{ "metadata": { "title": "Photobiomodulation mentions in clinical guidelines and consensus documents", "schema_version": "1.4", "checked_on": "2026-10-16", "collection_revision": "expansion_06", "document_count": 136, "statement_count": 238, "added_document_count": 7, "added_statement_count": 8, "historical_statement_count": 18, "directions": { "recommended": 36, "may_consider": 44, "against": 47, "insufficient_evidence": 45, "no_benefit": 6, "descriptive_support": 27, "mention_only": 13, "expert_protocol": 20 }, "document_types": { "clinical_practice_guideline": 105, "procedure_guidance": 2, "society_consensus": 5, "expert_consensus_article": 9, "expert_consensus": 3, "position_paper": 4, "guideline_update_note": 2, "clinical_practice_statement": 3, "task_force_report": 1, "policy_statement": 2 }, "scope": "Broad targeted public-web research, not an exhaustive systematic review.", "counting_unit": "One statement / population / outcome setting per row; rows are not independent guidelines, trials, or patients. Historical editions are retained and identified.", "grading": "Strength and certainty are transcribed as reported by each source. Different grading systems are not harmonized or ranked against one another. Grouped recommendations are identified.", "terminology": "Searches included photobiomodulation, PBM, PBMT, low-level laser/light therapy, LLLT, cold laser, laser therapy, laser acupuncture, and Finnish equivalents. Some source recommendations combine LLLT with HILT; this is recorded.", "source_selection": "Professional-society guidelines, public guideline bodies, society consensus, policy and position documents, and relevant expert consensus. Document type and therapeutic direction remain separate. RCTs, systematic reviews without recommendations, insurer policies, manufacturer materials, educational fact sheets and draft technical reports were not counted as issued guidelines.", "versions": "Known supersession is flagged. A complete latest-version check for all jurisdictions was not performed. 2019 PBM and 2020 MASCC consolidated mucositis publications are represented as one guideline update; the APTA listing of AAOS knee guidance is not double-counted.", "verification": "Verification depth and source-check date are recorded per document and row; earlier source-check dates are retained. APTA plantar-fasciitis final grade B is verified. Official COG reproductions verify POGO 2021 grades. Original OARSI supplements verify subgroup ratings. HTW clinical benefit is distinguished from adoption economics. Japanese no-recommendation grades remain separate from supportive narrative wording. Official EuroGuiDerm graphical tables were visually checked; red-light positions do not inherit blue-light recommendations. Canadian AGA is abstract-limited. AAO AMD and AAO-HNSF tinnitus agenda are official mentions only. Qualifications and Source issues retain group scope, wording and citation problems.", "language": "English workbook and import data follow the PBM Science project language; Finnish CSV provides a readable companion.", "search_log_note": "The retained log contains 533 queries from iterative public-web research. It is not a prespecified reproducible systematic-review search strategy; some original exploratory queries were not retained.", "country_scope_checked_on": "2026-10-16", "country_scope_definition": "Country / scope identifies the issuing organization, development panel or explicitly stated guideline area. International and regional labels are retained instead of assigning a headquarters country. It is not author nationality or proof of applicability in every listed jurisdiction. Not stated means the retrieved source did not establish a country or scope." }, "documents": [ { "id": "mascc_mucositis", "organization": "MASCC/ISOO", "title": "Clinical practice guidelines for the management of mucositis secondary to cancer therapy", "edition_year": 2020, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC7540329/", "verification_depth": "full_text", "version_status": "2019/2020 update", "doi": "10.1002/cncr.33100", "notes": "PBM-specific recommendations appeared in 2019; the 2020 guideline consolidates the same update. Counted as one guideline document/family here.", "supporting_urls": [ "https://pubmed.ncbi.nlm.nih.gov/31286228/", "https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7540329/fullTextXML" ], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: MASCC/ISOO. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC7540329/" ] }, { "id": "pogo_mucositis", "organization": "Pediatric Oncology Group of Ontario (POGO); endorsed by Children's Oncology Group", "title": "Clinical practice guideline for the prevention of oral and oropharyngeal mucositis in pediatric cancer and hematopoietic stem cell transplant patients: 2021 update", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/34252760/", "verification_depth": "official_recommendation_summary", "version_status": "2021 update", "doi": "10.1016/j.ejca.2021.05.013", "notes": "The official COG endorsed-guideline compilation, version 27 August 2025, reproduces the 2021 recommendations with strength and evidence quality on pp. 42–44. It resolves the previous abstract-only grade gap. The COG endorsement is not counted as a second guideline.", "supporting_urls": [ "https://www.pogo.ca/healthcare/clinical-practice-guidelines/mucositis/", "https://childrensoncologygroup.org/wp-content/uploads/2026/05/COG_SC_Comprehensive-Includes-all-COG-Endorsed-Supportive-Care-Guidelines_Document_27AUG2025-new-logo.pdf" ], "checked_on": "2026-10-16", "country_scope": "Canada", "country_scope_kind": "country", "country_scope_basis": "POGO is the Pediatric Oncology Group of Ontario, Canada. The US Children's Oncology Group endorsement is retained in the document record and is not treated as a second issuer country or document.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/34252760/" ] }, { "id": "nice_mucositis", "organization": "NICE", "title": "Low-level laser therapy for preventing or treating oral mucositis caused by radiotherapy or chemotherapy (HTG472; formerly IPG615)", "edition_year": 2018, "publication_year": 2018, "document_type": "procedure_guidance", "url": "https://www.nice.org.uk/guidance/HTG472/chapter/1-recommendations", "verification_depth": "full_text", "version_status": "Reviewed edition", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United Kingdom", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: NICE. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.nice.org.uk/guidance/HTG472/chapter/1-recommendations" ] }, { "id": "esmo_mucositis", "organization": "ESMO", "title": "Management of oral and gastrointestinal mucosal injury: ESMO Clinical Practice Guidelines for diagnosis, treatment, and follow-up", "edition_year": 2015, "publication_year": 2015, "document_type": "clinical_practice_guideline", "url": "https://www.annalsofoncology.org/article/S0923-7534(19)47173-1/fulltext", "verification_depth": "full_text", "version_status": "2015 edition", "doi": "", "notes": "Mucositis recommendations explicitly draw on the then-current MASCC/ISOO guidance; these are not independent patient data.", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "Europe", "country_scope_kind": "region", "country_scope_basis": "Issuing organization or panel identified in the source: ESMO. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.annalsofoncology.org/article/S0923-7534(19)47173-1/fulltext" ] }, { "id": "mascc_dermatitis", "organization": "MASCC Oncodermatology Study Group", "title": "Multinational Association of Supportive Care in Cancer clinical practice guidelines for the prevention and management of acute radiation dermatitis: international Delphi consensus-based recommendations", "edition_year": 2023, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://mascc.org/wp-content/uploads/2023/03/Guideline_ARD_part_2_2023-03-27.pdf", "verification_depth": "full_text", "version_status": "2023 edition", "doi": "10.1016/S1470-2045(23)00067-0", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: MASCC Oncodermatology Study Group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://mascc.org/wp-content/uploads/2023/03/Guideline_ARD_part_2_2023-03-27.pdf" ] }, { "id": "asco_xerostomia", "organization": "ISOO/MASCC/ASCO", "title": "Salivary Gland Hypofunction and/or Xerostomia Induced by Nonsurgical Cancer Therapies: ISOO/MASCC/ASCO Guideline", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/34283635/", "verification_depth": "official_recommendation_summary", "version_status": "2021 edition", "doi": "10.1200/JCO.21.01208", "notes": "The official MASCC guideline summary was read.", "supporting_urls": [ "https://mascc.memberclicks.net/assets/Guidelines-Tools/OralCare/oralcare_ISOO_MASCC_ASCO_Salivary_Gland_guideline_summary_July_2021.pdf" ], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: ISOO/MASCC/ASCO. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/34283635/" ] }, { "id": "asco_orn", "organization": "ISOO/MASCC/ASCO", "title": "Prevention and Management of Osteoradionecrosis in Patients With Head and Neck Cancer Treated With Radiation Therapy", "edition_year": 2024, "publication_year": 2024, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/38691821/", "verification_depth": "abstract", "version_status": "2024 edition", "doi": "10.1200/JCO.23.02750", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: ISOO/MASCC/ASCO. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/38691821/" ] }, { "id": "apta_cts_2026", "organization": "APTA Orthopedics / APTA Hand and Upper Extremity", "title": "Hand Pain and Sensory Deficits: Carpal Tunnel Syndrome: Revision 2026", "edition_year": 2026, "publication_year": 2026, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2026.0301", "verification_depth": "full_text", "version_status": "2026 revision; replaces 2019", "doi": "10.2519/jospt.2026.0301", "notes": "The recommendation combines LLLT and HILT.", "supporting_urls": [ "https://www.orthopt.org/uploads/content_files/files/Hand_Pain_CTS_jospt.2026.0301_new.pdf" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: APTA Orthopedics / APTA Hand and Upper Extremity. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2026.0301" ] }, { "id": "aaos_cts_2024", "organization": "AAOS (endorsed by ASSH)", "title": "Management of Carpal Tunnel Syndrome", "edition_year": 2024, "publication_year": 2024, "document_type": "clinical_practice_guideline", "url": "https://www.aaos.org/globalassets/quality-and-practice-resources/carpal-tunnel/carpal-tunnel-2024/cts-cpg.pdf", "verification_depth": "full_text", "version_status": "2024 revision; replaces 2016", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: AAOS (endorsed by ASSH). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.aaos.org/globalassets/quality-and-practice-resources/carpal-tunnel/carpal-tunnel-2024/cts-cpg.pdf" ] }, { "id": "aaos_cts_2016", "organization": "AAOS", "title": "Management of Carpal Tunnel Syndrome", "edition_year": 2016, "publication_year": 2016, "document_type": "clinical_practice_guideline", "url": "https://www.aaos.org/globalassets/quality-and-practice-resources/carpal-tunnel/cts_cpg_4-25-19.pdf", "verification_depth": "full_text", "version_status": "Historical; replaced by AAOS 2024", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: AAOS. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.aaos.org/globalassets/quality-and-practice-resources/carpal-tunnel/cts_cpg_4-25-19.pdf" ] }, { "id": "apta_cts_2019", "organization": "APTA Academy of Orthopaedic Physical Therapy / Hand and Upper Extremity", "title": "Hand Pain and Sensory Deficits: Carpal Tunnel Syndrome", "edition_year": 2019, "publication_year": 2019, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2019.0301", "verification_depth": "historical_recommendation_reproduced_in_2026_full_text", "version_status": "Historical; replaced by APTA 2026", "doi": "10.2519/jospt.2019.0301", "notes": "The 2019 recommendation is reproduced verbatim in the 2026 revision, PDF p. 32. The standalone 2019 full text was blocked.", "supporting_urls": [ "https://www.orthopt.org/uploads/content_files/files/Hand_Pain_CTS_jospt.2026.0301_new.pdf" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: APTA Academy of Orthopaedic Physical Therapy / Hand and Upper Extremity. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2019.0301" ] }, { "id": "apta_rotator", "organization": "APTA-supported international guideline panel / Academy of Orthopaedic Physical Therapy", "title": "Rotator Cuff Tendinopathy Diagnosis, Nonsurgical Medical Care, and Rehabilitation: A Clinical Practice Guideline", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2025.13182", "verification_depth": "full_text", "version_status": "2025 edition", "doi": "10.2519/jospt.2025.13182", "notes": "Laser recommendation 31 concerns calcific tendinopathy.", "supporting_urls": [ "https://www.orthopt.org/uploads/content_files/files/Rotator_Cuff_CPG.pdf" ], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "The guideline states that an international steering committee developed it; it received Canadian and APTA funding. Labelled by the international development panel, not a single funding country.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2025.13182" ] }, { "id": "apta_radius", "organization": "APTA Academy of Orthopaedic Physical Therapy / Hand and Upper Extremity", "title": "Distal Radius Fracture Rehabilitation", "edition_year": 2024, "publication_year": 2024, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2024.0301", "verification_depth": "full_text", "version_status": "2024 edition", "doi": "10.2519/jospt.2024.0301", "notes": "Laser appears within a recommendation covering several physical agents.", "supporting_urls": [ "https://www.orthopt.org/uploads/content_files/files/mehta_et_al_2024_distal_radius_fracture_rehabilitation.pdf" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: APTA Academy of Orthopaedic Physical Therapy / Hand and Upper Extremity. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2024.0301" ] }, { "id": "apta_heel", "organization": "APTA Academy of Orthopaedic Physical Therapy", "title": "Heel Pain – Plantar Fasciitis: Revision 2023", "edition_year": 2023, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2023.0303", "verification_depth": "full_text", "version_status": "2023 revision", "doi": "10.2519/jospt.2023.0303", "notes": "Final published 2023 PDF retrieved during expansion 02. The final B grade and short-term pain recommendation within rehabilitation are verified; the earlier draft-only flag is resolved.", "supporting_urls": [ "https://www.orthopt.org/uploads/content_files/files/Heel_Pain_Plantar_Fasciitis_Revision_2023.pdf", "https://www.orthopt.org/uploads/content_files/files/koc_et_al_2023_heel_pain_plantar_fasciitis_revision_2023.pdf" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: APTA Academy of Orthopaedic Physical Therapy. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2023.0303" ] }, { "id": "apta_elbow", "organization": "APTA Academy of Hand and Upper Extremity / Academy of Orthopaedic Physical Therapy", "title": "Lateral Elbow Pain and Muscle Function Impairments", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2022.0302", "verification_depth": "full_text", "version_status": "2022 edition", "doi": "10.2519/jospt.2022.0302", "notes": "Evidence includes both low- and high-intensity laser therapy.", "supporting_urls": [ "https://www.orthopt.org/uploads/content_files/files/lucado_et_al_2022_lateral_elbow_pain_and_muscle_function_impairments.pdf" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: APTA Academy of Hand and Upper Extremity / Academy of Orthopaedic Physical Therapy. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2022.0302" ] }, { "id": "aaos_knee", "organization": "AAOS", "title": "Management of Osteoarthritis of the Knee (Non-Arthroplasty), Third Edition", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://www.aaos.org/globalassets/quality-and-practice-resources/osteoarthritis-of-the-knee/oak3cpg.pdf", "verification_depth": "full_text", "version_status": "2021 third edition", "doi": "", "notes": "APTA lists this AAOS guideline in its CPG resources. That listing is not counted as a separate APTA guideline.", "supporting_urls": [ "https://www.apta.org/patient-care/evidence-based-practice-resources/cpgs/management-of-osteoarthritis-of-the-knee-non-arthroplasty" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: AAOS. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.aaos.org/globalassets/quality-and-practice-resources/osteoarthritis-of-the-knee/oak3cpg.pdf" ] }, { "id": "apta_ankle", "organization": "APTA Academy of Orthopaedic Physical Therapy", "title": "Ankle Stability and Movement Coordination Impairments: Lateral Ankle Ligament Sprains Revision 2021", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2021.0302", "verification_depth": "full_text", "version_status": "2021 revision", "doi": "10.2519/jospt.2021.0302", "notes": "", "supporting_urls": [ "https://www.orthopt.org/uploads/content_files/files/jospt.2021.0302.pdf" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: APTA Academy of Orthopaedic Physical Therapy. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2021.0302" ] }, { "id": "apta_achilles", "organization": "APTA Academy of Orthopaedic Physical Therapy", "title": "Achilles Pain, Stiffness, and Muscle Power Deficits: Midportion Achilles Tendinopathy Revision 2024", "edition_year": 2024, "publication_year": 2024, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2024.0302", "verification_depth": "full_text", "version_status": "2024 revision", "doi": "10.2519/jospt.2024.0302", "notes": "Published final article retrieved from IFSPT.", "supporting_urls": [ "https://ifspt.org/wp-content/uploads/2025/05/Achilles.pdf" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: APTA Academy of Orthopaedic Physical Therapy. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2024.0302" ] }, { "id": "apta_neck", "organization": "APTA Orthopaedic Section", "title": "Neck Pain: Revision 2017", "edition_year": 2017, "publication_year": 2017, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2017.0302", "verification_depth": "full_text", "version_status": "2017 revision", "doi": "10.2519/jospt.2017.0302", "notes": "", "supporting_urls": [ "https://www.orthopt.org/uploads/content_files/files/Neck%20Pain%20CPG%20-%20Revision%202017.pdf" ], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: APTA Orthopaedic Section. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2017.0302" ] }, { "id": "apta_lymphedema", "organization": "Academy of Oncologic Physical Therapy of APTA", "title": "Interventions for Breast Cancer–Related Lymphedema", "edition_year": 2020, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC7412854/", "verification_depth": "full_text", "version_status": "2020 edition", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Academy of Oncologic Physical Therapy of APTA. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC7412854/" ] }, { "id": "isl_2023", "organization": "International Society of Lymphology", "title": "The Diagnosis and Treatment of Peripheral Lymphedema: 2023 Consensus Document", "edition_year": 2023, "publication_year": 2023, "document_type": "society_consensus", "url": "https://isl.arizona.edu/sites/default/files/2024-11/THE-DIAGNOSIS-AND-TREATMENT-OF-PERIPHERAL-LYMPHEDEMA-2023-CONSENSUS-DOCUMENT-OF-THE-INTERNATIONAL-SOCIETY-OF-LYMPHOLOGY.pdf", "verification_depth": "full_text", "version_status": "2023 revision; newer than slide's 2020 edition", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: International Society of Lymphology. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://isl.arizona.edu/sites/default/files/2024-11/THE-DIAGNOSIS-AND-TREATMENT-OF-PERIPHERAL-LYMPHEDEMA-2023-CONSENSUS-DOCUMENT-OF-THE-INTERNATIONAL-SOCIETY-OF-LYMPHOLOGY.pdf" ] }, { "id": "isl_2020", "organization": "International Society of Lymphology", "title": "The Diagnosis and Treatment of Peripheral Lymphedema: 2020 Consensus Document", "edition_year": 2020, "publication_year": 2020, "document_type": "society_consensus", "url": "https://isl.arizona.edu/sites/default/files/2021-09/Consensus%20Document-SM.pdf", "verification_depth": "full_text", "version_status": "Historical; updated by ISL 2023", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: International Society of Lymphology. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://isl.arizona.edu/sites/default/files/2021-09/Consensus%20Document-SM.pdf" ] }, { "id": "acp_back", "organization": "American College of Physicians", "title": "Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain", "edition_year": 2017, "publication_year": 2017, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/28192789/", "verification_depth": "abstract", "version_status": "2017 edition", "doi": "10.7326/M16-2367", "notes": "The abstract contains the full recommendation 2 and its stated strength.", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Physicians. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/28192789/" ] }, { "id": "nass_back", "organization": "North American Spine Society", "title": "Diagnosis and Treatment of Low Back Pain", "edition_year": 2020, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://www.spine.org/Portals/0/Documents/ResearchClinicalCare/Guidelines/LowBackPain.pdf", "verification_depth": "full_text", "version_status": "2020 edition", "doi": "", "notes": "Combines low- and high-level laser evidence in several recommendations; laser acupuncture is evaluated separately.", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "North America", "country_scope_kind": "region", "country_scope_basis": "The issuing body is the North American Spine Society. Its named regional remit is shown rather than assigning all guidance to its US headquarters.", "country_scope_source_urls": [ "https://www.spine.org/Portals/0/Documents/ResearchClinicalCare/Guidelines/LowBackPain.pdf" ] }, { "id": "va_back", "organization": "US Department of Veterans Affairs / Department of Defense", "title": "Clinical Practice Guideline for the Diagnosis and Treatment of Low Back Pain", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://www.healthquality.va.gov/guidelines/Pain/lbp/VADoDLBPCPGFinal508.pdf", "verification_depth": "full_text", "version_status": "2022 edition", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: US Department of Veterans Affairs / Department of Defense. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.healthquality.va.gov/guidelines/Pain/lbp/VADoDLBPCPGFinal508.pdf" ] }, { "id": "optima_neck", "organization": "Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration", "title": "Management of neck pain and associated disorders", "edition_year": 2016, "publication_year": 2016, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/26984876/", "verification_depth": "full_text_author_article_reproduction", "version_status": "2016 edition", "doi": "", "notes": "Full article reproduced by Chiro.org; bibliographic identity checked against PubMed.", "supporting_urls": [ "https://chiro.org/Chronic_Neck/Management_of_Neck_Pain_and_Associated.shtml" ], "checked_on": "2026-10-15", "country_scope": "Canada", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/26984876/" ] }, { "id": "optima_shoulder", "organization": "Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration", "title": "Noninvasive management of soft tissue disorders of the shoulder: a clinical practice guideline", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/33942459/", "verification_depth": "full_text_author_article_reproduction", "version_status": "2021 edition", "doi": "10.1002/ejp.1788", "notes": "Full article reproduced by Chiro.org; bibliographic identity checked against PubMed.", "supporting_urls": [ "https://chiro.org/Non-pharmacologic_Therapy/Noninvasive_Management_of_Soft_Tissue.shtml" ], "checked_on": "2026-10-15", "country_scope": "Canada", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/33942459/" ] }, { "id": "jstmj", "organization": "Japanese Society for the Temporomandibular Joint", "title": "Clinical practice guidelines in primary treatment for temporomandibular disorders: 2023 edition", "edition_year": 2023, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/40399068/", "verification_depth": "full_text", "version_status": "2023 guideline; English publication 2025", "doi": "10.2186/jpr.JPR_D_24_00168", "notes": "Separates guideline edition year from publication year.", "supporting_urls": [ "https://www.jstage.jst.go.jp/article/jpr/advpub/0/advpub_JPR_D_24_00168/_pdf" ], "checked_on": "2026-10-15", "country_scope": "Japan", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Japanese Society for the Temporomandibular Joint. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/40399068/" ] }, { "id": "bmj_tmd", "organization": "BMJ Rapid Recommendations international panel", "title": "Management of chronic pain associated with temporomandibular disorders", "edition_year": 2023, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://www.bmj.com/content/383/bmj-2023-076227", "verification_depth": "full_text", "version_status": "2023 edition", "doi": "10.1136/bmj-2023-076227", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: BMJ Rapid Recommendations international panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.bmj.com/content/383/bmj-2023-076227" ] }, { "id": "nice_oa", "organization": "NICE", "title": "Osteoarthritis in over 16s: diagnosis and management (NG226)", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://www.nice.org.uk/guidance/ng226/chapter/Recommendations", "verification_depth": "full_text", "version_status": "Reviewed edition", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United Kingdom", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: NICE. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.nice.org.uk/guidance/ng226/chapter/Recommendations" ] }, { "id": "racgp_oa", "organization": "Royal Australian College of General Practitioners", "title": "Guideline for the management of knee and hip osteoarthritis, Second Edition", "edition_year": 2018, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://www.racgp.org.au/FSDEDEV/media/documents/Clinical%20Resources/Guidelines/Joint%20replacement/Guideline-for-the-management-of-knee-and-hip-OA-2nd-edition.pdf", "verification_depth": "full_text", "version_status": "2018 second edition", "doi": "", "notes": "", "supporting_urls": [ "https://www.racgp.org.au/clinical-resources/clinical-guidelines/key-racgp-guidelines/view-all-racgp-guidelines/knee-and-hip-osteoarthritis/recommendations/non-pharmacological-interventions/electrotherapies" ], "checked_on": "2026-10-15", "country_scope": "Australia", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Royal Australian College of General Practitioners. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.racgp.org.au/FSDEDEV/media/documents/Clinical%20Resources/Guidelines/Joint%20replacement/Guideline-for-the-management-of-knee-and-hip-OA-2nd-edition.pdf" ] }, { "id": "iwgdf", "organization": "International Working Group on the Diabetic Foot", "title": "Guidelines on interventions to enhance healing of foot ulcers in people with diabetes: 2023 update", "edition_year": 2023, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://iwgdfguidelines.org/wp-content/uploads/2023/07/IWGDF-2023-07-Wound-Healing-Guideline.pdf", "verification_depth": "full_text", "version_status": "Reviewed edition", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: International Working Group on the Diabetic Foot. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://iwgdfguidelines.org/wp-content/uploads/2023/07/IWGDF-2023-07-Wound-Healing-Guideline.pdf" ] }, { "id": "whs_pressure", "organization": "Wound Healing Society", "title": "WHS Guidelines for the Treatment of Pressure Ulcers – 2023 update", "edition_year": 2023, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11403384/", "verification_depth": "full_text", "version_status": "2023 update; journal issue 2024", "doi": "", "notes": "The article was first published in 2023; it appears in a 2024 issue.", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "WHS describes itself as the premier international organization for wound healing science and clinical practice. The society scope is used rather than its US administrative base.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC11403384/", "https://woundheal.org/about/" ] }, { "id": "va_tinnitus", "organization": "US Department of Veterans Affairs / Department of Defense", "title": "Clinical Practice Guideline for Tinnitus", "edition_year": 2024, "publication_year": 2024, "document_type": "clinical_practice_guideline", "url": "https://www.healthquality.va.gov/guidelines/CD/tinnitus/VADoD-CPG-Tinnitus-Full-CPG-2024_Final_508.pdf", "verification_depth": "full_text", "version_status": "Reviewed edition", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: US Department of Veterans Affairs / Department of Defense. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.healthquality.va.gov/guidelines/CD/tinnitus/VADoD-CPG-Tinnitus-Full-CPG-2024_Final_508.pdf" ] }, { "id": "s3_tinnitus", "organization": "German Society for Otorhinolaryngology, Head and Neck Surgery (DGHNO-KHC)", "title": "S3 Guideline: Chronic Tinnitus", "edition_year": 2021, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC9581878/", "verification_depth": "full_text", "version_status": "2021 guideline; English publication 2022", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: German Society for Otorhinolaryngology, Head and Neck Surgery (DGHNO-KHC). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC9581878/" ] }, { "id": "s3_aga", "organization": "European Dermatology Forum", "title": "S3 guideline for the treatment of androgenetic alopecia in women and in men: 2017 update", "edition_year": 2017, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/29178529/", "verification_depth": "full_text", "version_status": "2017 full guideline; short journal version 2018", "doi": "10.1111/jdv.14624", "notes": "The full EDF guideline was read, not only the short abstract.", "supporting_urls": [ "https://turkderm.org.tr/turkdermData/Uploads/files/S3_guideline_androgenetic_alopecia_update_final-version.pdf" ], "checked_on": "2026-10-15", "country_scope": "Europe", "country_scope_kind": "region", "country_scope_basis": "Issuing organization or panel identified in the source: European Dermatology Forum. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/29178529/" ] }, { "id": "jaad_consensus", "organization": "International multidisciplinary expert panel (Maghfour et al.)", "title": "Evidence-based consensus on the clinical application of photobiomodulation", "edition_year": 2025, "publication_year": 2025, "document_type": "expert_consensus_article", "url": "https://pubmed.ncbi.nlm.nih.gov/40253006/", "verification_depth": "abstract_and_author_repository_abstract", "version_status": "2025 consensus", "doi": "10.1016/j.jaad.2025.04.031", "notes": "Publication in JAAD does not establish an American Academy of Dermatology organizational endorsement. Indication-specific grades were not available in the abstract.", "supporting_urls": [ "https://scholarlycommons.henryford.com/dermatology_articles/1019/" ], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: International multidisciplinary expert panel (Maghfour et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/40253006/" ] }, { "id": "china_dermatology", "organization": "Chinese dermatology expert consensus panel (35 experts; Bai et al.)", "title": "Chinese Expert Consensus on the Clinical Application of Photobiomodulation Therapy in Dermatology (2025)", "edition_year": 2025, "publication_year": 2026, "document_type": "expert_consensus", "url": "https://www.ovid.com/jnls/ijdv/abstract/10.1097/jd9.0000000000000456~chinese-expert-consensus-on-the-clinical-application-of", "verification_depth": "full_text", "version_status": "2025 consensus; published 2026", "doi": "10.1097/JD9.0000000000000456", "notes": "Grades are the panel's reported grades. The article's main text and tables, rather than the added machine-generated FAQ, were used.", "supporting_urls": [ "https://mednexus.org/doi/full/10.1097/JD9.0000000000000456" ], "checked_on": "2026-10-15", "country_scope": "China", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Chinese dermatology expert consensus panel (35 experts; Bai et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.ovid.com/jnls/ijdv/abstract/10.1097/jd9.0000000000000456~chinese-expert-consensus-on-the-clinical-application-of" ] }, { "id": "walt_2022", "organization": "World Association for Photobiomodulation Therapy (WALT)", "title": "Photobiomodulation therapy in management of cancer therapy-induced side effects: WALT position paper 2022", "edition_year": 2022, "publication_year": 2022, "document_type": "position_paper", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC9468822/", "verification_depth": "full_text", "version_status": "2022 position paper", "doi": "10.3389/fonc.2022.927685", "notes": "The paper distinguishes oral-mucositis clinical practice guidelines from expert technical consensus for other indications, explicitly citing inadequate data for clinical treatment guidelines for those other indications.", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: World Association for Photobiomodulation Therapy (WALT). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC9468822/" ] }, { "id": "walt_orofacial", "organization": "World Association for Photobiomodulation Therapy (WALT)", "title": "Photobiomodulation Therapy in the Management of Orofacial Neuropathic Pain—WALT Position Paper 2026", "edition_year": 2026, "publication_year": 2026, "document_type": "position_paper", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12898000/", "verification_depth": "full_text", "version_status": "2026 position paper", "doi": "10.3390/jcm15031304", "notes": "Distinguishes BMS clinical practice guidance from expert consensus for trigeminal and post-herpetic neuralgia.", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: World Association for Photobiomodulation Therapy (WALT). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC12898000/" ] }, { "id": "fi_neck", "organization": "Suomalainen Lääkäriseura Duodecim; Käypä hoito working group", "title": "Niskakipu (aikuiset)", "edition_year": 2017, "publication_year": 2017, "document_type": "clinical_practice_guideline", "url": "https://www.kaypahoito.fi/hoi20010", "verification_depth": "full_text_and_evidence_summary", "version_status": "In force on source page; published 16 January 2017", "doi": "", "notes": "", "supporting_urls": [ "https://www.kaypahoito.fi/nak08828" ], "checked_on": "2026-10-15", "country_scope": "Finland", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Suomalainen Lääkäriseura Duodecim; Käypä hoito working group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.kaypahoito.fi/hoi20010" ] }, { "id": "fi_tmd", "organization": "Suomalainen Lääkäriseura Duodecim; Käypä hoito working group", "title": "Purentaelimistön kipu ja toimintahäiriöt (TMD)", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://www.kaypahoito.fi/hoi50057", "verification_depth": "full_text_and_evidence_summary", "version_status": "Under revision on source page; published 16 April 2021", "doi": "", "notes": "", "supporting_urls": [ "https://www.kaypahoito.fi/nak08036" ], "checked_on": "2026-10-15", "country_scope": "Finland", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Suomalainen Lääkäriseura Duodecim; Käypä hoito working group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.kaypahoito.fi/hoi50057" ] }, { "id": "fi_ra", "organization": "Suomalainen Lääkäriseura Duodecim; Käypä hoito working group", "title": "Nivelreuma", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://www.kaypahoito.fi/hoi21010", "verification_depth": "full_text_and_evidence_summary", "version_status": "Under revision on source page; published 18 February 2022", "doi": "", "notes": "Laser evidence summary dated 2015 remains linked from the 2022 guideline.", "supporting_urls": [ "https://www.kaypahoito.fi/nak08409" ], "checked_on": "2026-10-15", "country_scope": "Finland", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Suomalainen Lääkäriseura Duodecim; Käypä hoito working group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.kaypahoito.fi/hoi21010" ] }, { "id": "fi_shoulder", "organization": "Suomalainen Lääkäriseura Duodecim; Käypä hoito working group", "title": "Olkapään jännevaivat", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://www.kaypahoito.fi/hoi50099", "verification_depth": "full_text", "version_status": "In force on source page; published 12 April 2022", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "Finland", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Suomalainen Lääkäriseura Duodecim; Käypä hoito working group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.kaypahoito.fi/hoi50099" ] }, { "id": "fi_legulcer", "organization": "Suomalainen Lääkäriseura Duodecim; Käypä hoito working group", "title": "Krooninen alaraajahaava", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://www.kaypahoito.fi/hoi50058", "verification_depth": "full_text", "version_status": "In force on source page; published 9 April 2021", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "Finland", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Suomalainen Lääkäriseura Duodecim; Käypä hoito working group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.kaypahoito.fi/hoi50058" ] }, { "id": "aao_amd", "organization": "American Academy of Ophthalmology", "title": "Age-Related Macular Degeneration Preferred Practice Pattern 2024: official December 2025 update note", "edition_year": 2024, "publication_year": 2025, "document_type": "guideline_update_note", "url": "https://www.aao.org/education/preferred-practice-pattern/age-related-macular-degeneration-ppp", "verification_depth": "official_update_note_only", "version_status": "2024 PPP; December 2025 clarification", "doi": "", "notes": "The official note verifies a PBM mention and FDA de novo authorization wording. The complete PPP treatment recommendation was not accessible; no endorsement is inferred.", "supporting_urls": [], "checked_on": "2026-10-15", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American Academy of Ophthalmology. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.aao.org/education/preferred-practice-pattern/age-related-macular-degeneration-ppp" ] }, { "id": "sio_asco_breast", "organization": "Society for Integrative Oncology; ASCO endorsement", "title": "Integrative Therapies During and After Breast Cancer Treatment: ASCO Endorsement of the SIO Clinical Practice Guideline", "edition_year": 2018, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13123314/", "verification_depth": "full_text", "version_status": "2018 ASCO endorsement of SIO 2017", "doi": "", "notes": "The endorsement and the SIO 2017 source are represented as one recommendation family; not independent patient evidence.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Society for Integrative Oncology; ASCO endorsement. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC13123314/" ] }, { "id": "china_om_consensus", "organization": "Chinese multidisciplinary oral mucositis expert consensus panel (Xia et al.)", "title": "Expert consensus on the prevention and treatment of oral mucositis", "edition_year": 2025, "publication_year": 2025, "document_type": "expert_consensus", "url": "https://www.nature.com/articles/s41368-025-00382-8", "verification_depth": "full_text", "version_status": "2025 consensus", "doi": "10.1038/s41368-025-00382-8", "notes": "The photobiotherapy prevention section was read. No laser-specific recommendation grade was assigned unless explicitly stated.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "China", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Chinese multidisciplinary oral mucositis expert consensus panel (Xia et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.nature.com/articles/s41368-025-00382-8" ] }, { "id": "apta_pfp", "organization": "Academy of Orthopaedic Physical Therapy of APTA", "title": "Patellofemoral Pain: Clinical Practice Guidelines", "edition_year": 2019, "publication_year": 2019, "document_type": "clinical_practice_guideline", "url": "https://www.jospt.org/doi/10.2519/jospt.2019.0302", "verification_depth": "full_text", "version_status": "2019 edition", "doi": "10.2519/jospt.2019.0302", "notes": "Published final text retrieved from IFSPT.", "supporting_urls": [ "https://ifspt.org/wp-content/uploads/2025/05/Patellofemoral-Pain.pdf" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Academy of Orthopaedic Physical Therapy of APTA. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jospt.org/doi/10.2519/jospt.2019.0302" ] }, { "id": "kngf_neck", "organization": "Royal Dutch Society for Physical Therapy (KNGF)", "title": "Clinical Practice Guideline for Physical Therapy Assessment and Treatment in Patients With Nonspecific Neck Pain", "edition_year": 2016, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://academic.oup.com/ptj/article/98/3/162/4689128", "verification_depth": "full_text", "version_status": "2016 KNGF guideline; journal publication 2018", "doi": "10.1093/ptj/pzx118", "notes": "Published article retrieved from the Vrije Universiteit repository. The 2016 society practice document was also inspected.", "supporting_urls": [ "https://research.vu.nl/ws/files/80445325/Clinical_Practice_Guideline_for_Physical_Therapy_Assessment_and_Treatment_in_Patients_With_Nonspecific_Neck_Pain.pdf/1000", "https://www.kennisplatformfysiotherapie.nl/app/uploads/sites/2/2024/10/neck_pain_practice_guidelines_2016.pdf" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Netherlands", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Royal Dutch Society for Physical Therapy (KNGF). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://academic.oup.com/ptj/article/98/3/162/4689128" ] }, { "id": "kngf_ra", "organization": "Royal Dutch Society for Physical Therapy (KNGF)", "title": "KNGF-richtlijn Reumatoïde artritis", "edition_year": 2018, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://reumanetnl.nl/wp-content/uploads/2019/06/KNGF-praktijkrichtlijn-RA-2018.pdf", "verification_depth": "full_text", "version_status": "2018 revision; newer than 2008 document", "doi": "", "notes": "Dutch full practice guideline and explanatory notes; reviewed in the source language.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Netherlands", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Royal Dutch Society for Physical Therapy (KNGF). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://reumanetnl.nl/wp-content/uploads/2019/06/KNGF-praktijkrichtlijn-RA-2018.pdf" ] }, { "id": "kngf_oa", "organization": "Royal Dutch Society for Physical Therapy (KNGF)", "title": "KNGF-richtlijn Artrose heup-knie", "edition_year": 2018, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://reumanetnl.nl/wp-content/uploads/2019/06/KNGF-praktijkrichtlijn-Artrose-heup-knie-2018.pdf", "verification_depth": "full_text", "version_status": "2018 edition", "doi": "", "notes": "Dutch full practice guideline and explanatory note 26; a small possible adjunctive effect is acknowledged but the recommendation remains against.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Netherlands", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Royal Dutch Society for Physical Therapy (KNGF). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://reumanetnl.nl/wp-content/uploads/2019/06/KNGF-praktijkrichtlijn-Artrose-heup-knie-2018.pdf" ] }, { "id": "german_neck", "organization": "German College of General Practitioners and Family Physicians (DEGAM) / interdisciplinary S3 panel", "title": "Nicht-spezifische Nackenschmerzen: S3-Leitlinie 053-007", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://www.degam.de/files/Inhalte/Leitlinien-Inhalte/Dokumente/DEGAM-S3-Leitlinien/053-007-nackenschmerz/oeffentlich/degam-s3-ll-nackenschmerzen-2025-langfassung.pdf", "verification_depth": "full_text", "version_status": "2025 edition", "doi": "", "notes": "Official DEGAM PDF; recommendation 29.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: German College of General Practitioners and Family Physicians (DEGAM) / interdisciplinary S3 panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.degam.de/files/Inhalte/Leitlinien-Inhalte/Dokumente/DEGAM-S3-Leitlinien/053-007-nackenschmerz/oeffentlich/degam-s3-ll-nackenschmerzen-2025-langfassung.pdf" ] }, { "id": "german_back", "organization": "German National Disease Management Guideline programme (BÄK / KBV / AWMF)", "title": "Nationale VersorgungsLeitlinie Nicht-spezifischer Kreuzschmerz, 2. Auflage, Version 1", "edition_year": 2017, "publication_year": 2017, "document_type": "clinical_practice_guideline", "url": "https://www.kvberlin.de/fileadmin/user_upload/qs_leistungen/computertomographie/ct_nat_versorgungsleitlinie_kreuzschmerz.pdf", "verification_depth": "full_text", "version_status": "Historical 2017 edition; current validity not established", "doi": "", "notes": "Record retains the 2017 wording; does not claim this is an active 2026 guideline.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: German National Disease Management Guideline programme (BÄK / KBV / AWMF). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.kvberlin.de/fileadmin/user_upload/qs_leistungen/computertomographie/ct_nat_versorgungsleitlinie_kreuzschmerz.pdf" ] }, { "id": "german_supportive", "organization": "Leitlinienprogramm Onkologie (DKG / DKH / AWMF)", "title": "S3-Leitlinie Supportive Therapie bei onkologischen PatientInnen, Langversion 2.0", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://www.leitlinienprogramm-onkologie.de/fileadmin/user_upload/Downloads/Leitlinien/Supportivtherapie/Version_2/LL_Supportive_Therapie_Langversion_2.0.pdf", "verification_depth": "full_text", "version_status": "Version 2.0, April 2025", "doi": "", "notes": "German original text distinguishes chemotherapy, HSCT, radiation-induced mucositis, dermatitis prevention and radiation-induced skin ulcers.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Leitlinienprogramm Onkologie (DKG / DKH / AWMF). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.leitlinienprogramm-onkologie.de/fileadmin/user_upload/Downloads/Leitlinien/Supportivtherapie/Version_2/LL_Supportive_Therapie_Langversion_2.0.pdf" ] }, { "id": "german_wounds", "organization": "German Society for Wound Healing and Wound Treatment (DGfW) / interdisciplinary S3 guideline panel", "title": "Lokaltherapie schwerheilender und/oder chronischer Wunden aufgrund von peripherer arterieller Verschlusskrankheit, Diabetes mellitus oder chronischer venöser Insuffizienz", "edition_year": 2023, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://derma.de/fileadmin/derma/1_derma.de_WebRoot/Leitlinien/091-001l_S3_Lokaltherapie-schwerheilender-chronischer-Wunden_2023-11.pdf", "verification_depth": "full_text", "version_status": "2023 revision", "doi": "", "notes": "Official DDG-hosted guideline PDF. Phototherapy section includes LED, low-level laser, high-intensity laser and filtered infrared; LLLT-specific evidence is separately identified.