-top: 30px; }
  .page-hero.about-hero { padding: 27px 0 23px; }
  .page-hero.about-hero h1 { font-size: 2.35rem; }
  .about-creator-layout { grid-template-columns: 1fr; gap: 18px; }
  .about-portrait { width: 120px; margin-top: 0; }
  .device-format-table-wrap { overflow: visible; border: 0; background: transparent; }
  .device-format-table { min-width: 0; }
  .device-format-table td:first-child { min-width: 0; }
  .device-format-cell img { width: 52px; height: 52px; flex-basis: 52px; }
  .device-table:not(.research-device-table) { display: block; }
  .device-table:not(.research-device-table) caption { padding: 0 0 11px; }
  .device-table:not(.research-device-table) thead { position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0,0,0,0); white-space: nowrap; border: 0; }
  .device-table:not(.research-device-table) tbody { display: grid; gap: 10px; }
  .device-table:not(.research-device-table) tbody tr { display: block; overflow: hidden; border: 1px solid var(--line); border-radius: 12px; background: var(--surface); }
  .device-table:not(.research-device-table) td { display: grid; grid-template-columns: 102px minmax(0,1fr); gap: 10px; min-width: 0; padding: 10px 12px; border-bottom: 1px solid var(--line); }
  .device-table:not(.research-device-table) td::before { content: attr(data-label); color: var(--muted); font-size: .7rem; font-weight: 750; }
  .device-table:not(.research-device-table) td:first-child,.device-table:not(.research-device-table) td:last-child { min-width: 0; }
  .device-table:not(.research-device-table) td:first-child { background: var(--surface-soft); }
  .device-parameter-table { min-width: 0; }
  .device-parameter-table th:not(:first-child),.device-parameter-table td:not(:first-child) { min-width: 0; }
  .research-device-table { min-width: 760px; }
  .studies-hero { padding: 22px 0 20px; }
  .studies-hero h1 { font-size: clamp(2rem, 8vw, 2.8rem); }
  .section { padding: 62px 0; }
  .studies-list-section { padding: 20px 0 44px; }
  .slide { min-height: 300px; padding: 22px; }
  .slide-columns { gap: 7px; }
  .slide-column { padding: 11px; }
  .slide-column b { font-size: 1rem; }
  .detail-grid { grid-template-columns: 1fr; }
  .stat-grid { grid-template-columns: 1fr 1fr; gap: 9px; }
  .stat-card { padding: 17px; }
  .stat-value { font-size: 2rem; }
  .indication-summary { padding: 19px; }
  .indication-facts { grid-template-columns: repeat(2,minmax(0,1fr)); }
  .bar-row { grid-template-columns: 82px 1fr 46px; gap: 8px; font-size: .75rem; }
  .species-row { grid-template-columns: 100px 1fr 37px; gap: 8px; font-size: .75rem; }
  .species-mini { grid-template-columns: 1fr; }
  .species-mini-more { grid-column: auto; }
  .indication-tools { display: block; }
  .search-field { width: 100%; margin-top: 18px; }
  .indication-directory { grid-template-columns: 1fr; }
  .chart-caption { display: block; }
  .chart-caption span { display: block; margin-top: 4px; }
  .footer-grid { display: block; }
  .footer-nav { margin-top: 18px; }
  .database-preview-top, .database-preview-caption { display: block; }
  .database-preview-top span, .database-preview-caption b { display: block; margin-top: 5px; }
}

.resource-grid { display:grid; grid-template-columns:1fr; gap:16px; }
.resource-group { padding:23px; border:1px solid var(--line); border-top:5px solid var(--blue); border-radius:var(--radius); background:var(--surface); }
.resource-group:nth-child(3n+2) { border-top-color:var(--teal); }
.resource-group:nth-child(3n+3) { border-top-color:var(--purple); }
.resource-group h2 { margin-top:4px; font-size:clamp(1.55rem, 3vw, 2.2rem); }
.resource-list { display:grid; gap:0; margin-top:17px; }
.resource-link { display:flex; align-items:flex-start; justify-content:space-between; gap:16px; padding:10px 0; border-top:1px solid var(--line); color:var(--ink); text-decoration:none; }
.resource-link:hover strong, .resource-link:focus-visible strong { color:var(--blue); }
.resource-link strong { display:block; line-height:1.3; }
.resource-link small { display:block; margin-top:5px; color:var(--muted); font-size:.78rem; line-height:1.45; }
.resource-link .arrow { flex:none; }

.trial-toolbar { display:grid; grid-template-columns:minmax(240px,1fr) auto; gap:14px; align-items:end; padding:19px; border:1px solid var(--line); border-radius:var(--radius); background:var(--surface); }
.trial-toolbar .search-field { width:100%; color:var(--ink); font-size:.84rem; font-weight:750; }
.trial-toolbar .search-field input { min-height:50px; padding:0 15px; border-color:#ddcec6; font-size:.92rem; font-weight:500; }
.trial-toolbar .button { margin-bottom:1px; white-space:nowrap; }
.study-filters { display:grid; gap:10px; margin-top:13px; }
.study-filter-row { display:grid; grid-template-columns:88px minmax(0,1fr); align-items:start; gap:11px; }
.study-filter-heading { padding-left:4px; color:var(--muted); font-size:.76rem; font-weight:750; }
.study-filter-row-secondary-start { padding-top:9px; border-top:1px solid var(--line); }
.study-filter-chips { display:flex; flex-wrap:wrap; gap:7px; }
.study-chip { min-height:33px; padding:5px 10px; border:1px solid var(--line); border-radius:999px; color:var(--ink); background:var(--surface); font:inherit; font-size:.72rem; font-weight:700; line-height:1.25; cursor:pointer; }
.study-filter-row-secondary .study-chip { min-height:31px; padding:5px 9px; font-size:.69rem; }
.study-chip:hover,.study-chip:focus-visible { border-color:var(--blue); }
.study-chip[aria-pressed="true"] { border-color:var(--blue); color:#fff; background:var(--blue); }
.study-filter-note { margin:12px 0 0; color:var(--muted); font-size:.72rem; }
.trial-results-status { min-height:25px; margin:19px 0 14px; color:var(--muted); font-size:.82rem; }
.trial-grid { display:grid; grid-template-columns:1fr; gap:10px; }
.trial-card { display:grid; grid-template-columns:minmax(0,1.2fr) minmax(335px,1fr) auto; align-items:center; gap:20px; min-width:0; padding:15px 19px; border:1px solid var(--line); border-radius:15px; background:var(--surface); transition:border-color .18s ease,box-shadow .18s ease; }
.trial-card:hover { border-color:#d7b7a9; box-shadow:0 9px 25px rgba(70,43,35,.07); }
.trial-study-main { min-width:0; }
.trial-status { display:inline-flex; align-items:center; width:max-content; max-width:100%; padding:4px 9px; border-radius:999px; color:#155b4e; background:#e6f3ed; font-size:.69rem; font-weight:800; line-height:1.4; }
.trial-status[data-status="NOT_YET_RECRUITING"] { color:#785313; background:#fbf1da; }
.trial-status[data-status="ENROLLING_BY_INVITATION"] { color:#654887; background:#f0eaf7; }
.trial-status[data-status="ACTIVE_NOT_RECRUITING"] { color:#36577f; background:#e9f0f7; }
.trial-status[data-status="SUSPENDED"] { color:#8a4a35; background:#f8eae4; }
.trial-updated { color:var(--muted); font-size:.67rem; text-align:right; }
.trial-title { margin:0; font-size:1.02rem; letter-spacing:-.02em; line-height:1.32; }
.trial-conditions { margin:5px 0 0; color:var(--muted); font-size:.76rem; line-height:1.4; }
.trial-meta { margin:7px 0 0; color:var(--muted); font-size:.68rem; line-height:1.4; }
.trial-facts { display:grid; grid-template-columns:repeat(3,minmax(0,1fr)); gap:10px; align-items:center; }
.trial-fact { display:flex; flex-direction:column; align-items:flex-start; gap:5px; min-width:0; }
.trial-fact-label { color:var(--muted); font-size:.61rem; font-weight:750; letter-spacing:.045em; line-height:1.25; text-transform:uppercase; }
.trial-fact-value { color:var(--ink); font-size:.9rem; line-height:1.3; }
.trial-card-side { display:grid; justify-items:end; gap:6px; }