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: German Society for Wound Healing and Wound Treatment (DGfW) / interdisciplinary S3 guideline panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://derma.de/fileadmin/derma/1_derma.de_WebRoot/Leitlinien/091-001l_S3_Lokaltherapie-schwerheilender-chronischer-Wunden_2023-11.pdf" ] }, { "id": "austria_back", "organization": "Austrian national evidence- and consensus-based low-back guideline panel / federal health ministry", "title": "Leitlinie für das Management akuter, subakuter, chronischer und rezidivierender unspezifischer Kreuzschmerzen 2018: Kurzfassung", "edition_year": 2018, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://www.neuraltherapie.at/wp-content/uploads/2022/05/kurzversion_leitlinie_unspezifischer_kreuzschmerz.pdf", "verification_depth": "full_guideline_short_version", "version_status": "2018 short version", "doi": "", "notes": "Chronic-column recommendation and footnote 15 visually checked in PDF p. 12. The short version calls the intervention laser therapy without specifying device class.", "supporting_urls": [ "https://www.sozialministerium.gv.at/dam/jcr:f475e061-1e96-4d47-9e04-0f504e55834f/Leitlinienreport_Kreuzschmerz_LL_2018.pdf" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Austria", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Austrian national evidence- and consensus-based low-back guideline panel / federal health ministry. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.neuraltherapie.at/wp-content/uploads/2022/05/kurzversion_leitlinie_unspezifischer_kreuzschmerz.pdf" ] }, { "id": "sign_chronicpain", "organization": "Scottish Intercollegiate Guidelines Network (SIGN)", "title": "Management of chronic pain: SIGN 136", "edition_year": 2013, "publication_year": 2013, "document_type": "clinical_practice_guideline", "url": "https://www.sign.ac.uk/assets/sign136.pdf", "verification_depth": "full_text", "version_status": "Historical 2013 text retrieved; not relabelled as 2019", "doi": "", "notes": "The retrieved official PDF explicitly cites December 2013 throughout. A secondary review's 2019 date was not transferred to this source.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United Kingdom (Scotland)", "country_scope_kind": "country", "country_scope_basis": "SIGN is the Scottish Intercollegiate Guidelines Network. Scotland is retained within the United Kingdom label.", "country_scope_source_urls": [ "https://www.sign.ac.uk/assets/sign136.pdf" ] }, { "id": "dutch_shoulder", "organization": "Dutch Orthopaedic Association / multidisciplinary guideline group", "title": "Guideline for diagnosis and treatment of subacromial pain syndrome", "edition_year": 2014, "publication_year": 2014, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC4062801/", "verification_depth": "full_text", "version_status": "2014 edition", "doi": "", "notes": "The laser statement is a Level 3 evidence conclusion about all laser types; not a standalone strong treatment recommendation.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Netherlands", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Dutch Orthopaedic Association / multidisciplinary guideline group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC4062801/" ] }, { "id": "dutch_ankle", "organization": "Dutch multidisciplinary ankle-sprain guideline group (Vuurberg et al.)", "title": "Diagnosis, treatment and prevention of ankle sprains: update of an evidence-based clinical guideline", "edition_year": 2018, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://bjsm.bmj.com/content/52/15/956", "verification_depth": "full_text", "version_status": "2018 update", "doi": "10.1136/bjsports-2017-098106", "notes": "Laser appears within the group of other therapies not advised for acute lateral ankle sprains.", "supporting_urls": [ "https://www.mygcphysio.com.au/wp-content/uploads/2019/08/Ankle-sprains-consensus-statement-2018.pdf" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Netherlands", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Dutch multidisciplinary ankle-sprain guideline group (Vuurberg et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://bjsm.bmj.com/content/52/15/956" ] }, { "id": "chiro_neck", "organization": "Canadian Chiropractic Guideline Development Committee (Bryans et al.)", "title": "Evidence-Based Guidelines for the Chiropractic Treatment of Adults With Neck Pain", "edition_year": 2014, "publication_year": 2014, "document_type": "clinical_practice_guideline", "url": "https://chiro.org/Chronic_Neck/Evidence-Based_Guidelines_for_the_Chiropractic_Treatment.shtml", "verification_depth": "full_text_author_article_reproduction", "version_status": "2014 edition", "doi": "", "notes": "LLLT is listed within a strong multimodal recommendation; the strong rating must not be attributed to laser alone.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Canada", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Canadian Chiropractic Guideline Development Committee (Bryans et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://chiro.org/Chronic_Neck/Evidence-Based_Guidelines_for_the_Chiropractic_Treatment.shtml" ] }, { "id": "japan_aga", "organization": "Japanese Dermatological Association", "title": "Guidelines for the diagnosis and treatment of male-pattern and female-pattern hair loss, 2017 version", "edition_year": 2017, "publication_year": 2018, "document_type": "clinical_practice_guideline", "url": "https://doi.org/10.1111/1346-8138.14470", "verification_depth": "full_text", "version_status": "2017 guideline version; English publication 2018", "doi": "10.1111/1346-8138.14470", "notes": "Published journal article PDF; CQ5 grades LED/low-level laser irradiation B.", "supporting_urls": [ "http://medi-guide.meditool.cn/ymtpdf/FDD6C546-D891-7C2B-370D-AC4DEBCAF202.pdf" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Japan", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Japanese Dermatological Association. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://doi.org/10.1111/1346-8138.14470" ] }, { "id": "spain_aga", "organization": "Spanish Hair Disorders Group of the Spanish Academy of Dermatology and Venereology (GEDA / AEDV)", "title": "Recommendations on the Clinical Management of Androgenetic Alopecia: A Consensus Statement", "edition_year": 2024, "publication_year": 2024, "document_type": "expert_consensus", "url": "https://www.actasdermo.org/en-translated-article-recommendations-on-clinical-articulo-S0001731024000887", "verification_depth": "full_text", "version_status": "2024 consensus", "doi": "", "notes": "General adjunctive use, adolescent use and pregnancy are distinct consensus statements. Expert-level LE 5 / GR D is preserved where reported.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Spain", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Spanish Hair Disorders Group of the Spanish Academy of Dermatology and Venereology (GEDA / AEDV). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.actasdermo.org/en-translated-article-recommendations-on-clinical-articulo-S0001731024000887" ] }, { "id": "china_fibromyalgia", "organization": "Chinese multidisciplinary fibromyalgia guideline development group (Li et al.)", "title": "Guidelines on Treating Fibromyalgia With Nonpharmacological Therapies in China", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12159282/", "verification_depth": "full_text", "version_status": "2025 edition", "doi": "10.1111/jebm.70044", "notes": "Recommendation is explicitly conditional with low certainty and compares with no intervention.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "China", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Chinese multidisciplinary fibromyalgia guideline development group (Li et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC12159282/" ] }, { "id": "acoem_back", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Low Back Disorders", "edition_year": 2020, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/2021/MTUS-Evidence-Based-Update-August/Low-Back-Guideline.pdf", "verification_depth": "full_text", "version_status": "Effective 13 February 2020; California source path dated 2021", "doi": "", "notes": "The complete guideline and 2020 JOEM summary represent the same recommendation family; counted once.", "supporting_urls": [ "https://acoem.org/acoem/media/News-Library/Practice-Guidelines-Non_Invasive-Low-Back-Pain-March-2020-JOEM_1.pdf" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/2021/MTUS-Evidence-Based-Update-August/Low-Back-Guideline.pdf" ] }, { "id": "acoem_cervical", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Cervical and Thoracic Spine Disorders", "edition_year": 2018, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/MTUS-Evidence-Based-Update/Guidelines/ACOEM-Cervical-and-Thoracic-Spine-Guideline.pdf", "verification_depth": "full_text", "version_status": "Effective 17 October 2018; retrieved copyright 2020", "doi": "", "notes": "Edition date is taken from the document header rather than the web directory.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/MTUS-Evidence-Based-Update/Guidelines/ACOEM-Cervical-and-Thoracic-Spine-Guideline.pdf" ] }, { "id": "acoem_shoulder", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Shoulder Disorders", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/2025/MTUS-Evidence-Based-Update-August/Shoulder-Disorders-Guideline.pdf", "verification_depth": "full_text", "version_status": "Effective 14 July 2025", "doi": "", "notes": "Official California MTUS-linked copy. Recommendation, ACOEM evidence grade and confidence are separate fields.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/2025/MTUS-Evidence-Based-Update-August/Shoulder-Disorders-Guideline.pdf" ] }, { "id": "acoem_elbow", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Elbow Disorders", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/2025/MTUS-Evidence-Based-Update-August/Elbow-Disorders-Guideline.pdf", "verification_depth": "full_text", "version_status": "Effective 14 July 2025", "doi": "", "notes": "Newer version used instead of the 2012 guideline quoted by insurer policies.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/2025/MTUS-Evidence-Based-Update-August/Elbow-Disorders-Guideline.pdf" ] }, { "id": "acoem_hand", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Hand, Wrist, and Forearm Disorders", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/2025/MTUS-Evidence-Based-Update-August/Hand-Wrist-Forearm-Disorders-Guideline.pdf", "verification_depth": "full_text", "version_status": "Effective 14 July 2025", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/2025/MTUS-Evidence-Based-Update-August/Hand-Wrist-Forearm-Disorders-Guideline.pdf" ] }, { "id": "acoem_knee", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Knee Disorders", "edition_year": 2019, "publication_year": 2019, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/2020/MTUS-Evidence-Based-Updates-June-2020/ACOEM-Knee-Disorders.pdf", "verification_depth": "full_text", "version_status": "Effective 3 December 2019; California source path dated 2020", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/2020/MTUS-Evidence-Based-Updates-June-2020/ACOEM-Knee-Disorders.pdf" ] }, { "id": "acoem_ankle", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Ankle and Foot Disorders", "edition_year": 2026, "publication_year": 2026, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/2026/MTUS-May/Ankle-Foot-Disorders.pdf", "verification_depth": "full_text", "version_status": "Effective 29 January 2026", "doi": "", "notes": "The chronic-Achilles positive recommendation is restricted to selected patients after other treatments; plantar-fasciitis opening sentence has a modality inconsistency recorded at row level.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/2026/MTUS-May/Ankle-Foot-Disorders.pdf" ] }, { "id": "acoem_hip", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Hip and Groin Disorders", "edition_year": 2026, "publication_year": 2026, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/2026/MTUS-May/Hip-Groin-Disorders.pdf", "verification_depth": "full_text", "version_status": "Effective 29 January 2026", "doi": "", "notes": "", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/2026/MTUS-May/Hip-Groin-Disorders.pdf" ] }, { "id": "acoem_chronicpain", "organization": "American College of Occupational and Environmental Medicine (ACOEM)", "title": "Chronic Pain", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://www.dir.ca.gov/dwc/DWCPropRegs/2026/MTUS/Chronic-Pain.pdf", "verification_depth": "full_text", "version_status": "Effective 22 December 2025; official California source path dated 2026", "doi": "", "notes": "The current linked edition was retrieved; 2024 preliminary material was not counted separately.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Occupational and Environmental Medicine (ACOEM). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dir.ca.gov/dwc/DWCPropRegs/2026/MTUS/Chronic-Pain.pdf" ] }, { "id": "ottawa_ra", "organization": "Ottawa Panel", "title": "Ottawa Panel Evidence-Based Clinical Practice Guidelines for Electrotherapy and Thermotherapy Interventions in the Management of Rheumatoid Arthritis in Adults", "edition_year": 2004, "publication_year": 2004, "document_type": "clinical_practice_guideline", "url": "https://pubmed.ncbi.nlm.nih.gov/15509188/", "verification_depth": "abstract", "version_status": "Historical 2004 evidence base; current status not verified", "doi": "10.1093/ptj/84.11.1016", "notes": "PubMed-indexed abstract retrieved from Europe PMC core metadata. Positive conclusion is explicit; no laser-specific grade inferred from unavailable full text.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Not stated", "country_scope_kind": "not_stated", "country_scope_basis": "The retrieved abstract identifies the Ottawa Panel but does not establish its geographic remit. No country is assigned from the panel name or author affiliations alone.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/15509188/" ] }, { "id": "spain_ra", "organization": "Spanish Society of Rheumatology (SER)", "title": "Guía de Práctica Clínica para el Manejo de Pacientes con Artritis Reumatoide", "edition_year": 2019, "publication_year": 2019, "document_type": "clinical_practice_guideline", "url": "https://www.ser.es/wp-content/uploads/2019/03/Guia-de-Practica-Clinica-para-el-Manejo-de-Pacientes-con-Artritis-Reumatoide.pdf", "verification_depth": "full_text", "version_status": "2019 edition (printed in source)", "doi": "", "notes": "Source discussion is cautiously positive for short-term symptoms; no separate graded laser recommendation was identified.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Spain", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Spanish Society of Rheumatology (SER). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.ser.es/wp-content/uploads/2019/03/Guia-de-Practica-Clinica-para-el-Manejo-de-Pacientes-con-Artritis-Reumatoide.pdf" ] }, { "id": "spain_lymphedema", "organization": "CEFyL / SERMEF (Spain)", "title": "Orientación Diagnóstica y Terapéutica del Linfedema: Guía de Práctica Clínica, 2.ª Edición", "edition_year": 2017, "publication_year": 2017, "document_type": "clinical_practice_guideline", "url": "https://www.capitulodeflebologia.org/wp-content/uploads/2020/06/Guia-linfedema-segunda-edicion-final-2017_439.pdf", "verification_depth": "full_text", "version_status": "2017 second edition", "doi": "", "notes": "Narrative laser section contains a citation to a low-frequency electrotherapy trial. That trial's modality was checked against its abstract and the mismatch is flagged.", "supporting_urls": [ "https://pubmed.ncbi.nlm.nih.gov/22172923/" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Spain", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: CEFyL / SERMEF (Spain). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.capitulodeflebologia.org/wp-content/uploads/2020/06/Guia-linfedema-segunda-edicion-final-2017_439.pdf" ] }, { "id": "korean_tmd", "organization": "Korean medicine TMD guideline development group (Kim et al.)", "title": "Korean Medicine Clinical Practice Guideline Update for Temporomandibular Disorders", "edition_year": 2023, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC10454242/", "verification_depth": "full_text", "version_status": "2023 update", "doi": "10.3390/healthcare11162364", "notes": "Recommendation R15 covers Korean medicine physical therapy including meridian LLLT and TENS; the grade is grouped, not a laser-only grade.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "South Korea", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Korean medicine TMD guideline development group (Kim et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC10454242/" ] }, { "id": "mascc_immunotherapy", "organization": "MASCC/ISOO", "title": "Clinical Practice Statement: management of oral complications of immunotherapy", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_statement", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12433365/", "verification_depth": "full_text", "version_status": "2025 clinical practice statement", "doi": "10.1007/s00520-025-09806-x", "notes": "The statement explicitly notes that efficacy evidence for listed nonpharmacologic treatments in oral irAEs is absent and use is extrapolated from other settings.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: MASCC/ISOO. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC12433365/" ] }, { "id": "mascc_gvhd", "organization": "MASCC/ISOO", "title": "Clinical Practice Statement: Management of oral manifestations of chronic graft-versus-host-disease", "edition_year": 2024, "publication_year": 2024, "document_type": "clinical_practice_statement", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11269426/", "verification_depth": "full_text", "version_status": "2024 clinical practice statement", "doi": "10.1007/s00520-024-08686-x", "notes": "PBM is discussed as an emerging intervention with early evidence and a need for further research.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: MASCC/ISOO. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC11269426/" ] }, { "id": "nccn_mucositis", "organization": "National Comprehensive Cancer Network (NCCN) task force", "title": "NCCN Task Force Report: Prevention and Management of Mucositis in Cancer Care", "edition_year": 2008, "publication_year": 2008, "document_type": "task_force_report", "url": "https://jnccn.org/view/journals/jnccn/6/S1/article-pS-1.xml", "verification_depth": "full_text", "version_status": "Historical 2008 task force report", "doi": "", "notes": "The report's PBM discussion is not treated as a current NCCN Clinical Practice Guidelines recommendation.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: National Comprehensive Cancer Network (NCCN) task force. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://jnccn.org/view/journals/jnccn/6/S1/article-pS-1.xml" ] }, { "id": "npuap_pressure_2014", "organization": "NPUAP / EPUAP / PPPIA", "title": "Prevention and Treatment of Pressure Ulcers: Clinical Practice Guideline", "edition_year": 2014, "publication_year": 2014, "document_type": "clinical_practice_guideline", "url": "https://www.andeal.org/files/files/WoundCare/NPUAP-EPUAP-PPPIA%20CPG%202014.pdf", "verification_depth": "full_text", "version_status": "Historical 2014 edition; later 2019 edition exists", "doi": "", "notes": "Current 2019/2025 laser wording was not verified; preserve as historical rather than current guidance.", "supporting_urls": [ "https://internationalguideline.com/2019" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: NPUAP / EPUAP / PPPIA. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.andeal.org/files/files/WoundCare/NPUAP-EPUAP-PPPIA%20CPG%202014.pdf" ] }, { "id": "vocal_consensus", "organization": "Seven speech-language pathology voice experts (Pontes et al.; Brazil)", "title": "Photobiomodulation on vocal training and rehabilitation: Delphi consensus based on experts", "edition_year": 2025, "publication_year": 2025, "document_type": "expert_consensus_article", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11906107/", "verification_depth": "full_text", "version_status": "2025 Delphi consensus", "doi": "10.1590/2317-1782/e20230356en", "notes": "CVC values measure agreement/content validity among seven experts; they are not clinical efficacy or GRADE certainty ratings. Non-consensus indications are retained.", "supporting_urls": [], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "Brazil", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Seven speech-language pathology voice experts (Pontes et al.; Brazil). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC11906107/" ] }, { "id": "acr_ra_integrative", "organization": "American College of Rheumatology (ACR)", "title": "2022 ACR Guideline for Exercise, Rehabilitation, Diet, and Additional Integrative Interventions for Rheumatoid Arthritis", "edition_year": 2022, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC10947582/", "verification_depth": "licensed_guideline_summary", "version_status": "2022 guideline; publication 2023", "doi": "", "notes": "Authorized Guideline Central summary verifies that unspecified laser therapy appears among thermal modalities. A laser-only or PBM-specific recommendation is not established.", "supporting_urls": [ "https://www.guidelinecentral.com/guideline/2932867/pocket-guide/2932868/" ], "checked_on": "2026-10-15", "added_in": "expansion_02", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Rheumatology (ACR). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC10947582/" ] }, { "id": "turkish_fibro", "organization": "Turkish Society of Physical Medicine and Rehabilitation (TSPMR)", "title": "The Turkish Society of Physical Medicine and Rehabilitation (TSPMR) guideline recommendations for the management of fibromyalgia syndrome", "edition_year": 2019, "publication_year": 2019, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC6706830/", "verification_depth": "full_text", "version_status": "2019 guideline", "doi": "10.5606/tftrd.2019.4815", "notes": "The weak positive recommendation is for a group of physical/electrotherapeutic modalities as part of care; the LLLT-specific discussion remains controversial.", "supporting_urls": [ "https://ftrdergisi.com/pdf/f6118de3-f656-440d-95f2-50c620149951/articles/tftrd.2019.4815/pdf_4131.pdf" ], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "Türkiye", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Turkish Society of Physical Medicine and Rehabilitation (TSPMR). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC6706830/" ] }, { "id": "aapd_lasers", "organization": "American Academy of Pediatric Dentistry (AAPD)", "title": "Policy on the Use of Lasers for Pediatric Dental Patients", "edition_year": 2022, "publication_year": 2025, "document_type": "policy_statement", "url": "https://www.aapd.org/media/policies_guidelines/p_lasersuse.pdf", "verification_depth": "full_text", "version_status": "Latest revision 2022; retrieved in the 2025 Reference Manual", "doi": "", "notes": "Society policy with narrative PBM applications. The general laser policy is not a formal PBM-specific graded clinical practice guideline.", "supporting_urls": [ "https://www.aapd.org/research/oral-health-policies--recommendations/use-of-lasers-for-pediatric-dental-patients/" ], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American Academy of Pediatric Dentistry (AAPD). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.aapd.org/media/policies_guidelines/p_lasersuse.pdf" ] }, { "id": "afsos_mucites", "organization": "Association Francophone des Soins Oncologiques de Support (AFSOS)", "title": "Mucites et candidoses", "edition_year": 2015, "publication_year": 2015, "document_type": "clinical_practice_guideline", "url": "https://www.afsos.org/wp-content/uploads/2016/09/Mucites_version_finale_AFSOS-2.pdf", "verification_depth": "full_text", "version_status": "Validated 11 December 2015", "doi": "", "notes": "Slide 13 is explicitly an informational synthesis reproducing MASCC 2014. The local snapshot filename is historical extraction naming; the document's printed date is 2015.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "France", "country_scope_kind": "country", "country_scope_basis": "AFSOS is the France-based Association Francophone des Soins Oncologiques de Support. France identifies the issuing body; Francophone does not mean France-only clinical applicability.", "country_scope_source_urls": [ "https://www.afsos.org/wp-content/uploads/2016/09/Mucites_version_finale_AFSOS-2.pdf", "https://www.afsos.org/congres-formations/congres/" ] }, { "id": "afsos_oral_rt", "organization": "Association Francophone des Soins Oncologiques de Support (AFSOS)", "title": "Toxicités bucco-dentaires et cancer (radiothérapie)", "edition_year": 2020, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://www.afsos.org/wp-content/uploads/2020/11/Toxicit%C3%A9s-bucco-dentaires-et-cancer-rth_AFSOS.pdf", "verification_depth": "full_text", "version_status": "Validated 9 October 2020", "doi": "", "notes": "Refers to the AFSOS mucositis reference for low-energy laser; not independent trial evidence.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "France", "country_scope_kind": "country", "country_scope_basis": "AFSOS is the France-based Association Francophone des Soins Oncologiques de Support. France identifies the issuing body; Francophone does not mean France-only clinical applicability.", "country_scope_source_urls": [ "https://www.afsos.org/wp-content/uploads/2020/11/Toxicit%C3%A9s-bucco-dentaires-et-cancer-rth_AFSOS.pdf", "https://www.afsos.org/congres-formations/congres/" ] }, { "id": "afsos_taste", "organization": "Association Francophone des Soins Oncologiques de Support (AFSOS)", "title": "Prise en charge des modifications de la capacité olfactive, gustative et/ou de la déglutition dans les cancers ORL", "edition_year": 2016, "publication_year": 2017, "document_type": "clinical_practice_guideline", "url": "https://www.afsos.org/wp-content/uploads/2017/03/2017-03-02_Ref_AFSOS_gout_texture_odeur_orl.pdf", "verification_depth": "full_text", "version_status": "Validated 15 December 2016; hosted March 2017", "doi": "", "notes": "Edition date follows the printed validation date; the hosting path is not used as the guideline edition.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "France", "country_scope_kind": "country", "country_scope_basis": "AFSOS is the France-based Association Francophone des Soins Oncologiques de Support. France identifies the issuing body; Francophone does not mean France-only clinical applicability.", "country_scope_source_urls": [ "https://www.afsos.org/wp-content/uploads/2017/03/2017-03-02_Ref_AFSOS_gout_texture_odeur_orl.pdf", "https://www.afsos.org/congres-formations/congres/" ] }, { "id": "afsos_skin", "organization": "Association Francophone des Soins Oncologiques de Support (AFSOS)", "title": "Toxicité cutanée radioinduite", "edition_year": 2014, "publication_year": 2014, "document_type": "clinical_practice_guideline", "url": "https://www.afsos.org/wp-content/uploads/2016/09/2014-12-12-_J2R_tox_cutanee_radioinduite_VF.pdf", "verification_depth": "full_text", "version_status": "Validated 12 December 2014; later recommendations from other organizations are available", "doi": "", "notes": "Low-energy laser is described as under evaluation. Pulsed-dye laser for telangiectasia is a separate intervention and is not treated as PBM.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "France", "country_scope_kind": "country", "country_scope_basis": "AFSOS is the France-based Association Francophone des Soins Oncologiques de Support. France identifies the issuing body; Francophone does not mean France-only clinical applicability.", "country_scope_source_urls": [ "https://www.afsos.org/wp-content/uploads/2016/09/2014-12-12-_J2R_tox_cutanee_radioinduite_VF.pdf", "https://www.afsos.org/congres-formations/congres/" ] }, { "id": "estro_rd", "organization": "ESTRO Radiation Therapists Committee", "title": "Practical recommendations for the management of radiodermatitis: on behalf of the ESTRO RTT committee", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11954187/", "verification_depth": "full_text", "version_status": "2025 recommendations", "doi": "10.1186/s13014-025-02624-9", "notes": "The recommendation concerns prevention of higher-grade radiodermatitis; key supporting PBM studies concern breast irradiation.", "supporting_urls": [ "https://link.springer.com/article/10.1186/s13014-025-02624-9" ], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "Europe", "country_scope_kind": "region", "country_scope_basis": "Recommendations are issued on behalf of the European Society for Radiotherapy and Oncology RTT Committee by an international writing group. Europe denotes the issuing society, not an exclusive clinical-use boundary.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC11954187/" ] }, { "id": "fdi_lasers", "organization": "FDI World Dental Federation", "title": "Lasers in Dentistry", "edition_year": 2024, "publication_year": 2024, "document_type": "policy_statement", "url": "https://fdiworlddental.org/lasers-dentistry", "verification_depth": "full_text", "version_status": "Adopted September 2024, Istanbul", "doi": "", "notes": "Policy scope is laser education, training and safety. PBM wound-healing benefit appears in the context paragraph, without a condition-specific treatment grade.", "supporting_urls": [ "https://www.fdiworlddental.org/sites/default/files/2024-11/DPS4-Lasers-in-Dentistry.pdf" ], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: FDI World Dental Federation. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://fdiworlddental.org/lasers-dentistry" ] }, { "id": "dog_amd", "organization": "Deutsche Ophthalmologische Gesellschaft (DOG); Retinologische Gesellschaft; Berufsverband der Augenärzte Deutschlands (BVA)", "title": "Photobiomodulation bei AMD", "edition_year": 2025, "publication_year": 2025, "document_type": "position_paper", "url": "https://www.augeninfo.de/stellungnahmen/Photobiomodulation_bei_AMD.pdf", "verification_depth": "full_text", "version_status": "Statement dated 4 July 2025", "doi": "10.1007/s00347-025-02303-w", "notes": "States that efficacy is unproven and PBM should currently be used only in clinical studies. This clinical position is distinct from regulatory authorization.", "supporting_urls": [ "https://dog.org/fuer-aerzte/leitlinien-stellungnahmen-empfehlungen/diabetes-glaskoerper-netzhaut/stellungnahmen-diabetes-glaskoerper-netzhaut/photobiomodulation-amd" ], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Deutsche Ophthalmologische Gesellschaft (DOG); Retinologische Gesellschaft; Berufsverband der Augenärzte Deutschlands (BVA). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.augeninfo.de/stellungnahmen/Photobiomodulation_bei_AMD.pdf" ] }, { "id": "scor_rd", "organization": "Society and College of Radiographers (SCoR)", "title": "Radiation Dermatitis Guidelines for Radiotherapy Healthcare Professionals", "edition_year": 2020, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://www.sor.org/getmedia/6cc80174-4478-4cd2-b501-35b41aae820d/2020_version_4_final_practice_guideline_radiotherapy_skin_care_llv1.pdf", "verification_depth": "full_text", "version_status": "Second revised edition April 2020; stated review date 2025; newer edition not verified", "doi": "", "notes": "The body explicitly does not recommend PBMT at that time, citing uncertainty about modern hypofractionation and long-term outcomes. Later ESTRO 2025 guidance differs.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "United Kingdom", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Society and College of Radiographers (SCoR). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.sor.org/getmedia/6cc80174-4478-4cd2-b501-35b41aae820d/2020_version_4_final_practice_guideline_radiotherapy_skin_care_llv1.pdf" ] }, { "id": "mexico_rd", "organization": "Sociedad Mexicana de Radioterapia (SOMERA) expert panel", "title": "Mexican radiationdermatitis management consensus", "edition_year": 2022, "publication_year": 2022, "document_type": "society_consensus", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC9746638/", "verification_depth": "full_text", "version_status": "2022 consensus", "doi": "10.5603/RPOR.a2022.0101", "notes": "PBMT is an emerging approach; more long-term research is requested before a prophylactic recommendation.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "Mexico", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Sociedad Mexicana de Radioterapia (SOMERA) expert panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC9746638/" ] }, { "id": "eapd_mih", "organization": "European Academy of Paediatric Dentistry (EAPD)", "title": "Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated EAPD policy document", "edition_year": 2021, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC8926988/", "verification_depth": "full_text", "version_status": "2021 update; online 2021; journal volume 2022", "doi": "10.1007/s40368-021-00668-5", "notes": "Table 10 conditionally allows a group including laser for hypersensitivity, with low certainty. The narrative is more cautious; neither wording is converted into a laser-only recommendation.", "supporting_urls": [ "https://www.eapd.eu/uploads/files/MIH_Best_Practice.pdf" ], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "Europe", "country_scope_kind": "region", "country_scope_basis": "Issuing organization or panel identified in the source: European Academy of Paediatric Dentistry (EAPD). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC8926988/" ] }, { "id": "eb_oral", "organization": "International EB oral-health guideline group; DEBRA International-supported", "title": "Clinical practice guidelines: Oral health care for children and adults living with epidermolysis bullosa", "edition_year": 2020, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC7756753/", "verification_depth": "full_text", "version_status": "2020 update of the 2012 oral-health guideline", "doi": "10.1111/scd.12511", "notes": "The laser discussion includes a seven-patient pilot combining cord-blood platelet gel and LLLT; isolated PBM benefit cannot be inferred.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: International EB oral-health guideline group; DEBRA International-supported. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC7756753/" ] }, { "id": "s2k_aphthae", "organization": "AKOPOM; DGMKG; DGZMK with participating German medical societies", "title": "Diagnostik und Therapieoptionen von Aphthen und aphthoiden Läsionen der Mund- und Rachenschleimhaut", "edition_year": 2023, "publication_year": 2023, "document_type": "clinical_practice_guideline", "url": "https://register.awmf.org/assets/guidelines/007-101l_S2k_Aphthen_aphthoide-L%C3%A4sionen_2023-06_02.pdf", "verification_depth": "full_text", "version_status": "S2k long version April 2023; valid until April 2028", "doi": "", "notes": "Mixed laser types are discussed; no standardized laser protocol is identified. The treatment-option wording is not presented as a standalone graded PBM recommendation.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: AKOPOM; DGMKG; DGZMK with participating German medical societies. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://register.awmf.org/assets/guidelines/007-101l_S2k_Aphthen_aphthoide-L%C3%A4sionen_2023-06_02.pdf" ] }, { "id": "ras_india", "organization": "Indian multidisciplinary expert consensus panel (Bhargava et al.)", "title": "Management of Recurrent Aphthous Stomatitis: An Indian Expert Consensus", "edition_year": 2023, "publication_year": 2023, "document_type": "expert_consensus_article", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC10447672/", "verification_depth": "full_text", "version_status": "2023 expert consensus", "doi": "10.1007/s12070-023-03708-2", "notes": "Contains a favorable narrative on mixed laser modalities, including diode low-level mode; no laser-specific formal recommendation grade was verified.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "India", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Indian multidisciplinary expert consensus panel (Bhargava et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC10447672/" ] }, { "id": "aao_tinnitus_2026", "organization": "American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF)", "title": "Clinical Practice Guideline: Tinnitus Update — official research agenda", "edition_year": 2026, "publication_year": 2026, "document_type": "guideline_update_note", "url": "https://www.entnet.org/resource/cpg-tinnitus-update/", "verification_depth": "official_update_note_only", "version_status": "2026 update; official research-agenda page published 9 October 2026", "doi": "10.1002/ohn.70417", "notes": "The accessible official research agenda explicitly names low-level laser therapy; the complete therapeutic recommendation was not retrieved. Research-priority status is not a recommendation to treat.", "supporting_urls": [ "https://www.entnet.org/quality-practice/quality-products/clinical-practice-guidelines/cpg-tinnitus-update/" ], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.entnet.org/resource/cpg-tinnitus-update/" ] }, { "id": "dentine_mea", "organization": "Middle East and Africa dental expert advisory panel (Cekici et al.)", "title": "Evidence-based recommendations for diagnosing and managing dentine hypersensitivity in clinical practice: insights from the Middle East and Africa", "edition_year": 2025, "publication_year": 2025, "document_type": "expert_consensus_article", "url": "https://www.frontiersin.org/journals/oral-health/articles/10.3389/froh.2025.1663984/full", "verification_depth": "full_text", "version_status": "2025 consensus; advisory meeting June 2024", "doi": "10.3389/froh.2025.1663984", "notes": "Mixed high/low-power laser evidence; source reports AI in an evidence-grade/level column. Sponsored advisory process is disclosed by the paper; no laser-only PBM GRADE rating is inferred.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "Middle East & Africa", "country_scope_kind": "region", "country_scope_basis": "The title and expert panel explicitly identify the Middle East and Africa as the regional context.", "country_scope_source_urls": [ "https://www.frontiersin.org/journals/oral-health/articles/10.3389/froh.2025.1663984/full" ] }, { "id": "isp_dentine", "organization": "Indian Society of Periodontology (ISP)", "title": "ISP Good Clinical Practice Recommendations for the management of Dentin Hypersensitivity", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC9362809/", "verification_depth": "full_text", "version_status": "2022 good clinical practice recommendations", "doi": "10.4103/jisp.jisp_233_22", "notes": "Provides practical laser treatment guidance while acknowledging lack of a gold-standard parameter protocol; discusses both low-power diode and high-power approaches.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "India", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Indian Society of Periodontology (ISP). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC9362809/" ] }, { "id": "senorif_breast", "organization": "SENORIF breast-cancer diagnostic and therapeutic reference group; hosted by Gustave Roussy", "title": "Référentiel diagnostique et thérapeutique SEIN — SENORIF", "edition_year": 2026, "publication_year": 2026, "document_type": "clinical_practice_guideline", "url": "https://www.gustaveroussy.fr/sites/default/files/documents/2026-10/referenciel-senorif-202609.pdf", "verification_depth": "full_text", "version_status": "September 2026 edition", "doi": "", "notes": "Regional breast-cancer reference. Table 27 explicitly names PBM among physical therapies not advised for vulvovaginal dryness; the recommendation is not generalized to other indications.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_03", "country_scope": "France", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: SENORIF breast-cancer diagnostic and therapeutic reference group; hosted by Gustave Roussy. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.gustaveroussy.fr/sites/default/files/documents/2026-10/referenciel-senorif-202609.pdf" ] }, { "id": "oarsi_2019", "organization": "Osteoarthritis Research Society International (OARSI)", "title": "OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis", "edition_year": 2019, "publication_year": 2019, "document_type": "clinical_practice_guideline", "url": "https://www.oarsijournal.com/article/S1063-4584(19)31116-1/fulltext", "verification_depth": "full_text_and_official_supplements", "version_status": "2019 guideline", "doi": "10.1016/j.joca.2019.06.011", "notes": "Official Supplementary Table 5 differentiates knee-OA subgroups; Table 8 strongly advises against laser for hip/polyarticular OA and against laser acupuncture. Level 3 has 40–59% in favor and is not treated as positive consensus. The recommendation tables do not specify a low-level-only device class.", "supporting_urls": [ "https://www.esceo.org/sites/esceo/files/pdf/Bannuru_O%26C_OARSIguidelines_2019.pdf", "https://ars.els-cdn.com/content/image/1-s2.0-S1063458419311161-mmc5.docx", "https://ars.els-cdn.com/content/image/1-s2.0-S1063458419311161-mmc8.docx" ], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: Osteoarthritis Research Society International (OARSI). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.oarsijournal.com/article/S1063-4584(19)31116-1/fulltext" ] }, { "id": "australia_wound_2021", "organization": "Diabetes Feet Australia / Australian evidence-based diabetes-related foot disease guideline panel", "title": "Australian guideline on wound healing interventions to enhance healing of foot ulcers: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease", "edition_year": 2021, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC9131573/", "verification_depth": "full_text", "version_status": "2021 guideline; journal publication 2022", "doi": "10.1186/s13047-022-00544-5", "notes": "Adapted from IWGDF 2019; physical-therapy recommendation includes laser in the clinical question/rationale. The Australian panel downgraded the grouped recommendation from strong to weak.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Australia", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Diabetes Feet Australia / Australian evidence-based diabetes-related foot disease guideline panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC9131573/" ] }, { "id": "china_mronj_2024", "organization": "Chinese expert panel on medication-related osteonecrosis of the jaw (Ruan et al.)", "title": "Chinese expert consensus on the diagnosis and clinical management of medication-related osteonecrosis of the jaw", "edition_year": 2024, "publication_year": 2024, "document_type": "expert_consensus_article", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11621599/", "verification_depth": "full_text", "version_status": "2024 expert consensus", "doi": "10.1016/j.jbo.2024.100650", "notes": "LLLT is discussed as a promising adjunct, with explicit acknowledgment of a lack of high-quality studies. Combined-treatment findings are not isolated PBM effects.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "China", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Chinese expert panel on medication-related osteonecrosis of the jaw (Ruan et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC11621599/" ] }, { "id": "italy_mronj_2023", "organization": "Società Italiana di Patologia e Medicina Orale (SIPMO); Società Italiana di Chirurgia Maxillo-Facciale (SICMF)", "title": "Italian position paper (SIPMO-SICMF) on medication-related osteonecrosis of the jaw (MRONJ)", "edition_year": 2023, "publication_year": 2024, "document_type": "position_paper", "url": "https://doi.org/10.1111/odi.14887", "verification_depth": "full_text", "version_status": "2023 position update; published 2024", "doi": "10.1111/odi.14887", "notes": "Table 7(c) includes LLLT/PBM as an adjunct in nonsurgical palliative management when surgery is contraindicated or declined. Laser-assisted bone surgery in other table rows is a different intervention.", "supporting_urls": [ "https://www.research.unipd.it/retrieve/bc41f2e8-15f5-484d-b044-0baf04612b96/Oral%20Diseases%20-%202024%20-%20Bedogni%20-%20Italian%20position%20paper%20SIPMO%E2%80%90SICMF%20on%20medication%E2%80%90related%20osteonecrosis%20of%20the%20jaw%20MRONJ.pdf" ], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Italy", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Società Italiana di Patologia e Medicina Orale (SIPMO); Società Italiana di Chirurgia Maxillo-Facciale (SICMF). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://doi.org/10.1111/odi.14887" ] }, { "id": "argentina_oa_2010", "organization": "Sociedad Argentina de Reumatología", "title": "Guías Argentinas de Práctica Clínica para el Diagnóstico y el Tratamiento de la Osteoartritis", "edition_year": 2010, "publication_year": 2010, "document_type": "clinical_practice_guideline", "url": "https://reumatologia.org.ar/recursos/guia_osteoartritis_2010.pdf", "verification_depth": "full_text", "version_status": "Historical 2010 edition; current validity not established", "doi": "", "notes": "Narrative physical-modality statements on knee and hand OA; separate laser recommendation grades were not verified.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Argentina", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Sociedad Argentina de Reumatología. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://reumatologia.org.ar/recursos/guia_osteoartritis_2010.pdf" ] }, { "id": "imss_knee_2014", "organization": "Instituto Mexicano del Seguro Social (IMSS)", "title": "Prevención, Diagnóstico y Tratamiento de Rehabilitación en el Paciente Adulto con Osteoartrosis de Rodilla en los Tres Niveles de Atención", "edition_year": 2014, "publication_year": 2014, "document_type": "clinical_practice_guideline", "url": "https://www.imss.gob.mx/sites/all/statics/guiasclinicas/726GER.pdf", "verification_depth": "full_text", "version_status": "IMSS-726-14; published 25 September 2014", "doi": "", "notes": "Laser section summarizes mixed evidence and attributes the short-term grade-D statement to the Australian 2009 guideline. That attribution is retained; not presented as an independent evidence vote.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Mexico", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Instituto Mexicano del Seguro Social (IMSS). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.imss.gob.mx/sites/all/statics/guiasclinicas/726GER.pdf" ] }, { "id": "aapd_chemo_2022", "organization": "American Academy of Pediatric Dentistry (AAPD)", "title": "Dental Management of Pediatric Patients Receiving Immunosuppressive Therapy and/or Head and Neck Radiation", "edition_year": 2022, "publication_year": 2025, "document_type": "clinical_practice_guideline", "url": "https://www.aapd.org/globalassets/media/policies_guidelines/bp_chemo.pdf", "verification_depth": "full_text", "version_status": "Latest revision 2022; retrieved in 2025 Reference Manual", "doi": "", "notes": "Best-practice document, distinct from AAPD's general laser policy. Cites MASCC/ISOO and pediatric studies; no standalone PBM-specific numeric grade is supplied.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American Academy of Pediatric Dentistry (AAPD). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.aapd.org/globalassets/media/policies_guidelines/bp_chemo.pdf" ] }, { "id": "southafrica_cmp_2023", "organization": "South African primary-health-care multidisciplinary Delphi research panel (Ernstzen et al.)", "title": "Clinical recommendations for chronic musculoskeletal pain in South African primary health care", "edition_year": 2023, "publication_year": 2023, "document_type": "expert_consensus_article", "url": "https://phcfm.org/index.php/phcfm/article/view/3929/6206", "verification_depth": "full_text", "version_status": "2023 contextualization consensus", "doi": "10.4102/phcfm.v15i1.3929", "notes": "The LLLT passage concerns uncertainty about local applicability and feasibility, not proof of clinical ineffectiveness. Underlying guideline recommendations are being contextualized.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "South Africa", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: South African primary-health-care multidisciplinary Delphi research panel (Ernstzen et al.). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://phcfm.org/index.php/phcfm/article/view/3929/6206" ] }, { "id": "singapore_knee_2026", "organization": "Agency for Care Effectiveness (ACE), Ministry of Health Singapore", "title": "Management of knee osteoarthritis – a joint effort with patients", "edition_year": 2026, "publication_year": 2026, "document_type": "clinical_practice_guideline", "url": "https://www.ace-hta.gov.sg/healthcare-professionals/acg/management-of-knee-osteoarthritis---a-joint-effort-with-patients-acg/", "verification_depth": "full_text", "version_status": "ACE Clinical Guideline; updated 29 July 2026", "doi": "", "notes": "Contains a grouped caution about electrotherapies including unspecified laser. A PBM-only graded recommendation is not established.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Singapore", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Agency for Care Effectiveness (ACE), Ministry of Health Singapore. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.ace-hta.gov.sg/healthcare-professionals/acg/management-of-knee-osteoarthritis---a-joint-effort-with-patients-acg/" ] }, { "id": "lympho_framework_2006", "organization": "Lymphoedema Framework international consensus working group", "title": "Best Practice for the Management of Lymphoedema: International Consensus", "edition_year": 2006, "publication_year": 2006, "document_type": "society_consensus", "url": "https://www.lympho.org/uploads/files/files/Best_practice.pdf", "verification_depth": "full_text", "version_status": "Historical 2006 consensus; not a current-version claim", "doi": "", "notes": "A cautious narrative statement of potential benefit, with further research requested; distinct from ISL 2020/2023.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "Issuing organization or panel identified in the source: Lymphoedema Framework international consensus working group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.lympho.org/uploads/files/files/Best_practice.pdf" ] }, { "id": "ptsl_mucositis_2025", "organization": "Polish Society for Laser Dentistry (PTSL)", "title": "Laser therapy for the management of oral mucositis: An umbrella review – official recommendations of the Polish Society for Laser Dentistry", "edition_year": 2025, "publication_year": 2025, "document_type": "society_consensus", "url": "https://dmp.umw.edu.pl/en/article/2025/62/6/1157/", "verification_depth": "full_text", "version_status": "2025 original; author-translated Polish reprint 2026", "doi": "10.17219/dmp/213958", "notes": "Own clinical recommendations are distinguished from its summary of other organizations. Its characterization of HTW 2022 as supporting implementation conflicts with HTW's primary guidance; see Source issues. Original and translated reprint counted once.", "supporting_urls": [ "https://dmp.umw.edu.pl/pdf/2025/62/6/1157.pdf", "https://implantologiastomatologiczna.pl/wp-content/uploads/2026/04/Laseroterapia-%E2%80%93-rekomendacje-PTSL.pdf" ], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Poland", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Polish Society for Laser Dentistry (PTSL). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://dmp.umw.edu.pl/en/article/2025/62/6/1157/" ] }, { "id": "htw_mucositis_2022", "organization": "Health Technology Wales (HTW)", "title": "HTW Guidance 044: Photobiomodulation for the prevention or treatment of oral mucositis in people receiving cancer treatment", "edition_year": 2022, "publication_year": 2022, "document_type": "procedure_guidance", "url": "https://healthtechnology.wales/wp-content/uploads/2022/05/GUI044-photobiomodulation-FINAL-english.pdf", "verification_depth": "full_text", "version_status": "October 2022 guidance; report v2 hosted March 2023", "doi": "", "notes": "Routine adoption is not supported despite clinical laser-PBM benefit, because of the Welsh NHS cost-effectiveness analysis and staffing costs. LED evidence is separately insufficient. The final guidance is used instead of the preliminary topic report.", "supporting_urls": [ "https://healthtechnology.wales/reports-guidance/photobiomodulation/", "https://healthtechnology.wales/wp-content/uploads/2023/03/EAR044-PBM-FINAL-v2.pdf" ], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "United Kingdom (Wales)", "country_scope_kind": "country", "country_scope_basis": "Health Technology Wales issues guidance for Wales; Wales is retained within the United Kingdom label. The adoption decision is specific to NHS Wales.", "country_scope_source_urls": [ "https://healthtechnology.wales/wp-content/uploads/2022/05/GUI044-photobiomodulation-FINAL-english.pdf" ] }, { "id": "russia_lip_2024", "organization": "Russian oncology/head-and-neck professional associations; approved by the Russian Ministry of Health scientific-practical council", "title": "Злокачественные новообразования губы / Malignant neoplasms of the lip", "edition_year": 2024, "publication_year": 2024, "document_type": "clinical_practice_guideline", "url": "https://diseases.medelement.com/disease/%D0%B7%D0%BB%D0%BE%D0%BA%D0%B0%D1%87%D0%B5%D1%81%D1%82%D0%B2%D0%B5%D0%BD%D0%BD%D1%8B%D0%B5-%D0%BD%D0%BE%D0%B2%D0%BE%D0%BE%D0%B1%D1%80%D0%B0%D0%B7%D0%BE%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F-%D0%B3%D1%83%D0%B1%D1%8B-%D0%BA%D1%80-%D1%80%D1%84-2024/18458", "verification_depth": "full_text_guideline_reproduction", "version_status": "2024 national guideline; ID 553_2; review due by 2026", "doi": "", "notes": "Read from complete guideline reproduction. Bibliographic ID, year and issuing bodies verified. Grades are the Russian source's own system. The document also mentions intravenous laser blood irradiation; that distinct intervention is excluded from PBM rows.", "supporting_urls": [ "https://medvestnik.ru/cr/553_2.html", "https://www.consultant.ru/document/cons_doc_LAW_494568/8efd5f17af55cb35a770f73937590c642437b7eb/" ], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Russia", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Russian oncology/head-and-neck professional associations; approved by the Russian Ministry of Health scientific-practical council. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://diseases.medelement.com/disease/%D0%B7%D0%BB%D0%BE%D0%BA%D0%B0%D1%87%D0%B5%D1%81%D1%82%D0%B2%D0%B5%D0%BD%D0%BD%D1%8B%D0%B5-%D0%BD%D0%BE%D0%B2%D0%BE%D0%BE%D0%B1%D1%80%D0%B0%D0%B7%D0%BE%D0%B2%D0%B0%D0%BD%D0%B8%D1%8F-%D0%B3%D1%83%D0%B1%D1%8B-%D0%BA%D1%80-%D1%80%D1%84-2024/18458" ] }, { "id": "racgp_oa_2009", "organization": "Royal Australian College of General Practitioners (RACGP)", "title": "Guideline for the non-surgical management of hip and knee osteoarthritis", "edition_year": 2009, "publication_year": 2009, "document_type": "clinical_practice_guideline", "url": "https://www.racgp.org.au/FSDEDEV/media/documents/Clinical%20Resources/Guidelines/Joint%20replacement/Guideline-for-the-non-surgical-management-of-hip-and-knee-osteoarthritis.pdf", "verification_depth": "full_text", "version_status": "Historical 2009 edition; superseded by 2018 second edition", "doi": "", "notes": "Weak positive grade D in 2009 contrasts with the later 2018 recommendation against already in the collection. The historical recommendation must not be presented as the current RACGP position.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Australia", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Royal Australian College of General Practitioners (RACGP). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.racgp.org.au/FSDEDEV/media/documents/Clinical%20Resources/Guidelines/Joint%20replacement/Guideline-for-the-non-surgical-management-of-hip-and-knee-osteoarthritis.pdf" ] }, { "id": "ecuador_lbp_2016", "organization": "Ministerio de Salud Pública del Ecuador", "title": "Dolor lumbar: Guía de Práctica Clínica", "edition_year": 2016, "publication_year": 2016, "document_type": "clinical_practice_guideline", "url": "https://www.salud.gob.ec/wp-content/uploads/2017/02/GU%C3%8DA-DOLOR-LUMBAR_16012017.pdf", "verification_depth": "full_text", "version_status": "Cover dated 2016; hosted January/February 2017", "doi": "", "notes": "Bibliographic imprint cites 2015 while the cover says 2016. Laser class is unspecified and the glossary describes heat generation; a PBM-specific recommendation is not inferred.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Ecuador", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Ministerio de Salud Pública del Ecuador. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.salud.gob.ec/wp-content/uploads/2017/02/GU%C3%8DA-DOLOR-LUMBAR_16012017.pdf" ] }, { "id": "rnao_pressure_2016", "organization": "Registered Nurses’ Association of Ontario (RNAO)", "title": "Assessment and Management of Pressure Injuries for the Interprofessional Team, Third Edition", "edition_year": 2016, "publication_year": 2016, "document_type": "clinical_practice_guideline", "url": "https://rnao.ca/media/10209/download", "verification_depth": "historical_recommendation_in_2024_official_comparison", "version_status": "Historical 2016 third edition; superseded by fourth edition 2024", "doi": "", "notes": "The 2016 laser wording is explicitly reproduced in the 2024 official comparison document, p. 14. This is not classified as a 2024 laser recommendation.", "supporting_urls": [], "checked_on": "2026-10-16", "added_in": "expansion_04", "country_scope": "Canada", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Registered Nurses’ Association of Ontario (RNAO). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://rnao.ca/media/10209/download" ] }, { "id": "stm_oa_2019", "organization": "Society for Translational Medicine expert panel", "title": "Society for translational medicine-expert consensus on the treatment of osteoarthritis", "edition_year": 2019, "publication_year": 2019, "document_type": "expert_consensus_article", "url": "https://aoj.amegroups.org/article/view/5605/html", "verification_depth": "full_text", "version_status": "December 2019 issue; publisher page created January 2020", "doi": "10.21037/aoj.2019.12.13", "supporting_urls": [], "notes": "PBMT section is headed limitedly recommended, but its rationale also reports conflicting clinical evidence and calls for better trials. Publisher citation dates and issue identify 2019 despite 2020 page-creation/BibTeX metadata.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "International", "country_scope_kind": "international", "country_scope_basis": "STM describes itself as a global non-profit organization established in Hong Kong. The society scope is used rather than the location of its headquarters or a corresponding author.", "country_scope_source_urls": [ "https://aoj.amegroups.org/article/view/5605/html", "https://www.thestm.org/" ] }, { "id": "eviq_rd_2025", "organization": "Cancer Institute NSW / eviQ", "title": "Radiation-induced dermatitis (ID 1477, version 7)", "edition_year": 2025, "publication_year": 2025, "document_type": "clinical_practice_statement", "url": "https://www.eviq.org.au/clinical-resources/radiation-oncology/side-effect-and-toxicity-management/1477-radiation-induced-dermatitis", "verification_depth": "full_text", "version_status": "Version 7; change log 22 September 2025; review due June 2029", "doi": "", "supporting_urls": [], "notes": "Issued clinical supportive-care resource, distinguished from a separately graded CPG. The prevention section describes PBMT as emerging and cites MASCC and a meta-analysis; it does not supply a separate eviQ PBM grade. Hair-removal laser advice is unrelated and excluded.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Australia", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Cancer Institute NSW / eviQ. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.eviq.org.au/clinical-resources/radiation-oncology/side-effect-and-toxicity-management/1477-radiation-induced-dermatitis" ] }, { "id": "aan_pdn_2011", "organization": "American Academy of Neurology / AANEM / AAPM&R", "title": "Evidence-based guideline: Treatment of painful diabetic neuropathy", "edition_year": 2011, "publication_year": 2011, "document_type": "clinical_practice_guideline", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC3100130/", "verification_depth": "full_text", "version_status": "Historical 2011 guideline; publisher marks RETIRED", "doi": "10.1212/WNL.0b013e3182166ebe", "supporting_urls": [ "https://www.neurology.org/doi/pdfdirect/10.1212/WNL.0b013e3182166ebe", "https://www.aan.com/Guidelines/Home/GuidelineDetail/1037" ], "notes": "Level B is a recommendation against low-intensity laser. The 2022 update focuses on oral/topical treatments and must not be presented as a new appraisal or reaffirmation of laser.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American Academy of Neurology / AANEM / AAPM&R. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC3100130/" ] }, { "id": "egypt_aga_2025", "organization": "Egyptian national expert panel, coordinated by Venus Research Center", "title": "Consensus Recommendations for the Management of Androgenetic Alopecia in Egypt: A Modified Delphi Study", "edition_year": 2025, "publication_year": 2025, "document_type": "expert_consensus_article", "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12533493/", "verification_depth": "full_text", "version_status": "2025 document", "doi": "10.2147/CCID.S556881", "supporting_urls": [ "https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12533493/fullTextXML" ], "notes": "Statement 17 is a supportive clinical-effects statement with 95% panel agreement. Agreement is not a GRADE certainty rating or a treatment effect estimate. Regulatory and mechanistic claims in the discussion are not generalized here.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Egypt", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Egyptian national expert panel, coordinated by Venus Research Center. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC12533493/" ] }, { "id": "canada_aga_2025", "organization": "Canadian androgenetic alopecia expert panel (11 physicians)", "title": "A Canadian Consensus on Androgenetic Alopecia: Approach and Management", "edition_year": 2025, "publication_year": 2025, "document_type": "expert_consensus_article", "url": "https://pubmed.ncbi.nlm.nih.gov/40986632/", "verification_depth": "abstract", "version_status": "2025 document", "doi": "10.1177/12034754251368849", "supporting_urls": [ "https://journals.sagepub.com/doi/10.1177/12034754251368849" ], "notes": "The primary indexed abstract places LLLT among recommended interventions with near consensus. Exact vote, dose, device and full-text qualifications remain unverified. A national expert consensus is not automatically a national health-authority or society CPG.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Canada", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Canadian androgenetic alopecia expert panel (11 physicians). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://pubmed.ncbi.nlm.nih.gov/40986632/" ] }, { "id": "iusti_vulval_2021", "organization": "European vulval-guideline expert group / IUSTI-Europe", "title": "2021 European guideline for the management of vulval conditions", "edition_year": 2021, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://iusti.org/wp-content/uploads/2022/04/epub-vulval-conditions.pdf", "verification_depth": "full_text", "version_status": "2021 guideline; accepted and published 2022", "doi": "10.1111/jdv.18102", "supporting_urls": [], "notes": "The vulvodynia section explicitly names low-level laser. Statements about CO2 laser, ultraviolet excimer laser and laser surgery elsewhere are different interventions and are excluded.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Europe", "country_scope_kind": "region", "country_scope_basis": "Issuing organization or panel identified in the source: European vulval-guideline expert group / IUSTI-Europe. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://iusti.org/wp-content/uploads/2022/04/epub-vulval-conditions.pdf" ] }, { "id": "euroguiderm_acne_2025", "organization": "European Dermatology Forum / EuroGuiDerm acne guideline group", "title": "EuroGuiDerm Evidence-based Guideline for the Treatment of Acne – long version, Update 2025", "edition_year": 2025, "publication_year": 2026, "document_type": "clinical_practice_guideline", "url": "https://www.guidelines.edf.one/uploads/attachments/cmkmicwv8yrsarwjrzxnr41db-euroguiderm-acne-guideline-long-version.pdf", "verification_depth": "full_text", "version_status": "Update labelled 2025; companion short version published 2026; expires June 2030", "doi": "10.1111/jdv.70331", "supporting_urls": [ "https://pubmed.ncbi.nlm.nih.gov/41847993/", "https://onlinelibrary.wiley.com/doi/10.1111/jdv.70331" ], "notes": "Clinical rows follow the official long version. DOI/year 2026 refer to its published companion short version, not an extra guideline. Graphical recommendation tables on printed pp. 27, 32–33 were visually inspected. Open recommendation means no recommendation for or against. Blue-light monotherapy has a different low-strength recommendation, which is not transferred to red/NIR PBM. IPL, PDT and ablative laser are not treated as PBM.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Europe", "country_scope_kind": "region", "country_scope_basis": "Issuing organization or panel identified in the source: European Dermatology Forum / EuroGuiDerm acne guideline group. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.guidelines.edf.one/uploads/attachments/cmkmicwv8yrsarwjrzxnr41db-euroguiderm-acne-guideline-long-version.pdf" ] }, { "id": "japan_chronicpain_2021", "organization": "Japanese multidisciplinary chronic-pain guideline working group (10 collaborating professional societies)", "title": "慢性疼痛診療ガイドライン / Clinical Practice Guidelines for the Management of Chronic Pain", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://www.jhsnet.net/pdf/totsu_guideline_jp.pdf", "verification_depth": "full_text", "version_status": "2021 edition; official public main-guideline PDF", "doi": "", "supporting_urls": [ "https://www.hanmoto.com/bd/isbn/9784880039398" ], "notes": "Public society-hosted PDF contains the main recommendations through printed p. 276; the complete print book also has supplementary material. Japanese no-recommendation wording is retained, even where the narrative describes possible adjunctive benefit. The shoulder-stiffness chapter concerns katakori, not adhesive capsulitis or rotator cuff disease.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Japan", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Japanese multidisciplinary chronic-pain guideline working group (10 collaborating professional societies). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.jhsnet.net/pdf/totsu_guideline_jp.pdf" ] }, { "id": "alberta_lbp_2011", "organization": "Toward Optimized Practice (TOP), Alberta", "title": "Guideline for the Evidence-Informed Primary Care Management of Low Back Pain, 2nd edition", "edition_year": 2011, "publication_year": 2011, "document_type": "clinical_practice_guideline", "url": "https://www.cfpc.ca/CFPC/media/Resources/Pain-Management/Low_Back_Pain_Guidelines_Oct19.pdf", "verification_depth": "full_text", "version_status": "Historical 2011 second edition; superseded by third edition 2015/revision 2017", "doi": "", "supporting_urls": [], "notes": "Hosted filename Oct19 does not indicate a 2019 guideline. The document itself identifies Low Back Pain, 2011. CFPC is the host, not the issuing guideline panel. This historical edition is separate from the third edition and is not an independent evidence vote.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Canada", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Toward Optimized Practice (TOP), Alberta. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.cfpc.ca/CFPC/media/Resources/Pain-Management/Low_Back_Pain_Guidelines_Oct19.pdf" ] }, { "id": "alberta_lbp_2015", "organization": "Toward Optimized Practice (TOP), Alberta", "title": "Evidence-Informed Primary Care Management of Low Back Pain, 3rd edition (minor revision 2017)", "edition_year": 2015, "publication_year": 2015, "document_type": "clinical_practice_guideline", "url": "https://www.ihe.ca/public/uploaded/lbp-guideline%20(1).pdf", "verification_depth": "full_text", "version_status": "December 2015 third edition; minor revision 2017; later-version validity not established", "doi": "", "supporting_urls": [], "notes": "The source itself lists revised 2015 third edition and minor revision 2017. LLLT remains in the insufficient-evidence list; SR/RCT labels identify evidence sources, not a certainty grade. Do not relabel it a 2019 or 2026 recommendation.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Canada", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Toward Optimized Practice (TOP), Alberta. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.ihe.ca/public/uploaded/lbp-guideline%20(1).pdf" ] }, { "id": "dutch_achilles_2021", "organization": "Dutch Association of Sports Medicine-led multidisciplinary guideline panel", "title": "Dutch multidisciplinary guideline on Achilles tendinopathy", "edition_year": 2021, "publication_year": 2021, "document_type": "clinical_practice_guideline", "url": "https://bjsm.bmj.com/content/55/20/1125", "verification_depth": "full_text", "version_status": "2021 document", "doi": "10.1136/bjsports-2020-103867", "supporting_urls": [], "notes": "The additional-treatment list includes laser/light among passive modalities only after a core education, loading and exercise programme. Shared discussion must address uncertainty of additional benefit. No isolated PBM efficacy or certainty grade is inferred.", "checked_on": "2026-10-16", "added_in": "expansion_05", "country_scope": "Netherlands", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Dutch Association of Sports Medicine-led multidisciplinary guideline panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://bjsm.bmj.com/content/55/20/1125" ] }, { "id": "german_knee_2024", "organization": "German Society for Orthopaedics and Trauma Surgery (DGOU) and multidisciplinary panel", "title": "Prävention und Therapie der Gonarthrose: S3-Leitlinie, Version 5.0 (AWMF 187-050)", "edition_year": 2024, "publication_year": 2024, "document_type": "clinical_practice_guideline", "url": "https://register.awmf.org/assets/guidelines/187-050l_S3_Gonarthrose_2025-05.pdf", "verification_depth": "full_text", "version_status": "Version 5.0, dated 12 July 2024; register valid to July 2029; PDF path dated May 2025", "doi": "", "supporting_urls": [ "https://register.awmf.org/de/leitlinien/detail/187-050" ], "notes": "Recommendation 39 strongly advises against a group including laser, adopting NICE NG226 recommendation 1.3.9. The displayed very-low-certainty GRADE excerpts concern NMES/ultrasound, not a verified laser-specific certainty grade. Laser class is unspecified in the recommendation table.", "checked_on": "2026-10-16", "added_in": "expansion_06", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: German Society for Orthopaedics and Trauma Surgery (DGOU) and multidisciplinary panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://register.awmf.org/assets/guidelines/187-050l_S3_Gonarthrose_2025-05.pdf" ] }, { "id": "german_fibro_2017", "organization": "German Pain Society (Deutsche Schmerzgesellschaft) and multidisciplinary panel", "title": "Definition, Pathophysiologie, Diagnostik und Therapie des Fibromyalgiesyndroms: S3-Leitlinie, 2. Aktualisierung 2017 (AWMF 145-004)", "edition_year": 2017, "publication_year": 2017, "document_type": "clinical_practice_guideline", "url": "https://www.dgppn.de/_Resources/Persistent/24de2ddc18d5efabc1c0d9d35d8511a85d92e42a/S3_Fibromyalgiesyndrom_2017_lang.pdf", "verification_depth": "full_text", "version_status": "Historical 2017 edition; official register copy marked expired", "doi": "", "supporting_urls": [ "https://register.awmf.org/assets/guidelines/145-004l_S3_Fibromyalgiesyndrom_2019-11_1-abgelaufen.pdf", "https://epub.ub.uni-muenchen.de/50614/" ], "notes": "Laser therapy has a negative recommendation, EL3a and strong consensus. Strong consensus is not a strong positive recommendation. The historical expiry is explicit; this is not presented as a newly issued 2026 assessment.", "checked_on": "2026-10-16", "added_in": "expansion_06", "country_scope": "Germany", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: German Pain Society (Deutsche Schmerzgesellschaft) and multidisciplinary panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.dgppn.de/_Resources/Persistent/24de2ddc18d5efabc1c0d9d35d8511a85d92e42a/S3_Fibromyalgiesyndrom_2017_lang.pdf" ] }, { "id": "cdc_opioid_2022", "organization": "US Centers for Disease Control and Prevention (CDC)", "title": "CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm", "verification_depth": "full_text", "version_status": "2022 guideline", "doi": "10.15585/mmwr.rr7103a1", "supporting_urls": [], "notes": "Recommendation 2 implementation considerations name LLLT as a condition-specific noninvasive option for low-back pain. Category A / evidence type 2 grades the broader nonopioid recommendation, not LLLT alone. A named implementation option is recorded separately from an independently graded PBM recommendation.", "checked_on": "2026-10-16", "added_in": "expansion_06", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: US Centers for Disease Control and Prevention (CDC). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.cdc.gov/mmwr/volumes/71/rr/rr7103a1.htm" ] }, { "id": "ireland_lymph_2022", "organization": "Health Service Executive Ireland / Lymphoedema Network Northern Ireland / Public Health Agency NI", "title": "All-Ireland Lymphoedema Guidelines 2022 for the Diagnosis, Assessment and Management of Lymphoedema", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://www.lnni.org/sites/default/files/documents/Lymphoedema%20Guidelines%20Interactive%20Pages.pdf", "verification_depth": "full_text", "version_status": "V1/2022; publication September 2022; review due June 2027", "doi": "", "supporting_urls": [ "https://www2.healthservice.hse.ie/organisation/national-pppgs/all-ireland-lymphoedema-guidelines/" ], "notes": "GQ92.1 describes support for safe laser use but strongly prioritizes conventional treatments such as CDT because of time and cost. Own evidence grade C and strong recommendation must not be confused with a strong laser-efficacy endorsement or the separately cited SIO C-grade recommendation.", "checked_on": "2026-10-16", "added_in": "expansion_06", "country_scope": "Ireland & Northern Ireland", "country_scope_kind": "cross_border", "country_scope_basis": "The All-Ireland guideline is jointly issued by HSE Ireland and Northern Ireland bodies. Its scope spans Ireland and Northern Ireland, rather than a single country.", "country_scope_source_urls": [ "https://www.lnni.org/sites/default/files/documents/Lymphoedema%20Guidelines%20Interactive%20Pages.pdf" ] }, { "id": "dutch_lymph_2014", "organization": "Dutch Society for Dermatology and Venereology (NVDV) and multidisciplinary panel", "title": "Richtlijn lymfoedeem: Multidisciplinaire evidence-based richtlijn, versie 01-05-2014", "edition_year": 2014, "publication_year": 2014, "document_type": "clinical_practice_guideline", "url": "https://lymfoedeem.nl/wp-content/uploads/2022/10/Richtlijn-Lymfoedeem.pdf", "verification_depth": "full_text", "version_status": "Historical full 2014 edition; modular revision 2023/2024 exists", "doi": "", "supporting_urls": [ "https://richtlijnendatabase.nl/richtlijn/lymfoedeem_herziening_2023/conservatieve_behandeling_lymfoedeem.html" ], "notes": "The 2014 full guideline states that evidence for soft lasers reducing lymphoedema is lacking. The 2022 upload path does not change the edition year. A current PBM recommendation is not inferred from the 2023/2024 module, whose laser search hits were references rather than a verified new therapeutic statement.", "checked_on": "2026-10-16", "added_in": "expansion_06", "country_scope": "Netherlands", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: Dutch Society for Dermatology and Venereology (NVDV) and multidisciplinary panel. The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://lymfoedeem.nl/wp-content/uploads/2022/10/Richtlijn-Lymfoedeem.pdf" ] }, { "id": "china_olp_nhc_2022", "organization": "National Health Commission of the People's Republic of China (NHC)", "title": "口腔扁平苔藓诊疗指南（2022年版） / Guideline for diagnosis and treatment of oral lichen planus (2022 edition)", "edition_year": 2022, "publication_year": 2022, "document_type": "clinical_practice_guideline", "url": "https://www.nhc.gov.cn/yzygj/c100068/202210/0e87231c99f649f99fccea827aa232b7/files/1732871384894_47567.pdf", "verification_depth": "full_text", "version_status": "2022 national issued guideline; 15-page document", "doi": "", "supporting_urls": [ "http://www.hunan.gov.cn/zqt/zcsd/202210/t20221031_29111470.html" ], "notes": "Section III(4) explicitly permits weak/low-power laser therapy and separately lists photodynamic therapy. No laser-specific grade or dosing protocol is provided. This government guideline is distinct from the Chinese Stomatological Association revised OLP guideline published in the same year; its DOI is not transferred here.", "checked_on": "2026-10-16", "added_in": "expansion_06", "country_scope": "China", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: National Health Commission of the People's Republic of China (NHC). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://www.nhc.gov.cn/yzygj/c100068/202210/0e87231c99f649f99fccea827aa232b7/files/1732871384894_47567.pdf" ] }, { "id": "acp_aafp_acute_2020", "organization": "American College of Physicians (ACP) / American Academy of Family Physicians (AAFP)", "title": "Nonpharmacologic and Pharmacologic Management of Acute Pain From Non–Low Back, Musculoskeletal Injuries in Adults: A Clinical Guideline From the ACP and AAFP", "edition_year": 2020, "publication_year": 2020, "document_type": "clinical_practice_guideline", "url": "https://doi.org/10.7326/M19-3602", "verification_depth": "full_text", "version_status": "2020 guideline", "doi": "10.7326/M19-3602", "supporting_urls": [ "https://www.multiplechronicconditions.org/wp-content/uploads/2023/01/2020-ACP-AAFP-Guidelines-for-Acute-Pain-Musculoskeletal-Injuries.pdf", "https://www.aafp.org/afp/2020/1201/p697" ], "notes": "Complete published guideline PDF was read from a public nonprofit-hosted copy and corroborated against AAFP's official summary. Pain at 1–7 days and overall symptom relief differ. The outcome section calls symptom-relief evidence moderate certainty but the recommendation rationale calls it low certainty. Laser is not among the recommended interventions because the panel required improvement in at least two outcomes; no blanket recommendation against laser is inferred.", "checked_on": "2026-10-16", "added_in": "expansion_06", "country_scope": "United States", "country_scope_kind": "country", "country_scope_basis": "Issuing organization or panel identified in the source: American College of Physicians (ACP) / American Academy of Family Physicians (AAFP). The label describes the issuer or stated scope, not the nationality of individual authors or universal geographical applicability.", "country_scope_source_urls": [ "https://doi.org/10.7326/M19-3602" ] } ], "statements": [ { "id": "OM-MASCC-HSCT", "document_id": "mascc_mucositis", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention: HSCT", "condition_fi": "Suun mukosiitin ehkäisy kantasolusiirrossa", "direction": "recommended", "strength_as_reported": "Recommendation", "evidence_certainty_as_reported": "LoE I", "scope": "Adults receiving high-dose conditioning for HSCT, with or without total body irradiation", "summary_en": "Recommends intraoral PBM to prevent oral mucositis in the specified transplant setting.", "summary_fi": "Suunsisäistä PBM-hoitoa suositellaan mukosiitin ehkäisyyn aikuisille suuriannoksisen kantasolusiirron esihoidon yhteydessä.", "locator": "Photobiomodulation section; Table 1, PBM row 1", "evidence_anchor": "A recommendation for the prevention of OM with intraoral PBM therapy in patients who undergo HSCT", "caveat_en": "Use a complete guideline-specified protocol; this is a prevention recommendation.", "caveat_fi": "Käyttöaihe on ehkäisy. Suositus koskee määriteltyjä hoitoprotokollia.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-MASCC-RT", "document_id": "mascc_mucositis", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention: head and neck radiotherapy", "condition_fi": "Suun mukosiitin ehkäisy pään ja kaulan sädehoidossa", "direction": "recommended", "strength_as_reported": "Recommendation", "evidence_certainty_as_reported": "LoE II", "scope": "Adults receiving head and neck radiotherapy without chemotherapy", "summary_en": "Recommends intraoral PBM to prevent oral mucositis during head and neck radiotherapy without chemotherapy.", "summary_fi": "Suunsisäistä PBM-hoitoa suositellaan mukosiitin ehkäisyyn pään ja kaulan sädehoidossa ilman samanaikaista solunsalpaajahoitoa.", "locator": "Photobiomodulation section; Table 1, PBM row 2", "evidence_anchor": "A recommendation for the prevention of OM with intraoral PBM therapy in patients with cancer who receive H&N RT (without CT)", "caveat_en": "Do not extend the recommendation to every cancer regimen or delivery route.", "caveat_fi": "Suositus on potilasryhmä- ja protokollakohtainen.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-MASCC-CRT", "document_id": "mascc_mucositis", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention: head and neck chemoradiotherapy", "condition_fi": "Suun mukosiitin ehkäisy pään ja kaulan kemosädehoidossa", "direction": "recommended", "strength_as_reported": "Recommendation", "evidence_certainty_as_reported": "LoE I", "scope": "Adults receiving head and neck radiotherapy with chemotherapy", "summary_en": "Recommends intraoral PBM to prevent oral mucositis during head and neck chemoradiotherapy.", "summary_fi": "Suunsisäistä PBM-hoitoa suositellaan mukosiitin ehkäisyyn pään ja kaulan kemosädehoidossa.", "locator": "Photobiomodulation section; Table 1, PBM row 3", "evidence_anchor": "A recommendation for the prevention of OM with intraoral PBM therapy in patients with cancer who receive H&N RT with CT", "caveat_en": "2019 PBM paper and 2020 consolidated guideline are the same update, not two independent recommendations.", "caveat_fi": "Dian 2019 julkaisu ja vuoden 2020 koontisuositus kuuluvat samaan päivitykseen.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-POGO-HSCT", "document_id": "pogo_mucositis", "specialty": "Pediatric oncology", "condition_en": "Oral mucositis prevention: pediatric HSCT", "condition_fi": "Lasten suun mukosiitin ehkäisy kantasolusiirrossa", "direction": "recommended", "strength_as_reported": "Strong recommendation", "evidence_certainty_as_reported": "High-quality evidence", "scope": "Children undergoing autologous or allogeneic HSCT", "summary_en": "Recommends intraoral PBM in the 620–750 nm spectrum for pediatric autologous or allogeneic HSCT.", "summary_fi": "Suunsisäistä PBM-hoitoa (620–750 nm) suositellaan lapsille autologisen tai allogeenisen kantasolusiirron yhteydessä.", "locator": "Official COG endorsed-guideline compilation, PDF p. 43, recommendation 4", "evidence_anchor": "Use intraoral photobiomodulation therapy in the red light spectrum", "caveat_en": "Strength and quality verified in the official COG reproduction of POGO 2021. Recommendation 4 covers HSCT and head/neck carcinoma; other pediatric head/neck cancers have a separate conditional recommendation.", "caveat_fi": "Vahvuus ja näytön laatu tarkistettu POGO 2021 -suosituksen virallisesta COG-toisinnosta. Suositus 4 koskee kantasolusiirtoja ja pään ja kaulan karsinoomia; muilla lasten pään ja kaulan syövillä on erillinen ehdollinen suositus.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-16", "verification_depth": "official_recommendation_summary", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-POGO-RT", "document_id": "pogo_mucositis", "specialty": "Pediatric oncology", "condition_en": "Oral mucositis prevention: pediatric head and neck radiotherapy", "condition_fi": "Lasten suun mukosiitin ehkäisy pään ja kaulan sädehoidossa", "direction": "recommended", "strength_as_reported": "Strong recommendation", "evidence_certainty_as_reported": "High-quality evidence", "scope": "Pediatric head and neck carcinoma receiving radiotherapy", "summary_en": "Recommends intraoral PBM in the 620–750 nm spectrum for pediatric head and neck carcinoma patients receiving radiotherapy.", "summary_fi": "Suunsisäistä PBM-hoitoa suositellaan sädehoitoa saaville lapsille, joilla on pään tai kaulan alueen karsinooma.", "locator": "Official COG endorsed-guideline compilation, PDF p. 43, recommendation 4", "evidence_anchor": "Use intraoral photobiomodulation therapy in the red light spectrum", "caveat_en": "Strength and quality verified in the official COG reproduction of POGO 2021. Recommendation 4 covers HSCT and head/neck carcinoma; other pediatric head/neck cancers have a separate conditional recommendation.", "caveat_fi": "Vahvuus ja näytön laatu tarkistettu POGO 2021 -suosituksen virallisesta COG-toisinnosta. Suositus 4 koskee kantasolusiirtoja ja pään ja kaulan karsinoomia; muilla lasten pään ja kaulan syövillä on erillinen ehdollinen suositus.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-16", "verification_depth": "official_recommendation_summary", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-NICE", "document_id": "nice_mucositis", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention or treatment", "condition_fi": "Syöpähoitoihin liittyvän suun mukosiitin ehkäisy tai hoito", "direction": "recommended", "strength_as_reported": "Procedure may be used under standard arrangements", "evidence_certainty_as_reported": "", "scope": "Radiotherapy- or chemotherapy-related oral mucositis", "summary_en": "Allows the procedure with standard arrangements for clinical governance, consent and audit; efficacy evidence is adequate in quality and quantity.", "summary_fi": "Menetelmää voidaan käyttää tavanomaisin laadunvarmistus-, suostumus- ja seurantajärjestelyin. NICE pitää vaikuttavuusnäyttöä määrältään ja laadultaan riittävänä.", "locator": "Recommendation 1.1", "evidence_anchor": "Evidence on efficacy is adequate in quality and quantity", "caveat_en": "Interventional/procedure guidance; it is not phrased as a universal first-line treatment requirement.", "caveat_fi": "Toimenpidesuositus; ei yleinen vaatimus käyttää ensilinjan hoitona.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "procedure_guidance" }, { "id": "OM-ESMO-HSCT", "document_id": "esmo_mucositis", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention: HSCT", "condition_fi": "Suun mukosiitin ehkäisy kantasolusiirrossa", "direction": "recommended", "strength_as_reported": "Recommends", "evidence_certainty_as_reported": "LoE II", "scope": "High-dose chemotherapy conditioning for HSCT, with or without total body irradiation", "summary_en": "Recommends LLLT to prevent oral mucositis in HSCT conditioning using the specified regimen.", "summary_fi": "Laserhoitoa suositellaan mukosiitin ehkäisyyn kantasolusiirron suuriannoksisen esihoidon yhteydessä, määritellyllä hoitoprotokollalla.", "locator": "Table 2, recommendation 3", "evidence_anchor": "be used to *prevent* oral mucositis in patients receiving HSCT", "caveat_en": "The 2015 ESMO document adopts earlier MASCC/ISOO guidance; do not present it as a new independent evidence base.", "caveat_fi": "ESMO 2015 hyödyntää aiempaa MASCC/ISOO-suositusta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-ESMO-RT", "document_id": "esmo_mucositis", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention: radiotherapy without chemotherapy", "condition_fi": "Suun mukosiitin ehkäisy sädehoidossa ilman solunsalpaajaa", "direction": "may_consider", "strength_as_reported": "Suggests", "evidence_certainty_as_reported": "LoE III", "scope": "Head and neck radiotherapy without concomitant chemotherapy", "summary_en": "Suggests LLLT to prevent oral mucositis in head and neck radiotherapy without chemotherapy.", "summary_fi": "Laserhoitoa ehdotetaan mukosiitin ehkäisyyn pään ja kaulan sädehoidossa ilman samanaikaista solunsalpaajahoitoa.", "locator": "Table 3, suggestion 3", "evidence_anchor": "low-level laser therapy (wavelength ∼632.8 nm)", "caveat_en": "Older ESMO statement; newer MASCC/ISOO guidance is stronger for this setting.", "caveat_fi": "Vanhempi ESMO-suositus; MASCC/ISOO 2019/2020 on tässä käyttöaiheessa vahvempi.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RD-MASCC-PREVENT", "document_id": "mascc_dermatitis", "specialty": "Oncology / dermatology", "condition_en": "Acute radiation dermatitis prevention: breast cancer", "condition_fi": "Akuutin sädeihottuman ehkäisy rintasyövässä", "direction": "recommended", "strength_as_reported": "Consensus to recommend; 27/34 (79%)", "evidence_certainty_as_reported": "", "scope": "People with breast cancer receiving radiotherapy; prevention of acute radiation dermatitis", "summary_en": "Recommends PBM / low-level laser for prevention of acute radiation dermatitis in breast cancer.", "summary_fi": "PBM-hoitoa suositellaan rintasyövän sädehoitoon liittyvän akuutin sädeihottuman ehkäisyyn.", "locator": "PDF p. 4, prevention recommendations, Laser therapy", "evidence_anchor": "photobiomodulation or", "caveat_en": "Scope is breast cancer prevention; not all cancer sites or treatment of established dermatitis.", "caveat_fi": "Suositus koskee rintasyövän sädehoidon haitan ehkäisyä, ei kaikkia syöpätyyppejä.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RD-MASCC-TREAT", "document_id": "mascc_dermatitis", "specialty": "Oncology / dermatology", "condition_en": "Established acute radiation dermatitis treatment", "condition_fi": "Jo kehittyneen akuutin sädeihottuman hoito", "direction": "against", "strength_as_reported": "Not recommended; 28/33 (85%) would not recommend", "evidence_certainty_as_reported": "", "scope": "Treatment of established acute radiation dermatitis", "summary_en": "The management consensus table lists PBM / low-level laser for established acute radiation dermatitis as not recommended.", "summary_fi": "Konsensustaulukossa PBM-hoitoa ei suositella jo kehittyneen akuutin sädeihottuman hoitoon.", "locator": "Table 2, PDF p. 9, Laser therapy", "evidence_anchor": "Photobiomodulation therapy or low-level laser therapy", "caveat_en": "A Delphi recommendation about clinical use, not proof of no biological effect. Distinct from the positive breast-cancer prevention recommendation.", "caveat_fi": "Konsensus koskee kliinistä käyttöä, ei osoita vaikutuksettomuutta. Eri kanta kuin rintasyövän sädeihottuman ehkäisyssä.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "XERO-ASCO", "document_id": "asco_xerostomia", "specialty": "Oncology / oral care", "condition_en": "Radiotherapy-associated salivary gland hypofunction / xerostomia", "condition_fi": "Sädehoitoon liittyvä sylkirauhasten vajaatoiminta ja suun kuivuus", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation for or against", "evidence_certainty_as_reported": "Insufficient evidence", "scope": "During radiotherapy for head and neck cancer", "summary_en": "Evidence is insufficient to recommend for or against low-level laser during head and neck radiotherapy to prevent hypofunction / xerostomia.", "summary_fi": "Näyttö ei riitä suositukseen matalatehoisen laserin puolesta tai sitä vastaan pään ja kaulan sädehoidon aikana.", "locator": "Recommendation 1.7; official summary PDF pp. 2–3", "evidence_anchor": "Evidence remains insufficient for a recommendation for or against", "caveat_en": "Do not transfer the positive mucositis prevention recommendation to xerostomia.", "caveat_fi": "Mukosiitin ehkäisysuositusta ei siirretä suun kuivuuden hoitoon.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "official_recommendation_summary", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ORN-ASCO", "document_id": "asco_orn", "specialty": "Oncology / oral surgery", "condition_en": "Osteoradionecrosis prevention", "condition_fi": "Leukaluun osteoradionekroosin ehkäisy", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation possible", "evidence_certainty_as_reported": "", "scope": "Patients with head and neck cancer receiving radiotherapy", "summary_en": "No recommendation was possible for PBM to prevent osteoradionecrosis.", "summary_fi": "PBM-hoidosta ei voitu antaa suositusta osteoradionekroosin ehkäisyyn.", "locator": "Abstract, Recommendations", "evidence_anchor": "No recommendation was possible", "caveat_en": "This statement concerns prevention; it does not establish efficacy for treatment of existing necrosis.", "caveat_fi": "Kannanotto koskee ehkäisyä.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "abstract", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "CTS-APTA-2026", "document_id": "apta_cts_2026", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Carpal tunnel syndrome", "condition_fi": "Rannekanavaoireyhtymä", "direction": "may_consider", "strength_as_reported": "C", "evidence_certainty_as_reported": "", "scope": "Nonsurgically managed mild to moderate CTS; short-term pain and function", "summary_en": "Clinicians may use LLLT or HILT for short-term improvement in pain and function.", "summary_fi": "LLLT- tai HILT-laserhoitoa voidaan käyttää lievän tai keskivaikean, ilman leikkausta hoidettavan rannekanavaoireyhtymän kivun ja toiminnan lyhytaikaiseen parantamiseen.", "locator": "PDF pp. 3 and 33; 2026 Recommendation", "evidence_anchor": "Clinicians may use either LLLT or HILT", "caveat_en": "Combines LLLT and HILT. Short-term recommendation; not a long-term efficacy claim.", "caveat_fi": "Suositus kattaa sekä matala- että suuritehoisen laserin ja koskee lyhytaikaista vaikutusta.", "intervention": "LLLT and HILT in a combined recommendation", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "CTS-AAOS-2024", "document_id": "aaos_cts_2024", "specialty": "Orthopedics", "condition_en": "Carpal tunnel syndrome: long-term outcomes", "condition_fi": "Rannekanavaoireyhtymän pitkäaikaistulokset", "direction": "no_benefit", "strength_as_reported": "Limited option (downgraded)", "evidence_certainty_as_reported": "High (for grouped nonoperative evidence; not a laser-only certainty grade)", "scope": "Long-term patient-reported outcomes; nonsurgical treatments", "summary_en": "Lists laser among nonsurgical interventions that do not improve long-term patient-reported outcomes.", "summary_fi": "Laser kuuluu hoitoihin, joiden ei todeta parantavan potilaan raportoimia pitkäaikaistuloksia.", "locator": "PDF pp. 10 and 35, Non-operative treatments: long-term", "evidence_anchor": "do not improve long-term patient reported outcomes", "caveat_en": "The High rating belongs to the grouped recommendation, not a separately verified laser-only evidence grade; short- and long-term claims differ.", "caveat_fi": "High-luokitus koskee yhdistettyä suosituskokonaisuutta, ei erikseen arvioitua laser-näyttöä. Kanta koskee pitkäaikaistuloksia.", "intervention": "Laser therapy; multiple nonoperative treatments grouped", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "CTS-AAOS-2016", "document_id": "aaos_cts_2016", "specialty": "Orthopedics", "condition_en": "Carpal tunnel syndrome: historical AAOS statement", "condition_fi": "Rannekanavaoireyhtymä: AAOS:n vanha suositus", "direction": "may_consider", "strength_as_reported": "Limited", "evidence_certainty_as_reported": "", "scope": "Laser compared with placebo", "summary_en": "Limited evidence suggested laser might be effective compared with placebo.", "summary_fi": "Rajallinen näyttö viittasi laserhoidon mahdolliseen tehoon lumehoitoon verrattuna.", "locator": "PDF p. 11, Laser therapy", "evidence_anchor": "laser therapy might be effective compared to placebo", "caveat_en": "Historical; replaced by AAOS 2024. Do not label this the current AAOS position.", "caveat_fi": "Historiallinen: AAOS 2024 korvaa tämän suosituksen.", "intervention": "PBM / low-level laser therapy", "historical": true, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "CTS-APTA-2019", "document_id": "apta_cts_2019", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Carpal tunnel syndrome: historical APTA statement", "condition_fi": "Rannekanavaoireyhtymä: APTA:n vanha suositus", "direction": "against", "strength_as_reported": "B", "evidence_certainty_as_reported": "", "scope": "Individuals with CTS; LLLT or nonlaser light therapy", "summary_en": "The 2019 guideline advised against LLLT and other nonlaser light therapy.", "summary_fi": "Vuoden 2019 suosituksessa kehotettiin olemaan käyttämättä LLLT:tä tai muuta ei-laser-valohoitoa.", "locator": "Reproduced in APTA 2026, PDF p. 32, 2019 Recommendation", "evidence_anchor": "Clinicians should not use LLLT", "caveat_en": "Historical; reversed for short-term use in the 2026 revision.", "caveat_fi": "Historiallinen: vuoden 2026 päivitys sallii rajatun lyhytaikaisen käytön.", "intervention": "LLLT and other nonlaser light therapy", "historical": true, "checked_on": "2026-10-15", "verification_depth": "historical_recommendation_reproduced_in_2026_full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "RC-APTA", "document_id": "apta_rotator", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Calcific rotator cuff tendinopathy", "condition_fi": "Kalkkinen kiertäjäkalvosimen tendinopatia", "direction": "may_consider", "strength_as_reported": "C", "evidence_certainty_as_reported": "", "scope": "Adults with calcific rotator cuff tendinopathy; pain and disability", "summary_en": "Laser may be used alone or with active rehabilitation to reduce pain and disability in calcific tendinopathy.", "summary_fi": "Laserhoitoa voidaan käyttää yksin tai aktiivisen kuntoutuksen osana kalkkisen kiertäjäkalvosimen tendinopatian kipuun ja haittaan.", "locator": "Recommendation 31; PDF pp. 3 and 32", "evidence_anchor": "Clinicians may use laser therapy alone", "caveat_en": "The positive recommendation is specifically calcific; it must not be generalized to all rotator cuff pain.", "caveat_fi": "Myönteinen suositus on rajattu kalkkiseen tendinopatiaan.