.trial-record { display:inline-flex; align-items:center; gap:5px; color:var(--blue); font-size:.74rem; font-weight:780; text-decoration:none; white-space:nowrap; }
.trial-record:hover,.trial-record:focus-visible { color:var(--navy); text-decoration:underline; }
.trial-error[hidden] { display:none !important; }
.trial-error { display:grid; justify-items:start; gap:8px; padding:21px; border:1px solid #e9bdb1; border-radius:var(--radius); color:var(--ink); background:#fff6f2; }
.trial-error span { color:var(--muted); font-size:.88rem; }
.trial-error a { color:var(--blue); font-size:.85rem; font-weight:750; }
.registry-section { background:linear-gradient(180deg,rgba(249,239,235,.5),rgba(252,251,249,0)); }
.registry-notice { margin-bottom:20px; }
.registry-grid { display:grid; grid-template-columns:repeat(3,minmax(0,1fr)); gap:13px; }
.registry-card { display:grid; grid-template-columns:1fr auto; align-content:start; gap:8px 14px; min-height:178px; padding:20px; border:1px solid var(--line); border-top:4px solid var(--teal); border-radius:15px; background:var(--surface); text-decoration:none; transition:transform .18s ease,box-shadow .18s ease; }
.registry-card:nth-child(3n + 2) { border-top-color:var(--blue); }
.registry-card:nth-child(3n + 3) { border-top-color:var(--purple); }
.registry-card:hover,.registry-card:focus-visible { box-shadow:var(--shadow); transform:translateY(-2px); }
.registry-region { grid-column:1 / -1; color:var(--blue); font-size:.67rem; font-weight:800; letter-spacing:.1em; text-transform:uppercase; }
.registry-card strong { color:var(--navy); font-size:.94rem; line-height:1.35; }
.registry-card > span:not(.registry-region) { grid-column:1 / -1; color:var(--muted); font-size:.78rem; line-height:1.5; }
.registry-card .arrow { grid-column:2; grid-row:2; align-self:center; }

@media (max-width: 980px) {
  .registry-grid { grid-template-columns:repeat(2,minmax(0,1fr)); }
  .trial-toolbar { grid-template-columns:minmax(0,1fr) auto; }
  .trial-card { grid-template-columns:minmax(0,1fr); gap:13px; }
  .trial-facts { grid-template-columns:repeat(3,minmax(0,1fr)); }
  .trial-card-side { display:flex; align-items:center; justify-content:space-between; gap:12px; padding-top:10px; border-top:1px solid var(--line); }
}
@media (max-width: 680px) {
  .trial-toolbar { grid-template-columns:1fr; gap:12px; padding:14px; }
  .study-filter-row { grid-template-columns:1fr; gap:5px; }
  .trial-grid,.registry-grid { grid-template-columns:1fr; }
  .trial-card { gap:12px; padding:15px; }
  .trial-facts { grid-template-columns:repeat(2,minmax(0,1fr)); gap:13px 9px; }
  .trial-fact-value { font-size:.85rem; }
  .trial-card-side { align-items:flex-start; }
  .registry-card { min-height:0; }
}

.journal-impact-layout { display:grid; grid-template-columns:minmax(0,1fr); gap:16px; align-items:stretch; }
.journal-impact-panel,.us-states-panel { padding:25px; border:1px solid var(--line); border-radius:var(--radius); background:var(--surface); }
.journal-impact-panel { border-top:5px solid var(--blue); }
.journal-impact-metrics { display:grid; grid-template-columns:repeat(2,minmax(0,1fr)); gap:16px; }
.journal-impact-metrics div { display:grid; gap:3px; }
.journal-impact-metrics strong { color:var(--navy); font-size:clamp(2.1rem,4vw,3.2rem); letter-spacing:-.065em; line-height:1; }
.journal-impact-metrics span { color:var(--muted); font-size:.82rem; }
.journal-impact-caveat { max-width:720px; margin:17px 0 24px; color:var(--muted); font-size:.79rem; line-height:1.55; }
.journal-impact-panel h3 { margin-bottom:5px; font-size:1.08rem; }
.journal-example-list { display:grid; grid-template-columns:repeat(2,minmax(0,1fr)); column-gap:26px; margin:0; padding:0; list-style:none; }
.journal-example-list li { display:flex; justify-content:space-between; gap:16px; padding:12px 0; border-top:1px solid var(--line); }
.journal-example-list li > span { display:grid; gap:2px; }
.journal-example-list a { color:var(--ink); font-size:.84rem; font-weight:750; text-decoration:none; }
.journal-example-list a:hover,.journal-example-list a:focus-visible { color:var(--blue); text-decoration:underline; }
.journal-example-list small { color:var(--muted); font-size:.73rem; }
.journal-example-list b { color:var(--blue); font-size:.9rem; }
.us-states-panel { background:var(--surface-soft); }
.us-states-panel .eyebrow { margin-bottom:10px; }
.us-state-total { display:block; color:var(--navy); font-size:clamp(1.9rem,3.2vw,2.6rem); letter-spacing:-.06em; line-height:1.05; }
.us-state-total span { color:var(--blue); }
.us-states-panel > p:not(.eyebrow):not(.state-code-note) { margin:12px 0; color:var(--muted); font-size:.81rem; }
.state-code-list { display:flex; flex-wrap:wrap; gap:6px; margin:0; padding:0; list-style:none; }
.state-code-list li { min-width:34px; padding:3px 6px; border:1px solid #e6d7cf; border-radius:7px; color:var(--ink); background:rgba(255,255,255,.7); font-size:.68rem; font-weight:750; text-align:center; }
.state-code-note { margin:13px 0 0; color:var(--muted); font-size:.69rem; line-height:1.45; }
.article-index-card { display:grid; grid-template-columns:1fr auto; gap:14px 25px; align-items:center; padding:27px; border:1px solid var(--line); border-left:5px solid var(--blue); border-radius:var(--radius); background:var(--surface); text-decoration:none; }
.article-index-card:hover { box-shadow:var(--shadow); }
.article-index-card .eyebrow { grid-column:1 / -1; margin:0; }
.article-index-card h2 { margin-bottom:8px; font-size:clamp(1.65rem,3vw,2.35rem); }
.article-index-card p:not(.eyebrow) { max-width:760px; margin:0; color:var(--muted); }
.article-index-card .article-card-link { color:var(--blue); font-weight:800; white-space:nowrap; }
.article-page-hero { padding-bottom:47px; }
.article-page-hero h1 { max-width:900px; font-size:clamp(2.8rem,6vw,5rem); }
.article-page-hero .article-deck { max-width:790px; margin:20px 0 0; color:var(--muted); font-size:1.12rem; }
.article-meta { margin:16px 0 0; color:var(--muted); font-size:.78rem; }
.article-body { max-width:860px; margin:0 auto; }
.article-body h2 { margin:45px 0 16px; font-size:clamp(1.7rem,3.4vw,2.45rem); }
.article-body h3 { margin:27px 0 10px; font-size:1.25rem; }
.article-body p { margin:0 0 17px; color:var(--ink); }
.article-body .article-lead { color:var(--muted); font-size:1.1rem; line-height:1.72; }
.article-table-wrap { margin:24px 0; overflow-x:auto; border:1px solid var(--line); border-radius:14px; background:var(--surface); }
.article-table { width:100%; border-collapse:collapse; font-size:.85rem; }
.article-table th,.article-table td { padding:13px 15px; border-bottom:1px solid var(--line); text-align:left; vertical-align:top; }
.article-table th { color:var(--navy); background:var(--surface-soft); font-size:.76rem; }
.article-table tr:last-child td { border-bottom:0; }
.article-table td:first-child { min-width:150px; font-weight:750; }
.article-caution { margin:26px 0; padding:18px 20px; border-left:4px solid var(--gold); border-radius:0 12px 12px 0; color:var(--ink); background:#faf4e8; }
.article-references { margin-top:47px; padding-top:24px; border-top:1px solid var(--line); }
.article-references h2 { margin-top:0; }
.article-references ol { display:grid; gap:9px; padding-left:22px; color:var(--muted); font-size:.8rem; }
.article-references a { color:var(--ink); }

.database-hero { padding:31px 0 38px; }
.database-hero .breadcrumbs { margin-bottom:23px; }
.database-hero-grid { display:grid; grid-template-columns:minmax(0,1fr) minmax(320px,.72fr); gap:50px; align-items:end; }
.database-hero-grid h1 { max-width:760px; font-size:clamp(2.7rem,5.4vw,4.7rem); }
.database-deck { max-width:610px; margin:0; color:var(--muted); font-size:1.03rem; }