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "DRF-APTA", "document_id": "apta_radius", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Distal radius fracture rehabilitation", "condition_fi": "Värttinäluun alaosan murtuman kuntoutus", "direction": "recommended", "strength_as_reported": "B (grouped physical-agent recommendation)", "evidence_certainty_as_reported": "", "scope": "After operative or nonoperative distal radius fracture management; short-term rehabilitation", "summary_en": "Includes laser among physical agents to use as part of multimodal rehabilitation for short-term outcomes.", "summary_fi": "Laser sisältyy fysikaalisiin hoitoihin, joita suositellaan osana monimuotoista kuntoutusta murtuman leikkaus- tai konservatiivisen hoidon jälkeen.", "locator": "PDF pp. 3 and 50; Therapeutic modalities", "evidence_anchor": "including laser therapy", "caveat_en": "The B grade applies to a group of physical agents; not every listed outcome is separately established for laser alone.", "caveat_fi": "B-luokitus koskee useita fysikaalisia hoitoja kattavaa suositusta. Kaikkia lueteltuja tuloksia ei ole osoitettu erikseen laserille.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "HEEL-APTA", "document_id": "apta_heel", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Acute or chronic plantar fasciitis", "condition_fi": "Akuutti tai krooninen plantaarifaskiitti", "direction": "recommended", "strength_as_reported": "B", "evidence_certainty_as_reported": "", "scope": "Acute or chronic plantar fasciitis; short-term pain, within rehabilitation", "summary_en": "The 2023 recommendation says clinicians should use LLLT within rehabilitation to reduce short-term pain.", "summary_fi": "Vuoden 2023 suosituksessa LLLT:tä suositellaan kuntoutuksen osana lyhytaikaisen kivun vähentämiseen.", "locator": "Final published PDF p. 2; Interventions – Physical agents – Low-level laser therapy", "evidence_anchor": "Clinicians should use low-level laser therapy as part of a rehabilitation program", "caveat_en": "Final published B grade verified. The recommendation concerns short-term pain and use within a rehabilitation program.", "caveat_fi": "Lopullisen julkaisun B-luokka on tarkistettu. Suositus koskee lyhytaikaista kipua ja käyttöä kuntoutusohjelman osana.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ELBOW-APTA", "document_id": "apta_elbow", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Lateral elbow tendinopathy", "condition_fi": "Lateraalinen kyynärpään tendinopatia", "direction": "may_consider", "strength_as_reported": "C", "evidence_certainty_as_reported": "", "scope": "Lateral elbow tendinopathy; pain and grip strength; follow-up >4 weeks to 6 months", "summary_en": "Clinicians may use laser for pain and grip-strength improvement seen at follow-up beyond 4 weeks to 6 months.", "summary_fi": "Laserhoitoa voidaan käyttää kivun ja puristusvoiman parantamiseen; vaikutuksia on havaittu yli 4 viikon–6 kuukauden seurannassa.", "locator": "PDF pp. 3 and 41; Interventions: Laser", "evidence_anchor": "Clinicians may use laser therapy for improvements", "caveat_en": "Follow-up interval is not a prescribed treatment-course length. Evidence includes low- and high-intensity laser.", "caveat_fi": "Seurantaväli ei tarkoita hoitojakson pituutta. Aineistossa on sekä matala- että suuritehoista laseria.", "intervention": "LLLT / low-intensity laser and HILT evidence", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "KNEE-AAOS", "document_id": "aaos_knee", "specialty": "Orthopedics", "condition_en": "Knee osteoarthritis", "condition_fi": "Polven nivelrikko", "direction": "may_consider", "strength_as_reported": "Limited (downgraded)", "evidence_certainty_as_reported": "", "scope": "Knee osteoarthritis; pain and function; FDA-approved laser treatment as worded by source", "summary_en": "FDA-approved laser treatment may be used to improve pain and function.", "summary_fi": "Suosituksen sanamuodon mukaan FDA-hyväksyttyä laserhoitoa voidaan käyttää kivun ja toimintakyvyn parantamiseen; suositus on rajallinen.", "locator": "PDF pp. 9 and 43; Laser treatment", "evidence_anchor": "FDA-approved laser treatment may be used", "caveat_en": "This does not endorse all LED devices or all red-light treatments. APTA's resource listing is the same AAOS guideline.", "caveat_fi": "Ei ole yleinen kaikkia valohoitolaitteita koskeva suositus. APTA:n luettelossa oleva nivelrikkosuositus on sama AAOS-asiakirja.", "intervention": "Laser treatment (source terminology)", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ANKLE-APTA", "document_id": "apta_ankle", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Acute lateral ankle sprain", "condition_fi": "Akuutti nilkan ulkosivun nivelsidevamma", "direction": "may_consider", "strength_as_reported": "C", "evidence_certainty_as_reported": "", "scope": "Initial phase of acute lateral ankle sprain; pain", "summary_en": "Clinicians may use LLLT for pain reduction in the initial phase of an acute lateral ankle sprain.", "summary_fi": "LLLT:tä voidaan käyttää kivun lievittämiseen akuutin nilkan ulkosivun nivelsidevamman alkuvaiheessa.", "locator": "PDF pp. 3 and 33; Low-level laser therapy", "evidence_anchor": "Clinicians may use low-level laser therapy to reduce pain", "caveat_en": "A pain recommendation in the acute initial phase; not a claim about chronic ankle instability.", "caveat_fi": "Koskee alkuvaiheen kipua, ei kroonisen nilkkaepävakauden hoitoa.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACHILLES-APTA", "document_id": "apta_achilles", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Midportion Achilles tendinopathy", "condition_fi": "Akillesjänteen keskiosan tendinopatia", "direction": "against", "strength_as_reported": "C", "evidence_certainty_as_reported": "", "scope": "Midportion Achilles tendinopathy", "summary_en": "Clinicians should not use LLLT for midportion Achilles tendinopathy.", "summary_fi": "LLLT-hoitoa ei suositella akillesjänteen keskiosan tendinopatiaan.", "locator": "Summary and 2024 Recommendation: Physical agents – LLLT", "evidence_anchor": "Clinicians should not use low-level laser therapy", "caveat_en": "Applies to midportion tendinopathy; not automatically every insertional or acute Achilles disorder.", "caveat_fi": "Kohteena on jänteen keskiosan tendinopatia.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-APTA-CHRONIC", "document_id": "apta_neck", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Chronic neck pain with mobility deficits", "condition_fi": "Krooninen niskakipu, johon liittyy liikerajoitus", "direction": "recommended", "strength_as_reported": "B (multimodal recommendation)", "evidence_certainty_as_reported": "", "scope": "Chronic neck pain with mobility deficits; multimodal care", "summary_en": "Lists laser as one possible component of multimodal care with manual therapy and mixed exercise.", "summary_fi": "Laser mainitaan yhtenä monimuotoisen hoidon vaihtoehtoisena osana manuaalisen hoidon ja harjoittelun yhteydessä.", "locator": "Summary of recommendations, PDF p. 2", "evidence_anchor": "Dry needling, laser, or intermittent mechanical/manual traction", "caveat_en": "B applies to the multimodal recommendation; not standalone PBM treatment.", "caveat_fi": "B koskee yhdistelmähoitosuositusta, ei itsenäistä PBM-hoitoa.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-APTA-ACUTE", "document_id": "apta_neck", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Acute neck pain with radiating pain", "condition_fi": "Akuutti niskakipu, johon liittyy säteilykipu", "direction": "may_consider", "strength_as_reported": "C", "evidence_certainty_as_reported": "", "scope": "Acute neck pain with radiating pain", "summary_en": "Lists laser among options clinicians may provide for acute neck pain with radiating pain.", "summary_fi": "Laser mainitaan mahdollisena hoitovaihtoehtona akuutissa niskakivussa, johon liittyy säteilykipu.", "locator": "Summary of recommendations, PDF p. 3", "evidence_anchor": "laser, and short-term use of a cervical collar", "caveat_en": "Compare the different population definition and recommendation with OPTIMa 2016 grade III neck disorders.", "caveat_fi": "OPTIMa 2016 arvioi neurologisin löydöksin määriteltyä grade III -ryhmää eri tavalla.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LYMPH-APTA", "document_id": "apta_lymphedema", "specialty": "Oncologic rehabilitation", "condition_en": "Established breast cancer-related upper-extremity lymphedema", "condition_fi": "Rintasyöpään liittyvä yläraajan lymfaturvotus", "direction": "may_consider", "strength_as_reported": "B", "evidence_certainty_as_reported": "", "scope": "Established upper-extremity lymphedema; adjunct to compression or complete decongestive therapy (CDT)", "summary_en": "LLLT may be considered in combination with compression or CDT.", "summary_fi": "LLLT:tä voidaan harkita kompression tai kokonaisvaltaisen lymfaterapian lisänä jo todetussa yläraajan lymfaturvotuksessa.", "locator": "Table 1 and Low-level laser therapy section", "evidence_anchor": "Low-level laser therapy may be considered", "caveat_en": "The text does not recommend LLLT as standalone therapy.", "caveat_fi": "Tekstissä LLLT:tä ei suositella yksinään käytettäväksi.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LYMPH-ISL-2023", "document_id": "isl_2023", "specialty": "Lymphology", "condition_en": "Peripheral lymphedema", "condition_fi": "Perifeerinen lymfaturvotus", "direction": "descriptive_support", "strength_as_reported": "Narrative consensus; no formal recommendation grade", "evidence_certainty_as_reported": "Limited scientific evidence", "scope": "Lymphedema; pain and tissue mobility more than pure volume reduction", "summary_en": "Describes limited evidence supporting low-level laser, with more robust changes in pain and tissue mobility than in limb volume.", "summary_fi": "Konsensus kuvaa rajallista myönteistä näyttöä. Selvempiä muutoksia on kivussa ja kudoksen liikkuvuudessa kuin pelkässä turvotustilavuudessa.", "locator": "PDF p. 12; nonoperative treatment, Low level laser", "evidence_anchor": "There is some limit", "caveat_en": "Descriptive consensus text; not a strong graded endorsement.", "caveat_fi": "Kuvaileva konsensusmaininta, ei vahva luokiteltu suositus.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "society_consensus" }, { "id": "LYMPH-ISL-2020", "document_id": "isl_2020", "specialty": "Lymphology", "condition_en": "Peripheral lymphedema: historical consensus", "condition_fi": "Perifeerinen lymfaturvotus: vuoden 2020 konsensus", "direction": "descriptive_support", "strength_as_reported": "Narrative consensus; no formal recommendation grade", "evidence_certainty_as_reported": "", "scope": "Lymphedema; small studies and limited meta-analysis", "summary_en": "Describes benefits reported in small studies, especially pain and tissue mobility rather than pure volume reduction.", "summary_fi": "Kuvaa pienissä tutkimuksissa havaittuja hyötyjä etenkin kipuun ja kudoksen liikkuvuuteen.", "locator": "PDF p. 11, Low level laser", "evidence_anchor": "Reports with small numbers", "caveat_en": "Historical version; the 2023 ISL consensus is available.", "caveat_fi": "Vanhempi versio; vuoden 2023 ISL-konsensus on saatavilla.", "intervention": "PBM / low-level laser therapy", "historical": true, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "LBP-ACP", "document_id": "acp_back", "specialty": "Musculoskeletal / primary care", "condition_en": "Chronic low back pain", "condition_fi": "Krooninen alaselkäkipu", "direction": "recommended", "strength_as_reported": "Strong recommendation for initial nonpharmacological options", "evidence_certainty_as_reported": "Low-quality evidence for LLLT", "scope": "Chronic low back pain; initial nonpharmacological management", "summary_en": "Includes LLLT among initial nonpharmacological treatment choices.", "summary_fi": "LLLT sisältyy kroonisen alaselkäkivun ensivaiheen lääkkeettömiin hoitovaihtoehtoihin.", "locator": "Abstract, Recommendation 2", "evidence_anchor": "low-level laser therapy", "caveat_en": "The recommendation for a menu of nonpharmacological options is strong; the evidence for LLLT is low quality. It does not require all patients to receive laser.", "caveat_fi": "Vahva suositus koskee lääkkeettömien vaihtoehtojen kokonaisuutta. LLLT:n näyttö on heikkolaatuista.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "abstract", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-NASS-PAIN", "document_id": "nass_back", "specialty": "Spine care", "condition_en": "Low back pain: laser plus exercise, pain", "condition_fi": "Alaselkäkipu: laser ja harjoittelu, kipu", "direction": "may_consider", "strength_as_reported": "B", "evidence_certainty_as_reported": "", "scope": "Laser (low- or high-level) plus exercise versus either alone; short-term pain", "summary_en": "Suggests laser plus exercise provides better short-term pain relief than either alone.", "summary_fi": "Laserin ja harjoittelun yhdistelmän arvioidaan lievittävän kipua lyhytaikaisesti paremmin kuin kumpikaan yksinään.", "locator": "Summary and Physical medicine section; laser therapy recommendations", "evidence_anchor": "the combination of laser therapy (low-level or high level)", "caveat_en": "The recommendation combines low- and high-level lasers and concerns pain, not automatically function.", "caveat_fi": "Suositus yhdistää matala- ja suuritehoisen laserin; kipu ja toimintakyky arvioidaan erikseen.", "intervention": "Low-level or high-level laser with exercise", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-NASS-FUNCTION", "document_id": "nass_back", "specialty": "Spine care", "condition_en": "Low back pain: laser plus exercise, function", "condition_fi": "Alaselkäkipu: laser ja harjoittelu, toimintakyky", "direction": "insufficient_evidence", "strength_as_reported": "I (conflicting evidence)", "evidence_certainty_as_reported": "", "scope": "Laser plus exercise versus either alone; short-term function", "summary_en": "Evidence conflicts on whether the combination improves short-term function.", "summary_fi": "Yhdistelmän vaikutuksesta lyhytaikaiseen toimintakykyyn on ristiriitaista näyttöä.", "locator": "Summary and Physical medicine section", "evidence_anchor": "There is conflicting evidence that the combination of laser therapy", "caveat_en": "NASS grade I means insufficient/conflicting evidence, not top-tier evidence level I.", "caveat_fi": "NASS:n I tarkoittaa riittämätöntä tai ristiriitaista näyttöä; se ei ole korkein näyttötaso.", "intervention": "Low-level or high-level laser with exercise", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-NASS-ALONE", "document_id": "nass_back", "specialty": "Spine care", "condition_en": "Low back pain: laser alone versus exercise", "condition_fi": "Alaselkäkipu: laser yksin verrattuna harjoitteluun", "direction": "no_benefit", "strength_as_reported": "B", "evidence_certainty_as_reported": "", "scope": "Low- or high-level laser alone versus exercise; short-term", "summary_en": "Suggests no short-term benefit of laser compared with exercise alone.", "summary_fi": "Laserin yksinään ei arvioida tuovan lyhytaikaista hyötyä harjoitteluun verrattuna.", "locator": "Summary and Physical medicine section", "evidence_anchor": "there is no short-term benefit of laser therapy", "caveat_en": "Different comparison from laser plus exercise; preserve both statements.", "caveat_fi": "Vertailu on eri kuin yhdistelmähoitorivillä.", "intervention": "Low-level or high-level laser", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-NASS-ACUP", "document_id": "nass_back", "specialty": "Spine care", "condition_en": "Chronic low back pain: laser acupuncture", "condition_fi": "Krooninen alaselkäkipu: laserakupunktio", "direction": "no_benefit", "strength_as_reported": "A", "evidence_certainty_as_reported": "", "scope": "Laser acupuncture versus sham; short- and medium-term outcomes", "summary_en": "Laser acupuncture provides no short- or medium-term benefit over sham.", "summary_fi": "Laserakupunktion ei todeta tuovan lyhyen tai keskipitkän aikavälin hyötyä lumehoitoon verrattuna.", "locator": "Summary and Physical medicine section", "evidence_anchor": "Laser acupuncture provides no short-term or medium-term benefit", "caveat_en": "Laser acupuncture is a distinct delivery approach from tissue-directed laser therapy.", "caveat_fi": "Laserakupunktio erotetaan suoraan oirekudokseen kohdistetusta laserhoidosta.", "intervention": "Laser acupuncture", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-VA", "document_id": "va_back", "specialty": "Musculoskeletal / primary care", "condition_en": "Low back pain", "condition_fi": "Alaselkäkipu", "direction": "insufficient_evidence", "strength_as_reported": "Neither for nor against", "evidence_certainty_as_reported": "Insufficient evidence", "scope": "Low back pain; laser grouped with cupping, TENS and ultrasound", "summary_en": "Evidence is insufficient to recommend for or against laser therapy.", "summary_fi": "Näyttö ei riitä suositukseen laserhoidon puolesta tai sitä vastaan.", "locator": "Recommendation 17; PDF pp. 24 and 47", "evidence_anchor": "insufficient evidence to recommend for or against cupping", "caveat_en": "Do not classify this as a recommendation to use laser.", "caveat_fi": "Kyse on suosituksen puuttumisesta.", "intervention": "Laser therapy (source terminology)", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-OPTIMA-CHRONIC", "document_id": "optima_neck", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Persistent neck pain, NAD grades I–II", "condition_fi": "Pitkittynyt niskakipu, NAD-luokat I–II", "direction": "may_consider", "strength_as_reported": "Clinicians may consider", "evidence_certainty_as_reported": "", "scope": "NAD grades I–II for >3 months, combined with structured patient education", "summary_en": "May consider LLLT together with structured patient education.", "summary_fi": "Matalatehoista laseria voidaan harkita potilasohjauksen rinnalla, kun NAD-luokan I–II niskakipu on kestänyt yli kolme kuukautta.", "locator": "Recommendation 5", "evidence_anchor": "For NAD grades I-II >3 months duration", "caveat_en": "Preserve the duration and absence of grade III neurological signs.", "caveat_fi": "Rajaus on yli kolme kuukautta kestänyt NAD I–II -oireisto.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text_author_article_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-OPTIMA-GRADEIII", "document_id": "optima_neck", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Recent-onset neck disorder with neurological signs, NAD grade III", "condition_fi": "Tuore niskavaiva ja neurologiset löydökset, NAD III", "direction": "against", "strength_as_reported": "Clinicians should not offer", "evidence_certainty_as_reported": "", "scope": "NAD grade III, duration ≤3 months", "summary_en": "Advises against LLLT for recent-onset grade III neck disorders.", "summary_fi": "LLLT:tä ei suositella enintään kolme kuukautta kestäneeseen NAD III -niskavaivaan.", "locator": "Recommendation 6", "evidence_anchor": "For NAD grade III ≤3 months duration", "caveat_en": "This differs from APTA 2017's acute radiating-pain statement; the clinical category and framework must remain visible.", "caveat_fi": "Tämä eroaa APTA 2017:n säteilykipusuosituksesta; luokitus ja potilasryhmä säilytetään näkyvissä.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text_author_article_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "SHOULDER-OPTIMA", "document_id": "optima_shoulder", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Soft tissue shoulder pain", "condition_fi": "Olkapään pehmytkudoskipu", "direction": "may_consider", "strength_as_reported": "Clinicians may consider", "evidence_certainty_as_reported": "", "scope": "Shoulder pain of any duration within the guideline's soft-tissue scope", "summary_en": "May consider low-level laser for shoulder pain of any duration.", "summary_fi": "Matalatehoista laseria voidaan harkita olkapään pehmytkudoskipuun oireen kestosta riippumatta.", "locator": "Abstract recommendation c; recommendations for recent and persistent shoulder pain", "evidence_anchor": "for shoulder pain of any duration, consider low-level laser therapy", "caveat_en": "Broader shoulder-pain scope than the 2025 rotator cuff calcific recommendation.", "caveat_fi": "Kohderajaus on laajempi kuin vuoden 2025 kalkkisen kiertäjäkalvosinvaivan suosituksessa.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text_author_article_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "SHOULDER-OPTIMA-ACUP", "document_id": "optima_shoulder", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Persistent shoulder pain: laser acupuncture", "condition_fi": "Pitkittynyt olkapääkipu: laserakupunktio", "direction": "may_consider", "strength_as_reported": "Clinicians may consider", "evidence_certainty_as_reported": "", "scope": "Shoulder pain >3 months", "summary_en": "May consider laser acupuncture for shoulder pain lasting more than 3 months.", "summary_fi": "Laserakupunktiota voidaan harkita yli kolme kuukautta kestäneeseen olkapääkipuun.", "locator": "Abstract recommendation d; persistent shoulder pain recommendation", "evidence_anchor": "laser acupuncture", "caveat_en": "Delivery method differs from tissue-directed laser; this is the same guideline as the shoulder LLLT row.", "caveat_fi": "Eri toteutustapa; sama asiakirja kuin olkapään LLLT-rivillä.", "intervention": "Laser acupuncture", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text_author_article_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "TMD-JAPAN", "document_id": "jstmj", "specialty": "Dentistry / orofacial pain", "condition_en": "Temporomandibular disorders", "condition_fi": "Purentaelimistön kipu ja toimintahäiriöt (TMD)", "direction": "may_consider", "strength_as_reported": "Conditional / weak; 2D", "evidence_certainty_as_reported": "Very low (abstract; Grade D)", "scope": "Primary treatment of TMD in general practice", "summary_en": "Conditionally recommends LLLT, with additional considerations, alongside the guideline's main primary care options.", "summary_fi": "LLLT saa ehdollisen suosituksen. Näytön varmuus arvioidaan hyvin matalaksi (2D).", "locator": "Abstract; sections 3.12–3.13; PDF pp. 1 and 6", "evidence_anchor": "LLLT be a conditional recommendation", "caveat_en": "The 2023 edition was published in English in 2025. Do not call it a strong recommendation.", "caveat_fi": "Vuoden 2023 suositus julkaistiin englanniksi 2025.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "TMD-BMJ", "document_id": "bmj_tmd", "specialty": "Dentistry / chronic pain", "condition_en": "Chronic TMD-associated pain", "condition_fi": "Krooninen TMD:hen liittyvä kipu", "direction": "against", "strength_as_reported": "Conditional recommendation against", "evidence_certainty_as_reported": "", "scope": "Chronic TMD-associated pain lasting ≥3 months", "summary_en": "Conditionally recommends against low-level laser alone or with co-interventions.", "summary_fi": "Matalatehoista laserhoitoa suositellaan ehdollisesti vastaan yksin tai muiden hoitojen kanssa kroonisessa TMD-kivussa.", "locator": "Abstract / Recommendations; conditional recommendations against", "evidence_anchor": "low level laser therapy (alone or in combination with other interventions)", "caveat_en": "Different recommendation from the Japanese guideline; chronic pain scope and methodology should remain explicit.", "caveat_fi": "Kanta poikkeaa japanilaisesta suosituksesta. Kohteena on vähintään kolme kuukautta kestänyt kipu.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-NICE", "document_id": "nice_oa", "specialty": "Musculoskeletal / primary care", "condition_en": "Osteoarthritis", "condition_fi": "Nivelrikko", "direction": "against", "strength_as_reported": "Do not offer", "evidence_certainty_as_reported": "Insufficient evidence of benefit", "scope": "People with osteoarthritis; electrotherapy modalities including laser", "summary_en": "Do not offer laser therapy because benefit evidence is insufficient.", "summary_fi": "Laserhoitoa ei suositella tarjottavaksi nivelrikkoon, koska hyödystä ei ole riittävää näyttöä.", "locator": "NG226 recommendation 1.3.9", "evidence_anchor": "Do not offer any of the following electrotherapy treatments", "caveat_en": "This is an explicit recommendation against offering, not merely an absence of a recommendation.", "caveat_fi": "Nimenomainen suositus olla tarjoamatta hoitoa.", "intervention": "Laser therapy (source terminology)", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-RACGP", "document_id": "racgp_oa", "specialty": "Musculoskeletal / primary care", "condition_en": "Knee and hip osteoarthritis", "condition_fi": "Polven ja lonkan nivelrikko", "direction": "against", "strength_as_reported": "Conditional against", "evidence_certainty_as_reported": "Low for knee laser; very low for hip laser", "scope": "Knee and/or hip osteoarthritis", "summary_en": "Suggests not offering laser electrotherapy for knee or hip osteoarthritis.", "summary_fi": "Laserhoitoa suositellaan ehdollisesti vastaan polven tai lonkan nivelrikossa.", "locator": "Summary recommendations; Other electrotherapy – Knee and/or hip; matching official web chapter", "evidence_anchor": "We suggest not offering electrotherapy modalities", "caveat_en": "The guideline's low and very low certainty categories depend on joint and modality; preserve these distinctions.", "caveat_fi": "Näytön luokka riippuu nivelestä: polven laser-näyttö low, lonkan very low.", "intervention": "Laser electrotherapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "DFU-IWGDF", "document_id": "iwgdf", "specialty": "Wound care / diabetes", "condition_en": "Diabetes-related foot ulcers", "condition_fi": "Diabetekseen liittyvät jalkahaavat", "direction": "against", "strength_as_reported": "Strong", "evidence_certainty_as_reported": "Low", "scope": "Physical therapies for wound healing, including light and laser; adjunct to standard care", "summary_en": "Do not use physical therapies, including light/laser, for healing diabetes-related foot ulcers.", "summary_fi": "Fysikaalisia hoitoja, mukaan lukien valo- ja laserhoidot, ei suositella diabetekseen liittyvien jalkahaavojen paranemisen edistämiseen.", "locator": "Recommendation 15; PDF p. 20 and rationale", "evidence_anchor": "Do not use any interventions reported in the field of physical therapies", "caveat_en": "This is a grouped physical-therapy recommendation; it is distinct from JAAD 2025 and WHS recommendations for other wound settings.", "caveat_fi": "Useita fysikaalisia hoitoja koskeva suositus; eri kanta kuin eräissä muiden potilasryhmien konsensuksissa.", "intervention": "Light and laser treatment within physical therapies", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "PU-WHS", "document_id": "whs_pressure", "specialty": "Wound care", "condition_en": "Pressure ulcers", "condition_fi": "Painehaavat", "direction": "may_consider", "strength_as_reported": "Guideline 7b.5; Level III", "evidence_certainty_as_reported": "Level III as reported by WHS", "scope": "Pressure ulcer healing in conjunction with traditional therapy", "summary_en": "Laser may improve pressure-ulcer healing when combined with traditional treatment.", "summary_fi": "Laserhoito saattaa edistää painehaavojen paranemista tavanomaisen hoidon lisänä.", "locator": "Guideline 7b.5 (new), Principle", "evidence_anchor": "Laser therapy may result in improvement in pressure ulcer healing", "caveat_en": "The guideline calls for further randomized research; Level III is its own system, not a GRADE label.", "caveat_fi": "Lisätutkimuksia tarvitaan. Level III on lähteen oma luokitus.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "TINNITUS-VA", "document_id": "va_tinnitus", "specialty": "Audiology / otolaryngology", "condition_en": "Tinnitus", "condition_fi": "Tinnitus", "direction": "against", "strength_as_reported": "Weak against", "evidence_certainty_as_reported": "", "scope": "Tinnitus management", "summary_en": "Suggests against low-level laser therapy for tinnitus.", "summary_fi": "Matalatehoista laserhoitoa suositellaan heikosti vastaan tinnituksen hoidossa.", "locator": "Recommendation 21; PDF pp. 36 and 71–72", "evidence_anchor": "We suggest against low-level laser therapy", "caveat_en": "Do not reinterpret Weak against as evidence in favor.", "caveat_fi": "Weak against tarkoittaa kielteistä suositusta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "TINNITUS-S3", "document_id": "s3_tinnitus", "specialty": "Audiology / otolaryngology", "condition_en": "Chronic tinnitus", "condition_fi": "Krooninen tinnitus", "direction": "against", "strength_as_reported": "Recommendation against; strong consensus (100%)", "evidence_certainty_as_reported": "2b; no evidence of efficacy (source's wording)", "scope": "Chronic tinnitus", "summary_en": "Low-level laser should not be practiced for chronic tinnitus.", "summary_fi": "Matalatehoista laserhoitoa ei suositella krooniseen tinnitukseen; konsensus oli 100 %.", "locator": "Section 4.1.8.7", "evidence_anchor": "Low-level laser therapy should not be practiced for chronic tinnitus", "caveat_en": "The 2021 German guideline is available as a 2022 English article.", "caveat_fi": "Saksalaisen suosituksen vuosiversio on 2021; englanninkielinen julkaisu 2022.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "AGA-S3", "document_id": "s3_aga", "specialty": "Dermatology / hair", "condition_en": "Androgenetic alopecia: adjunctive use", "condition_fi": "Androgeneettinen hiustenlähtö: lisähoito", "direction": "may_consider", "strength_as_reported": "Suggest / upward arrow", "evidence_certainty_as_reported": "Level of evidence 2", "scope": "Men and women with AGA; adjunctive LLLT using RCT-supported energy levels", "summary_en": "Suggests LLLT as adjunctive therapy using settings with demonstrated efficacy in randomized trials.", "summary_fi": "LLLT:tä ehdotetaan lisähoidoksi naisille ja miehille, kun käytetään satunnaistetuissa tutkimuksissa vaikuttaviksi osoitettuja energiatasoja.", "locator": "Section 3.6.7; PDF p. 40", "evidence_anchor": "We suggest using LLLT as ancillary therapy", "caveat_en": "The short version appeared in 2018; full guideline is the 2017 update.", "caveat_fi": "Täysi suositus on vuoden 2017 päivitys; lyhyt julkaisu ilmestyi 2018.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "AGA-S3-LONG", "document_id": "s3_aga", "specialty": "Dermatology / hair", "condition_en": "Androgenetic alopecia: use beyond 6 months", "condition_fi": "Androgeneettinen hiustenlähtö: yli 6 kuukauden käyttö", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation for or against", "evidence_certainty_as_reported": "", "scope": "LLLT treatment for AGA for more than 6 months", "summary_en": "Cannot recommend for or against treatment beyond 6 months.", "summary_fi": "Yli kuuden kuukauden käytöstä ei voida antaa suositusta puolesta tai vastaan.", "locator": "Section 3.6.7; PDF p. 40", "evidence_anchor": "We cannot make a recommendation for or against treatment for more than 6", "caveat_en": "Keep the long-term evidence gap next to the positive adjunctive-use recommendation.", "caveat_fi": "Pitkäaikaiskäytön epävarmuus säilytetään myönteisen lisähoitosuosituksen rinnalla.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "FI-NECK", "document_id": "fi_neck", "specialty": "Finnish clinical guideline", "condition_en": "Neck pain in adults", "condition_fi": "Aikuisten niskakipu", "direction": "insufficient_evidence", "strength_as_reported": "No explicit treatment-strength grade", "evidence_certainty_as_reported": "C (Käypä hoito evidence grade)", "scope": "Adults with neck pain", "summary_en": "States that reliable information on low-level laser effectiveness is lacking.", "summary_fi": "Matalatehoisen laserin vaikuttavuudesta niskakivun hoidossa ei ole luotettavaa tietoa.", "locator": "Fysikaaliset hoidot; linked evidence summary nak08828", "evidence_anchor": "Matalatehoisen laserin vaikuttavuudesta", "caveat_en": "Grade C rates evidence, not recommendation strength.", "caveat_fi": "C on näytönaste, ei suosituksen vahvuus.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text_and_evidence_summary", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "FI-TMD", "document_id": "fi_tmd", "specialty": "Finnish clinical guideline", "condition_en": "TMD-related muscle pain", "condition_fi": "TMD:hen liittyvä lihaskipu", "direction": "descriptive_support", "strength_as_reported": "Possible short-term benefit", "evidence_certainty_as_reported": "C (Käypä hoito evidence grade)", "scope": "TMD-related muscle pain; short-term follow-up", "summary_en": "Low-level laser may relieve TMD muscle pain in short-term follow-up.", "summary_fi": "Pienienergiainen laserhoito saattaa lievittää TMD-lihaskipua lyhytaikaisessa seurannassa.", "locator": "Fysioterapia; evidence summary nak08036", "evidence_anchor": "Laserhoito (pienienergiainen, low-level) saattaa lievittää", "caveat_en": "A cautious evidence statement; source page indicates the guideline is under revision.", "caveat_fi": "Varovainen näytönarvio. Suositus on lähdesivun mukaan päivityksessä.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text_and_evidence_summary", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "FI-RA", "document_id": "fi_ra", "specialty": "Finnish clinical guideline", "condition_en": "Rheumatoid arthritis: hand-joint symptoms", "condition_fi": "Nivelreuman käsiniveloireet", "direction": "descriptive_support", "strength_as_reported": "Possible benefit", "evidence_certainty_as_reported": "C (Käypä hoito evidence grade)", "scope": "Hand-joint symptoms in rheumatoid arthritis", "summary_en": "Laser may help hand-joint symptoms.", "summary_fi": "Laserhoito saattaa helpottaa käsiniveloireita nivelreumassa.", "locator": "Fysikaaliset hoidot; evidence summary nak08409", "evidence_anchor": "Laserhoito saattaa helpottaa käsiniveloireita", "caveat_en": "2022 guideline links a 2015 evidence summary. This does not establish disease-modifying efficacy.", "caveat_fi": "Vuoden 2022 suositus viittaa vuoden 2015 näytönarvioon. Kannanotto koskee oireita.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text_and_evidence_summary", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "FI-SHOULDER", "document_id": "fi_shoulder", "specialty": "Finnish clinical guideline", "condition_en": "Shoulder tendinopathy / impingement", "condition_fi": "Olkapään jännevaivat / pinneoireisto", "direction": "insufficient_evidence", "strength_as_reported": "No clear evidence of usefulness", "evidence_certainty_as_reported": "", "scope": "Shoulder impingement; electrical / laser physical modalities", "summary_en": "States that few randomized studies exist and no clear benefit is established for laser and other physical modalities.", "summary_fi": "Laserin ja muiden fysikaalisten laitehoitojen hyödyllisyydestä ei ole selvää näyttöä.", "locator": "Fysikaaliset hoidot", "evidence_anchor": "Mitään selvää näyttöä näiden hoitomuotojen hyödyllisyydestä ei ole", "caveat_en": "Main guideline text is an evidence statement, not a separately graded laser recommendation.", "caveat_fi": "Pääsuosituksen näytönarvio, ei erillinen luokiteltu laserhoitosuositus.", "intervention": "Laser among physical modalities", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "FI-LEGULCER", "document_id": "fi_legulcer", "specialty": "Finnish clinical guideline", "condition_en": "Chronic leg ulcers", "condition_fi": "Krooninen alaraajahaava", "direction": "insufficient_evidence", "strength_as_reported": "Further research needed", "evidence_certainty_as_reported": "", "scope": "Chronic leg ulcers; low-dose laser and other adjunctive therapies", "summary_en": "Calls for additional research on the effectiveness of low-dose laser.", "summary_fi": "Pieniannoksisen laserhoidon tehosta krooniseen alaraajahaavaan tarvitaan lisää tutkimuksia.", "locator": "Muut paikallishoidot / adjunctive treatments", "evidence_anchor": "pieniannoksisen laserhoidon", "caveat_en": "The D grade nearby in the text refers to PRP, not laser; no laser-specific grade is assigned here.", "caveat_fi": "Tekstissä lähellä oleva D-luokitus koskee PRP:tä, ei laseria.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "AMD-AAO-MENTION", "document_id": "aao_amd", "specialty": "Ophthalmology", "condition_en": "Non-neovascular age-related macular degeneration", "condition_fi": "Ei-uudissuonittava silmänpohjan ikärappeuma", "direction": "mention_only", "strength_as_reported": "No recommendation strength verified", "evidence_certainty_as_reported": "", "scope": "AAO PPP 2024 treatment section; official December 2025 clarification about a device", "summary_en": "The official update note confirms a mention of multiwavelength PBM and the FDA's 2024 de novo authorization of Valeda.", "summary_fi": "AAO:n virallinen päivityshuomautus vahvistaa PBM-maininnan ja Valeda-laitteen FDA:n de novo -luvan kuvauksen.", "locator": "Official update note, December 2025; refers to PPP p. 21", "evidence_anchor": "multiwavelength photobiomodulation", "caveat_en": "Only the official update note was read. A PBM treatment recommendation cannot be inferred from a device-authorization statement.", "caveat_fi": "Luettu virallinen päivityshuomautus. Laitelupaa koskevasta maininnasta ei päätellä myönteistä hoitosuositusta.", "intervention": "Device-specific multiwavelength photobiomodulation", "historical": false, "checked_on": "2026-10-15", "verification_depth": "official_update_note_only", "final_grade_recheck_needed": false, "recommendation_class": "guideline_update_note" }, { "id": "JAAD-NEUROPATHY", "document_id": "jaad_consensus", "specialty": "Dermatology / multidisciplinary consensus", "condition_en": "Peripheral neuropathy", "condition_fi": "Perifeerinen neuropatia", "direction": "descriptive_support", "strength_as_reported": "Expert-panel consensus; no indication-specific strength verified", "evidence_certainty_as_reported": "", "scope": "Adult medical / dermatologic applications as stated in the abstract", "summary_en": "The expert consensus identifies PBM as an effective treatment option for peripheral neuropathy.", "summary_fi": "Asiantuntijakonsensus pitää PBM:ää mahdollisesti käyttökelpoisena hoitovaihtoehtona tähän käyttöaiheeseen.", "locator": "Abstract, Results", "evidence_anchor": "peripheral neuropathy", "caveat_en": "Condition and cause of neuropathy are not specified in the abstract. Published in JAAD; no AAD organizational endorsement verified.", "caveat_fi": "Abstrakti ei rajaa neuropatian syytä. Julkaistu JAAD:ssa; AAD-järjestön hyväksyntää ei vahvistettu.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "abstract_and_author_repository_abstract", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "JAAD-AGA", "document_id": "jaad_consensus", "specialty": "Dermatology / multidisciplinary consensus", "condition_en": "Androgenic alopecia", "condition_fi": "Androgeneettinen hiustenlähtö", "direction": "descriptive_support", "strength_as_reported": "Expert-panel consensus; no indication-specific strength verified", "evidence_certainty_as_reported": "", "scope": "Adult medical / dermatologic applications as stated in the abstract", "summary_en": "The expert consensus identifies PBM as an effective treatment option for androgenic alopecia.", "summary_fi": "Asiantuntijakonsensus pitää PBM:ää mahdollisesti käyttökelpoisena hoitovaihtoehtona tähän käyttöaiheeseen.", "locator": "Abstract, Results", "evidence_anchor": "androgenic alopecia", "caveat_en": " Published in JAAD; no AAD organizational endorsement verified.", "caveat_fi": " Julkaistu JAAD:ssa; AAD-järjestön hyväksyntää ei vahvistettu.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "abstract_and_author_repository_abstract", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "JAAD-WOUNDS", "document_id": "jaad_consensus", "specialty": "Dermatology / multidisciplinary consensus", "condition_en": "Wound ulcers of multiple etiologies", "condition_fi": "Eri syistä johtuvat haavaumat", "direction": "descriptive_support", "strength_as_reported": "Expert-panel consensus; no indication-specific strength verified", "evidence_certainty_as_reported": "", "scope": "Adult medical / dermatologic applications as stated in the abstract", "summary_en": "The expert consensus identifies PBM as an effective treatment option for wound ulcers of multiple etiologies.", "summary_fi": "Asiantuntijakonsensus pitää PBM:ää mahdollisesti käyttökelpoisena hoitovaihtoehtona tähän käyttöaiheeseen.", "locator": "Abstract, Results", "evidence_anchor": "wound ulcers due to multiple etiologies", "caveat_en": "Abstract-level broad wording; no indication-specific protocol or certainty grade verified. Published in JAAD; no AAD organizational endorsement verified.", "caveat_fi": "Abstraktin laaja arvio; yksittäisten haavatyyppien protokollia tai näyttöluokkia ei vahvistettu. Julkaistu JAAD:ssa; AAD-järjestön hyväksyntää ei vahvistettu.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "abstract_and_author_repository_abstract", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "JAAD-PRESSURE", "document_id": "jaad_consensus", "specialty": "Dermatology / multidisciplinary consensus", "condition_en": "Decubitus / pressure ulcers", "condition_fi": "Painehaavat", "direction": "descriptive_support", "strength_as_reported": "Expert-panel consensus; no indication-specific strength verified", "evidence_certainty_as_reported": "", "scope": "Adult medical / dermatologic applications as stated in the abstract", "summary_en": "The expert consensus identifies PBM as an effective treatment option for decubitus / pressure ulcers.", "summary_fi": "Asiantuntijakonsensus pitää PBM:ää mahdollisesti käyttökelpoisena hoitovaihtoehtona tähän käyttöaiheeseen.", "locator": "Abstract, Results", "evidence_anchor": "decubitus ulcers", "caveat_en": " Published in JAAD; no AAD organizational endorsement verified.", "caveat_fi": " Julkaistu JAAD:ssa; AAD-järjestön hyväksyntää ei vahvistettu.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "abstract_and_author_repository_abstract", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "JAAD-DFU-PAIN", "document_id": "jaad_consensus", "specialty": "Dermatology / multidisciplinary consensus", "condition_en": "Pain attributed to diabetic foot ulcers", "condition_fi": "Diabeettisten jalkahaavojen kipu", "direction": "descriptive_support", "strength_as_reported": "Expert-panel consensus; no indication-specific strength verified", "evidence_certainty_as_reported": "", "scope": "Adult medical / dermatologic applications as stated in the abstract", "summary_en": "The expert consensus identifies PBM as an effective treatment option for pain attributed to diabetic foot ulcers.", "summary_fi": "Asiantuntijakonsensus pitää PBM:ää mahdollisesti käyttökelpoisena hoitovaihtoehtona tähän käyttöaiheeseen.", "locator": "Abstract, Results", "evidence_anchor": "pain attributed to diabetic foot ulcers", "caveat_en": "This is a pain claim, not a verified claim that diabetic foot ulcers heal faster; keep separate from IWGDF's wound-healing recommendation. Published in JAAD; no AAD organizational endorsement verified.", "caveat_fi": "Arvio koskee kipua, ei haavan paranemisnopeutta. Eri tulosmuuttuja kuin IWGDF-suosituksessa. Julkaistu JAAD:ssa; AAD-järjestön hyväksyntää ei vahvistettu.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "abstract_and_author_repository_abstract", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "JAAD-RADIATION", "document_id": "jaad_consensus", "specialty": "Dermatology / multidisciplinary consensus", "condition_en": "Acute radiation dermatitis", "condition_fi": "Akuutti sädeihottuma", "direction": "descriptive_support", "strength_as_reported": "Expert-panel consensus; no indication-specific strength verified", "evidence_certainty_as_reported": "", "scope": "Adult medical / dermatologic applications as stated in the abstract", "summary_en": "The expert consensus identifies PBM as an effective treatment option for acute radiation dermatitis.", "summary_fi": "Asiantuntijakonsensus pitää PBM:ää mahdollisesti käyttökelpoisena hoitovaihtoehtona tähän käyttöaiheeseen.", "locator": "Abstract, Results", "evidence_anchor": "acute radiation dermatitis", "caveat_en": "Abstract does not distinguish prevention from treatment or specify the cancer site. Published in JAAD; no AAD organizational endorsement verified.", "caveat_fi": "Abstrakti ei erottele ehkäisyä ja hoitoa eikä syövän sijaintia. Julkaistu JAAD:ssa; AAD-järjestön hyväksyntää ei vahvistettu.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "abstract_and_author_repository_abstract", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "CHINA-ACNE", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Acne vulgaris", "condition_fi": "Tavallinen akne", "direction": "recommended", "strength_as_reported": "Strong", "evidence_certainty_as_reported": "High-quality", "scope": "Acne; monotherapy or adjunct according to Question 6", "summary_en": "PBM is recommended for acne; the panel reports strong recommendation and high-quality evidence.", "summary_fi": "PBM-hoitoa suositellaan akneen; paneelin oma luokitus on vahva suositus ja korkealaatuinen näyttö.", "locator": "Table 2 and Question 6", "evidence_anchor": "Acne vulgaris", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-REJUVENATION", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Skin rejuvenation / photoaging", "condition_fi": "Ihon valovanheneminen ja ihon uudistaminen", "direction": "recommended", "strength_as_reported": "Strong", "evidence_certainty_as_reported": "Moderate-quality", "scope": "Skin rejuvenation and photoaging", "summary_en": "Recommends PBM for skin rejuvenation / photoaging.", "summary_fi": "PBM-hoitoa suositellaan ihon uudistamiseen ja valovanhenemiseen.", "locator": "Table 2 and Question 7", "evidence_anchor": "Skin rejuvenation", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-WOUNDS", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Wound healing and ulcers", "condition_fi": "Haavojen ja haavaumien paraneminen", "direction": "recommended", "strength_as_reported": "Strong", "evidence_certainty_as_reported": "Moderate-quality", "scope": "Wound healing / ulcers; adjunctive dermatologic protocols", "summary_en": "Recommends PBM for wound healing and ulcers under the panel's protocols.", "summary_fi": "PBM-hoitoa suositellaan haavojen ja haavaumien paranemisen tukemiseen paneelin protokollien mukaan.", "locator": "Table 2 and Question 8", "evidence_anchor": "Wound healing and ulcers", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-SCARS", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Scars", "condition_fi": "Arvet", "direction": "recommended", "strength_as_reported": "Strong", "evidence_certainty_as_reported": "Moderate-quality", "scope": "Scar management", "summary_en": "Recommends PBM for scar management.", "summary_fi": "PBM-hoitoa suositellaan arpien hoitoon.", "locator": "Table 2 and Question 9", "evidence_anchor": "Scar", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-AGA", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Androgenetic alopecia", "condition_fi": "Androgeneettinen hiustenlähtö", "direction": "recommended", "strength_as_reported": "Strong", "evidence_certainty_as_reported": "High-quality", "scope": "AGA; first-line or adjunctive use within consensus", "summary_en": "Recommends PBM as a first-line or adjunctive option for AGA.", "summary_fi": "PBM-hoitoa suositellaan androgeneettiseen hiustenlähtöön ensilinjan vaihtoehtona tai lisähoitona.", "locator": "Table 2 and Question 10", "evidence_anchor": "Androgenetic alopecia", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-AA", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Alopecia areata", "condition_fi": "Pälvikalju", "direction": "may_consider", "strength_as_reported": "Weak", "evidence_certainty_as_reported": "Moderate-quality", "scope": "Alopecia areata", "summary_en": "Offers a weak recommendation for PBM in alopecia areata.", "summary_fi": "PBM saa heikon suosituksen pälvikaljun hoidossa.", "locator": "Table 2 and Question 10", "evidence_anchor": "Alopecia areata", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-SCARRING", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Scarring alopecias: FFA, LPP, CCCA", "condition_fi": "Arpeuttavat hiustenlähtösairaudet: FFA, LPP ja CCCA", "direction": "may_consider", "strength_as_reported": "Weak", "evidence_certainty_as_reported": "Low/very low-quality", "scope": "Frontal fibrosing alopecia; lichen planopilaris; central centrifugal cicatricial alopecia", "summary_en": "Offers a weak recommendation for selected scarring alopecias.", "summary_fi": "PBM saa heikon suosituksen eräisiin arpeuttaviin hiustenlähtösairauksiin.", "locator": "Table 2 and Question 10", "evidence_anchor": "Frontal fibrosing alopecia", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-VIRAL", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Viral skin infections (including herpes)", "condition_fi": "Virusperäiset ihoinfektiot, kuten herpes", "direction": "recommended", "strength_as_reported": "Strong", "evidence_certainty_as_reported": "High-quality", "scope": "Viral skin infections; condition-specific regimens in Question 11", "summary_en": "Recommends PBM for selected viral skin infections including herpes, with condition-specific regimens.", "summary_fi": "PBM-hoitoa suositellaan eräiden virusperäisten ihoinfektioiden, kuten herpeksen, hoitoon käyttöaihekohtaisin protokollin.", "locator": "Table 2 and Question 11", "evidence_anchor": "Viral skin infections", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-CANCER", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Cancer therapy-associated oral mucositis and acute radiation dermatitis", "condition_fi": "Syöpähoitojen mukosiitti ja akuutti sädeihottuma", "direction": "recommended", "strength_as_reported": "Strong", "evidence_certainty_as_reported": "High-quality", "scope": "Prevention and treatment of oral mucositis and acute radiation dermatitis", "summary_en": "Recommends PBM for prevention and treatment of these cancer-therapy toxicities.", "summary_fi": "PBM-hoitoa suositellaan suun mukosiitin ja akuutin sädeihottuman ehkäisyyn ja hoitoon.", "locator": "Table 2 and Question 12", "evidence_anchor": "Conditions secondary to cancer therapies", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "CHINA-OTHER", "document_id": "china_dermatology", "specialty": "Dermatology / Chinese expert consensus", "condition_en": "Melasma, psoriasis, rosacea, sensitive skin, atopic dermatitis, vitiligo", "condition_fi": "Melasma, psoriaasi, ruusufinni, herkkä iho, atooppinen ihottuma ja vitiligo", "direction": "may_consider", "strength_as_reported": "Weak", "evidence_certainty_as_reported": "Low/very low-quality", "scope": "Adjunctive PBM for selected other dermatologic conditions; individualized protocols", "summary_en": "Offers weak recommendations for selected other skin conditions, with low or very low evidence.", "summary_fi": "PBM:ää voidaan harkita lisähoidoksi eräissä muissa ihosairauksissa; suositus on heikko ja näyttö matalaa tai hyvin matalaa.", "locator": "Table 2 and Question 13", "evidence_anchor": "Melasma, psoriasis", "caveat_en": "These are the Chinese panel's published classifications, not a new independent certainty assessment or a universal consensus.", "caveat_fi": "Luokitukset ovat kiinalaisen asiantuntijapaneelin omia arvioita; ne eivät ole tämän koonnin riippumaton näytönarvio.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "WALT22-OM", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Oral mucositis: prevention and treatment protocols", "condition_fi": "Suun mukosiitin ehkäisy- ja hoitoprotokollat", "direction": "recommended", "strength_as_reported": "Section labelled clinical practice guidelines", "evidence_certainty_as_reported": "", "scope": "Cancer therapy-associated oral mucositis; intraoral and transcutaneous delivery protocols", "summary_en": "The mucositis section gives PBM prevention and treatment protocols and is explicitly labelled clinical practice guidelines; the strongest contextual evidence concerns prevention in specified cancer regimens.", "summary_fi": "Mukosiittiosio esittää suunsisäisiä ja ihon läpi toteutettavia ehkäisy- ja hoitoprotokollia, ja se on nimetty hoitosuositusosioksi.", "locator": "Section 3.3.1.1; Table 1", "evidence_anchor": "WALT recommendation 2022: clinical practice guidelines", "caveat_en": "This position paper builds partly on MASCC/ISOO; do not count it as independent trial evidence. Keep prevention and treatment populations distinct.", "caveat_fi": "Kannattaa huomioida yhteys MASCC/ISOO-lähteisiin sekä ehkäisyn ja hoidon potilasryhmäkohtaiset erot.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-XERO", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Xerostomia and hyposalivation", "condition_fi": "Suun kuivuus ja vähentynyt syljeneritys", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated xerostomia and hyposalivation", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.2.1", "evidence_anchor": "Xerostomia and hyposalivation", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-DYSPHAGIA", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Acute dysphagia", "condition_fi": "Akuutti nielemisvaikeus", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated acute dysphagia", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.3.1", "evidence_anchor": "Acute dysphagia", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-DERMATITIS", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Acute radiation dermatitis", "condition_fi": "Akuutti sädeihottuma", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated acute radiation dermatitis", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.4.1", "evidence_anchor": "Acute radiation dermatitis", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-LYMPH", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Lymphedema", "condition_fi": "Lymfaturvotus", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated lymphedema", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.5.1", "evidence_anchor": "Lymphedema", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-TASTE", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Dysgeusia", "condition_fi": "Makuaistin häiriö", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated dysgeusia", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.6.1", "evidence_anchor": "Dysgeusia", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-TRISMUS", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Trismus", "condition_fi": "Suun avausrajoitus (trismus)", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated trismus", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.7.1", "evidence_anchor": "Trismus", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-BONE", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Bone necrosis associated with cancer therapy", "condition_fi": "Syöpähoitoihin liittyvä luunekroosi", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated bone necrosis associated with cancer therapy", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.8.1", "evidence_anchor": "Bone necrosis", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-VOICE", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Voice and speech alterations", "condition_fi": "Äänen ja puheen muutokset", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated voice and speech alterations", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.9.1", "evidence_anchor": "Voice and speech alterations", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-HFS", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Palmar-plantar erythrodysesthesia / hand-foot syndrome", "condition_fi": "Käsi–jalkaoireyhtymä", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated palmar-plantar erythrodysesthesia / hand-foot syndrome", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.10.1", "evidence_anchor": "Palmar-Plantar", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-GVHD", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Graft-versus-host disease", "condition_fi": "Käänteishyljintäsairaus (GVHD)", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated graft-versus-host disease", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.11.1", "evidence_anchor": "Graft-versus-Host", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-CIPN", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Cancer therapy-associated peripheral neuropathy", "condition_fi": "Syöpähoitoihin liittyvä perifeerinen neuropatia", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated cancer therapy-associated peripheral neuropathy", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.12.1", "evidence_anchor": "peripheral neuropathy", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-FIBROSIS", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Radiation-induced fibrosis", "condition_fi": "Sädehoidon aiheuttama fibroosi", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated radiation-induced fibrosis", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.13.1", "evidence_anchor": "radiation-induced fibrosis", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT22-ALOPECIA", "document_id": "walt_2022", "specialty": "Oncology / PBM position paper", "condition_en": "Chemotherapy-induced alopecia", "condition_fi": "Solunsalpaajahoidon aiheuttama hiustenlähtö", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "Insufficient data for clinical treatment guidelines (explicit statement)", "scope": "Cancer therapy-associated chemotherapy-induced alopecia", "summary_en": "Proposes technical PBM parameters as expert consensus while explicitly stating that data are inadequate to provide clinical treatment guidelines.", "summary_fi": "Esittää teknisiä PBM-protokollaehdotuksia asiantuntijakonsensuksena. Asiakirjan mukaan näyttö ei riitä varsinaiseen kliiniseen hoitosuositukseen.", "locator": "Section 3.3.14.1", "evidence_anchor": "chemotherapy-induced alopecia", "caveat_en": "A technical expert protocol is not a formal graded endorsement; the same explicit evidence limitation appears in each of these sections.", "caveat_fi": "Tekninen protokollaehdotus erotetaan varsinaisesta hoitosuosituksesta.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT26-BMS", "document_id": "walt_orofacial", "specialty": "Orofacial pain / PBM position paper", "condition_en": "Primary burning mouth syndrome", "condition_fi": "Primaarinen suupolteoireyhtymä", "direction": "recommended", "strength_as_reported": "WALT clinical practice guidelines", "evidence_certainty_as_reported": "LoE I (authors' classification)", "scope": "Neuropathic pain in primary burning mouth syndrome", "summary_en": "Provides WALT clinical practice guidance supporting PBM for primary BMS.", "summary_fi": "WALT esittää PBM-hoitoa tukevan hoitosuosituksen primaariseen suupolteoireyhtymään; tekijöiden luokitus on LoE I.", "locator": "Section 4.3.1; Table 4", "evidence_anchor": "WALT Recommendation: Clinical Practice Guidelines", "caveat_en": "The rating belongs to this WALT paper; it is not a cross-society consensus or an independently regraded result.", "caveat_fi": "LoE I on WALT-julkaisun oma luokitus.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT26-TN", "document_id": "walt_orofacial", "specialty": "Orofacial pain / PBM position paper", "condition_en": "Idiopathic trigeminal neuralgia", "condition_fi": "Idiopaattinen kolmoishermosärky", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "LoE II (authors' classification)", "scope": "Idiopathic trigeminal neuralgia", "summary_en": "Provides expert consensus PBM guidance, rather than the paper's BMS-level clinical practice guideline.", "summary_fi": "Esittää PBM-hoidon asiantuntijakonsensuksen idiopaattiseen kolmoishermosärkyyn; luokitus on LoE II.", "locator": "Section 4.3.2; Table 6", "evidence_anchor": "idiopathic TN", "caveat_en": "Distinct recommendation category from BMS within the same paper.", "caveat_fi": "Eri suositusluokka kuin saman julkaisun suupolteoireyhtymässä.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT26-PHN", "document_id": "walt_orofacial", "specialty": "Orofacial pain / PBM position paper", "condition_en": "Post-herpetic neuralgia", "condition_fi": "Vyöruusun jälkeinen hermosärky", "direction": "expert_protocol", "strength_as_reported": "Expert consensus opinion", "evidence_certainty_as_reported": "LoE II (authors' classification)", "scope": "Post-herpetic neuralgia within the paper's orofacial neuropathic-pain scope", "summary_en": "Provides expert consensus PBM guidance for post-herpetic neuralgia.", "summary_fi": "Esittää PBM-hoidon asiantuntijakonsensuksen vyöruusun jälkeiseen hermosärkyyn; luokitus on LoE II.", "locator": "Section 4.3.3; Table 8", "evidence_anchor": "Post-Herpetic Neuralgia", "caveat_en": "Keep the paper's orofacial scope; do not generalize to every neuropathic pain disorder.", "caveat_fi": "Säilytä julkaisun kasvojen ja suun alueen kipua koskeva rajaus.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT26-PTTN", "document_id": "walt_orofacial", "specialty": "Orofacial pain / PBM position paper", "condition_en": "Post-traumatic trigeminal neuropathic pain", "condition_fi": "Trauman jälkeinen kolmoishermon neuropaattinen kipu", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation possible", "evidence_certainty_as_reported": "", "scope": "Condition-specific PBM use", "summary_en": "Insufficient condition-specific clinical evidence prevents a WALT recommendation.", "summary_fi": "Käyttöaihekohtaista kliinistä näyttöä ei ole riittävästi WALT-suosituksen antamiseen.", "locator": "Section 4.3.4", "evidence_anchor": "Post-Traumatic Trigeminal", "caveat_en": "Neither absence of a recommendation nor a PBM position paper title constitutes an endorsement.", "caveat_fi": "Näyttö ei riitä hoitosuositukseen.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT26-GPN", "document_id": "walt_orofacial", "specialty": "Orofacial pain / PBM position paper", "condition_en": "Glossopharyngeal neuralgia", "condition_fi": "Kieli-kitahermon neuralgia", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation possible", "evidence_certainty_as_reported": "", "scope": "Condition-specific PBM use", "summary_en": "Insufficient condition-specific clinical evidence prevents a WALT recommendation.", "summary_fi": "Käyttöaihekohtaista kliinistä näyttöä ei ole riittävästi WALT-suosituksen antamiseen.", "locator": "Section 4.3.5", "evidence_anchor": "Glossopharyngeal", "caveat_en": "Neither absence of a recommendation nor a PBM position paper title constitutes an endorsement.", "caveat_fi": "Näyttö ei riitä hoitosuositukseen.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "WALT26-ON", "document_id": "walt_orofacial", "specialty": "Orofacial pain / PBM position paper", "condition_en": "Occipital neuralgia", "condition_fi": "Takaraivohermon neuralgia", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation possible", "evidence_certainty_as_reported": "", "scope": "Condition-specific PBM use", "summary_en": "Insufficient condition-specific clinical evidence prevents a WALT recommendation.", "summary_fi": "Käyttöaihekohtaista kliinistä näyttöä ei ole riittävästi WALT-suosituksen antamiseen.", "locator": "Section 4.3.5", "evidence_anchor": "Occipital", "caveat_en": "Neither absence of a recommendation nor a PBM position paper title constitutes an endorsement.", "caveat_fi": "Näyttö ei riitä hoitosuositukseen.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "RD-MASCC-HNC-PREVENT", "document_id": "mascc_dermatitis", "specialty": "Oncology / dermatology", "condition_en": "Acute radiation dermatitis prevention: head and neck cancer", "condition_fi": "Akuutin sädeihottuman ehkäisy pään ja kaulan syövässä", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation due to lack of consensus; 9/34 (26%) recommend", "evidence_certainty_as_reported": "", "scope": "Head and neck cancer; prevention of acute radiation dermatitis", "summary_en": "The panel could not make a recommendation for PBM to prevent acute radiation dermatitis in head and neck cancer because consensus was not achieved.", "summary_fi": "Pään ja kaulan syövän sädeihottuman ehkäisystä ei saavutettu riittävää konsensusta suosituksen antamiseen.", "locator": "Table 1, PDF p. 6, Laser therapy", "evidence_anchor": "Photobiomodulation or low-level laser therapy for head and neck cancer", "caveat_en": "Do not extend the positive breast-cancer prevention recommendation to head and neck cancer.", "caveat_fi": "Rintasyövän myönteistä ehkäisysuositusta ei laajenneta tähän potilasryhmään.", "intervention": "PBM / low-level laser therapy", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LYMPH-SIO-ASCO", "document_id": "sio_asco_breast", "specialty": "Oncologic rehabilitation", "condition_en": "Breast cancer-related lymphedema", "condition_fi": "Rintasyöpään liittyvä lymfaturvotus", "direction": "may_consider", "strength_as_reported": "C", "evidence_certainty_as_reported": "", "scope": "During and after breast cancer treatment; lymphedema", "summary_en": "The ASCO-endorsed SIO guideline states that low-level laser may be considered for improving lymphedema.", "summary_fi": "ASCO:n hyväksymä SIO-suositus sallii matalatehoisen laserin harkitsemisen lymfaturvotuksen hoitoon.", "locator": "Lymphedema recommendation", "evidence_anchor": "Low-level laser therapy, manual lymphatic drainage, and compression bandaging can be considered", "caveat_en": "One recommendation family: SIO 2017 with ASCO endorsement 2018. No claim of a strong recommendation.", "caveat_fi": "SIO 2017 ja ASCO:n hyväksyntä 2018 ovat samaa suositusperhettä; luokka C.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-CHINA-PEDIATRIC", "document_id": "china_om_consensus", "specialty": "Pediatric oncology", "condition_en": "Pediatric oral mucositis prevention and control", "condition_fi": "Lasten suun mukosiitin ehkäisy ja hallinta", "direction": "descriptive_support", "strength_as_reported": "Expert consensus; no laser-specific formal grade verified", "evidence_certainty_as_reported": "", "scope": "Pediatric HSCT, high-dose radiochemotherapy or radiochemotherapy for head and neck tumors", "summary_en": "The consensus describes LLLT as beneficial for preventing and controlling severe oral mucositis in these pediatric settings.", "summary_fi": "Konsensus kuvaa LLLT:n hyödylliseksi vaikean mukosiitin ehkäisyssä ja hallinnassa mainituissa lasten syöpähoitotilanteissa.", "locator": "Photobiotherapy prevention section", "evidence_anchor": "For pediatric patients undergoing HSCT", "caveat_en": "The source's broad pediatric wording is retained; it is not substituted for POGO's narrower formally stated settings.", "caveat_fi": "Lähteen laaja lasten potilasryhmärajaus säilytetään erillään POGO:n täsmällisistä suosituksista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "OM-CHINA-HNC", "document_id": "china_om_consensus", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention: head and neck chemoradiotherapy", "condition_fi": "Suun mukosiitin ehkäisy pään ja kaulan kemosädehoidossa", "direction": "descriptive_support", "strength_as_reported": "Expert consensus; no laser-specific formal grade verified", "evidence_certainty_as_reported": "", "scope": "Head and neck cancer receiving chemoradiotherapy; prevention", "summary_en": "Discusses a preventive role for LLLT, noting generally supportive but inconsistent studies and protocol limitations.", "summary_fi": "Kuvaa LLLT:n mahdollista ehkäisevää roolia pään ja kaulan kemosädehoidossa; tutkimukset ja hoitoprotokollat vaihtelevat.", "locator": "Photobiotherapy prevention section", "evidence_anchor": "LLLT has also been proposed to have a role in preventing OM", "caveat_en": "No universal device or dose endorsement is inferred from the narrative.", "caveat_fi": "Kuvailevasta tekstistä ei johdeta yleistä laite- tai annossuositusta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "PFP-APTA", "document_id": "apta_pfp", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Patellofemoral pain", "condition_fi": "Patellofemoraalinen kipu", "direction": "against", "strength_as_reported": "B (grouped biophysical-agent recommendation)", "evidence_certainty_as_reported": "", "scope": "Patients with patellofemoral pain; therapeutic laser among biophysical agents", "summary_en": "Advises against biophysical agents, including therapeutic laser, for patellofemoral pain.", "summary_fi": "Terapeuttista laseria ja muita mainittuja fysikaalisia laitehoitoja ei suositella patellofemoraalisen kivun hoitoon.", "locator": "PDF pp. 3 and 42; Interventions – Biophysical agents", "evidence_anchor": "Clinicians should not use biophysical agents", "caveat_en": "The B grade applies to the grouped recommendation; laser-specific high certainty is not inferred.", "caveat_fi": "B koskee useita fysikaalisia hoitoja kattavaa suositusta.", "intervention": "Therapeutic laser within grouped biophysical agents", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-KNGF", "document_id": "kngf_neck", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Nonspecific neck pain, grades I–III", "condition_fi": "Epäspesifi niskakipu, luokat I–III", "direction": "against", "strength_as_reported": "Not recommended (grouped recommendation)", "evidence_certainty_as_reported": "Low-quality evidence (grouped interventions)", "scope": "Neck pain grades I, II and III", "summary_en": "Advises against low-level laser for neck pain grades I–III.", "summary_fi": "Matalatehoista laseria ei suositella luokkien I–III niskakipuun.", "locator": "Published article PDF pp. 6–7; treatment recommendations", "evidence_anchor": "It is not recommended that clinicians use dry needling, low-level laser", "caveat_en": "Different from the APTA 2017 recommendations. Low-quality rating is attached to the grouped intervention recommendation.", "caveat_fi": "Kanta poikkeaa APTA:n vuoden 2017 suosituksesta; näytön luokka koskee yhdistettyä hoitoluetteloa.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RA-KNGF", "document_id": "kngf_ra", "specialty": "Rheumatology / rehabilitation", "condition_en": "Rheumatoid arthritis", "condition_fi": "Nivelreuma", "direction": "against", "strength_as_reported": "Do not offer; strongly discouraged in rationale", "evidence_certainty_as_reported": "Very low (non-exercise interventions assessed)", "scope": "Patients with rheumatoid arthritis; non-exercise physiotherapy", "summary_en": "Recommends not offering low-power laser and other listed non-exercise interventions.", "summary_fi": "Pienitehoista laseria ja muita lueteltuja ei-harjoittelullisia fysioterapiahoitoja ei suositella nivelreumaan.", "locator": "PDF p. 17, C.4; explanatory note 21, PDF p. 36", "evidence_anchor": "laagvermogen lasertherapie", "caveat_en": "The very-low evidence rating concerns the reviewed non-exercise interventions; do not call it evidence of harm.", "caveat_fi": "Hyvin matala näyttöluokka ei tarkoita osoitettua haittaa.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-KNGF", "document_id": "kngf_oa", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Hip or knee osteoarthritis", "condition_fi": "Lonkan tai polven nivelrikko", "direction": "against", "strength_as_reported": "Do not offer; strongly discouraged", "evidence_certainty_as_reported": "Very low (knee evidence); effect in hip OA unknown", "scope": "Hip/knee OA; improving physical function", "summary_en": "Recommends not offering LLLT, despite acknowledging a possible small adjunctive function effect in very-low-certainty knee evidence.", "summary_fi": "LLLT:tä ei suositella lonkan tai polven nivelrikkoon. Teksti huomioi mahdollisen pienen lisähyödyn polven toimintakykyyn, mutta pitää näyttöä hyvin epävarmana.", "locator": "Explanatory note 26; PDF pp. 49–50", "evidence_anchor": "Bied geen behandeling met low level laser therapie", "caveat_en": "Preserve the unfavorable recommendation alongside the source's qualified favorable evidence signal.", "caveat_fi": "Mahdollinen pieni tutkimushyöty ja kielteinen hoitosuositus esitetään rinnakkain.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-DEGAM", "document_id": "german_neck", "specialty": "Musculoskeletal / primary care", "condition_en": "Nonspecific neck pain", "condition_fi": "Epäspesifi niskakipu", "direction": "against", "strength_as_reported": "B; 100% consensus", "evidence_certainty_as_reported": "Evidence grade 2 (source framework)", "scope": "Acute or chronic nonspecific neck pain", "summary_en": "Laser therapy should not be used for nonspecific neck pain.", "summary_fi": "Laserhoitoa ei suositella epäspesifiin niskakipuun; suositus B ja konsensus 100 %.", "locator": "Recommendation 29; printed p. 42", "evidence_anchor": "Lasertherapie sollte zur Behandlung nicht-spezifischer", "caveat_en": "The guideline evaluates laser broadly and discusses both evidence limitations and active-care goals.", "caveat_fi": "Suositus arvioi laserhoitoa yleisesti ja painottaa myös aktiivista hoitoa.", "intervention": "Laser therapy (LLLT / HILT evidence discussed)", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-GERMAN-NVL", "document_id": "german_back", "specialty": "Musculoskeletal / primary care", "condition_en": "Nonspecific low back pain", "condition_fi": "Epäspesifi alaselkäkipu", "direction": "against", "strength_as_reported": "Strong against (double downward arrow)", "evidence_certainty_as_reported": "", "scope": "Acute and chronic nonspecific low back pain", "summary_en": "Recommends against laser therapy for nonspecific low back pain.", "summary_fi": "Laserhoitoa ei suositella epäspesifiin alaselkäkipuun.", "locator": "Recommendation 5-14; PDF p. 45 / printed p. 44", "evidence_anchor": "Lasertherapie soll zur Behandlung nicht-spezifischer", "caveat_en": "Historical 2017 wording; current validity is not established by this collection.", "caveat_fi": "Vuoden 2017 historiallinen suositusteksti; nykyistä voimassaoloa ei vahvistettu.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": true, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "S3-SUPPORT-CHEMO-PREV", "document_id": "german_supportive", "specialty": "Oncology / supportive care", "condition_en": "Oral mucositis prevention during chemotherapy", "condition_fi": "Suun mukosiitin ehkäisy solunsalpaajahoidossa", "direction": "insufficient_evidence", "strength_as_reported": "Evidence-based statement; strong consensus", "evidence_certainty_as_reported": "LoE 2", "scope": "Chemotherapy outside the separately assessed HSCT / radiotherapy settings", "summary_en": "Insufficient evidence to recommend for or against PBM for prevention during chemotherapy.", "summary_fi": "Näyttö ei riitä suositukseen PBM:n puolesta tai sitä vastaan solunsalpaajahoidon mukosiitin ehkäisyssä.", "locator": "7.6; PDF p. 197", "evidence_anchor": "Für die Anwendung von photobiomodulierender Therapie zur Prophylaxe", "caveat_en": "German grade 0 is an open / may-use recommendation, not zero evidence. Prevention and treatment settings are distinct.", "caveat_fi": "Saksalainen suositusluokka 0 tarkoittaa avointa, käyttöä harkitsevaa suositusta; se ei tarkoita näytön puuttumista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "S3-SUPPORT-HSCT-PREV", "document_id": "german_supportive", "specialty": "Oncology / supportive care", "condition_en": "Oral mucositis prevention in HSCT", "condition_fi": "Suun mukosiitin ehkäisy kantasolusiirrossa", "direction": "may_consider", "strength_as_reported": "Grade 0 (open recommendation); strong consensus", "evidence_certainty_as_reported": "LoE 1", "scope": "HSCT, using one of the proposed complete protocols", "summary_en": "PBM may be performed to prevent oral mucositis in HSCT with a specified protocol.", "summary_fi": "PBM:ää voidaan käyttää mukosiitin ehkäisyyn kantasolusiirrossa yhdellä määritellyistä protokollista.", "locator": "7.11; PDF p. 211", "evidence_anchor": "Die Photobiomodulierende Therapie kann zur Prophylaxe", "caveat_en": "German grade 0 is an open / may-use recommendation, not zero evidence. Prevention and treatment settings are distinct.", "caveat_fi": "Saksalainen suositusluokka 0 tarkoittaa avointa, käyttöä harkitsevaa suositusta; se ei tarkoita näytön puuttumista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "S3-SUPPORT-CHEMO-TREAT", "document_id": "german_supportive", "specialty": "Oncology / supportive care", "condition_en": "Treatment of oral mucositis during chemotherapy", "condition_fi": "Solunsalpaajahoidon mukosiitin hoito", "direction": "insufficient_evidence", "strength_as_reported": "Evidence-based statement; strong consensus", "evidence_certainty_as_reported": "LoE 4", "scope": "Treatment of established chemotherapy-related oral mucositis", "summary_en": "Insufficient evidence to recommend for or against PBM treatment.", "summary_fi": "Näyttö ei riitä suositukseen jo kehittyneen solunsalpaajamukosiitin PBM-hoidosta.", "locator": "7.17; PDF p. 221", "evidence_anchor": "zur Therapie von oraler Mukositis bei Chemotherapie", "caveat_en": "German grade 0 is an open / may-use recommendation, not zero evidence. Prevention and treatment settings are distinct.", "caveat_fi": "Saksalainen suositusluokka 0 tarkoittaa avointa, käyttöä harkitsevaa suositusta; se ei tarkoita näytön puuttumista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "S3-SUPPORT-HSCT-TREAT", "document_id": "german_supportive", "specialty": "Oncology / supportive care", "condition_en": "Treatment of oral mucositis in HSCT", "condition_fi": "Kantasolusiirtoon liittyvän mukosiitin hoito", "direction": "insufficient_evidence", "strength_as_reported": "Evidence-based statement; strong consensus", "evidence_certainty_as_reported": "LoE 3", "scope": "HSCT with or without total body irradiation; established oral mucositis", "summary_en": "Insufficient evidence to recommend for or against PBM treatment in HSCT.", "summary_fi": "Näyttö ei riitä suositukseen PBM-hoidosta kantasolusiirron yhteydessä jo kehittyneeseen mukosiittiin.", "locator": "7.22; PDF p. 227", "evidence_anchor": "zur Therapie von oraler Mukositis bei Patient*innen mit HSZT", "caveat_en": "German grade 0 is an open / may-use recommendation, not zero evidence. Prevention and treatment settings are distinct.", "caveat_fi": "Saksalainen suositusluokka 0 tarkoittaa avointa, käyttöä harkitsevaa suositusta; se ei tarkoita näytön puuttumista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "S3-SUPPORT-RD-PREV", "document_id": "german_supportive", "specialty": "Oncology / supportive care", "condition_en": "Radiation dermatitis prevention", "condition_fi": "Sädeihottuman ehkäisy", "direction": "may_consider", "strength_as_reported": "Grade 0 (open recommendation); strong consensus", "evidence_certainty_as_reported": "LoE 2", "scope": "Radiotherapy-associated dermatitis prevention; supporting studies mainly breast irradiation", "summary_en": "PBM may be used for radiation dermatitis prevention.", "summary_fi": "PBM:ää voidaan käyttää sädeihottuman ehkäisyyn.", "locator": "11.59; PDF p. 480", "evidence_anchor": "kann zur Prophylaxe der Radiodermatitis angewendet werden", "caveat_en": "German grade 0 is an open / may-use recommendation, not zero evidence. Prevention and treatment settings are distinct.", "caveat_fi": "Saksalainen suositusluokka 0 tarkoittaa avointa, käyttöä harkitsevaa suositusta; se ei tarkoita näytön puuttumista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "S3-SUPPORT-RAD-ULCER", "document_id": "german_supportive", "specialty": "Oncology / supportive care", "condition_en": "Radiation-induced skin ulcers", "condition_fi": "Sädehoidon aiheuttamat ihohaavat", "direction": "may_consider", "strength_as_reported": "Grade 0 (open recommendation); strong consensus", "evidence_certainty_as_reported": "LoE 3", "scope": "Radiation-induced skin ulcers; selected individual cases", "summary_en": "PBM may be considered for radiation-induced skin ulcers in individual cases.", "summary_fi": "PBM-hoitoa voidaan harkita yksittäistapauksissa sädehoidon aiheuttamiin ihohaavoihin.", "locator": "11.73; PDF p. 491", "evidence_anchor": "Zur Therapie radiogener Hautulzera", "caveat_en": "German grade 0 is an open / may-use recommendation, not zero evidence. Prevention and treatment settings are distinct.", "caveat_fi": "Saksalainen suositusluokka 0 tarkoittaa avointa, käyttöä harkitsevaa suositusta; se ei tarkoita näytön puuttumista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "S3-SUPPORT-RT-OM-PREV", "document_id": "german_supportive", "specialty": "Oncology / supportive care", "condition_en": "Radiation-induced oral mucositis prevention", "condition_fi": "Sädehoidon aiheuttaman suun mukosiitin ehkäisy", "direction": "may_consider", "strength_as_reported": "Grade 0 (open recommendation); strong consensus", "evidence_certainty_as_reported": "LoE 1", "scope": "Intraoral PBM during radiotherapy or chemoradiotherapy; specified protocols", "summary_en": "Intraoral PBM may be used to prevent radiation-induced oral mucositis with a listed regimen.", "summary_fi": "Suunsisäistä PBM:ää voidaan käyttää mukosiitin ehkäisyyn säde- tai kemosädehoidossa määritellyillä protokollilla.", "locator": "11.93; PDF p. 509", "evidence_anchor": "Eine Prophylaxe der radiogenen oralen Mukositis", "caveat_en": "German grade 0 is an open / may-use recommendation, not zero evidence. Prevention and treatment settings are distinct.", "caveat_fi": "Saksalainen suositusluokka 0 tarkoittaa avointa, käyttöä harkitsevaa suositusta; se ei tarkoita näytön puuttumista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "WOUND-S3-GERMAN", "document_id": "german_wounds", "specialty": "Wound care", "condition_en": "Hard-to-heal chronic wounds: phototherapy / LLLT evidence", "condition_fi": "Vaikeasti paranevat krooniset haavat: valo- ja laserhoito", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation adopted; 100% consensus", "evidence_certainty_as_reported": "Low for mixed phototherapy complete healing; very low for LLLT area reduction", "scope": "Chronic wounds due to PAD, diabetes or venous insufficiency; identified LLLT evidence from diabetic foot ulcers", "summary_en": "No phototherapy recommendation was adopted because evidence was uncertain; LLLT-specific area-reduction evidence is rated very low.", "summary_fi": "Valohoidosta ei anneta suositusta epävarman näytön vuoksi. LLLT:n haavapinta-alaa koskeva näyttö arvioidaan hyvin matalaksi.", "locator": "Section 9.3.2 Phototherapie; printed p. 179", "evidence_anchor": "Wegen unsicherer Evidenzgrundlage wurde keine Empfehlung verabschiedet", "caveat_en": "Grouped phototherapy includes several light types; favorable pooled results did not become a positive recommendation.", "caveat_fi": "Valohoitoryhmä sisältää eri valotyyppejä. Myönteiset meta-analyysitulokset eivät johtaneet myönteiseen suositukseen.", "intervention": "Mixed phototherapy; LLLT separately discussed", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-AUSTRIA", "document_id": "austria_back", "specialty": "Musculoskeletal / primary care", "condition_en": "Chronic nonspecific low back pain: trigger-point emphasis", "condition_fi": "Krooninen epäspesifi alaselkäkipu: etenkin triggerpisteet", "direction": "may_consider", "strength_as_reported": "Single upward arrow (positive recommendation)", "evidence_certainty_as_reported": "", "scope": "Chronic nonspecific low back pain; especially treatment of trigger points", "summary_en": "The short-version table gives laser a positive recommendation in the chronic column, especially for trigger points.", "summary_fi": "Tiivistelmän taulukossa laser saa myönteisen suosituksen kroonisessa alaselkäkivussa, etenkin triggerpisteiden hoitoon.", "locator": "PDF p. 12, chronic column, footnote 15; table visually verified", "evidence_anchor": "Lasertherapie", "caveat_en": "The short version does not specify low-level versus high-intensity laser. Not generalized to acute or subacute pain.", "caveat_fi": "Tiivistelmä ei erittele matala- ja suuritehoista laseria. Kanta koskee kroonista kipua.", "intervention": "Laser therapy; device class unspecified", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_guideline_short_version", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-SIGN", "document_id": "sign_chronicpain", "specialty": "Musculoskeletal / chronic pain", "condition_en": "Chronic low back pain", "condition_fi": "Krooninen alaselkäkipu", "direction": "may_consider", "strength_as_reported": "B", "evidence_certainty_as_reported": "", "scope": "Chronic low back pain", "summary_en": "LLLT should be considered as a treatment option for chronic low back pain.", "summary_fi": "LLLT:tä tulisi harkita kroonisen alaselkäkivun hoitovaihtoehtona.", "locator": "Section 7, PDF p. 34 / printed p. 28", "evidence_anchor": "Low level laser therapy should be considered", "caveat_en": "The retrieved text is the December 2013 edition; a 2019 date from a review was not adopted.", "caveat_fi": "Luettu teksti on joulukuulta 2013; sitä ei merkitty vuoden 2019 suositukseksi.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": true, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "SHOULDER-DUTCH", "document_id": "dutch_shoulder", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Subacromial pain syndrome", "condition_fi": "Subakromiaalinen kipuoireyhtymä", "direction": "descriptive_support", "strength_as_reported": "Level 3 evidence conclusion", "evidence_certainty_as_reported": "", "scope": "Laser types combined; pain after 2–4 weeks versus placebo or ultrasound", "summary_en": "The evidence section says laser of all types appears more effective for short-term pain than placebo or ultrasound.", "summary_fi": "Näyttöosio kuvaa eri lasertyyppejä myönteisesti lyhytaikaisen kivun kannalta lumeeseen tai ultraääneen verrattuna.", "locator": "Other interventions, Level 3 evidence conclusion", "evidence_anchor": "Laser treatment (of all types) appears to be more effective", "caveat_en": "This is an evidence conclusion, not a separate strong laser prescription; includes high-intensity laser studies.", "caveat_fi": "Kuvaileva näytönarvio, ei erillinen vahva laserhoitosuositus; mukana myös suuritehoista laseria.", "intervention": "Low- and high-intensity laser types combined", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ANKLE-DUTCH", "document_id": "dutch_ankle", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Acute lateral ankle sprain", "condition_fi": "Akuutti nilkan ulkosivun nivelsidevamma", "direction": "against", "strength_as_reported": "Other therapies not advised; recommendation level 2", "evidence_certainty_as_reported": "Laser evidence described as level 1", "scope": "Acute lateral ankle sprain; laser among other adjunctive modalities", "summary_en": "Laser is among modalities not advised because no strong evidence of effectiveness was identified.", "summary_fi": "Laser kuuluu hoitoihin, joita ei suositella akuuttiin nilkan ulkosivun nivelsidevammaan puuttuvan vahvan hyötynäytön vuoksi.", "locator": "Other therapies; evidence statement and unchanged recommendation", "evidence_anchor": "they are not advised in the treatment of acute LAS", "caveat_en": "The reported evidence and recommendation levels use the Dutch source's framework.", "caveat_fi": "Näytön ja suosituksen numeroluokat ovat lähteen oman järjestelmän mukaisia.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-CHIRO-MULTIMODAL", "document_id": "chiro_neck", "specialty": "Musculoskeletal rehabilitation", "condition_en": "Chronic mechanical neck pain: multimodal care", "condition_fi": "Krooninen mekaaninen niskakipu: monimuotoinen hoito", "direction": "recommended", "strength_as_reported": "Strong for multimodal manipulative care", "evidence_certainty_as_reported": "", "scope": "Chronic adult mechanical neck pain; LLLT among components of multimodal manipulation-based care", "summary_en": "Lists LLLT as one component of a strongly recommended multimodal approach.", "summary_fi": "LLLT mainitaan yhtenä vahvan suosituksen saavan, manipulaatiota sisältävän monimuotoisen hoidon osana.", "locator": "Recommendations: manipulation / multimodal chronic neck pain", "evidence_anchor": "low-level laser therapy, soft", "caveat_en": "The strong recommendation applies to multimodal care and cannot be transferred to LLLT alone.", "caveat_fi": "Vahva luokitus koskee yhdistelmähoitoa, ei LLLT:tä yksinään.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text_author_article_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "AGA-JAPAN", "document_id": "japan_aga", "specialty": "Dermatology", "condition_en": "Male and female pattern hair loss", "condition_fi": "Miesten ja naisten androgeeninen hiustenlähtö", "direction": "recommended", "strength_as_reported": "B", "evidence_certainty_as_reported": "", "scope": "Male and female pattern hair loss; CQ5", "summary_en": "Irradiation by LED and low-level lasers is recommended.", "summary_fi": "LED- ja matalatehoista laserhoitoa suositellaan miesten ja naisten androgeeniseen hiustenlähtöön.", "locator": "CQ5; PDF pp. 8–9", "evidence_anchor": "Irradiation by light-emitting diodes (LED) and low-level lasers is recommended.", "caveat_en": "2017 guideline edition, English publication 2018. B is the source's recommendation grade; not a harmonized GRADE rating.", "caveat_fi": "Suositusversio 2017, englanninkielinen julkaisu 2018. B on lähteen oma suositusluokka.", "intervention": "LED and low-level lasers", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "AGA-SPAIN-ADJUNCT", "document_id": "spain_aga", "specialty": "Dermatology", "condition_en": "Androgenetic alopecia: adjunctive treatment", "condition_fi": "Androgeeninen hiustenlähtö: liitännäishoito", "direction": "may_consider", "strength_as_reported": "", "evidence_certainty_as_reported": "", "scope": "Individualized adjunctive treatment", "summary_en": "The consensus describes LLLT as having proven but variable adjunctive efficacy and advises individualized use.", "summary_fi": "Konsensus pitää LLLT:n liitännäistehoa osoitettuna mutta vaihtelevana ja suosittaa yksilöllistä harkintaa.", "locator": "Procedures in the management of androgenetic alopecia", "evidence_anchor": "low-level laser therapy were considered to have proven but variable efficacy", "caveat_en": "Expert consensus; a laser-specific formal grade was not verified in this narrative passage.", "caveat_fi": "Asiantuntijakonsensus; tämän tekstikohdan laserkohtaista suositusluokkaa ei vahvistettu.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "AGA-SPAIN-ADOLESCENT", "document_id": "spain_aga", "specialty": "Dermatology", "condition_en": "Androgenetic alopecia in adolescents", "condition_fi": "Nuorten androgeeninen hiustenlähtö", "direction": "may_consider", "strength_as_reported": "D", "evidence_certainty_as_reported": "Level 5", "scope": "Adolescents with male/female androgenetic alopecia; adjunctive treatment", "summary_en": "LLLT may be considered as an adjunct, while the panel explicitly states that efficacy and safety evidence in adolescents is insufficient.", "summary_fi": "LLLT:tä voidaan harkita lisähoitona, mutta paneeli toteaa nuorten teho- ja turvallisuusnäytön riittämättömäksi.", "locator": "Table 7; Pediatric/Adolescent patients", "evidence_anchor": "Adjuvant treatments such as platelet-rich plasma therapy or low-level laser therapy can be considered in adolescent patients", "caveat_en": "Expert-opinion level 5 / grade D is not a finding of established efficacy or safety in adolescents.", "caveat_fi": "Asiantuntijataso 5 / luokka D ei osoita vakiintunutta tehoa tai turvallisuutta nuorilla.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "AGA-SPAIN-PREGNANCY", "document_id": "spain_aga", "specialty": "Dermatology", "condition_en": "Androgenetic alopecia during pregnancy", "condition_fi": "Androgeeninen hiustenlähtö raskauden aikana", "direction": "may_consider", "strength_as_reported": "D", "evidence_certainty_as_reported": "Level 5", "scope": "Pregnancy; only if clinically necessary", "summary_en": "The expert consensus allows consideration of LLLT if clinically necessary during pregnancy.", "summary_fi": "Asiantuntijakonsensus sallii LLLT:n harkinnan raskauden aikana, jos hoito on kliinisesti tarpeellinen.", "locator": "Table 7; Pregnancy", "evidence_anchor": "Low-level laser therapy and PRP therapy may be considered if clinically necessary", "caveat_en": "Expert opinion, not a general conclusion that PBM is proven safe during pregnancy or for other body sites.", "caveat_fi": "Asiantuntijakanta ei osoita PBM:n yleistä turvallisuutta raskaudessa tai muille kehon alueille.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus" }, { "id": "FIBRO-CHINA", "document_id": "china_fibromyalgia", "specialty": "Pain", "condition_en": "Fibromyalgia", "condition_fi": "Fibromyalgia", "direction": "may_consider", "strength_as_reported": "Conditional", "evidence_certainty_as_reported": "Low certainty", "scope": "Fibromyalgia; compared with no intervention", "summary_en": "The guideline conditionally suggests LLLT over no intervention.", "summary_fi": "Suositus ehdottaa LLLT:tä ehdollisesti verrattuna siihen, ettei interventiota anneta.", "locator": "Table 1 and §3.2.4.3", "evidence_anchor": "We suggest low‐level laser therapy to patients with fibromyalgia over no interventions", "caveat_en": "Retains the panel's stated comparator. The supporting evidence discussion also includes placebo-controlled trials; other guidelines reach different conclusions.", "caveat_fi": "Vertailu on säilytetty paneelin sanamuodon mukaisena. Perusteluissa on myös lumevertailuja; muiden suositusten kannat poikkeavat tästä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-ACOEM", "document_id": "acoem_back", "specialty": "Musculoskeletal", "condition_en": "Low back pain", "condition_fi": "Alaselkäkipu", "direction": "against", "strength_as_reported": "Not Recommended, Evidence (C)", "evidence_certainty_as_reported": "Level of confidence: Moderate", "scope": "Low back pain", "summary_en": "LLLT is not recommended for treatment of low back pain.", "summary_fi": "LLLT:tä ei suositella alaselkäkivun hoitoon.", "locator": "Low-level Laser Therapy for Treatment of Low Back Pain", "evidence_anchor": "Low-level laser therapy is not recommended for treatment of low back pain.", "caveat_en": "Guideline effective 13 February 2020; the URL's 2021 directory is not the edition year.", "caveat_fi": "Suositus tuli voimaan 13.2.2020; URL:n 2021-hakemisto ei ole suositusvuosi.