.database-hero .actions { margin-top:20px; }
.database-browser-section { padding-top:51px; }
.database-browser-intro { display:flex; justify-content:space-between; align-items:end; gap:36px; margin-bottom:24px; }
.database-browser-intro .eyebrow { margin-bottom:9px; }
.database-browser-intro h2 { font-size:clamp(1.8rem,3.3vw,2.7rem); }
.database-browser-intro > p { max-width:535px; margin:0; color:var(--muted); font-size:.92rem; }
.database-browser { overflow:hidden; border:1px solid var(--line); border-radius:20px; background:var(--surface); box-shadow:0 14px 40px rgba(70,43,35,.055); }
.database-toolbar { display:grid; grid-template-columns:minmax(250px,1.45fr) repeat(3,minmax(130px,.65fr)); gap:12px; padding:20px; border-bottom:1px solid var(--line); background:linear-gradient(180deg,#fff,#fdfbf9); }
.database-toolbar label { display:grid; gap:6px; min-width:0; color:var(--muted); font-size:.72rem; font-weight:750; }
.database-toolbar input,.database-toolbar select { width:100%; min-height:43px; padding:0 12px; border:1px solid var(--line); border-radius:9px; color:var(--ink); background:#fff; font:inherit; font-size:.82rem; font-weight:550; }
.database-toolbar input:focus,.database-toolbar select:focus { border-color:var(--blue); outline:3px solid rgba(195,90,82,.14); }
.database-model-filters { display:flex; flex-wrap:wrap; align-items:center; gap:7px; padding:14px 20px; border-bottom:1px solid var(--line); }
.database-model-filters > span { margin-right:5px; color:var(--muted); font-size:.73rem; font-weight:750; }
.database-model-filters button,.database-reset,.database-pagination button,.database-error button { min-height:32px; padding:5px 11px; border:1px solid var(--line); border-radius:999px; color:var(--ink); background:#fff; font:inherit; font-size:.73rem; font-weight:700; cursor:pointer; }
.database-model-filters button[aria-pressed="true"] { border-color:var(--blue); color:#fff; background:var(--blue); }
.database-model-filters button:hover,.database-reset:hover,.database-pagination button:not(:disabled):hover,.database-error button:hover { border-color:var(--blue); }
.database-results-head { display:flex; justify-content:space-between; align-items:center; gap:14px; min-height:50px; padding:8px 20px; }
.database-results-head p { margin:0; color:var(--muted); font-size:.78rem; }
.database-reset { border-color:transparent; color:var(--blue); }
.database-loading { display:flex; align-items:center; gap:11px; min-height:160px; padding:30px; color:var(--muted); font-size:.86rem; }
.database-spinner { width:19px; height:19px; border:2px solid var(--line); border-top-color:var(--blue); border-radius:50%; animation:database-spin .8s linear infinite; }
@keyframes database-spin { to { transform:rotate(360deg); } }
.database-error[hidden],.database-table-wrap[hidden],.database-pagination[hidden],.database-loading[hidden] { display:none !important; }
.database-error { display:grid; justify-items:start; gap:8px; margin:18px 20px; padding:20px; border:1px solid #e9bdb1; border-radius:14px; background:#fff6f2; }
.database-error strong { color:var(--navy); }
.database-error span { color:var(--muted); font-size:.83rem; }
.database-error a { color:var(--blue); font-size:.82rem; font-weight:750; text-decoration:none; }
.database-error button { margin-top:3px; }
.database-table-wrap { overflow-x:auto; border-top:1px solid var(--line); }
.database-table { width:100%; border-collapse:collapse; font-size:.82rem; }
.database-table th { padding:12px 14px; color:var(--muted); background:var(--surface-soft); font-size:.67rem; font-weight:800; letter-spacing:.055em; text-align:left; text-transform:uppercase; white-space:nowrap; }
.database-table td { padding:13px 14px; border-top:1px solid var(--line); vertical-align:top; }