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-ACOEM", "document_id": "acoem_cervical", "specialty": "Musculoskeletal", "condition_en": "Cervicothoracic pain", "condition_fi": "Kaula- ja rintarangan alueen kipu", "direction": "insufficient_evidence", "strength_as_reported": "No Recommendation, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Acute, subacute or chronic cervicothoracic pain", "summary_en": "No recommendation for or against LLLT.", "summary_fi": "LLLT:n puolesta tai vastaan ei anneta suositusta.", "locator": "Low-Level Laser Therapy; PDF p. 84", "evidence_anchor": "There is no recommendation for or against the use of low-level laser therapy", "caveat_en": "Effective 17 October 2018; the retrieved copy has a 2020 copyright.", "caveat_fi": "Voimaan 17.10.2018; haetun PDF:n tekijänoikeusvuosi on 2020.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RC-ACOEM", "document_id": "acoem_shoulder", "specialty": "Musculoskeletal", "condition_en": "Rotator cuff tendinopathy", "condition_fi": "Kiertäjäkalvosimen tendinopatia", "direction": "against", "strength_as_reported": "Moderately Not Recommended, Evidence (B)", "evidence_certainty_as_reported": "Level of confidence: Moderate", "scope": "Rotator cuff tendinopathies", "summary_en": "LLLT is not recommended for rotator cuff tendinopathy.", "summary_fi": "LLLT:tä ei suositella kiertäjäkalvosimen tendinopatiaan.", "locator": "PDF p. 114", "evidence_anchor": "Low-level laser therapy is not recommended for treatment of rotator cuff tendinopathies.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "BICEPS-ACOEM", "document_id": "acoem_shoulder", "specialty": "Musculoskeletal", "condition_en": "Bicipital tendinopathy", "condition_fi": "Hauislihaksen jännevaiva", "direction": "against", "strength_as_reported": "Not Recommended, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Bicipital tendinopathies", "summary_en": "LLLT is not recommended.", "summary_fi": "LLLT:tä ei suositella.", "locator": "PDF p. 216", "evidence_anchor": "Low-level laser therapy is not recommended for the treatment of bicipital tendinopathies.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "MYOFASCIAL-ACOEM", "document_id": "acoem_shoulder", "specialty": "Musculoskeletal", "condition_en": "Trigger points and myofascial pain", "condition_fi": "Triggerpisteet ja myofaskiaalinen kipu", "direction": "insufficient_evidence", "strength_as_reported": "No Recommendation, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Trigger points / myofascial pain", "summary_en": "No recommendation for or against LLLT because the evidence is conflicting.", "summary_fi": "LLLT:n puolesta tai vastaan ei anneta suositusta ristiriitaisen näytön vuoksi.", "locator": "PDF p. 662", "evidence_anchor": "There is no recommendation for or against the use of low-level laser therapy for the treatment of trigger points/myofascial pain.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ELBOW-ACOEM", "document_id": "acoem_elbow", "specialty": "Musculoskeletal", "condition_en": "Lateral or medial epicondylalgia", "condition_fi": "Lateraalinen tai mediaalinen epikondylalgia", "direction": "against", "strength_as_reported": "Moderately Not Recommended, Evidence (B)", "evidence_certainty_as_reported": "", "scope": "Acute, subacute or chronic lateral/medial epicondylalgia", "summary_en": "LLLT is moderately not recommended.", "summary_fi": "LLLT:tä ei suositella; lähteen kielteinen suositus on kohtalainen.", "locator": "PDF p. 114", "evidence_anchor": "Low-level laser therapy is moderately not recommended for the treatment of acute, subacute, or chronic lateral or medial epicondylalgia.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "PRONATOR-ACOEM", "document_id": "acoem_elbow", "specialty": "Musculoskeletal", "condition_en": "Pronator syndrome", "condition_fi": "Pronator-oireyhtymä", "direction": "against", "strength_as_reported": "Not Recommended, Insufficient Evidence (I)", "evidence_certainty_as_reported": "", "scope": "Acute, subacute or chronic pronator syndrome", "summary_en": "LLLT is not recommended; the source identifies insufficient evidence.", "summary_fi": "LLLT:tä ei suositella; lähde luokittelee näytön riittämättömäksi.", "locator": "PDF p. 144", "evidence_anchor": "Low-level laser therapy is not recommended for acute, subacute, or chronic pronator syndrome.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RADIAL-ACOEM", "document_id": "acoem_elbow", "specialty": "Musculoskeletal", "condition_en": "Radial nerve entrapment / radial tunnel syndrome", "condition_fi": "Värttinähermon pinne / radiaalitunnelioireyhtymä", "direction": "against", "strength_as_reported": "Not Recommended, Insufficient Evidence (I)", "evidence_certainty_as_reported": "", "scope": "Acute, subacute or chronic radial nerve entrapment", "summary_en": "LLLT is not recommended.", "summary_fi": "LLLT:tä ei suositella.", "locator": "PDF p. 155", "evidence_anchor": "Low-level laser therapy is not recommended for acute, subacute, or chronic radial nerve entrapment", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ULNAR-ACOEM", "document_id": "acoem_elbow", "specialty": "Musculoskeletal", "condition_en": "Ulnar neuropathy", "condition_fi": "Kyynärhermon neuropatia", "direction": "against", "strength_as_reported": "Not Recommended, Insufficient Evidence (I)", "evidence_certainty_as_reported": "", "scope": "Acute, subacute or chronic ulnar neuropathy", "summary_en": "LLLT is not recommended.", "summary_fi": "LLLT:tä ei suositella.", "locator": "PDF pp. 173–174", "evidence_anchor": "Low-level laser therapy is not recommended for the treatment of acute, subacute, or chronic ulnar neuropathies.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "CTS-ACOEM", "document_id": "acoem_hand", "specialty": "Musculoskeletal", "condition_en": "Carpal tunnel syndrome", "condition_fi": "Rannekanavaoireyhtymä", "direction": "against", "strength_as_reported": "Not Recommended, Evidence (C)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Acute, subacute or chronic CTS", "summary_en": "LLLT is not recommended for CTS.", "summary_fi": "LLLT:tä ei suositella rannekanavaoireyhtymään.", "locator": "PDF p. 99", "evidence_anchor": "Low level laser therapy is not recommended for treatment of acute, subacute, or chronic CTS.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "HAND-OA-ACOEM", "document_id": "acoem_hand", "specialty": "Musculoskeletal", "condition_en": "Hand osteoarthritis", "condition_fi": "Käsien nivelrikko", "direction": "against", "strength_as_reported": "Moderately Not Recommended, Evidence (B)", "evidence_certainty_as_reported": "Level of confidence: Moderate", "scope": "Hand osteoarthritis", "summary_en": "LLLT is moderately not recommended.", "summary_fi": "LLLT:tä ei suositella; lähteen kielteinen suositus on kohtalainen.", "locator": "PDF p. 324", "evidence_anchor": "Low-level laser therapy is moderately not recommended for treatment of hand osteoarthrosis.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "KNEE-PAIN-ACOEM", "document_id": "acoem_knee", "specialty": "Musculoskeletal", "condition_en": "Knee pain", "condition_fi": "Polvikipu", "direction": "against", "strength_as_reported": "Not Recommended, Evidence (C)", "evidence_certainty_as_reported": "", "scope": "Acute, subacute or chronic knee pain", "summary_en": "LLLT is not recommended for knee pain.", "summary_fi": "LLLT:tä ei suositella polvikivun hoitoon.", "locator": "Summary table PDF p. 9; body p. 91", "evidence_anchor": "The use of low-level laser therapy is not recommended for treatment of osteoarthrosis and acute, subacute, or chronic knee pain.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "KNEE-OA-ACOEM", "document_id": "acoem_knee", "specialty": "Musculoskeletal", "condition_en": "Knee osteoarthritis", "condition_fi": "Polven nivelrikko", "direction": "against", "strength_as_reported": "Not Recommended, Evidence (C)", "evidence_certainty_as_reported": "", "scope": "Knee osteoarthritis", "summary_en": "LLLT is not recommended for knee osteoarthritis.", "summary_fi": "LLLT:tä ei suositella polven nivelrikkoon.", "locator": "Summary table PDF p. 9; body p. 91", "evidence_anchor": "The use of low-level laser therapy is not recommended for treatment of osteoarthrosis and acute, subacute, or chronic knee pain.", "caveat_en": "Shares one body recommendation with general knee pain; these rows are not independent recommendations.", "caveat_fi": "Sama tekstisuositus kuin yleisessä polvikivussa; rivit eivät ole riippumattomia suosituksia.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "MENISCUS-ACOEM", "document_id": "acoem_knee", "specialty": "Musculoskeletal", "condition_en": "Meniscal tears", "condition_fi": "Nivelkierukan repeämät", "direction": "against", "strength_as_reported": "Not Recommended, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Meniscal tears", "summary_en": "LLLT is not recommended for meniscal tears.", "summary_fi": "LLLT:tä ei suositella nivelkierukan repeämiin.", "locator": "Summary table PDF p. 9; LLLT recommendation p. 146", "evidence_anchor": "Low-level Laser Therapy for Meniscal tears", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "KNEE-LIGAMENT-ACOEM", "document_id": "acoem_knee", "specialty": "Musculoskeletal", "condition_en": "Knee sprains and cruciate ligament tears", "condition_fi": "Polven nyrjähdykset ja ristisidevammat", "direction": "insufficient_evidence", "strength_as_reported": "No Recommendation, Insufficient Evidence (I); grouped", "evidence_certainty_as_reported": "", "scope": "Knee sprains; ACL / PCL tears; menu of interventions including LLLT", "summary_en": "No recommendation for or against a group of modalities including LLLT because of insufficient evidence.", "summary_fi": "LLLT:n sisältävän hoitoryhmän puolesta tai vastaan ei anneta suositusta riittämättömän näytön vuoksi.", "locator": "PDF pp. 133, 139–140", "evidence_anchor": "iontophoresis, low-level laser therapy, phonophoresis", "caveat_en": "Group-level recommendation; laser-specific efficacy is not established.", "caveat_fi": "Usean hoidon yhteisluokitus ei osoita laserin erillistä tehoa.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACHILLES-ACOEM-CHRONIC", "document_id": "acoem_ankle", "specialty": "Musculoskeletal", "condition_en": "Selected chronic Achilles tendinopathy", "condition_fi": "Valikoidut krooniset akillesjännevaivat", "direction": "recommended", "strength_as_reported": "Recommended, Evidence (C)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Selected chronic cases, generally after failed NSAIDs, eccentric exercise, iontophoresis and injection(s); concurrent eccentric exercise", "summary_en": "LLLT is recommended for selected chronic Achilles tendinopathy after prior treatments have generally failed, with concurrent eccentric exercise.", "summary_fi": "LLLT:tä suositellaan valikoiduissa kroonisissa akillesjännevaivoissa aiempien hoitojen yleensä epäonnistuttua, yhdessä eksentrisen harjoittelun kanssa.", "locator": "PDF p. 68", "evidence_anchor": "Low-level laser therapy is recommended for treatment of select patients with chronic Achilles tendinopathy.", "caveat_en": "Restricted later-line setting; not routine first-line treatment. Source regimen: 12 sessions over 8 weeks. Distinct from APTA 2024's recommendation against routine LLLT.", "caveat_fi": "Rajattu myöhempi hoitovaihe, ei yleinen ensilinjan suositus. Lähteen jakso on 12 käyntiä 8 viikossa. Eri käyttötilanne kuin APTA:n vuoden 2024 kielteisessä suosituksessa.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACHILLES-ACOEM-OTHER", "document_id": "acoem_ankle", "specialty": "Musculoskeletal", "condition_en": "Acute, subacute or postoperative Achilles tendinopathy", "condition_fi": "Akuutti, subakuutti tai leikkauksen jälkeinen akillesjännevaiva", "direction": "insufficient_evidence", "strength_as_reported": "No Recommendation, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Acute, subacute or postoperative Achilles tendinopathy", "summary_en": "No recommendation for or against LLLT in these settings.", "summary_fi": "Näissä tilanteissa LLLT:n puolesta tai vastaan ei anneta suositusta.", "locator": "PDF p. 69", "evidence_anchor": "There is no recommendation for or against the use of low-level laser therapy for treatment of acute, subacute, or post-operative Achilles tendinopathy.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ANKLE-ACOEM-ACUTE", "document_id": "acoem_ankle", "specialty": "Musculoskeletal", "condition_en": "Acute ankle sprain", "condition_fi": "Akuutti nilkan nyrjähdys", "direction": "against", "strength_as_reported": "Moderately Not Recommended, Evidence (B)", "evidence_certainty_as_reported": "Level of confidence: Moderate", "scope": "Acute ankle sprain", "summary_en": "LLLT is not recommended for acute ankle sprain.", "summary_fi": "LLLT:tä ei suositella akuuttiin nilkan nyrjähdykseen.", "locator": "PDF p. 179", "evidence_anchor": "Low-level laser therapy is not recommended for treatment of acute ankle sprain.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ANKLE-ACOEM-CHRONIC", "document_id": "acoem_ankle", "specialty": "Musculoskeletal", "condition_en": "Subacute or chronic ankle sprain", "condition_fi": "Subakuutti tai krooninen nilkan nyrjähdys", "direction": "against", "strength_as_reported": "Not Recommended, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Moderate", "scope": "Subacute or chronic ankle sprain", "summary_en": "LLLT is not recommended.", "summary_fi": "LLLT:tä ei suositella.", "locator": "PDF p. 179", "evidence_anchor": "Low-level laser therapy is not recommended for treatment of subacute or chronic ankle sprain.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "HEEL-ACOEM", "document_id": "acoem_ankle", "specialty": "Musculoskeletal", "condition_en": "Plantar fasciitis", "condition_fi": "Plantaarifaskiitti", "direction": "insufficient_evidence", "strength_as_reported": "No Recommendation, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Acute, subacute or chronic plantar fasciitis, as stated in the LLLT heading", "summary_en": "The summary table and LLLT section classify this as no recommendation; the rationale describes conflicting LLLT studies.", "summary_fi": "Yhteenvetotaulukko ja LLLT-osio luokittelevat kannan ilman suositusta; perusteluissa LLLT-tutkimusten tulokset ovat ristiriitaisia.", "locator": "Summary table; PDF p. 304, LLLT heading and rationale", "evidence_anchor": "There are two moderate-quality studies providing conflicting results for the use of LLLT.", "caveat_en": "Source wording inconsistency: the section's opening sentence says low-dose radiation (radiotherapy), despite the LLLT heading and rationale. Retained with this explicit flag.", "caveat_fi": "Lähteen sanamuotoristiriita: aloituslause puhuu pieniannoksisesta sädehoidosta, vaikka otsikko ja perustelut koskevat LLLT:tä. Maininta on mukana tällä varauksella.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "HIP-ACOEM", "document_id": "acoem_hip", "specialty": "Musculoskeletal", "condition_en": "Hip osteoarthritis and other hip pain", "condition_fi": "Lonkan nivelrikko ja muu lonkkakipu", "direction": "insufficient_evidence", "strength_as_reported": "No Recommendation, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Hip osteoarthritis or acute, subacute or chronic hip pain", "summary_en": "No recommendation for or against LLLT.", "summary_fi": "LLLT:n puolesta tai vastaan ei anneta suositusta.", "locator": "PDF p. 144", "evidence_anchor": "There is no recommendation for or against the use of low-level laser therapy for treatment of osteoarthrosis or acute, subacute, or chronic hip pain.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "CRPS-ACOEM", "document_id": "acoem_chronicpain", "specialty": "Pain", "condition_en": "Complex regional pain syndrome", "condition_fi": "Monimuotoinen paikallinen kipuoireyhtymä (CRPS)", "direction": "insufficient_evidence", "strength_as_reported": "No Recommendation, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "CRPS; the source discusses prior trials of established treatments", "summary_en": "No recommendation regarding LLLT for CRPS.", "summary_fi": "LLLT:stä ei anneta suositusta CRPS:n hoitoon.", "locator": "PDF p. 151", "evidence_anchor": "There is no recommendation regarding low-level laser therapy (LLLT) for treatment of complex regional pain syndrome", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "FIBRO-ACOEM", "document_id": "acoem_chronicpain", "specialty": "Pain", "condition_en": "Fibromyalgia", "condition_fi": "Fibromyalgia", "direction": "against", "strength_as_reported": "Moderately Not Recommended, Evidence (B)", "evidence_certainty_as_reported": "Level of confidence: Moderate", "scope": "Fibromyalgia", "summary_en": "LLLT is not recommended for fibromyalgia.", "summary_fi": "LLLT:tä ei suositella fibromyalgiaan.", "locator": "PDF pp. 290–291", "evidence_anchor": "Low-level laser therapy is not recommended for fibromyalgia.", "caveat_en": "Effective 22 December 2025; the URL's 2026 directory is not the edition year. Contrasts with the conditional positive 2025 Chinese guideline.", "caveat_fi": "Voimaan 22.12.2025; URL:n 2026-hakemisto ei ole suositusvuosi. Kanta poikkeaa kiinalaisen 2025-suosituksen ehdollisesta myönteisestä kannasta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NEUROPATHIC-ACOEM", "document_id": "acoem_chronicpain", "specialty": "Pain", "condition_en": "Neuropathic pain", "condition_fi": "Neuropaattinen kipu", "direction": "against", "strength_as_reported": "Not Recommended, Insufficient Evidence (I)", "evidence_certainty_as_reported": "Level of confidence: Low", "scope": "Neuropathic pain", "summary_en": "LLLT is not recommended for neuropathic pain.", "summary_fi": "LLLT:tä ei suositella neuropaattiseen kipuun.", "locator": "PDF p. 379", "evidence_anchor": "Low-level laser therapy is not recommended for treatment of neuropathic pain.", "caveat_en": "", "caveat_fi": "", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RA-OTTAWA", "document_id": "ottawa_ra", "specialty": "Rheumatology", "condition_en": "Rheumatoid arthritis", "condition_fi": "Nivelreuma", "direction": "recommended", "strength_as_reported": "Not verified from abstract", "evidence_certainty_as_reported": "", "scope": "Adult rheumatoid arthritis", "summary_en": "The Ottawa Panel abstract explicitly recommends LLLT among physical therapies for rheumatoid arthritis.", "summary_fi": "Ottawan paneelin abstrakti suosittelee nimenomaisesti LLLT:tä muiden fysikaalisten hoitojen joukossa nivelreumaan.", "locator": "Abstract; conclusion", "evidence_anchor": "Ottawa Panel recommends the use of low-level laser therapy", "caveat_en": "Historical 2004 guideline; abstract-only verification. No laser-specific grade or detailed population restriction inferred.", "caveat_fi": "Historiallinen 2004-suositus; tarkistus vain abstraktista. Laserkohtaista luokkaa tai tarkempaa potilasrajausta ei päätellä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": true, "checked_on": "2026-10-15", "verification_depth": "abstract", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "RA-SPAIN", "document_id": "spain_ra", "specialty": "Rheumatology", "condition_en": "Rheumatoid arthritis: short-term pain", "condition_fi": "Nivelreuma: lyhytaikainen kipu", "direction": "descriptive_support", "strength_as_reported": "", "evidence_certainty_as_reported": "", "scope": "Symptomatic short-term treatment; comparison with placebo", "summary_en": "The guideline narrative states that low-power laser appears to reduce pain versus placebo and cites short-term symptomatic efficacy.", "summary_fi": "Suositusteksti arvioi matalatehoisen laserin näyttävän vähentävän kipua lumeeseen verrattuna ja viittaa lyhytaikaiseen oirehyötyyn.", "locator": "Printed p. 109; physical therapies", "evidence_anchor": "El láser de baja potencia parece conseguir una disminución", "caveat_en": "No separate laser-specific prescription grade was verified. The document's printed edition is 2019.", "caveat_fi": "Erillistä laserkohtaista suositusluokkaa ei vahvistettu. Asiakirjan painettu versio on vuodelta 2019.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LYMPH-SPAIN", "document_id": "spain_lymphedema", "specialty": "Oncology / lymphology", "condition_en": "Breast-cancer-related lymphedema", "condition_fi": "Rintasyöpään liittyvä lymfaturvotus", "direction": "mention_only", "strength_as_reported": "", "evidence_certainty_as_reported": "", "scope": "Laser section on lymphedema; narrative evidence discussion", "summary_en": "The guideline discusses laser studies, possible volume and tissue effects, and the need for further efficacy, safety and dose research; no formal laser recommendation grade was verified.", "summary_fi": "Suositus käsittelee lasertutkimuksia, mahdollisia vaikutuksia tilavuuteen ja kudokseen sekä lisätutkimusten tarvetta tehosta, turvallisuudesta ja annostelusta. Erillistä suositusluokkaa ei vahvistettu.", "locator": "Printed pp. 88–89; references p. 95", "evidence_anchor": "se precisan más estudios para precisar mejor su efectividad", "caveat_en": "Citation mismatch: reference 137, used in the laser discussion, is a trial of low-frequency low-intensity electrotherapy, not LLLT. Its pain / quality-of-life findings are not treated as PBM evidence here.", "caveat_fi": "Viitevirhe: laseriosion viite 137 koskee matalataajuista sähköhoitoa, ei LLLT:tä. Sen kipu- ja elämänlaatutuloksia ei tässä tulkita PBM-näytöksi.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "TMD-KOREA", "document_id": "korean_tmd", "specialty": "Dentistry / orofacial pain", "condition_en": "Temporomandibular disorders", "condition_fi": "Purentaelimistön toimintahäiriöt (TMD)", "direction": "may_consider", "strength_as_reported": "B; grouped physical-therapy recommendation", "evidence_certainty_as_reported": "Moderate; grouped recommendation; LLLT outcome assessments also moderate", "scope": "Korean-medicine physical therapy, including meridian LLLT and TENS", "summary_en": "Physical therapy in Korean medicine should be considered for symptom improvement; meridian LLLT is a component of the assessed therapy group.", "summary_fi": "Korealaisen lääketieteen fysikaalisia hoitoja tulisi harkita oireiden lievittämiseen; meridiaani-LLLT on osa arvioitua hoitoryhmää.", "locator": "§3.7.1; R15; Meridian LLLT meta-analysis", "evidence_anchor": "physical therapy in Korean medicine should be considered to improve symptoms", "caveat_en": "The B grade belongs to R15's physical-therapy group, not a standalone general PBM recommendation. The paper separately rates LLLT pain and mouth-opening evidence as moderate.", "caveat_fi": "B on R15:n fysikaalisten hoitojen yhteissuositus, ei erillinen yleinen PBM-luokitus. Julkaisu arvioi myös erikseen LLLT:n kipu- ja suunavausnäytön kohtalaiseksi.", "intervention": "Meridian low-level laser therapy; grouped with TENS", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ORAL-IRAE-MASCC", "document_id": "mascc_immunotherapy", "specialty": "Oncology / oral care", "condition_en": "Immunotherapy-associated oral lichenoid lesions: acute pain", "condition_fi": "Immunoterapiaan liittyvät suun likenoidimuutokset: akuutti kipu", "direction": "expert_protocol", "strength_as_reported": "Clinical practice statement; no formal PBM-specific grade", "evidence_certainty_as_reported": "No direct efficacy evidence for oral irAEs; extrapolated", "scope": "Acute pain with oral lichen planus / oral lichenoid reaction during immunotherapy", "summary_en": "PBM may help acute pain; the statement advises a protocol assessed in randomized trials and explains that use is extrapolated from other oral conditions.", "summary_fi": "PBM saattaa lievittää akuuttia kipua. Kannanotto neuvoo käyttämään satunnaistetuissa tutkimuksissa arvioitua protokollaa ja kertoo käytön perustuvan muista suusairauksista tehtyyn ekstrapolaatioon.", "locator": "Oral lichen planus / lichenoid reactions; Box 1", "evidence_anchor": "photobiomodulation (PBM) may help with pain management at the acute phase", "caveat_en": "Box 1 explicitly states that efficacy evidence for these interventions in oral immune-related adverse events is absent; this is not direct trial evidence for oral irAEs.", "caveat_fi": "Laatikko 1 toteaa, että näiden interventioiden tehosta suun immuunihaittoihin ei ole näyttöä. Kyse ei ole tämän käyttöaiheen suorasta tutkimusnäytöstä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_statement" }, { "id": "ORAL-GVHD-MASCC", "document_id": "mascc_gvhd", "specialty": "Oncology / oral care", "condition_en": "Oral chronic graft-versus-host disease", "condition_fi": "Suun krooninen käänteishyljintä", "direction": "insufficient_evidence", "strength_as_reported": "No formal PBM recommendation grade", "evidence_certainty_as_reported": "", "scope": "Oral chronic GVHD", "summary_en": "The practice statement notes early PBM evidence but says more research is needed.", "summary_fi": "Kannanotto mainitsee alustavan PBM-näytön mutta toteaa lisätutkimusten tarpeen.", "locator": "Oral mucosal manifestations; topical interventions", "evidence_anchor": "More research is needed about these interventions.", "caveat_en": "PBM is mentioned alongside PUVA/UVB and platelet gel; these modalities are distinct and are not pooled here.", "caveat_fi": "PBM mainitaan PUVA/UVB-hoidon ja verihiutalegeelin rinnalla; kyse on eri hoitomuodoista.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_statement" }, { "id": "OM-NCCN-HISTORICAL", "document_id": "nccn_mucositis", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention", "condition_fi": "Suun mukosiitin ehkäisy", "direction": "mention_only", "strength_as_reported": "No current NCCN CPG grade inferred", "evidence_certainty_as_reported": "", "scope": "HSCT and head/neck radiotherapy settings discussed", "summary_en": "The 2008 NCCN Task Force report reviews preventive LLLT evidence and cites the 2006 MASCC suggestion in transplantation.", "summary_fi": "Vuoden 2008 NCCN-työryhmäraportti käsittelee ehkäisevän LLLT:n näyttöä ja siteeraa MASCC:n vuoden 2006 kantaa kantasolusiirroissa.", "locator": "Low-Level Laser Therapy section", "evidence_anchor": "A preventive role for LLLT has been investigated in 2 settings", "caveat_en": "Historical task-force report, not verification of a current NCCN Clinical Practice Guideline endorsement. Do not count the quoted MASCC statement as an independent panel vote.", "caveat_fi": "Historiallinen työryhmäraportti ei vahvista nykyistä NCCN-hoitosuositusta. Siteerattu MASCC-kanta ei ole riippumaton toinen paneeliarvio.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": true, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "PRESSURE-NPUAP-2014", "document_id": "npuap_pressure_2014", "specialty": "Wounds", "condition_en": "Pressure ulcers", "condition_fi": "Painehaavat", "direction": "against", "strength_as_reported": "Not recommended for routine use; recommendation symbol not interpreted", "evidence_certainty_as_reported": "C", "scope": "Pressure-ulcer treatment; routine use", "summary_en": "Laser is not recommended for routine pressure-ulcer treatment because evidence is insufficient to support or refute it.", "summary_fi": "Laseria ei suositella painehaavojen rutiinihoidoksi, koska näyttö ei riitä sen puolesta tai vastaan.", "locator": "PDF p. 214 / printed p. 212; Laser recommendation 1", "evidence_anchor": "laser therapy is not recommended for routine use at this time", "caveat_en": "Historical 2014 edition, superseded by the 2019 edition already in the collection. The strength-of-recommendation glyph is not converted into a numeric or strong/weak grade.", "caveat_fi": "Historiallinen 2014-versio, jonka korvasi koonnissa jo oleva 2019-versio. Suositusvoiman erikoismerkkiä ei tulkita numeeriseksi tai vahva/heikko-luokaksi.", "intervention": "Laser therapy, including low-level approaches in the evidence discussion", "added_in": "expansion_02", "historical": true, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "VOICE-HEALTHY-CONSENSUS", "document_id": "vocal_consensus", "specialty": "Voice / speech therapy", "condition_en": "Healthy professional voice and vocal fatigue", "condition_fi": "Terve ammattiääni ja äänen väsyminen", "direction": "expert_protocol", "strength_as_reported": "Expert content-validity consensus; CVC 1.00 for healthy voice / fatigue; 0.90 recovery", "evidence_certainty_as_reported": "No GRADE efficacy rating", "scope": "Healthy voice professionals; fatigue, muscle performance and recovery", "summary_en": "Seven experts reached content-validity consensus on PBM use in healthy voice professionals and vocal fatigue/recovery.", "summary_fi": "Seitsemän asiantuntijaa saavutti sisältövaliditeettikonsensuksen PBM:n käytöstä terveillä ääniammattilaisilla sekä äänen väsymiseen ja palautumiseen.", "locator": "Table 2, statements on healthy voice and items 11–13", "evidence_anchor": "I use PBM with voice professionals to reduce symptoms of vocal fatigue.", "caveat_en": "Small expert Delphi consensus; CVC measures agreement/content validity, not clinical benefit, trial certainty or percentage of patients responding.", "caveat_fi": "Pieni Delphi-asiantuntijakonsensus. CVC mittaa yhtenevyyttä ja sisältövaliditeettia, ei hoitotehoa, näytön varmuutta tai hyötyneiden potilaiden osuutta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "VOICE-BEHAVIORAL-CONSENSUS", "document_id": "vocal_consensus", "specialty": "Voice / speech therapy", "condition_en": "Behavioral dysphonia without laryngeal injury", "condition_fi": "Toiminnallinen äänihäiriö ilman kurkunpäävauriota", "direction": "expert_protocol", "strength_as_reported": "CVC 0.81; consensus threshold ≥0.75", "evidence_certainty_as_reported": "No GRADE efficacy rating", "scope": "Behavioral dysphonia without laryngeal injury", "summary_en": "The expert panel reached content-validity consensus on this use.", "summary_fi": "Asiantuntijapaneeli saavutti tätä käyttöä koskevan sisältövaliditeettikonsensuksen.", "locator": "Table 2, item 16", "evidence_anchor": "I use PBM in cases of patients with behavioral dysphonia without laryngeal injury.", "caveat_en": "Consensus on an expert-use statement is not a proven treatment effect.", "caveat_fi": "Asiantuntijoiden käyttölausuman konsensus ei osoita hoitovaikutusta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "VOICE-TENSION-NOCONSENSUS", "document_id": "vocal_consensus", "specialty": "Voice / speech therapy", "condition_en": "Muscle-tension dysphonia", "condition_fi": "Lihasjännitykseen liittyvä äänihäiriö", "direction": "insufficient_evidence", "strength_as_reported": "No consensus; CVC 0.71 below threshold 0.75", "evidence_certainty_as_reported": "No GRADE efficacy rating", "scope": "Muscle-tension dysphonia", "summary_en": "The PBM-use statement did not meet the expert consensus threshold.", "summary_fi": "PBM:n käyttölausuma ei saavuttanut asiantuntijakonsensuksen kynnystä.", "locator": "Table 2, item 14", "evidence_anchor": "I use PBM in cases of patients with dysphonia due to muscle tension.", "caveat_en": "No consensus is not a formal recommendation against treatment.", "caveat_fi": "Konsensuksen puuttuminen ei ole muodollinen kielteinen hoitosuositus.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "VOICE-ORGANIC-NOCONSENSUS", "document_id": "vocal_consensus", "specialty": "Voice / speech therapy", "condition_en": "Structural, organic or neurological voice disorders", "condition_fi": "Rakenteelliset, elimelliset tai neurologiset äänihäiriöt", "direction": "insufficient_evidence", "strength_as_reported": "No consensus; CVC 0.52 / 0.57 / 0.48 / 0.43", "evidence_certainty_as_reported": "No GRADE efficacy rating", "scope": "Behavioral dysphonia with laryngeal injury; organic or neurological dysphonia; head/neck-cancer sequelae", "summary_en": "These PBM-use statements did not meet the expert consensus threshold.", "summary_fi": "Nämä PBM:n käyttölausumat eivät saavuttaneet asiantuntijakonsensuksen kynnystä.", "locator": "Table 2, items 17–20", "evidence_anchor": "I use PBM in cases of patients with dysphonia of neurological origin.", "caveat_en": "Grouped here because all fall below the CVC 0.75 threshold. This does not establish inefficacy.", "caveat_fi": "Ryhmitelty, koska kaikki jäävät CVC-kynnyksen 0,75 alle. Tämä ei osoita tehottomuutta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "RA-ACR-THERMAL-MENTION", "document_id": "acr_ra_integrative", "specialty": "Rheumatology", "condition_en": "Rheumatoid arthritis: thermal-modality group", "condition_fi": "Nivelreuma: lämpöhoitoryhmän lasermaininta", "direction": "mention_only", "strength_as_reported": "Conditional recommendation for thermal-modality group; no PBM-specific grade verified", "evidence_certainty_as_reported": "Very low; thermal-modality group", "scope": "Rheumatoid arthritis; thermal modalities alongside DMARD-based care", "summary_en": "The guideline conditionally recommends thermal modalities and lists laser therapy among examples. A PBM-specific recommendation was not verified.", "summary_fi": "Suositus puoltaa ehdollisesti lämpöhoitojen ryhmää ja mainitsee laserhoidon yhtenä esimerkkinä. PBM-kohtaista suositusta ei vahvistettu.", "locator": "Intervention definitions: Thermal modalities; Recommendations", "evidence_anchor": "paraffin therapy, and laser therapy.", "caveat_en": "Laser type is unspecified; the group's conditional recommendation and very low certainty must not be presented as a verified LLLT-only recommendation. Verified from an authorized guideline summary.", "caveat_fi": "Laserin tyyppiä ei eritellä. Ryhmän ehdollista kantaa ja hyvin matalaa varmuutta ei tule esittää vahvistettuna LLLT:n erillissuosituksena. Tarkistus valtuutetusta suositustiivistelmästä.", "intervention": "Laser therapy; unspecified type within thermal modalities", "added_in": "expansion_02", "historical": false, "checked_on": "2026-10-15", "verification_depth": "licensed_guideline_summary", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "FIBRO-TSPMR", "document_id": "turkish_fibro", "specialty": "Pain", "condition_en": "Fibromyalgia", "condition_fi": "Fibromyalgia", "direction": "insufficient_evidence", "strength_as_reported": "No standalone LLLT recommendation verified; physical-modality group weak positive as part of care", "evidence_certainty_as_reported": "", "scope": "Fibromyalgia; LLLT-specific evidence discussion", "summary_en": "The guideline describes LLLT use as controversial. Its weak positive statement applies to a broader physical-modality group as part of treatment.", "summary_fi": "Suositus kuvaa LLLT:n käyttöä kiistanalaiseksi. Heikko myönteinen kanta koskee laajempaa fysikaalisten hoitojen ryhmää muun hoidon osana.", "locator": "PDF p. 4 / printed p. 114, Physical therapy modalities and Low-level laser therapy", "evidence_anchor": "its use in FM is still controversial", "caveat_en": "The grouped weak recommendation is not transferred to LLLT alone. The section lists favorable small trials while other parts of the guideline note insufficient evidence for laser.", "caveat_fi": "Hoitoryhmän heikkoa suositusta ei siirretä LLLT:n erillissuositukseksi. Osiossa kuvataan pieniä myönteisiä tutkimuksia; muualla lasernäyttö todetaan riittämättömäksi.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-AAPD", "document_id": "aapd_lasers", "specialty": "Pediatric dentistry", "condition_en": "Pediatric oral mucositis", "condition_fi": "Lasten suun mukosiitti", "direction": "mention_only", "strength_as_reported": "No PBM-specific recommendation grade", "evidence_certainty_as_reported": "", "scope": "Children; oral mucositis associated with chemotherapy, radiation or transplantation", "summary_en": "The policy notes that PBM has been used for prevention and treatment of pediatric oral mucositis.", "summary_fi": "Kannanotto mainitsee PBM:n käytön lasten suun mukosiitin ehkäisyyn ja hoitoon.", "locator": "PDF p. 3 / printed p. 143, Background", "evidence_anchor": "PBM therapy has been used in children", "caveat_en": "Describes use and cites pediatric/mucositis guidance; it is not an independent formal prevention-and-treatment endorsement for every pediatric cancer regimen.", "caveat_fi": "Kuvaa käyttöä ja viittaa lasten mukosiittiohjeisiin; tästä ei päätellä erillistä muodollista suositusta kaikkien lasten syöpähoitojen mukosiitin ehkäisyyn ja hoitoon.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "policy_statement" }, { "id": "PAIN-AAPD", "document_id": "aapd_lasers", "specialty": "Pediatric dentistry", "condition_en": "Postsurgical or traumatic oral pain; cavity preparation", "condition_fi": "Leikkauksen tai vamman jälkeinen suukipu; kaviteetin preparointi", "direction": "descriptive_support", "strength_as_reported": "No PBM-specific recommendation grade", "evidence_certainty_as_reported": "", "scope": "Pediatric oral pain; nonthermal PBM discussion", "summary_en": "The policy says PBM may reduce postsurgical/traumatic oral pain and pain during cavity preparation.", "summary_fi": "Kannanoton mukaan PBM saattaa vähentää leikkauksen tai vamman jälkeistä suukipua sekä preparointiin liittyvää kipua.", "locator": "PDF p. 3 / printed p. 143, Background", "evidence_anchor": "may reduce postsurgical or traumatic oral pain", "caveat_en": "Narrative possibility, not a graded clinical recommendation. Subsequent discussion of hard-tissue laser analgesia involves additional laser types and mechanisms.", "caveat_fi": "Kuvaileva mahdollisuus, ei luokiteltu hoitosuositus. Myöhempi kovakudoslaserin analgesiaa käsittelevä teksti koskee myös muita lasereita ja mekanismeja.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "policy_statement" }, { "id": "ULCERS-AAPD", "document_id": "aapd_lasers", "specialty": "Pediatric dentistry", "condition_en": "Aphthous ulcers and herpetic oral lesions", "condition_fi": "Aftat ja suun herpesmuutokset", "direction": "descriptive_support", "strength_as_reported": "No laser-specific recommendation grade", "evidence_certainty_as_reported": "", "scope": "Children; pain and inflammation from aphthous ulcers / herpetic lesions", "summary_en": "The policy describes possible pain and inflammation relief with PBM and other laser modalities, while requesting better pediatric parameters.", "summary_fi": "Kannanotto kuvaa PBM:n ja muiden lasermenetelmien mahdollista kipu- ja tulehdushyötyä, mutta toteaa lasten hoitoparametrien lisätutkimustarpeen.", "locator": "PDF p. 3 / printed p. 143, Background", "evidence_anchor": "more studies are needed to establish the laser type and therapeutic parameters", "caveat_en": "Grouped PBM, erbium and CO2 laser wording; no single PBM device or dose is endorsed.", "caveat_fi": "Teksti ryhmittelee PBM:n, erbium- ja CO2-laserit; yksittäistä PBM-laitetta tai annosta ei hyväksytä tällä perusteella.", "intervention": "PBM plus other laser types; mixed intervention statement", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "policy_statement" }, { "id": "OM-AFSOS-2015", "document_id": "afsos_mucites", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention: quoted MASCC guidance", "condition_fi": "Suun mukosiitin ehkäisy: siteerattu MASCC-ohje", "direction": "mention_only", "strength_as_reported": "MASCC 2014 recommendation/suggestion reproduced; no independent AFSOS grade", "evidence_certainty_as_reported": "", "scope": "Intensive chemotherapy with/without total-body irradiation; head/neck RT without concurrent chemotherapy", "summary_en": "The informational slide reproduces MASCC 2014: recommended in intensive-chemotherapy settings and suggested for head/neck RT without concurrent chemotherapy.", "summary_fi": "Informatiivinen dia toistaa MASCC:n 2014-kannan: suositellaan intensiivisen solunsalpaajahoidon tilanteissa ja ehdotetaan pään ja kaulan sädehoidossa ilman samanaikaista solunsalpaajahoitoa.", "locator": "Slide / PDF p. 13, Point sur les autres moyens de prévention", "evidence_anchor": "cette planche constitue une synthèse à titre d’information", "caveat_en": "An explicitly attributed reproduction of MASCC; not a second independent panel vote or a blanket recommendation for all chemotherapy.", "caveat_fi": "Nimenomaisesti MASCC:n kannan toisto, ei toinen riippumaton paneeliarvio eikä yleinen suositus kaikkeen solunsalpaajahoitoon.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-AFSOS-RT-2020", "document_id": "afsos_oral_rt", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis during radiotherapy", "condition_fi": "Sädehoitoon liittyvä suun mukosiitti", "direction": "may_consider", "strength_as_reported": "Possible therapeutic option; ungraded", "evidence_certainty_as_reported": "", "scope": "During radiotherapy; oral mucositis section", "summary_en": "Lists low-energy laser as another possible therapy and directs readers to the AFSOS mucositis reference.", "summary_fi": "Mainitsee matalaenergisen laserin muuna mahdollisena hoitona ja ohjaa AFSOS:n mukosiittiohjeeseen.", "locator": "PDF p. 10, During radiotherapy / Mucites", "evidence_anchor": "Autre thérapeutique possible", "caveat_en": "Brief cross-reference; no additional laser-specific grade or protocol is supplied here.", "caveat_fi": "Lyhyt ristiviittaus; tässä ei anneta uutta laserkohtaista luokkaa tai protokollaa.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "TASTE-AFSOS", "document_id": "afsos_taste", "specialty": "Oncology / oral care", "condition_en": "Taste disturbances associated with head and neck cancer treatment", "condition_fi": "Pään ja kaulan syöpähoitoihin liittyvät makuhäiriöt", "direction": "descriptive_support", "strength_as_reported": "No laser-specific grade", "evidence_certainty_as_reported": "", "scope": "Mucositis-associated taste disturbance in head/neck cancer care", "summary_en": "The guidance lists low-intensity/energy laser to reduce mucositis and says it may also limit taste disturbance.", "summary_fi": "Ohje mainitsee matalatehoisen ja -energisen laserin mukosiitin vähentämiseen ja toteaa sen saattavan myös rajoittaa makuhäiriöitä.", "locator": "PDF p. 19, mouth-care recommendations", "evidence_anchor": "peut limiter les troubles du goût", "caveat_en": "Cautious narrative wording; no evidence grade or demonstration of a direct independent effect on taste is provided.", "caveat_fi": "Varovainen tekstimaininta; näytön luokkaa tai osoitusta suorasta, mukosiitista riippumattomasta makuvaikutuksesta ei anneta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RD-AFSOS-CETUXIMAB", "document_id": "afsos_skin", "specialty": "Oncology / dermatology", "condition_en": "Skin toxicity with radiotherapy plus cetuximab", "condition_fi": "Sädehoidon ja setuksimabin yhdistelmän ihohaitat", "direction": "mention_only", "strength_as_reported": "Under evaluation; no therapeutic recommendation grade", "evidence_certainty_as_reported": "", "scope": "Prevention and treatment in combined RT + cetuximab", "summary_en": "Low-energy laser is described as under evaluation in this combined-treatment setting.", "summary_fi": "Matalaenerginen laser kuvataan tässä yhdistelmähoidossa arvioitavana menetelmänä.", "locator": "PDF p. 12", "evidence_anchor": "le laser de basse énergie est en cours d’évaluation", "caveat_en": "Investigation status is not an endorsement for prevention or treatment.", "caveat_fi": "Tutkimusvaihe ei ole ehkäisy- tai hoitosuositus.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RD-AFSOS-ESTABLISHED", "document_id": "afsos_skin", "specialty": "Oncology / dermatology", "condition_en": "Established grade I–II radiation dermatitis", "condition_fi": "Todettu I–II-asteen sädeihottuma", "direction": "mention_only", "strength_as_reported": "Under evaluation; no therapeutic recommendation grade", "evidence_certainty_as_reported": "", "scope": "Established acute grade I / II skin reaction", "summary_en": "Lists low-energy laser as under evaluation in the grade I and II management slides.", "summary_fi": "I- ja II-asteen hoitodioissa matalaenerginen laser on arvioitavana menetelmänä.", "locator": "PDF pp. 16–17", "evidence_anchor": "Le laser basse énergie est en cours d’évaluation.", "caveat_en": "Does not refer to the vascular pulsed-dye laser discussed later for telangiectasia.", "caveat_fi": "Tämä ei tarkoita myöhemmin telangiektasioihin kuvattua verisuonilaseria.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RD-ESTRO-PREVENT", "document_id": "estro_rd", "specialty": "Oncology / dermatology", "condition_en": "Prevention of higher-grade radiation dermatitis", "condition_fi": "Vaikeamman sädeihottuman ehkäisy", "direction": "may_consider", "strength_as_reported": "Conditional recommendation", "evidence_certainty_as_reported": "QoE L2", "scope": "Radiation-induced dermatitis prevention; much of supporting PBM evidence is from breast irradiation", "summary_en": "PBM or low-level laser may be used to prevent higher grades of radiation-induced dermatitis.", "summary_fi": "PBM:ää tai matalatehoista laseria voidaan käyttää vaikeampiasteisen sädeihottuman ehkäisyyn.", "locator": "Table 5; General recommendations / Prevention", "evidence_anchor": "Photo-biomodulation or low-level laser therapy may be used to prevent higher grades of RID", "caveat_en": "Prevention is distinct from treatment of an established reaction; retain the evidence's breast-cancer emphasis.", "caveat_fi": "Ehkäisy ja todetun ihoreaktion hoito ovat eri käyttötilanteita; huomioi näytön painottuminen rintasyöpään.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "WOUND-FDI", "document_id": "fdi_lasers", "specialty": "Dentistry / oral care", "condition_en": "Oral wound healing: general PBM mention", "condition_fi": "Suun haavojen paraneminen: yleinen PBM-maininta", "direction": "descriptive_support", "strength_as_reported": "No PBM-specific treatment grade", "evidence_certainty_as_reported": "", "scope": "General context in a laser education / training / safety policy", "summary_en": "The policy context lists improved wound healing during PBM among possible advantages of dental laser use.", "summary_fi": "Kannanoton taustateksti mainitsee PBM:n aikaisen haavan paranemisen edistymisen yhtenä hammaslaserien mahdollisena etuna.", "locator": "Context paragraph", "evidence_anchor": "improvement of wound healing during photobiomodulation", "caveat_en": "FDI's policy concerns education, training and safety; it does not give a condition-specific clinical PBM recommendation.", "caveat_fi": "FDI:n kannanotto koskee koulutusta ja turvallisuutta; se ei anna käyttöaihekohtaista kliinistä PBM-suositusta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "policy_statement" }, { "id": "AMD-DOG-2025", "document_id": "dog_amd", "specialty": "Ophthalmology", "condition_en": "Nonexudative age-related macular degeneration", "condition_fi": "Kuiva silmänpohjan ikärappeuma", "direction": "against", "strength_as_reported": "Use only within clinical studies; no formal numeric grade", "evidence_certainty_as_reported": "", "scope": "PBM for AMD; statement as of 4 July 2025", "summary_en": "The societies do not issue a treatment recommendation and state that PBM should currently be performed only in clinical studies.", "summary_fi": "Järjestöt eivät anna myönteistä hoitosuositusta ja toteavat, että PBM:ää tulisi käyttää tässä vaiheessa vain kliinisissä tutkimuksissa.", "locator": "PDF p. 2, conclusion", "evidence_anchor": "Die Behandlung sollte aktuell nur im Rahmen klinischer Studien durchgeführt werden.", "caveat_en": "The position cites unproven efficacy and possible risks. This research-only restriction is not inferred from device regulatory status.", "caveat_fi": "Kannanotto perustelee tutkimusrajausta osoittamattomalla teholla ja mahdollisilla riskeillä. Laitteen viranomaisasema on erillinen asia.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "RD-SCOR-2020", "document_id": "scor_rd", "specialty": "Oncology / dermatology", "condition_en": "Radiation dermatitis prevention", "condition_fi": "Sädeihottuman ehkäisy", "direction": "against", "strength_as_reported": "Not recommended at this time; ungraded PBMT statement", "evidence_certainty_as_reported": "", "scope": "2020 UK guideline; uncertainty about modern hypofractionated breast RT and long-term outcomes", "summary_en": "The guideline explicitly does not recommend PBMT at that time, despite promising findings in conventionally fractionated breast irradiation.", "summary_fi": "Ohje ei tuolloin suosittele PBMT:tä, vaikka tavanomaisesti fraktioidussa rinnan sädehoidossa on lupaavia tuloksia.", "locator": "§5.5.2; PDF p. 23 / printed p. 21", "evidence_anchor": "these guidelines do not recommend the use of PBMT at this time", "caveat_en": "Edition 2020, review scheduled for 2025; newer SCoR edition was not verified. ESTRO 2025 is a separate, later conditional positive statement.", "caveat_fi": "Versio 2020, tarkistus oli ajoitettu vuoteen 2025; uudempaa SCoR-versiota ei vahvistettu. ESTRO:n 2025 ehdollinen myönteinen kanta on erillinen myöhempi ohje.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RD-MEXICO-2022", "document_id": "mexico_rd", "specialty": "Oncology / dermatology", "condition_en": "Radiation dermatitis prevention", "condition_fi": "Sädeihottuman ehkäisy", "direction": "insufficient_evidence", "strength_as_reported": "Further research before recommendation; ungraded", "evidence_certainty_as_reported": "", "scope": "Prophylactic PBMT", "summary_en": "PBMT is an emerging intervention; the consensus requests more long-term research before recommending prophylactic use.", "summary_fi": "PBMT kuvataan kehittyväksi menetelmäksi; konsensus edellyttää lisää pitkäaikaistutkimusta ennen ehkäisevän käytön suosittelemista.", "locator": "Treatment / emerging approaches, before Conclusions", "evidence_anchor": "further research is needed on long-term effects", "caveat_en": "Does not establish ineffectiveness and is not a positive recommendation.", "caveat_fi": "Lisänäytön tarve ei osoita tehottomuutta eikä ole myönteinen suositus.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "society_consensus" }, { "id": "MIH-EAPD", "document_id": "eapd_mih", "specialty": "Pediatric dentistry", "condition_en": "Hypersensitivity in molar-incisor hypomineralisation", "condition_fi": "MIH-kiillehäiriöön liittyvä hampaiden yliherkkyys", "direction": "may_consider", "strength_as_reported": "Conditional; grouped interventions", "evidence_certainty_as_reported": "Low; grouped GRADE assessment", "scope": "MIH-affected teeth; group includes topical agents, ozone and laser", "summary_en": "Table 10 conditionally permits a group including laser to reduce hypersensitivity.", "summary_fi": "Taulukko 10 sallii ehdollisesti laserin sisältävän hoitoryhmän MIH-hampaiden yliherkkyyden lievittämiseen.", "locator": "Table 10; PDF p. 14; narrative p. 13", "evidence_anchor": "ozone/laser can be used to reduce the symptoms of hypersensitivity", "caveat_en": "The conditional/low grades belong to the group. The narrative says evidence cannot support specific interventions because of bias, short follow-up and small samples; a laser-only recommendation is not inferred.", "caveat_fi": "Ehdollinen kanta ja matala varmuus koskevat ryhmää. Tekstiosio on varovaisempi tutkimusharhan, lyhyen seurannan ja pienten otosten vuoksi; laserin erillissuositusta ei päätellä.", "intervention": "LLLT in narrative; laser in grouped table", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "EB-ORAL-LESIONS", "document_id": "eb_oral", "specialty": "Dentistry / oral care", "condition_en": "Oral ulcers in dystrophic epidermolysis bullosa", "condition_fi": "Dystrofisen rakkulaihotaudin suuhaavaumat", "direction": "descriptive_support", "strength_as_reported": "No isolated LLLT recommendation or grade", "evidence_certainty_as_reported": "", "scope": "Seven-patient pilot of cord-blood platelet gel plus LLLT, discussed in an oral-care guideline", "summary_en": "The guideline describes improvements in pain and lesion size in a small combined-treatment pilot.", "summary_fi": "Ohje kuvaa kivun ja haavakoon paranemista pienessä yhdistelmähoidon pilottitutkimuksessa.", "locator": "§3.1.7 Oral bullae and ulcerations", "evidence_anchor": "cord blood platelet gel (CBPG) and low‐level laser therapy (LLLT)", "caveat_en": "Case-series evidence with a co-intervention; it cannot establish the independent effect of PBM or a generally effective EB regimen.", "caveat_fi": "Tapaussarja ja samanaikainen toinen hoito eivät osoita PBM:n itsenäistä vaikutusta tai yleisesti tehokasta rakkulaihotaudin hoitoa.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "APHTHAE-S2K", "document_id": "s2k_aphthae", "specialty": "Dentistry / oral care", "condition_en": "Recurrent aphthous lesions", "condition_fi": "Toistuvat aftat", "direction": "may_consider", "strength_as_reported": "Therapeutic option; no PBM-only grade", "evidence_certainty_as_reported": "", "scope": "Recurrent aphthous lesions; mixed CO2, Nd:YAG and diode laser approaches", "summary_en": "The guideline presents laser as a therapeutic option with possible pain relief and faster healing, while stating that no standard laser application can be identified.", "summary_fi": "Ohje esittää laserin hoitovaihtoehtona kivun lievittämiseen ja paranemisen nopeuttamiseen, mutta toteaa, ettei vakioprotokollaa voida tunnistaa.", "locator": "Printed pp. 18–19; treatment pathway and commentary", "evidence_anchor": "ist eine therapeutische", "caveat_en": "Mixed laser types and protocols; no standardized PBM-only regimen or formal laser-specific grade is verified.", "caveat_fi": "Eri lasertyyppejä ja protokollia; yhtenäistä PBM-protokollaa tai erillistä muodollista laserluokitusta ei vahvistettu.", "intervention": "Mixed laser modalities; LLLT among cited clinical evidence", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "RAS-INDIA", "document_id": "ras_india", "specialty": "Dentistry / oral care", "condition_en": "Recurrent aphthous stomatitis", "condition_fi": "Toistuva aftoosi stomatiitti", "direction": "descriptive_support", "strength_as_reported": "No laser-specific grade", "evidence_certainty_as_reported": "", "scope": "Aphthous pain / healing; mixed laser evidence", "summary_en": "The expert consensus favorably discusses laser treatment, including diode low-level mode, for pain relief and healing time.", "summary_fi": "Asiantuntijakonsensus käsittelee myönteisesti laserhoitoa, mukaan lukien diodin matalatehoinen toimintatapa, kivun ja paranemisajan kannalta.", "locator": "Treatment narrative, paragraph on lasers", "evidence_anchor": "diode laser (low-level laser treatment mode)", "caveat_en": "Mixes ablative Nd:YAG, nonablative CO2 and diode low-level modes. The narrative evidence summary is not a PBM-specific graded recommendation.", "caveat_fi": "Sekoittaa ablatiivisen Nd:YAG:n, ei-ablatiivisen CO2:n ja diodin matalatehoisen käytön. Näyttötiivistelmä ei ole PBM:n erillinen luokiteltu suositus.", "intervention": "Diode LLLT plus other laser modes", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "TINNITUS-AAOHNS-2026", "document_id": "aao_tinnitus_2026", "specialty": "Audiology / otolaryngology", "condition_en": "Tinnitus: low-level laser in research agenda", "condition_fi": "Tinnitus: matalatehoinen laser tutkimusohjelmassa", "direction": "mention_only", "strength_as_reported": "Research agenda; therapeutic recommendation not verified", "evidence_certainty_as_reported": "", "scope": "2026 guideline update; future research into neuromodulation methods", "summary_en": "The official research agenda names low-level laser and calls for further long-term safety, efficacy and clinical-setting research.", "summary_fi": "Virallinen tutkimusohjelma nimeää matalatehoisen laserin ja kehottaa tutkimaan pitkäaikaista turvallisuutta, tehoa ja sopivaa kliinistä käyttötilannetta.", "locator": "Research agenda item 27 (KAS 14); official page dated 9 October 2026", "evidence_anchor": "low‐level laser therapy, and bimodal stimulation", "caveat_en": "This is a research-priority mention; neither recommendation for nor against clinical LLLT is inferred from the inaccessible full guideline.", "caveat_fi": "Kyse on tutkimustarpeen maininnasta. Kokonaisen ohjeen kliinistä LLLT-kantaa ei päätellä tästä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "official_update_note_only", "final_grade_recheck_needed": false, "recommendation_class": "guideline_update_note" }, { "id": "DENTINE-MEA", "document_id": "dentine_mea", "specialty": "Dentistry / oral care", "condition_en": "Dentine hypersensitivity", "condition_fi": "Hampaiden yliherkkyys", "direction": "may_consider", "strength_as_reported": "Expert consensus; no separate LLLT-only strength", "evidence_certainty_as_reported": "AI in the source's evidence-grade/level column; mixed lasers", "scope": "In-office management; high- and low-power laser options", "summary_en": "The consensus describes lasers as an option, including diode lasers at high and low power; effectiveness depends on the laser used.", "summary_fi": "Konsensus kuvaa laserit hoitovaihtoehdoksi ja sisältää sekä suuri- että matalatehoiset diodilaserit; teho riippuu käytetystä laserista.", "locator": "Table 2, in-office treatment / laser row", "evidence_anchor": "diode laser (high and low power)", "caveat_en": "The AI notation is retained as reported for a mixed-laser row; it is not converted into high-certainty GRADE evidence for PBM alone.", "caveat_fi": "AI-merkintä säilytetään eri laserien yhteisrivin lähdeluokituksena; sitä ei tulkita PBM:n erilliseksi korkeaksi GRADE-varmuudeksi.", "intervention": "Mixed laser modalities including low-power diode", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "DENTINE-ISP", "document_id": "isp_dentine", "specialty": "Dentistry / oral care", "condition_en": "Dentine hypersensitivity: laser treatment guidance", "condition_fi": "Hampaiden yliherkkyys: laserhoidon käytännön ohje", "direction": "expert_protocol", "strength_as_reported": "Good clinical practice guidance; no formal LLLT-specific grade", "evidence_certainty_as_reported": "", "scope": "In-office laser option; low-power diode and high-power modalities discussed", "summary_en": "The recommendations give a practical laser protocol, including diode options, while acknowledging no gold standard for parameters.", "summary_fi": "Suositukset antavat käytännön laserprotokollan myös diodille mutta toteavat, ettei parametreille ole kultastandardia.", "locator": "Occlusive approach by laser / Laser parameter settings", "evidence_anchor": "There is lack of evidence to suggest a gold standard for laser parameter settings", "caveat_en": "The protocol mixes low- and high-power mechanisms. It is not a universal validated PBM dose or a standalone formal efficacy grade.", "caveat_fi": "Protokolla sisältää matala- ja suuritehoisia mekanismeja. Se ei ole yleinen validoitu PBM-annos eikä muodollinen erillinen teholuokitus.", "intervention": "Low-power diode PBM and high-power lasers discussed separately", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "VAGINAL-SENORIF", "document_id": "senorif_breast", "specialty": "Oncology / supportive care", "condition_en": "Vulvovaginal dryness in breast-cancer endocrine therapy care", "condition_fi": "Rintasyövän hormonihoitoon liittyvä ulkosynnyttimien ja emättimen kuivuus", "direction": "against", "strength_as_reported": "Not advised; grouped physical therapies; ungraded", "evidence_certainty_as_reported": "", "scope": "Breast-cancer supportive care; vulvovaginal dryness", "summary_en": "The reference does not advise laser or a group of physical therapies explicitly including PBM because clear benefit has not been demonstrated; it advises specialist assessment.", "summary_fi": "Ohje ei suosittele laseria tai PBM:n nimenomaisesti sisältävää fysikaalisten hoitojen ryhmää, koska selvää hyötyä ei ole osoitettu; se ohjaa erikoisarvioon.", "locator": "Table 27; PDF pp. 161–162", "evidence_anchor": "photobiomodulation, lipofilling", "caveat_en": "Regional breast-cancer guidance, not a blanket statement on all gynecological PBM or other cancer supportive-care uses.", "caveat_fi": "Alueellinen rintasyöpäohje; kantaa ei yleistetä kaikkeen gynekologiseen PBM-hoitoon tai muihin syövän tukihoitoihin.", "intervention": "PBM explicitly listed alongside laser, radiofrequency and lipofilling", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-POGO-RT-NONCARCINOMA", "document_id": "pogo_mucositis", "specialty": "Pediatric oncology", "condition_en": "Oral mucositis prevention: pediatric head/neck RT for noncarcinoma", "condition_fi": "Lasten suun mukosiitin ehkäisy muun pään ja kaulan syövän kuin karsinooman sädehoidossa", "direction": "may_consider", "strength_as_reported": "Conditional recommendation", "evidence_certainty_as_reported": "Moderate-quality evidence", "scope": "Children receiving head/neck RT for cancers other than carcinoma, e.g. rhabdomyosarcoma; intraoral red-light PBM 620–750 nm", "summary_en": "Consider intraoral PBM; the panel extrapolates benefits from carcinoma radiotherapy because direct data for other pediatric head/neck cancers were unavailable.", "summary_fi": "Suunsisäistä PBM:ää voidaan harkita. Paneeli yleistää karsinooman sädehoidosta saatua hyötyä, koska muista lasten pään ja kaulan syövistä ei ollut suoraa aineistoa.", "locator": "COG official endorsed-guideline summary, PDF p. 44, recommendation 5", "evidence_anchor": "radiotherapy for head and neck cancers other than carcinoma", "caveat_en": "Same POGO 2021 guideline as the two existing strong/high-quality rows; a separate indirect-evidence setting, not a new document.", "caveat_fi": "Sama POGO:n 2021-suositus kuin kaksi aiempaa vahvan ja korkealaatuisen näytön riviä; erillinen epäsuoran näytön käyttötilanne, ei uusi asiakirja.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_03", "historical": false, "checked_on": "2026-10-16", "verification_depth": "official_recommendation_summary", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-OARSI-KNEE-NOCOMORB", "document_id": "oarsi_2019", "specialty": "Musculoskeletal", "condition_en": "Knee osteoarthritis without comorbidities", "condition_fi": "Polven nivelrikko ilman liitännäissairauksia", "direction": "against", "strength_as_reported": "Level 4B; conditional; 60–74% against", "evidence_certainty_as_reported": "", "scope": "Knee OA without the specified comorbidities", "summary_en": "The official supplement places laser therapy in conditional-against Level 4B for this subgroup.", "summary_fi": "Virallinen liite sijoittaa laserhoidon tässä potilasryhmässä ehdollisesti kielteiseen luokkaan 4B.", "locator": "Official Supplementary Table 5; Level 4B / No Comorbidities", "evidence_anchor": "Level 4B", "caveat_en": "Laser class is unspecified in the table. This subgroup must not be conflated with the Level 3 comorbidity groups or hip/polyarticular OA.", "caveat_fi": "Taulukko ei erittele laserluokkaa. Tätä ryhmää ei yhdistetä luokan 3 liitännäissairausryhmiin tai lonkka-/moninivelrikkoon.", "intervention": "Laser therapy; class unspecified in recommendation table", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_and_official_supplements", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-OARSI-KNEE-COMORB", "document_id": "oarsi_2019", "specialty": "Musculoskeletal", "condition_en": "Knee osteoarthritis with GI/CV comorbidity or frailty", "condition_fi": "Polven nivelrikko ja ruoansulatuskanavan tai sydän- ja verisuonisairaus tai hauraus", "direction": "insufficient_evidence", "strength_as_reported": "Level 3; conditional; 40–59% in favor", "evidence_certainty_as_reported": "", "scope": "Knee OA with gastrointestinal or cardiovascular comorbidity, or frailty", "summary_en": "Laser is placed at Level 3 with 40–59% voting in favor. This is below the guideline's recommended-treatment tiers 1A, 1B and 2.", "summary_fi": "Laser on luokassa 3, jossa 40–59 % äänesti puolesta. Se jää ohjeen varsinaisten suositeltujen hoitojen luokkien 1A, 1B ja 2 alle.", "locator": "Official Supplementary Table 5; Level 3; GI/CV merged column and Frailty column", "evidence_anchor": "Level 3- 40%-59%", "caveat_en": "Table labels the level Conditional; no clear positive consensus is inferred. GI and CV share a merged cell; frailty is a separate adjacent cell.", "caveat_fi": "Taulukko nimeää luokan ehdolliseksi; siitä ei päätellä selvää myönteistä konsensusta. GI- ja CV-sarake on yhdistetty, hauraus erillinen viereinen sarake.", "intervention": "Laser therapy; class unspecified in recommendation table", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_and_official_supplements", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-OARSI-KNEE-WIDESPREAD", "document_id": "oarsi_2019", "specialty": "Musculoskeletal", "condition_en": "Knee osteoarthritis with widespread pain/depression", "condition_fi": "Polven nivelrikko sekä laaja-alainen kipu tai masennus", "direction": "against", "strength_as_reported": "Level 4A; conditional; ≥75% against and >50% conditional", "evidence_certainty_as_reported": "", "scope": "Knee OA with widespread pain and/or depression", "summary_en": "Laser is listed in the conditional-against Level 4A subgroup.", "summary_fi": "Laser on tässä potilasryhmässä ehdollisesti kielteisessä luokassa 4A.", "locator": "Official Supplementary Table 5; Level 4A / Widespread pain–Depression", "evidence_anchor": "Level 4A-", "caveat_en": "The row differs from the recommendations for other knee-OA comorbidity groups. Device class is not specified.", "caveat_fi": "Kanta eroaa muiden polvinivelrikon potilasryhmien kannoista. Laiteluokkaa ei eritellä.", "intervention": "Laser therapy; class unspecified in recommendation table", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_and_official_supplements", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-OARSI-HIP-POLY", "document_id": "oarsi_2019", "specialty": "Musculoskeletal", "condition_en": "Hip and polyarticular osteoarthritis", "condition_fi": "Lonkan nivelrikko ja moninivelrikko", "direction": "against", "strength_as_reported": "Strong recommendation against", "evidence_certainty_as_reported": "", "scope": "Hip or polyarticular OA across listed comorbidity groups", "summary_en": "Supplementary Table 8 strongly recommends against laser therapy for hip and polyarticular OA.", "summary_fi": "Liitetaulukko 8 suosittelee vahvasti laserhoitoa vastaan lonkka- ja moninivelrikossa.", "locator": "Official Supplementary Table 8; Laser Therapy row", "evidence_anchor": "Treatments that were Strongly Recommended Against", "caveat_en": "This is the panel's recommendation and rationale; it is not generalized to all knee OA or presented as an independently proven biological conclusion.", "caveat_fi": "Tämä on paneelin kanta ja perustelu. Sitä ei yleistetä kaikkeen polvinivelrikkoon eikä esitetä riippumattomasti osoitettuna biologisena päätelmänä.", "intervention": "Laser therapy; class unspecified in recommendation table", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_and_official_supplements", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-OARSI-LASER-ACUP", "document_id": "oarsi_2019", "specialty": "Musculoskeletal", "condition_en": "Knee, hip or polyarticular OA: laser acupuncture", "condition_fi": "Polvi-, lonkka- tai moninivelrikko: laserakupunktio", "direction": "against", "strength_as_reported": "Strong recommendation against", "evidence_certainty_as_reported": "", "scope": "Laser acupuncture across knee, hip and polyarticular OA and comorbidity groups", "summary_en": "The guideline strongly recommends against laser acupuncture.", "summary_fi": "Ohje suosittelee vahvasti laserakupunktiota vastaan.", "locator": "Official Supplementary Table 8; Laser Acupuncture row", "evidence_anchor": "Laser Acupuncture", "caveat_en": "Laser acupuncture is a separate intervention from the table's generic laser-therapy category.", "caveat_fi": "Laserakupunktio on eri interventio kuin taulukon yleinen laserhoitoluokka.", "intervention": "Laser acupuncture", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_and_official_supplements", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "DFU-AUSTRALIA-2021", "document_id": "australia_wound_2021", "specialty": "Wound care / diabetes", "condition_en": "Diabetes-related foot ulcer healing", "condition_fi": "Diabetekseen liittyvän jalkahaavan paraneminen", "direction": "against", "strength_as_reported": "Weak / conditional; grouped physical modalities", "evidence_certainty_as_reported": "Low; grouped assessment", "scope": "Difficult-to-heal diabetes-related foot ulcers; physical modalities versus best standard care", "summary_en": "The panel suggests not preferring physical-environment interventions over best standard care; laser is included in the clinical question and rationale.", "summary_fi": "Paneeli ehdottaa, ettei fyysiseen ympäristöön vaikuttavia hoitoja aseteta parhaan tavanomaisen hoidon edelle; laser sisältyy kysymykseen ja perusteluihin.", "locator": "Recommendation 12; Clinical question and Summary justification", "evidence_anchor": "We suggest not using agents reported to have an effect on wound healing", "caveat_en": "The Australian adaptation weakens IWGDF 2019's grouped recommendation. No isolated laser-only certainty grade is inferred.", "caveat_fi": "Australialainen sovitus lieventää IWGDF:n 2019 ryhmäsuositusta. Erillistä laserkohtaista varmuusluokkaa ei päätellä.", "intervention": "Physical therapies including laser, shockwaves, ultrasound, magnetism and electric current", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "MRONJ-CHINA-2024", "document_id": "china_mronj_2024", "specialty": "Dentistry / oral surgery", "condition_en": "Medication-related osteonecrosis of the jaw", "condition_fi": "Lääkkeisiin liittyvä leukaluun osteonekroosi", "direction": "descriptive_support", "strength_as_reported": "No formal LLLT-specific grade", "evidence_certainty_as_reported": "", "scope": "LLLT as an adjunct to antibiotics and/or surgery; MRONJ", "summary_en": "The consensus discusses possible pain, edema and lesion-size benefit with LLLT, but explicitly notes a lack of high-quality studies.", "summary_fi": "Konsensus käsittelee mahdollista kipu-, turvotus- ja vauriokokohyötyä mutta toteaa korkealaatuisten tutkimusten puutteen.", "locator": "§2.5.2.5 Ozone and low-level laser therapy", "evidence_anchor": "there still lacks high quality study evaluating the therapeutic effects of LLLT", "caveat_en": "Reported improvements involve combined therapy and heterogeneous laser protocols; no independent PBM effect or cure rate is inferred.", "caveat_fi": "Kuvatut tulokset koskevat yhdistelmähoitoja ja vaihtelevia protokollia; PBM:n itsenäistä vaikutusta tai paranemisprosenttia ei päätellä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "MRONJ-ITALY-PALLIATIVE", "document_id": "italy_mronj_2023", "specialty": "Dentistry / oral surgery", "condition_en": "MRONJ: nonsurgical palliative care", "condition_fi": "Leukaluun lääkeosteonekroosin palliatiivinen konservatiivinen hoito", "direction": "may_consider", "strength_as_reported": "Adjunctive option; ungraded", "evidence_certainty_as_reported": "", "scope": "All MRONJ stages when surgery is contraindicated or declined; symptomatic care", "summary_en": "Lists LLLT/laser PBM as an adjunct to nonsurgical care for palliation and exfoliation of necrotic bone.", "summary_fi": "Luettelee LLLT:n/laser-PBM:n konservatiivisen hoidon lisävaihtoehdoksi oireiden lievittämiseen ja nekroottisen luun irtoamisen yhteyteen.", "locator": "Table 7(c), nonsurgical protocol and footnote c", "evidence_anchor": "biostimulation with ozone or low- level laser", "caveat_en": "Restricted nonsurgical/palliative setting. Laser-assisted bone surgery elsewhere in the table is not PBM.", "caveat_fi": "Rajattu konservatiivinen ja palliatiivinen käyttötilanne. Muualla taulukossa kuvattu laseravusteinen luukirurgia ei ole PBM:ää.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "position_paper" }, { "id": "OA-ARGENTINA-KNEE", "document_id": "argentina_oa_2010", "specialty": "Musculoskeletal", "condition_en": "Knee osteoarthritis: pain and function", "condition_fi": "Polven nivelrikko: kipu ja toimintakyky", "direction": "no_benefit", "strength_as_reported": "Narrative evidence statement; no separate laser grade", "evidence_certainty_as_reported": "", "scope": "Knee OA; assessment in the 2010 guideline", "summary_en": "The 2010 summary states that laser therapy does not improve the pain/function parameters discussed.", "summary_fi": "Vuoden 2010 yhteenveto toteaa, ettei laserhoito paranna käsiteltyjä kipu- ja toimintakykymuuttujia.", "locator": "PDF p. 35 / printed p. 34, Physical modalities summary", "evidence_anchor": "Laserterapia, Magnetoterapia y Electroestimulación no mejoran estos parámetros", "caveat_en": "Historical statement; the summary does not specify a single laser protocol or precise follow-up interval.", "caveat_fi": "Historiallinen kannanotto; yhteenveto ei määritä yksittäistä laserprotokollaa tai tarkkaa seuranta-aikaa.", "intervention": "Laser therapy; LLLT in cited evidence", "added_in": "expansion_04", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "OA-ARGENTINA-HAND", "document_id": "argentina_oa_2010", "specialty": "Musculoskeletal", "condition_en": "Hand osteoarthritis", "condition_fi": "Käsien nivelrikko", "direction": "no_benefit", "strength_as_reported": "Narrative evidence statement; no separate laser grade", "evidence_certainty_as_reported": "", "scope": "Hand OA, first carpometacarpal joint; 2010 assessment", "summary_en": "The summary states that ultrasound and laser have not demonstrated benefit in this hand-OA setting.", "summary_fi": "Yhteenveto toteaa, ettei ultraääni- tai laserhoidon hyötyä ole osoitettu tässä käsien nivelrikon käyttötilanteessa.", "locator": "PDF p. 35 / printed p. 34, OA de manos", "evidence_anchor": "Ultrasonido y Laserterapia no han demostrado beneficios", "caveat_en": "Historical evidence assessment, not a universal finding for every later laser device.", "caveat_fi": "Historiallinen näyttöarvio, ei yleinen päätelmä kaikista myöhemmistä laserlaitteista.", "intervention": "Laser therapy; LLLT in cited evidence", "added_in": "expansion_04", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "OA-IMSS-LASER", "document_id": "imss_knee_2014", "specialty": "Musculoskeletal", "condition_en": "Knee osteoarthritis: attributed Australian laser recommendation", "condition_fi": "Polven nivelrikko: siteerattu australialainen lasersuositus", "direction": "mention_only", "strength_as_reported": "D / Shekelle, attributed to RACGP 2009", "evidence_certainty_as_reported": "Ia / Shekelle evidence entries; mixed findings", "scope": "Short-term low-power laser; recommendation attributed to Australian 2009 guidance", "summary_en": "The IMSS guideline reproduces the Australian grade-D short-term statement and summarizes conflicting evidence.", "summary_fi": "IMSS:n ohje toistaa Australian D-luokan lyhytaikaisen kannan ja kuvaa ristiriitaista näyttöä.", "locator": "Printed pp. 29–30, LASER", "evidence_anchor": "Las Guías Australianas recomiendan", "caveat_en": "Grade D is explicitly attributed to the 2009 Australian source. It is not the current RACGP position or independent corroborating trial evidence.", "caveat_fi": "D-luokka on nimenomaisesti vuoden 2009 australialaisen lähteen kanta. Se ei ole nykyinen RACGP-kanta eikä riippumatonta lisätutkimusnäyttöä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-AAPD-CHEMO-HCT", "document_id": "aapd_chemo_2022", "specialty": "Pediatric dentistry", "condition_en": "Oral mucositis prevention in pediatric HCT care", "condition_fi": "Suun mukosiitin ehkäisy lasten kantasolusiirtohoidossa", "direction": "recommended", "strength_as_reported": "Ungraded best practice; cites MASCC/ISOO", "evidence_certainty_as_reported": "", "scope": "HCT conditioning with high-dose chemotherapy, with/without total-body irradiation", "summary_en": "The best-practice document includes PBM among preventive measures and reports MASCC/ISOO support for HCT conditioning.", "summary_fi": "Hyvän käytännön ohje sisällyttää PBM:n ehkäisykeinoihin ja kuvaa MASCC/ISOO:n tuen kantasolusiirron esihoidossa.", "locator": "PDF p. 5 / printed p. 575, Oral mucositis", "evidence_anchor": "prevent OM in patients undergoing HCT conditioning", "caveat_en": "Uses the cited MASCC/ISOO settings; no separate AAPD numeric grade or blanket all-regimen pediatric recommendation is inferred.", "caveat_fi": "Noudattaa siteerattuja MASCC/ISOO-käyttötilanteita; erillistä AAPD:n numeroluokkaa tai kaikkia lasten hoito-ohjelmia kattavaa suositusta ei päätellä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-AAPD-CHEMO-RT", "document_id": "aapd_chemo_2022", "specialty": "Pediatric dentistry", "condition_en": "Oral mucositis prevention in head and neck radiotherapy", "condition_fi": "Suun mukosiitin ehkäisy pään ja kaulan sädehoidossa", "direction": "recommended", "strength_as_reported": "Ungraded best practice; cites MASCC/ISOO", "evidence_certainty_as_reported": "", "scope": "Head and neck radiotherapy; pediatric best-practice context with much adult evidence", "summary_en": "Reports guideline support for preventive PBM in head and neck radiotherapy.", "summary_fi": "Kuvaa suositustuen PBM:n ehkäisevälle käytölle pään ja kaulan sädehoidossa.", "locator": "PDF p. 5 / printed p. 575, Oral mucositis", "evidence_anchor": "patients undergoing radiation treatment for head and neck cancer", "caveat_en": "The text notes limited pediatric data and reliance on adult studies; grade is not transferred from MASCC to a new AAPD-specific grade.", "caveat_fi": "Teksti toteaa lasten aineiston niukkuuden ja tukeutumisen aikuistutkimuksiin. MASCC-luokkaa ei siirretä uudeksi AAPD-kohtaiseksi luokaksi.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OM-AAPD-CHEMO-TREAT", "document_id": "aapd_chemo_2022", "specialty": "Pediatric dentistry", "condition_en": "Established chemotherapy-induced oral mucositis in children", "condition_fi": "Lasten todettu solunsalpaajahoidon aiheuttama suun mukosiitti", "direction": "descriptive_support", "strength_as_reported": "Narrative evidence statement; ungraded", "evidence_certainty_as_reported": "", "scope": "Children with chemotherapy-induced oral mucositis", "summary_en": "The document says PBM can decrease pain, duration and severity of chemotherapy-induced OM in children.", "summary_fi": "Ohje toteaa, että PBM voi vähentää lasten solunsalpaajamukosiitin kipua, kestoa ja vaikeutta.", "locator": "PDF p. 5 / printed p. 575", "evidence_anchor": "PBM can decrease pain and the duration and severity", "caveat_en": "Narrative pediatric treatment evidence, distinct from formal prevention recommendations and from a validated universal protocol.", "caveat_fi": "Kuvaileva lasten hoitonäyttö, erillään muodollisista ehkäisysuosituksista ja yleisesti validoidusta protokollasta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "CMP-SOUTHAFRICA", "document_id": "southafrica_cmp_2023", "specialty": "Pain / primary care", "condition_en": "Chronic musculoskeletal pain: local applicability of LLLT", "condition_fi": "Krooninen tuki- ja liikuntaelinkipu: LLLT:n paikallinen soveltuvuus", "direction": "mention_only", "strength_as_reported": "Local applicability/feasibility not endorsed in initial Delphi round", "evidence_certainty_as_reported": "", "scope": "South African primary health care; implementation context", "summary_en": "LLLT was the only nonpharmacological intervention with uncertain local applicability and feasibility.", "summary_fi": "LLLT oli ainoa lääkkeetön hoito, jonka paikallinen soveltuvuus ja toteutettavuus jäivät epävarmoiksi.", "locator": "Consensus findings before Table 5", "evidence_anchor": "Low-level laser therapy (LLLT) was the only non-pharmacological intervention", "caveat_en": "This concerns local implementation and resources, not a determination of clinical ineffectiveness or a standalone formal efficacy grade.", "caveat_fi": "Tämä koskee paikallista toteutusta ja resursseja, ei kliinisen tehottomuuden osoittamista tai muodollista erillistä teholuokitusta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "OA-SINGAPORE-2026", "document_id": "singapore_knee_2026", "specialty": "Musculoskeletal / primary care", "condition_en": "Knee osteoarthritis: electrotherapy comparison", "condition_fi": "Polven nivelrikko: fysikaalisten hoitojen vertailumaininta", "direction": "mention_only", "strength_as_reported": "No PBM-only graded recommendation", "evidence_certainty_as_reported": "", "scope": "Electrotherapy group including unspecified laser; compared with exercise/conventional therapies", "summary_en": "The guideline cautions that a group including laser may be less effective than conventional therapies such as exercise for pain and function.", "summary_fi": "Ohje huomauttaa, että laserin sisältävä hoitoryhmä saattaa lievittää kipua ja parantaa toimintaa tavanomaisia hoitoja, kuten liikuntaa, heikommin.", "locator": "After Recommendation 6; Notepad: Other complementary and alternative treatments", "evidence_anchor": "laser therapy may be less effective than conventional therapies like exercise", "caveat_en": "Grouped, cautious comparison; not a verified laser-only recommendation against or a finding that every PBM protocol lacks benefit.", "caveat_fi": "Ryhmää koskeva varovainen vertailu, ei vahvistettu laserin erillinen kielteinen suositus eikä päätelmä jokaisen PBM-protokollan hyödyttömyydestä.", "intervention": "Laser therapy; type unspecified, within electrotherapy group", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LYMPH-FRAMEWORK-2006", "document_id": "lympho_framework_2006", "specialty": "Lymphology", "condition_en": "Lymphedema, particularly the upper limb", "condition_fi": "Lymfaturvotus, erityisesti yläraajassa", "direction": "descriptive_support", "strength_as_reported": "No formal laser-specific grade", "evidence_certainty_as_reported": "", "scope": "Lymphedema; limb volume and tissue hardness", "summary_en": "The consensus describes potential LLLT benefit but requests research on treatment benefit and optimal regimens.", "summary_fi": "Konsensus kuvaa LLLT:n mahdollisia hyötyjä mutta pyytää tutkimusta hoidon hyödystä ja optimaalisista protokollista.", "locator": "PDF p. 55 / printed p. 51, Laser therapy", "evidence_anchor": "Low level laser therapy has shown potential", "caveat_en": "Historical 2006 consensus; not a current strong endorsement or proof of a lasting effect.", "caveat_fi": "Historiallinen vuoden 2006 konsensus; ei nykyinen vahva suositus tai osoitus pysyvästä vaikutuksesta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "OM-PTSL-HSCT", "document_id": "ptsl_mucositis_2025", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention in HSCT", "condition_fi": "Suun mukosiitin ehkäisy kantasolusiirrossa", "direction": "recommended", "strength_as_reported": "Society clinical recommendation; no separate numeric strength verified", "evidence_certainty_as_reported": "", "scope": "High-risk oncologic treatment including HSCT; preventive PBM", "summary_en": "Recommends PBM as standard supportive care for high-risk therapies including HSCT, with prevention prioritized.", "summary_fi": "Suosittaa PBM:ää tavanomaiseksi tukihoidon osaksi korkean riskin hoidoissa, kuten kantasolusiirrossa, ja painottaa ehkäisyä.", "locator": "Clinical implications / Key clinical recommendations", "evidence_anchor": "PBMT should be incorporated as standard supportive care", "caveat_en": "Society recommendations built on an umbrella review; not independent patient evidence from MASCC/WALT. Specific eligibility and protocols remain important.", "caveat_fi": "Järjestön suositukset perustuvat katsausten katsaukseen; eivät ole MASCC/WALT:sta riippumatonta potilasaineistoa. Potilasvalinta ja protokollat ovat olennaisia.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "society_consensus" }, { "id": "OM-PTSL-HNC-CRT", "document_id": "ptsl_mucositis_2025", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention in head/neck chemoradiation", "condition_fi": "Suun mukosiitin ehkäisy pään ja kaulan kemosädehoidossa", "direction": "recommended", "strength_as_reported": "Society clinical recommendation; no separate numeric strength verified", "evidence_certainty_as_reported": "", "scope": "High-risk head and neck chemoradiation; preventive PBM", "summary_en": "Includes head and neck chemoradiation among high-risk settings for standard preventive supportive PBM.", "summary_fi": "Sisällyttää pään ja kaulan kemosädehoidon korkean riskin tilanteisiin, joissa PBM kuuluu ehkäisevään tukihoitoon.", "locator": "Key clinical recommendations", "evidence_anchor": "head and neck chemoradiation", "caveat_en": "The recommendation also calls for coordination with the treating oncologist; it is not an unrestricted device or dose endorsement.", "caveat_fi": "Suositus edellyttää yhteistyötä hoitavan onkologin kanssa; se ei hyväksy rajoituksetta kaikkia laitteita tai annoksia.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "society_consensus" }, { "id": "OM-PTSL-TREAT", "document_id": "ptsl_mucositis_2025", "specialty": "Oncology / oral care", "condition_en": "Treatment of established oral mucositis", "condition_fi": "Todetun suun mukosiitin hoito", "direction": "recommended", "strength_as_reported": "Society clinical recommendation; no separate numeric strength verified", "evidence_certainty_as_reported": "", "scope": "PBM after mucositis onset; pain relief and healing", "summary_en": "The society's clinical recommendations describe therapeutic PBM after onset as providing analgesia and accelerating healing.", "summary_fi": "Järjestön kliiniset suositukset kuvaavat oireiden alettua annetun PBM:n lievittävän kipua ja nopeuttavan paranemista.", "locator": "Key clinical recommendations", "evidence_anchor": "Therapeutic PBMT", "caveat_en": "Treatment evidence and population/protocol variability should be retained; preventive and therapeutic use are distinct.", "caveat_fi": "Hoitonäytön vaihtelu potilasryhmissä ja protokollissa on huomioitava; ehkäisy ja todetun mukosiitin hoito ovat eri käyttötapoja.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "society_consensus" }, { "id": "OM-PTSL-PEDS-PROTOCOL", "document_id": "ptsl_mucositis_2025", "specialty": "Pediatric oncology", "condition_en": "Pediatric oral mucositis: proposed age-adapted protocols", "condition_fi": "Lasten suun mukosiitti: ehdotetut ikään sovitetut protokollat", "direction": "expert_protocol", "strength_as_reported": "Society technical protocol; not a separate graded pediatric efficacy recommendation", "evidence_certainty_as_reported": "", "scope": "Young children unable to tolerate intraoral treatment; extraoral near-infrared alternative discussed", "summary_en": "The paper proposes age-adapted delivery, including extraoral treatment for very young children or those unable to tolerate intraoral application.", "summary_fi": "Julkaisu ehdottaa iän mukaista toteutusta, mukaan lukien suunulkoinen hoito hyvin pienille lapsille tai niille, jotka eivät siedä suunsisäistä käsittelyä.", "locator": "Clinical implications; Table 9", "evidence_anchor": "patients who cannot tolerate intraoral application", "caveat_en": "Protocol advice is distinct from direct trial certainty for every pediatric indication; the authors call for further pediatric harmonization.", "caveat_fi": "Protokollaohje eroaa suorasta tutkimusvarmuudesta jokaisessa lasten käyttöaiheessa; kirjoittajat pyytävät lisää lasten käytäntöjen yhtenäistämistä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "society_consensus" }, { "id": "OM-HTW-LASER-ADOPTION", "document_id": "htw_mucositis_2022", "specialty": "Oncology / health technology guidance", "condition_en": "Oral mucositis: routine laser-PBM adoption", "condition_fi": "Suun mukosiitti: laser-PBM:n rutiinikäyttöönotto", "direction": "against", "strength_as_reported": "Routine adoption cannot be supported; contextual HTA recommendation", "evidence_certainty_as_reported": "", "scope": "Welsh NHS; laser PBM clinical and cost effectiveness", "summary_en": "HTW recognizes clinical laser-PBM benefit but does not support routine adoption because its Welsh NHS analysis finds it not cost effective, mainly due to staffing costs.", "summary_fi": "HTW tunnistaa laser-PBM:n kliinistä hyötyä mutta ei tue rutiinikäyttöönottoa, koska Walesin NHS:n analyysissa se ei ole kustannusvaikuttavaa, pääosin henkilöstökustannusten vuoksi.", "locator": "Final Guidance 044, PDF pp. 1–3", "evidence_anchor": "routine adoption of laser photobiomodulation cannot be supported", "caveat_en": "A cost/implementation decision is not a claim of clinical ineffectiveness. The PTSL review's favorable characterization of HTW conflicts with this primary guidance.", "caveat_fi": "Kustannuksiin ja toteutukseen perustuva kanta ei tarkoita kliinistä tehottomuutta. PTSL-katsauksen myönteinen tulkinta HTW:stä on ristiriidassa alkuperäisohjeen kanssa.", "intervention": "Low-level laser PBM", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "procedure_guidance" }, { "id": "OM-HTW-LED", "document_id": "htw_mucositis_2022", "specialty": "Oncology / health technology guidance", "condition_en": "Oral mucositis: LED PBM", "condition_fi": "Suun mukosiitti: LED-PBM", "direction": "insufficient_evidence", "strength_as_reported": "Further research recommended; routine adoption unsupported", "evidence_certainty_as_reported": "Limited clinical evidence", "scope": "LED PBM; prevention/treatment of cancer-treatment-related oral mucositis", "summary_en": "HTW finds LED clinical evidence insufficient and advises further research; it does not transfer laser efficacy data directly to LED.", "summary_fi": "HTW toteaa LED-hoidon kliinisen näytön riittämättömäksi ja suosittaa lisätutkimuksia; laserin tehotietoja ei siirretä suoraan LED:lle.", "locator": "Final Guidance 044, PDF pp. 1–3", "evidence_anchor": "Further research is recommended to establish the clinical effectiveness of LED", "caveat_en": "Laser and LED delivery differ. Economic feasibility alone does not establish clinical efficacy for LED.", "caveat_fi": "Laserin ja LED:n toteutus poikkeavat toisistaan. Pelkkä taloudellinen toteutettavuus ei osoita LED:n kliinistä tehoa.", "intervention": "LED photobiomodulation", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "procedure_guidance" }, { "id": "LIP-RUSSIA-WOUND", "document_id": "russia_lip_2024", "specialty": "Oncology / rehabilitation", "condition_en": "Postoperative wound healing after lip-cancer surgery", "condition_fi": "Huulisyöpäleikkauksen jälkeisen haavan paraneminen", "direction": "recommended", "strength_as_reported": "C (Russian recommendation system)", "evidence_certainty_as_reported": "Level 4 (Russian evidence system)", "scope": "Postoperative rehabilitation after malignant lip neoplasm surgery", "summary_en": "The guideline recommends low-intensity laser to improve postoperative wound healing.", "summary_fi": "Ohje suosittelee matalatehoista laseria leikkauksen jälkeisen haavan paranemisen edistämiseen.", "locator": "Rehabilitation, stage I after surgery; reference 72", "evidence_anchor": "С целью улучшения заживления послеоперационной раны", "caveat_en": "Read from full guideline reproduction. C/4 are the source's grades and are not equated with GRADE. No general claim about oncologic safety is inferred.", "caveat_fi": "Tarkistus täydestä ohjetoistosta. C/4 ovat lähteen omat luokat, joita ei rinnasteta GRADEen. Yleistä päätelmää syöpäturvallisuudesta ei tehdä.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_guideline_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LIP-RUSSIA-TRISMUS", "document_id": "russia_lip_2024", "specialty": "Oncology / rehabilitation", "condition_en": "Trismus after treatment of lip malignancy", "condition_fi": "Huulisyövän hoitoihin liittyvä suun avausrajoitus", "direction": "recommended", "strength_as_reported": "B (Russian recommendation system)", "evidence_certainty_as_reported": "Level 2 (Russian evidence system)", "scope": "Masticatory muscles and temporomandibular joint; correction of trismus", "summary_en": "Recommends low-intensity laser over masticatory musculature and TMJ to address trismus.", "summary_fi": "Suosittelee matalatehoista laseria puremalihasten ja leukanivelen alueelle suun avausrajoituksen korjaamiseksi.", "locator": "Rehabilitation after surgery / stage III; reference 79", "evidence_anchor": "на область жевательной мускулатуры и височно-нижнечелюстной сустав", "caveat_en": "Russian source grading; the recommendation is restricted to its cancer-rehabilitation context.", "caveat_fi": "Lähteen venäläinen luokitus; suositus koskee rajattua syöpäkuntoutuksen tilannetta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_guideline_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LIP-RUSSIA-RD-PREV", "document_id": "russia_lip_2024", "specialty": "Oncology / dermatology", "condition_en": "Radiation dermatitis prevention in lip-cancer treatment", "condition_fi": "Sädeihottuman ehkäisy huulisyövän hoidossa", "direction": "recommended", "strength_as_reported": "B (Russian recommendation system)", "evidence_certainty_as_reported": "Level 2 (Russian evidence system)", "scope": "Throughout RT; prevention of dermatitis above grade 2", "summary_en": "Recommends low-intensity laser throughout RT to prevent radiation dermatitis greater than grade 2.", "summary_fi": "Suosittelee matalatehoista laseria koko sädehoidon ajan yli 2-asteisen sädeihottuman ehkäisyyn.", "locator": "Rehabilitation during RT; reference 99", "evidence_anchor": "профилактики развития радиоиндуцированного дерматита более 2 степени", "caveat_en": "Do not generalize the source's population or grade to every irradiated cancer site.", "caveat_fi": "Lähteen potilasryhmää tai luokitusta ei yleistetä kaikkiin sädehoidettaviin syöpäalueisiin.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_guideline_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LIP-RUSSIA-OM-PREV", "document_id": "russia_lip_2024", "specialty": "Oncology / oral care", "condition_en": "Oral mucositis prevention during RT/CRT for lip cancer", "condition_fi": "Suun mukosiitin ehkäisy huulisyövän säde- tai kemosädehoidossa", "direction": "recommended", "strength_as_reported": "C (Russian recommendation system)", "evidence_certainty_as_reported": "Level 5 (Russian evidence system)", "scope": "Oral-cavity LLLT throughout RT or chemoradiotherapy", "summary_en": "Recommends oral low-intensity laser for mucositis prevention throughout RT/CRT.", "summary_fi": "Suosittelee suun alueen matalatehoista laseria mukosiitin ehkäisyyn koko säde- tai kemosädehoidon ajan.", "locator": "Rehabilitation during RT; reference 100", "evidence_anchor": "на полость рта для профилактики мукозита полости рта", "caveat_en": "Retains C/5 exactly as reported; does not substitute MASCC/ISOO's different grades.", "caveat_fi": "Säilyttää lähteen C/5-luokan; sitä ei korvata MASCC/ISOO:n eri luokituksella.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_guideline_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LIP-RUSSIA-DYSPHAGIA", "document_id": "russia_lip_2024", "specialty": "Oncology / rehabilitation", "condition_en": "Acute dysphagia prevention during lip-cancer RT", "condition_fi": "Akuutin nielemisvaikeuden ehkäisy huulisyövän sädehoidossa", "direction": "recommended", "strength_as_reported": "C (Russian recommendation system)", "evidence_certainty_as_reported": "Level 5 (Russian evidence system)", "scope": "RT; acute dysphagia, parenteral nutrition and opioid-use frequency", "summary_en": "Recommends low-intensity laser to prevent acute dysphagia and reduce parenteral-nutrition needs and opioid use during RT.", "summary_fi": "Suosittelee matalatehoista laseria akuutin nielemisvaikeuden ehkäisyyn sekä parenteraalisen ravitsemuksen ja opioidikäytön tarpeen vähentämiseen sädehoidon aikana.", "locator": "Rehabilitation during RT; reference 101", "evidence_anchor": "для профилактики острой дисфагии", "caveat_en": "These are outcomes listed by this guideline, not a quantified independent efficacy finding or a general dysphagia recommendation.", "caveat_fi": "Nämä ovat ohjeessa luetellut tavoitteet, eivät määrällinen riippumaton tehotulos tai yleinen nielemisvaikeuden hoitosuositus.