.database-table tbody tr:hover { background:#fdfaf8; }
.database-table th:first-child,.database-table td:first-child { padding-left:20px; }
.database-table th:last-child,.database-table td:last-child { padding-right:20px; }
.database-publication { display:grid; gap:4px; min-width:255px; max-width:510px; }
.database-publication strong { color:var(--navy); font-size:.84rem; line-height:1.4; }
.database-publication span { color:var(--muted); font-size:.72rem; line-height:1.4; }
.database-indication { display:grid; gap:3px; min-width:135px; max-width:220px; }
.database-indication strong { font-size:.76rem; line-height:1.4; }
.database-indication span { color:var(--muted); font-size:.7rem; line-height:1.35; }
.database-model-tag { display:inline-flex; align-items:center; padding:4px 8px; border-radius:999px; color:#42627f; background:#eaf1f6; font-size:.68rem; font-weight:750; white-space:nowrap; }
.database-model-tag[data-model="Animal"] { color:#9c4e46; background:#f8ece8; }
.database-model-tag[data-model="In vitro"] { color:#a16620; background:#fbf1df; }
.database-model-tag[data-model="Review"] { color:#68528e; background:#f1edf7; }
.database-model-tag[data-model="Other"] { color:var(--muted); background:#f1efed; }
.database-country { min-width:100px; color:var(--muted); font-size:.74rem; }
.database-year { color:var(--ink); font-size:.77rem; font-weight:750; white-space:nowrap; }
.database-pagination { display:flex; justify-content:space-between; align-items:center; gap:15px; padding:13px 20px; border-top:1px solid var(--line); }
.database-pagination > span { color:var(--muted); font-size:.76rem; }
.database-pagination > div { display:flex; gap:7px; }
.database-pagination button { border-radius:8px; }
.database-pagination button:disabled { opacity:.45; cursor:default; }
.database-source-note { margin:0; padding:12px 20px 16px; color:var(--muted); font-size:.71rem; line-height:1.5; }

@media (max-width: 760px) {
  .journal-impact-layout,.journal-example-list { grid-template-columns:1fr; }
  .journal-impact-panel,.us-states-panel { padding:19px; }
  .article-index-card { grid-template-columns:1fr; padding:21px; }
  .article-index-card .article-card-link { justify-self:start; }
  .article-page-hero h1 { font-size:clamp(2.5rem,12vw,4rem); }
  .article-table { min-width:610px; }
  .database-hero-grid { grid-template-columns:1fr; gap:17px; }
  .database-hero-grid h1 { font-size:clamp(2.5rem,11vw,3.8rem); }
  .database-browser-intro { display:grid; gap:12px; }
  .database-toolbar { grid-template-columns:repeat(2,minmax(0,1fr)); padding:14px; }
  .database-search { grid-column:1 / -1; }
  .database-model-filters { gap:6px; padding:12px 14px; }
  .database-model-filters > span { flex-basis:100%; }
  .database-results-head { padding:8px 14px; }
  .database-table { font-size:.78rem; }
  .database-table thead { position:absolute; width:1px; height:1px; padding:0; margin:-1px; overflow:hidden; clip:rect(0,0,0,0); white-space:nowrap; border:0; }
  .database-table,.database-table tbody { display:block; width:100%; }
  .database-table tbody { padding:10px; }
  .database-table tbody tr { display:grid; grid-template-columns:minmax(0,1fr) auto; gap:0 12px; margin-bottom:9px; overflow:hidden; border:1px solid var(--line); border-radius:12px; background:#fff; }
  .database-table tbody tr:last-child { margin-bottom:0; }
  .database-table td { display:grid; grid-template-columns:90px minmax(0,1fr); gap:8px; padding:9px 11px; border-top:1px solid #f0e9e4; }
  .database-table td::before { content:attr(data-label); color:var(--muted); font-size:.65rem; font-weight:750; }
  .database-table td:first-child { grid-column:1 / -1; padding:12px; border-top:0; background:var(--surface-soft); }
  .database-publication { min-width:0; max-width:none; }
  .database-pagination { padding:11px 14px; }
}