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text_guideline_reproduction", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-RACGP-2009", "document_id": "racgp_oa_2009", "specialty": "Musculoskeletal / primary care", "condition_en": "Knee osteoarthritis: historical short-term laser option", "condition_fi": "Polven nivelrikko: historiallinen lyhytaikainen laservaihtoehto", "direction": "may_consider", "strength_as_reported": "D; weak evidence", "evidence_certainty_as_reported": "", "scope": "Short-term treatment of knee OA in the 2009 edition", "summary_en": "The 2009 guideline weakly supports GPs recommending short-term LLLT for knee OA.", "summary_fi": "Vuoden 2009 ohje tukee heikosti yleislääkärin suosittamaa lyhytaikaista LLLT:tä polven nivelrikkoon.", "locator": "Recommendation 18; PDF pp. 19 and 34 / printed pp. 17 and 32", "evidence_anchor": "weak evidence to support GPs recommending low level laser therapy", "caveat_en": "Superseded by RACGP 2018, which recommends against LLLT and is already included. Historical support is not current endorsement.", "caveat_fi": "Korvattu vuoden 2018 ohjeella, joka suosittelee LLLT:tä vastaan ja on jo koonnissa. Historiallinen tuki ei ole nykyinen kanta.", "intervention": "PBM / low-level laser therapy", "added_in": "expansion_04", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "LBP-ECUADOR-2016", "document_id": "ecuador_lbp_2016", "specialty": "Musculoskeletal / primary care", "condition_en": "Subacute or chronic low back pain: laser mention", "condition_fi": "Subakuutti tai krooninen alaselkäkipu: lasermaininta", "direction": "mention_only", "strength_as_reported": "Specialist discretion; grouped evidence statement", "evidence_certainty_as_reported": "Low evidence in narrative; E-1a source notation", "scope": "Electrotherapy group including laser; specialist discretion", "summary_en": "The guideline describes low evidence for electrotherapies including laser and leaves their use to specialist judgment.", "summary_fi": "Ohje kuvaa laserin sisältävien fysikaalisten hoitojen näytön vähäiseksi ja jättää käytön erikoislääkärin harkintaan.", "locator": "PDF p. 28 / printed p. 26, Electroterapia", "evidence_anchor": "quedando a criterio del especialista", "caveat_en": "Laser class is unspecified and the glossary describes heat generation. A nonthermal PBM-specific positive recommendation is not verified.", "caveat_fi": "Laserluokkaa ei eritellä, ja sanasto kuvaa lämmön muodostusta. Ei-lämpövaikutteisen PBM:n myönteistä erillissuositusta ei vahvistettu.", "intervention": "Laser unspecified, within electrotherapy group", "added_in": "expansion_04", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "PRESSURE-RNAO-2016", "document_id": "rnao_pressure_2016", "specialty": "Wound care", "condition_en": "Stalled but healable pressure injuries", "condition_fi": "Hitaasti paranevat mutta paranemiskykyiset painehaavat", "direction": "against", "strength_as_reported": "Not recommended; no laser-specific grade verified", "evidence_certainty_as_reported": "", "scope": "2016 recommendation 3.6; speeding pressure-injury closure", "summary_en": "The historical RNAO recommendation says not to consider laser for speeding closure of stalled but healable pressure injuries.", "summary_fi": "Historiallinen RNAO-suositus kehottaa olemaan käyttämättä laseria hitaasti paranevien mutta paranemiskykyisten painehaavojen sulkeutumisen nopeuttamiseen.", "locator": "2016 recommendation 3.6 reproduced in official 2024 comparison, PDF p. 14", "evidence_anchor": "laser therapy (not recommended)", "caveat_en": "The wording belongs to the superseded 2016 guideline, not the 2024 recommendation column; no current 2024 PBM direction is inferred.", "caveat_fi": "Sanamuoto kuuluu korvattuun vuoden 2016 ohjeeseen, ei taulukon 2024-suositussarakkeeseen. Nykyistä vuoden 2024 PBM-kantaa ei päätellä.", "intervention": "Laser therapy; source class unspecified", "added_in": "expansion_04", "historical": true, "checked_on": "2026-10-16", "verification_depth": "historical_recommendation_in_2024_official_comparison", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "OA-STM-2019", "document_id": "stm_oa_2019", "specialty": "Musculoskeletal", "condition_en": "Knee osteoarthritis", "condition_fi": "Polven nivelrikko", "direction": "may_consider", "strength_as_reported": "Limitedly recommended; qualitative consensus label", "evidence_certainty_as_reported": "", "scope": "Symptomatic knee OA; clinical rationale mainly concerns knee OA", "summary_en": "Labels PBMT/LLLT as limitedly recommended while describing mixed clinical evidence and the need for better trials.", "summary_fi": "Luokittelee PBM:n/LLLT:n rajallisesti suositeltavaksi mutta kuvaa ristiriitaista kliinistä näyttöä ja lisätutkimusten tarvetta.", "locator": "Treatment / PBMT or low-level laser therapy (LLLT)", "evidence_anchor": "PBMT or low-level laser therapy (LLLT) (limitedly recommended)", "caveat_en": "The heading and cautious rationale must be read together. Experimental cartilage findings are not human clinical efficacy or a formal certainty grade.", "caveat_fi": "Myönteinen otsikko ja varovaiset perustelut kuuluvat yhteen. Eläinmallien rustotuloksia ei esitetä kliinisenä ihmistutkimusnäyttönä.", "intervention": "PBMT / LLLT; nonthermal visible and infrared light", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "RD-EVIQ-PREVENT", "document_id": "eviq_rd_2025", "specialty": "Oncology supportive care", "condition_en": "Prevention of radiation-induced dermatitis", "condition_fi": "Sädeihottuman ehkäisy", "direction": "descriptive_support", "strength_as_reported": "Emerging prevention strategy; no separate eviQ PBM grade", "evidence_certainty_as_reported": "", "scope": "Prevention during radiotherapy; evidence discussion includes breast and head/neck studies", "summary_en": "Describes PBMT as an emerging prevention strategy and summarizes evidence of less moderate-to-severe dermatitis and fewer treatment interruptions.", "summary_fi": "Kuvaa PBM:ää kehittyväksi ehkäisykeinoksi ja selostaa näyttöä vaikeampien ihoreaktioiden sekä hoitokeskeytysten vähentymisestä.", "locator": "Management / prevention / Photo-biomodulation (low-level laser) therapy", "evidence_anchor": "as an emerging strategy to prevent higher-grade RID", "caveat_en": "This resource cites other guidelines and a review. It is not an independent PBM-only graded recommendation or support for treating established dermatitis.", "caveat_fi": "Lähde viittaa muihin suosituksiin ja katsaukseen. Tästä ei päätellä uutta erillistä suositusluokkaa tai tukea jo syntyneen sädeihottuman hoitoon.", "intervention": "PBMT / low-level laser therapy", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_statement" }, { "id": "PDN-AAN-2011", "document_id": "aan_pdn_2011", "specialty": "Neurology", "condition_en": "Painful diabetic neuropathy", "condition_fi": "Kivulias diabeettinen neuropatia", "direction": "against", "strength_as_reported": "Level B; should probably not be considered", "evidence_certainty_as_reported": "Single Class I study", "scope": "Pain treatment in diabetic neuropathy; historical guideline", "summary_en": "Advises probably not considering low-intensity laser for painful diabetic neuropathy.", "summary_fi": "Historiallinen ohje suosittaa olemaan käyttämättä matalatehoista laseria kivuliaan diabeettisen neuropatian hoidossa (Level B).", "locator": "Nonpharmacologic treatment / Recommendations, item 2", "evidence_anchor": "low-intensity laser treatment, and Reiki therapy should probably not be considered", "caveat_en": "Retired 2011 guideline. Class I is the source study classification, not a new GRADE rating; the later oral/topical update does not reappraise laser.", "caveat_fi": "Poistettu käytöstä oleva vuoden 2011 ohje. Class I kuvaa tutkimusluokkaa; vuoden 2022 lääkehoitopäivityksestä ei päätellä uutta laserkantaa.", "intervention": "Low-intensity laser treatment", "added_in": "expansion_05", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "AGA-EGYPT-2025", "document_id": "egypt_aga_2025", "specialty": "Dermatology", "condition_en": "Androgenetic alopecia", "condition_fi": "Androgeeninen hiustenlähtö", "direction": "descriptive_support", "strength_as_reported": "Consensus statement 17; 95% agreement", "evidence_certainty_as_reported": "", "scope": "AGA; statement discusses three sessions per week", "summary_en": "The panel agrees that LLLT three times weekly can shift hair measures toward more terminal hair and larger shaft diameter.", "summary_fi": "Paneelin lausuma kuvaa kolmesti viikossa annetun LLLT:n myönteisiä vaikutuksia terminaalihiuksiin ja hiusten paksuuteen.", "locator": "Table 1, statement 17 / Key Area 4: Low-Level Laser Therapy", "evidence_anchor": "Low-level laser therapy three times per week causes a decrease in the number of vellus hairs", "caveat_en": "Agreement percentage is not certainty or a quantitative treatment effect. The wording is a supportive consensus statement, not an independently graded universal prescription.", "caveat_fi": "95 % on paneelin yksimielisyys, ei näytön varmuus tai hoidon tehoprosentti. Lausuma ei määritä kaikkia laitteita koskevaa annostusta.", "intervention": "Low-level laser therapy", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "AGA-CANADA-2025", "document_id": "canada_aga_2025", "specialty": "Dermatology", "condition_en": "Androgenetic alopecia in adults", "condition_fi": "Aikuisten androgeeninen hiustenlähtö", "direction": "may_consider", "strength_as_reported": "Recommended with near consensus; abstract wording", "evidence_certainty_as_reported": "", "scope": "Male and female adults with AGA", "summary_en": "The indexed abstract lists LLLT among interventions recommended with near consensus as part of an AGA regimen.", "summary_fi": "Abstrakti luettelee LLLT:n hoitokokonaisuuden vaihtoehdoksi, jota paneeli kannattaa lähes yksimielisesti.", "locator": "Primary indexed abstract / recommended with near consensus", "evidence_anchor": "Five interventions are recommended with near consensus", "caveat_en": "Full-text vote, protocol, device details and qualifications were inaccessible. Near consensus is preserved and not promoted to unanimous or strong recommendation.", "caveat_fi": "Kokotekstin äänestys-, laite- ja protokollatiedot jäivät varmistamatta. Lähteen lähes yksimielistä kantaa ei muuteta vahvaksi tai yksimieliseksi suositukseksi.", "intervention": "Low level laser therapy", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "abstract", "final_grade_recheck_needed": false, "recommendation_class": "expert_consensus_article" }, { "id": "VULVODYNIA-EUROPE-2021", "document_id": "iusti_vulval_2021", "specialty": "Gynecology / sexual health", "condition_en": "Vulvodynia / provoked vestibulodynia", "condition_fi": "Vulvodynia / provosoitu vestibulodynia", "direction": "insufficient_evidence", "strength_as_reported": "No separate LLLT grade in the statement", "evidence_certainty_as_reported": "", "scope": "Vulvodynia treatment", "summary_en": "States that efficacy of low-level laser for vulvodynia has not been demonstrated.", "summary_fi": "Ohje toteaa, ettei matalatehoisen laserin tehosta vulvodynian hoidossa ole osoitusta.", "locator": "Vulvodynia / physical therapies; PDF page 14", "evidence_anchor": "low-level laser therapy and radiofrequency for treating vulvodynia", "caveat_en": "LLLT is explicitly named separately from fractional CO2 treatment. No laser-specific GRADE grade or proof of ineffectiveness for every later protocol is inferred.", "caveat_fi": "LLLT mainitaan erillään fraktionaalisesta CO2-hoidosta. Lauseesta ei päätellä erillistä GRADE-luokkaa tai kaikkien myöhempien protokollien tehottomuutta.", "intervention": "Low-level laser therapy; separate from fractional CO2 laser", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACNE-EUROGUIDERM-COMEDONAL", "document_id": "euroguiderm_acne_2025", "specialty": "Dermatology", "condition_en": "Comedonal acne", "condition_fi": "Komedoakne", "direction": "insufficient_evidence", "strength_as_reported": "Open recommendation", "evidence_certainty_as_reported": "", "scope": "Induction treatment of comedonal acne", "summary_en": "Places visible light and laser among interventions for which no recommendation for or against can be made.", "summary_fi": "Näkyvä valo ja laser kuuluvat hoitoihin, joiden puolesta tai vastaan ei voida antaa suositusta.", "locator": "Section 6.1.1 graphical table, printed p. 27 / PDF p. 33; rationale p. 31", "evidence_anchor": "no clear recommendations could be drawn", "caveat_en": "The open category means no recommendation for or against. The separate blue-light recommendation does not support red/NIR PBM, and IPL/PDT/ablative laser are different interventions.", "caveat_fi": "Avoin kanta tarkoittaa, ettei voida suositella puolesta eikä vastaan. Sinivalon eri luokkaa ei siirretä puna-/lähi-infrapuna-PBM:lle; IPL, PDT ja ablatiivinen laser ovat eri hoitoja.", "intervention": "Visible light / laser; not a PBM-only device class", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACNE-EUROGUIDERM-MILD", "document_id": "euroguiderm_acne_2025", "specialty": "Dermatology", "condition_en": "Mild to moderate papulopustular acne", "condition_fi": "Lievä tai keskivaikea papulopustulaarinen akne", "direction": "insufficient_evidence", "strength_as_reported": "Open recommendation", "evidence_certainty_as_reported": "", "scope": "Induction therapy; severity-specific recommendation table", "summary_en": "The recommendation table places red light in the open category; available evidence does not permit a recommendation for or against.", "summary_fi": "Suositustaulukko sijoittaa punavalon avoimeen luokkaan: näyttö ei riitä kannanottoon puolesta tai vastaan.", "locator": "6.2.1 graphical table, printed p. 32 / PDF p. 38; rationale printed pp. 35–38", "evidence_anchor": "insufficient evidence to recommend the treatment of papulopustular acne with", "caveat_en": "The open category means no recommendation for or against. The separate blue-light recommendation does not support red/NIR PBM, and IPL/PDT/ablative laser are different interventions.", "caveat_fi": "Avoin kanta tarkoittaa, ettei voida suositella puolesta eikä vastaan. Sinivalon eri luokkaa ei siirretä puna-/lähi-infrapuna-PBM:lle; IPL, PDT ja ablatiivinen laser ovat eri hoitoja.", "intervention": "Red light; separately listed from IPL, laser and PDT", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACNE-EUROGUIDERM-SEVERE", "document_id": "euroguiderm_acne_2025", "specialty": "Dermatology", "condition_en": "Severe papulopustular / moderate nodular acne", "condition_fi": "Vaikea papulopustulaarinen tai keskivaikea nodulaarinen akne", "direction": "insufficient_evidence", "strength_as_reported": "Open recommendation", "evidence_certainty_as_reported": "", "scope": "Induction therapy; severity-specific recommendation table", "summary_en": "The recommendation table places red light in the open category; available evidence does not permit a recommendation for or against.", "summary_fi": "Suositustaulukko sijoittaa punavalon avoimeen luokkaan: näyttö ei riitä kannanottoon puolesta tai vastaan.", "locator": "6.2.2 graphical table, printed p. 33 / PDF p. 39; rationale printed pp. 35–38", "evidence_anchor": "insufficient evidence to recommend the treatment of papulopustular acne with", "caveat_en": "The open category means no recommendation for or against. The separate blue-light recommendation does not support red/NIR PBM, and IPL/PDT/ablative laser are different interventions.", "caveat_fi": "Avoin kanta tarkoittaa, ettei voida suositella puolesta eikä vastaan. Sinivalon eri luokkaa ei siirretä puna-/lähi-infrapuna-PBM:lle; IPL, PDT ja ablatiivinen laser ovat eri hoitoja.", "intervention": "Red light; separately listed from IPL, laser and PDT", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACNE-EUROGUIDERM-MAINTENANCE", "document_id": "euroguiderm_acne_2025", "specialty": "Dermatology", "condition_en": "Acne maintenance therapy", "condition_fi": "Aknen ylläpitohoito", "direction": "insufficient_evidence", "strength_as_reported": "Open recommendation", "evidence_certainty_as_reported": "", "scope": "Maintenance therapy across stated acne severities", "summary_en": "Cannot recommend for or against red-light maintenance treatment because of insufficient evidence.", "summary_fi": "Näyttö ei riitä suosittelemaan aknen punavaloylläpitohoidon puolesta tai vastaan.", "locator": "Section 7.1, printed p. 66 / PDF p. 72", "evidence_anchor": "maintenance treatment with red light, blue light, IPL, Laser, PDT or oral zinc", "caveat_en": "The open category means no recommendation for or against. The separate blue-light recommendation does not support red/NIR PBM, and IPL/PDT/ablative laser are different interventions.", "caveat_fi": "Avoin kanta tarkoittaa, ettei voida suositella puolesta eikä vastaan. Sinivalon eri luokkaa ei siirretä puna-/lähi-infrapuna-PBM:lle; IPL, PDT ja ablatiivinen laser ovat eri hoitoja.", "intervention": "Red light; within an open recommendation listing several separate modalities", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "PAIN-JAPAN-PHYSICAL", "document_id": "japan_chronicpain_2021", "specialty": "Pain medicine", "condition_en": "Chronic musculoskeletal pain: physical modalities", "condition_fi": "Pitkäaikainen tuki- ja liikuntaelinkipu: fysikaaliset hoidot", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation; 89.5% agreement; grouped modalities", "evidence_certainty_as_reported": "C (low); grouped physical modalities", "scope": "Adults with chronic low-back pain, chronic neck pain or knee OA in CQ G-3", "summary_en": "Gives no recommendation for a physical-modalities group including LLLT, despite some short-term pain/function effects versus sham or no treatment.", "summary_fi": "Ei anna suositusta fysikaalisten hoitojen ryhmälle, johon LLLT sisältyy, vaikka teksti kuvaa joitakin lyhytaikaisia kipu- ja toimintakykyhyötyjä.", "locator": "CQ G-3, printed pp. 134–135 / PDF pp. 136–137", "evidence_anchor": "推奨度：推奨なし［合意率89.5％］", "caveat_en": "C/low is the grouped appraisal, not an isolated laser grade. Narrative favors any use as an exercise adjunct; medium/long-term effects remain unknown.", "caveat_fi": "C/matala koskee hoitoryhmää, ei vain laseria. Mahdollinen käyttö kuvataan liikuntaharjoittelun lisänä; pidempiaikainen hyöty jää epäselväksi.", "intervention": "LLLT within a group of physical modalities", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "NECK-JAPAN-KATAKORI", "document_id": "japan_chronicpain_2021", "specialty": "Pain medicine", "condition_en": "Chronic neck/shoulder stiffness (katakori)", "condition_fi": "Niska-hartiaseudun jäykkyys ja kipu (katakori)", "direction": "descriptive_support", "strength_as_reported": "Narrative answer; no separate LLLT recommendation grade", "evidence_certainty_as_reported": "Low certainty in explanatory text; not separately graded", "scope": "Katakori; non-drug and non-invasive interventions", "summary_en": "Describes short-term pain and physical-function benefit with low-level laser; medium/long-term benefit is unclear.", "summary_fi": "Kuvaa matalatehoisella laserilla lyhytaikaista kipu- ja toimintakykyhyötyä; keskipitkä ja pitkä vaikutus jäävät epäselviksi.", "locator": "CQ L-5, printed p. 191 / PDF p. 193", "evidence_anchor": "物理療法（低出力レーザー）", "caveat_en": "Katakori is not frozen shoulder or rotator cuff disease. A narrative benefit statement is not a strong formal recommendation.", "caveat_fi": "Katakori ei tarkoita jäätynyttä olkapäätä tai kiertäjäkalvosinvaivaa. Kuvailevaa hyötyarviota ei muuteta vahvaksi suositukseksi.", "intervention": "Low-level laser therapy", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "TN-JAPAN-2021", "document_id": "japan_chronicpain_2021", "specialty": "Oral medicine / neurology", "condition_en": "Trigeminal neuralgia", "condition_fi": "Kolmoishermosärky", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation; 85.0% agreement", "evidence_certainty_as_reported": "C (low)", "scope": "Non-invasive non-drug treatment of trigeminal neuralgia", "summary_en": "Gives no recommendation for LLLT in trigeminal neuralgia; evidence certainty is low.", "summary_fi": "Ei anna LLLT-suositusta kolmoishermosärkyyn; näytön varmuus on matala.", "locator": "CQ M-2-4, printed p. 201 / PDF p. 203, item 2a", "evidence_anchor": "推奨度：推奨なし ［合意率85.0％］", "caveat_en": "The 85% figure is agreement on no recommendation, not a response rate. Grades for decompression, radiosurgery or radiofrequency do not apply to LLLT.", "caveat_fi": "85 % on yksimielisyys suosituksen puuttumisesta, ei hoitovaste. Leikkaus- tai radiotaajuushoitojen luokkia ei siirretä LLLT:lle.", "intervention": "Low-level laser therapy", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "BMS-JAPAN-2021", "document_id": "japan_chronicpain_2021", "specialty": "Oral medicine / neurology", "condition_en": "Burning mouth syndrome", "condition_fi": "Suupolteoireyhtymä", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation; 100% agreement", "evidence_certainty_as_reported": "D (very low)", "scope": "Non-drug treatment of burning mouth syndrome", "summary_en": "Gives no recommendation for LLLT; few studies and very-low-certainty evidence do not establish sufficient benefit.", "summary_fi": "Ei anna LLLT-suositusta suupolteoireyhtymään; vähäiset tutkimukset ja erittäin epävarma näyttö eivät osoita riittävää hyötyä.", "locator": "CQ M-3-4, printed pp. 205–206 / PDF pp. 207–208, item 2", "evidence_anchor": "エビデンス総体の統括：D（非常に低い）", "caveat_en": "The weak recommendation for cognitive behavioral therapy is separate and must not be transferred to LLLT.", "caveat_fi": "Samassa kohdassa annettua kognitiivisen terapian heikkoa suositusta ei siirretä LLLT:lle.", "intervention": "Low-level laser therapy", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "PIDAP-JAPAN-2021", "document_id": "japan_chronicpain_2021", "specialty": "Oral medicine / neurology", "condition_en": "Persistent idiopathic dentoalveolar pain (PIDAP)", "condition_fi": "Pitkittynyt idiopaattinen dentoalveolaarinen kipu (PIDAP)", "direction": "insufficient_evidence", "strength_as_reported": "Narrative answer; no separate LLLT grade", "evidence_certainty_as_reported": "", "scope": "PIDAP as defined in ICOP 2020", "summary_en": "Mentions LLLT research in primary chronic orofacial pain but identifies no established PIDAP-specific treatment or targeted efficacy studies.", "summary_fi": "Mainitsee LLLT:n kroonisen suun ja kasvojen kivun tutkimuksissa mutta toteaa PIDAP-kohtaisen hoitonäytön ja vakiintuneen hoidon puuttuvan.", "locator": "CQ M-4-4, printed p. 209 / PDF p. 211", "evidence_anchor": "PIDAP に特定した治療効果の研究は未だ報告がない", "caveat_en": "Effects in broader or older atypical facial-pain populations cannot automatically be assigned to ICOP-defined PIDAP.", "caveat_fi": "Laajempien tai vanhoilla määritelmillä tutkittujen kasvokipuryhmien tuloksia ei siirretä automaattisesti ICOP-määritelmän PIDAP:hen.", "intervention": "Low-level laser therapy", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "PDN-JAPAN-2021", "document_id": "japan_chronicpain_2021", "specialty": "Neurology", "condition_en": "Painful diabetic peripheral neuropathy", "condition_fi": "Kivulias diabeettinen ääreishermoston neuropatia", "direction": "insufficient_evidence", "strength_as_reported": "No recommendation; 100% agreement", "evidence_certainty_as_reported": "C (low)", "scope": "Adjunctive analgesia in PDPN", "summary_en": "Formally gives no recommendation because evidence is low quality, while its narrative describes possible temporary adjunctive analgesia.", "summary_fi": "Muodollinen kanta on ei suositusta matalan näytön vuoksi; perusteluteksti kuvaa silti mahdollista tilapäistä lisäkivunlievitystä.", "locator": "CQ P-6-3, printed pp. 256–257 / PDF pp. 258–259", "evidence_anchor": "PDPN の痛みに対する補助的鎮痛法として有用である", "caveat_en": "The narrative and formal no-recommendation rating are both retained. Neither possible adjunctive benefit nor lack of serious events establishes a strong efficacy or universal safety recommendation.", "caveat_fi": "Mahdollinen lisähyöty ja muodollinen suosituksen puuttuminen säilytetään rinnakkain. Haittahavaintojen niukkuudesta ei päätellä yleistä turvallisuutta.", "intervention": "Low-level laser therapy", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-ALBERTA-2011-ACUTE", "document_id": "alberta_lbp_2011", "specialty": "Musculoskeletal", "condition_en": "Acute/subacute low back pain", "condition_fi": "Akuutti tai subakuutti alaselkäkipu", "direction": "insufficient_evidence", "strength_as_reported": "Insufficient evidence for or against", "evidence_certainty_as_reported": "RCT (G1) + SR (IHE database); evidence-source labels", "scope": "Acute/subacute nonspecific low back pain in primary care", "summary_en": "Lists LLLT among interventions with insufficient evidence to recommend for or against.", "summary_fi": "Luettelee LLLT:n hoitoihin, joiden puolesta tai vastaan suosittelemiseen näyttö ei riitä.", "locator": "Additional options / insufficient-evidence list, PDF and printed p. 14", "evidence_anchor": "low-level laser therapy*", "caveat_en": "Historical second edition, superseded by the third edition. The SR/RCT/EO entries identify source types and are not certainty grades.", "caveat_fi": "Historiallinen, kolmannella painoksella korvattu toinen painos. SR-, RCT- ja EO-merkinnät kuvaavat lähteiden tyyppiä, eivät näytön varmuusluokkaa.", "intervention": "Low-level laser therapy; glossary defines 632–904 nm", "added_in": "expansion_05", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "LBP-ALBERTA-2011-CHRONIC", "document_id": "alberta_lbp_2011", "specialty": "Musculoskeletal", "condition_en": "Chronic low back pain", "condition_fi": "Pitkäaikainen alaselkäkipu", "direction": "insufficient_evidence", "strength_as_reported": "Insufficient evidence for or against", "evidence_certainty_as_reported": "EO (GDG); evidence-source label", "scope": "Chronic nonspecific low back pain in primary care", "summary_en": "Lists LLLT among interventions with insufficient evidence to recommend for or against.", "summary_fi": "Luettelee LLLT:n hoitoihin, joiden puolesta tai vastaan suosittelemiseen näyttö ei riitä.", "locator": "Additional options / insufficient-evidence list, PDF and printed p. 21", "evidence_anchor": "low-level laser therapy*", "caveat_en": "Historical second edition, superseded by the third edition. The SR/RCT/EO entries identify source types and are not certainty grades.", "caveat_fi": "Historiallinen, kolmannella painoksella korvattu toinen painos. SR-, RCT- ja EO-merkinnät kuvaavat lähteiden tyyppiä, eivät näytön varmuusluokkaa.", "intervention": "Low-level laser therapy; glossary defines 632–904 nm", "added_in": "expansion_05", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "LBP-ALBERTA-2015-ACUTE", "document_id": "alberta_lbp_2015", "specialty": "Musculoskeletal", "condition_en": "Acute/subacute low back pain", "condition_fi": "Akuutti tai subakuutti alaselkäkipu", "direction": "insufficient_evidence", "strength_as_reported": "Insufficient evidence for or against", "evidence_certainty_as_reported": "RCT (G1) + SR (IHE database); evidence-source labels", "scope": "Acute/subacute nonspecific low back pain in primary care", "summary_en": "Lists LLLT among interventions with insufficient evidence to recommend for or against.", "summary_fi": "Luettelee LLLT:n hoitoihin, joiden puolesta tai vastaan suosittelemiseen näyttö ei riitä.", "locator": "Additional options / insufficient-evidence list, PDF and printed p. 11", "evidence_anchor": "Low-level laser therapy", "caveat_en": "Third edition 2015, minor revision 2017. The SR/RCT/EO entries identify source types and are not certainty grades.", "caveat_fi": "Kolmas painos 2015, pieni päivitys 2017. SR-, RCT- ja EO-merkinnät kuvaavat lähteiden tyyppiä, eivät näytön varmuusluokkaa.", "intervention": "Low-level laser therapy; glossary defines 632–904 nm", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LBP-ALBERTA-2015-CHRONIC", "document_id": "alberta_lbp_2015", "specialty": "Musculoskeletal", "condition_en": "Chronic low back pain", "condition_fi": "Pitkäaikainen alaselkäkipu", "direction": "insufficient_evidence", "strength_as_reported": "Insufficient evidence for or against", "evidence_certainty_as_reported": "SR (IHE Database); evidence-source label", "scope": "Chronic nonspecific low back pain in primary care", "summary_en": "Lists LLLT among interventions with insufficient evidence to recommend for or against.", "summary_fi": "Luettelee LLLT:n hoitoihin, joiden puolesta tai vastaan suosittelemiseen näyttö ei riitä.", "locator": "Additional options / insufficient-evidence list, PDF and printed p. 20", "evidence_anchor": "Low-level laser therapy", "caveat_en": "Third edition 2015, minor revision 2017. The SR/RCT/EO entries identify source types and are not certainty grades.", "caveat_fi": "Kolmas painos 2015, pieni päivitys 2017. SR-, RCT- ja EO-merkinnät kuvaavat lähteiden tyyppiä, eivät näytön varmuusluokkaa.", "intervention": "Low-level laser therapy; glossary defines 632–904 nm", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACHILLES-DUTCH-2021", "document_id": "dutch_achilles_2021", "specialty": "Musculoskeletal", "condition_en": "Achilles tendinopathy after initial rehabilitation", "condition_fi": "Akillesjänteen tendinopatia alkukuntoutuksen jälkeen", "direction": "may_consider", "strength_as_reported": "Can be considered; grouped additional modalities", "evidence_certainty_as_reported": "", "scope": "Persistent symptoms after 3 months of education, structured exercise and loading advice; continue exercise", "summary_en": "Includes laser/light among additional options that may be discussed after an inadequate response, with explicit uncertainty about added benefit.", "summary_fi": "Sisällyttää laser-/valohoidon lisävaihtoehtoihin, joista voidaan keskustella riittämättömän alkukuntoutusvasteen jälkeen; lisähyöty on epävarma.", "locator": "Module 4 / Submodule 4.3: non-surgical treatment options / Recommendations", "evidence_anchor": "laser therapy and light therapy", "caveat_en": "This is a shared-decision option within a mixed list, not proof that PBM adds benefit or a replacement for continued exercise. The device class is unspecified.", "caveat_fi": "Kyse on yhteisen harkinnan vaihtoehdosta sekaryhmässä, ei osoituksesta PBM:n lisähyödystä tai harjoittelun korvaamisesta. Laiteluokkaa ei eritellä.", "intervention": "Laser therapy and light therapy; class unspecified", "added_in": "expansion_05", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "OA-GERMANY-2024", "document_id": "german_knee_2024", "specialty": "Musculoskeletal", "condition_en": "Knee osteoarthritis", "condition_fi": "Polven nivelrikko", "direction": "against", "strength_as_reported": "Strong against (⇓⇓); grouped recommendation; 89% consensus", "evidence_certainty_as_reported": "", "scope": "People with knee OA; group of electrotherapeutic interventions", "summary_en": "Strongly advises against a group including laser because evidence of benefit is insufficient; the recommendation adopts NICE NG226.", "summary_fi": "Suosittelee vahvasti olemaan käyttämättä laserin sisältävää hoitoryhmää, koska hyötynäyttö ei riitä. Kanta on sovitettu NICE NG226 -ohjeesta.", "locator": "Recommendation 39, printed p. 22 and pp. 155–158", "evidence_anchor": "Lasertherapie", "caveat_en": "The 89% figure is panel agreement. Very-low-certainty excerpts displayed for NMES/ultrasound are not a laser-only grade. Do not count adoption as an independent evidence vote.", "caveat_fi": "89 % on paneelin yksimielisyys. Taulukon NMES-/ultraääniluokkia ei siirretä laserin näytön varmuudeksi; sovitus ei ole riippumaton lisätutkimustulos.", "intervention": "Lasertherapie; device class unspecified, within grouped electrotherapies", "added_in": "expansion_06", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "FIBRO-GERMANY-2017", "document_id": "german_fibro_2017", "specialty": "Pain medicine", "condition_en": "Fibromyalgia syndrome", "condition_fi": "Fibromyalgia", "direction": "against", "strength_as_reported": "Negative recommendation; strong consensus", "evidence_certainty_as_reported": "EL3a (source system)", "scope": "Fibromyalgia; physical modalities; historical guideline", "summary_en": "The 2017 guideline says laser therapy should not be recommended, retaining the earlier negative position.", "summary_fi": "Vuoden 2017 ohje toteaa, ettei laserhoitoa pidä suositella fibromyalgiaan, ja säilyttää aiemman kielteisen kannan.", "locator": "Physical modalities / Lasertherapie, printed and PDF p. 78", "evidence_anchor": "Lasertherapie sollte nicht empfohlen werden.", "caveat_en": "Expired historical edition. The strong consensus qualifier describes agreement, while EL3a is the source evidence category; neither is converted to GRADE.", "caveat_fi": "Vanhentunut historiallinen versio. Vahva konsensus kuvaa yksimielisyyttä ja EL3a lähteen omaa näyttöluokkaa; niitä ei muuteta GRADE-luokiksi.", "intervention": "Lasertherapie; physical-modality context", "added_in": "expansion_06", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "LBP-CDC-2022", "document_id": "cdc_opioid_2022", "specialty": "Musculoskeletal", "condition_en": "Chronic low back pain: nonopioid treatment options", "condition_fi": "Pitkäaikainen alaselkäkipu: lääkkeettömät hoitovaihtoehdot", "direction": "recommended", "strength_as_reported": "Named implementation option; no separate LLLT grade", "evidence_certainty_as_reported": "", "scope": "Adults with chronic low-back pain; individualized choice of appropriate noninvasive nonpharmacologic therapy", "summary_en": "Names LLLT among appropriate noninvasive options clinicians should recommend for chronic low-back pain under the broader nonopioid-care recommendation.", "summary_fi": "Nimeää LLLT:n pitkäaikaisen alaselkäkivun lääkkeettömiin vaihtoehtoihin, joita lääkäri voi suositella potilaskohtaisesti laajemman opioideja korvaavan hoidon osana.", "locator": "Recommendation 2 / Implementation Considerations / condition-specific nonpharmacologic approaches", "evidence_anchor": "psychological therapy, spinal manipulation, low-level laser therapy, massage", "caveat_en": "Category A and evidence type 2 belong to the broad Recommendation 2, not an isolated PBM efficacy rating. This passage concerns low-back pain, not every chronic pain condition.", "caveat_fi": "Suosituksen A-luokka ja näyttötyyppi 2 koskevat laajaa suositusta 2, eivät PBM:n erillistä teholuokitusta. Lasermainintaa ei yleistetä kaikkiin kiputiloihin.", "intervention": "Low-level laser therapy", "added_in": "expansion_06", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LYMPH-IRELAND-2022", "document_id": "ireland_lymph_2022", "specialty": "Lymphology", "condition_en": "Lymphoedema: laser use and treatment sequencing", "condition_fi": "Lymfaturvotus: laserin käyttö ja hoitojärjestys", "direction": "may_consider", "strength_as_reported": "Strong recommendation for conventional treatment first", "evidence_certainty_as_reported": "Evidence Grade C (source system; not GRADE)", "scope": "Lymphoedema; evidence discussion primarily concerns breast-cancer-related upper-limb lymphoedema", "summary_en": "Recognizes support for laser use but says conventional treatments such as CDT should be considered first because laser takes time and incurs costs.", "summary_fi": "Tunnistaa tuen laserin käytölle mutta kehottaa harkitsemaan ensin tavanomaisia hoitoja, kuten CDT:tä, ajan ja kustannusten vuoksi.", "locator": "GQ92.1, printed and PDF p. 119", "evidence_anchor": "conventional treatments (e.g. CDT) for lymphoedema", "caveat_en": "Strong grades the treatment-priority recommendation, not a strong claim of superior laser efficacy. The separately cited SIO C grade is not the same grading system. Narrative safety wording is not generalized to all cancer settings.", "caveat_fi": "Vahva suositus koskee hoitojärjestystä, ei laserin vahvaa paremmuusnäyttöä. Erikseen siteerattu SIO:n C-luokka on eri järjestelmä; turvallisuuslausetta ei yleistetä kaikkiin syöpätilanteisiin.", "intervention": "Low-level laser therapy / photobiomodulation", "added_in": "expansion_06", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "LYMPH-DUTCH-2014", "document_id": "dutch_lymph_2014", "specialty": "Lymphology", "condition_en": "Lymphoedema volume reduction", "condition_fi": "Lymfaturvotuksen vähentäminen", "direction": "insufficient_evidence", "strength_as_reported": "Narrative evidence assessment; no separate laser grade", "evidence_certainty_as_reported": "", "scope": "Lymphoedema; cited laser studies largely concern breast-cancer-related arm lymphoedema", "summary_en": "States that evidence for soft lasers reducing lymphoedema is lacking, after describing small and inconsistent trials.", "summary_fi": "Toteaa pehmeän laserin lymfaturvotusta vähentävän näytön puuttuvan ja kuvaa pieniä, ristiriitaisia tutkimuksia.", "locator": "Conservative treatment, printed/PDF pp. 58–59, Overige overwegingen", "evidence_anchor": "Op dit moment ontbreekt bewijs over de effectiviteit van soft lasers", "caveat_en": "Historical 2014 wording. A 2022 upload or 2023/2024 module title does not establish a new PBM recommendation. This is not proof that every newer protocol is ineffective.", "caveat_fi": "Historiallinen sanamuoto vuodelta 2014. Vuoden 2022 lataus tai 2023/2024 moduulin otsikko ei tee kannasta uutta PBM-suositusta; lausuma ei osoita kaikkia myöhempiä protokollia tehottomiksi.", "intervention": "Low level laser / soft lasers", "added_in": "expansion_06", "historical": true, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "historical" }, { "id": "OLP-CHINA-NHC-2022", "document_id": "china_olp_nhc_2022", "specialty": "Oral medicine", "condition_en": "Oral lichen planus", "condition_fi": "Suun punajäkälä", "direction": "may_consider", "strength_as_reported": "May be used; ungraded national-guideline option", "evidence_certainty_as_reported": "", "scope": "OLP treatment; other therapies after the drug-therapy sections", "summary_en": "Explicitly permits low-power laser as another treatment option for oral lichen planus.", "summary_fi": "Sallii matalatehoisen laserin suun punajäkälän hoitovaihtoehtona.", "locator": "Section III(4), Other therapies, printed/PDF p. 10; clinical flow chart p. 14", "evidence_anchor": "弱激光疗法及光动力疗法也可用于口腔扁平苔癣的治疗。", "caveat_en": "Photodynamic therapy is named separately and is not PBM. No laser-specific strength, certainty, wavelength or dose is provided; the first-line corticosteroid recommendations remain distinct.", "caveat_fi": "PDT mainitaan erillisenä hoitona eikä se ole PBM:ää. Laserille ei anneta erillistä suositus- tai varmuusluokkaa, aallonpituutta tai annosta; ensilinjan steroidikannat ovat erillisiä.", "intervention": "Weak/low-power laser therapy (弱激光疗法); separate from PDT", "added_in": "expansion_06", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACUTE-ACP-AAFP-PAIN", "document_id": "acp_aafp_acute_2020", "specialty": "Musculoskeletal", "condition_en": "Acute non-low-back musculoskeletal injury: pain at 1–7 days", "condition_fi": "Akuutti tuki- ja liikuntaelinvamma: kipu 1–7 päivässä, ei alaselkäkipu", "direction": "no_benefit", "strength_as_reported": "No standalone laser recommendation", "evidence_certainty_as_reported": "Low-certainty evidence", "scope": "Adults with acute non-low-back musculoskeletal injuries; pain versus placebo at 1–7 days", "summary_en": "Reports no statistically significant pain reduction at 1–7 days with laser compared with placebo.", "summary_fi": "Laser ei vähentänyt kipua tilastollisesti merkitsevästi lumetta enemmän 1–7 päivän seurannassa.", "locator": "Comparative benefits / Pain at 1 to 7 Days, PDF p. 4", "evidence_anchor": "laser therapy (low-certainty evidence)", "caveat_en": "This is a specified pain outcome, not a blanket recommendation against laser. The guideline separately reports improved overall symptom relief. The named device class is generic laser therapy.", "caveat_fi": "Tämä koskee tiettyä kipumittaria ja seuranta-aikaa, ei yleistä laserin vastaista suositusta. Ohje kuvaa erikseen oireiden helpottumista; laserluokkaa ei eritellä.", "intervention": "Laser therapy; class unspecified in guideline narrative", "added_in": "expansion_06", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" }, { "id": "ACUTE-ACP-AAFP-SYMPTOMS", "document_id": "acp_aafp_acute_2020", "specialty": "Musculoskeletal", "condition_en": "Acute non-low-back musculoskeletal injury: overall symptom relief", "condition_fi": "Akuutti tuki- ja liikuntaelinvamma: oireiden yleinen helpottuminen", "direction": "descriptive_support", "strength_as_reported": "Not selected among recommended interventions; only one outcome improved", "evidence_certainty_as_reported": "Moderate certainty in Symptom Relief; low certainty in recommendation rationale (source inconsistency)", "scope": "Adults with acute non-low-back musculoskeletal injuries; overall symptom relief versus placebo", "summary_en": "Reports improved overall symptom relief with laser, but the panel did not include it among recommended treatments because it required improvement in at least two outcomes.", "summary_fi": "Kuvaa laserilla oireiden yleistä helpottumista, mutta paneeli ei valinnut sitä suositeltuihin hoitoihin: valintaan vaadittiin paranemista vähintään kahdessa tulosmittarissa.", "locator": "Comparative benefits / Symptom Relief, PDF p. 4; recommendation rationale p. 6", "evidence_anchor": "only interventions that improved at least 2 outcomes", "caveat_en": "The source gives conflicting certainty labels for the same symptom-relief outcome. Both labels are retained rather than harmonized. Large odds-ratio estimates are not generalized to pain, function or every PBM device.", "caveat_fi": "Lähteen saman oirehyödyn varmuusluokat ovat ristiriitaiset. Molemmat säilytetään; tulosta ei siirretä kipuun, toimintakykyyn tai kaikkiin PBM-laitteisiin.", "intervention": "Laser therapy; class unspecified in guideline narrative", "added_in": "expansion_06", "historical": false, "checked_on": "2026-10-16", "verification_depth": "full_text", "final_grade_recheck_needed": false, "recommendation_class": "clinical_practice_guideline" } ], "source_issues": [ { "id": "ACOEM-HEEL-MODALITY", "document_id": "acoem_ankle", "statement_ids": [ "HEEL-ACOEM" ], "issue_en": "The LLLT section opening sentence says low-dose radiation (radiotherapy). The LLLT heading, summary table and rationale classify LLLT as no recommendation.", "handling_en": "Retained as no recommendation from the table/heading/rationale; the wording inconsistency is displayed on the row. No radiotherapy recommendation is inferred." }, { "id": "SPANISH-LYMPH-CITATION", "document_id": "spain_lymphedema", "statement_ids": [ "LYMPH-SPAIN" ], "issue_en": "Reference 137 used in the laser discussion is the Belmonte 2012 trial of low-frequency low-intensity electrotherapy (PMID 22172923), not LLLT.", "handling_en": "Classified as mention only. Findings from the mismatched trial are not presented as PBM evidence." }, { "id": "ACR-UNSPECIFIED-LASER", "document_id": "acr_ra_integrative", "statement_ids": [ "RA-ACR-THERMAL-MENTION" ], "issue_en": "Laser therapy is one example in the thermal-modality group, without a verified laser type or PBM-specific recommendation.", "handling_en": "Classified as mention only; the conditional group recommendation is not transferred to LLLT alone." }, { "id": "SIGN-EDITION-DATE", "document_id": "sign_chronicpain", "statement_ids": [ "LBP-SIGN" ], "issue_en": "Retrieved SIGN 136 PDF is dated December 2013; a secondary review describes SIGN as 2019.", "handling_en": "The actual retrieved source is dated 2013 and marked historical; no 2019 edition is invented." }, { "id": "EAPD-MIH-GROUPED-GRADE", "document_id": "eapd_mih", "statement_ids": [ "MIH-EAPD" ], "issue_en": "Table 10 conditionally permits a group including laser with low certainty, while the narrative emphasizes limitations and says no individual intervention can be recommended from the reviewed studies.", "handling_en": "The table is reported with its conditional/low group grading; the more cautious narrative is preserved on the row. No laser-only grade or efficacy estimate is inferred." }, { "id": "PTSL-HTW-INTERPRETATION", "document_id": "ptsl_mucositis_2025", "statement_ids": [ "OM-PTSL-HSCT", "OM-PTSL-HNC-CRT", "OM-PTSL-TREAT", "OM-HTW-LASER-ADOPTION" ], "issue_en": "The PTSL umbrella review characterizes HTW 2022 as supporting PBM implementation. Final HTW Guidance 044 explicitly does not support routine laser-PBM adoption because of cost effectiveness, despite acknowledging clinical benefit.", "handling_en": "Own PTSL recommendations are recorded as such. The HTW entry follows the original four-page guidance, not the review summary. Clinical benefit and adoption economics remain distinct." }, { "id": "OARSI-ORIGINAL-SUPPLEMENTS", "document_id": "oarsi_2019", "statement_ids": [ "OA-OARSI-KNEE-NOCOMORB", "OA-OARSI-KNEE-COMORB", "OA-OARSI-KNEE-WIDESPREAD", "OA-OARSI-HIP-POLY", "OA-OARSI-LASER-ACUP" ], "issue_en": "The main article does not show all intervention ratings. Official Supplementary Tables 5 and 8 distinguish knee subgroups, hip/polyarticular laser therapy and laser acupuncture. Table 5 merges GI/CV columns; laser also appears at Level 3 for frailty.", "handling_en": "The original DOCX table cells, merged columns and vote rubric were read directly. Level 3 (40–59% in favor) is not classified as a positive consensus. No blanket strong-against recommendation is assigned to every knee-OA subgroup." }, { "id": "RNAO-HISTORICAL-COLUMN", "document_id": "rnao_pressure_2016", "statement_ids": [ "PRESSURE-RNAO-2016" ], "issue_en": "The 2024 official comparison reproduces the 2016 recommendation against laser in a historical column; it is not the current 2024 recommendation text.", "handling_en": "The record is dated 2016, marked superseded/historical and verified at official historical-reproduction depth. A 2024 PBM therapeutic direction is not inferred." }, { "id": "JAPAN-NARRATIVE-VS-GRADE", "document_id": "japan_chronicpain_2021", "statement_ids": [ "PDN-JAPAN-2021", "PAIN-JAPAN-PHYSICAL" ], "issue_en": "The PDPN narrative describes temporary adjunctive benefit, while the formal LLLT rating is no recommendation, C/low. The general physical-modalities rating is grouped.", "handling_en": "Formal direction follows no recommendation; possible narrative benefit and group scope remain visible. Agreement percentages are not treatment response rates." }, { "id": "EUROGUIDERM-LIGHT-MODALITIES", "document_id": "euroguiderm_acne_2025", "statement_ids": [ "ACNE-EUROGUIDERM-COMEDONAL", "ACNE-EUROGUIDERM-MILD", "ACNE-EUROGUIDERM-SEVERE", "ACNE-EUROGUIDERM-MAINTENANCE" ], "issue_en": "The 2025 long version and 2026 short publication describe one update. Low-strength blue-light recommendations coexist with open red-light/other-light categories. Some recommendation tables are graphical.", "handling_en": "Official tables on printed pp. 27, 32–33 were visually checked. Blue-light, IPL, PDT and ablative-laser positions are not transferred to red/NIR PBM; edition and journal year are separated." }, { "id": "ALBERTA-HOST-FILENAME-YEAR", "document_id": "alberta_lbp_2011", "statement_ids": [ "LBP-ALBERTA-2011-ACUTE", "LBP-ALBERTA-2011-CHRONIC" ], "issue_en": "The CFPC-hosted file is named Oct19 but internally identifies the 2011 second edition of the Alberta TOP guideline.", "handling_en": "Dated 2011 and marked superseded, with TOP as issuing body. The separately retrieved third edition is dated 2015 with minor revision 2017." }, { "id": "STM-HEADING-VS-RATIONALE", "document_id": "stm_oa_2019", "statement_ids": [ "OA-STM-2019" ], "issue_en": "The PBMT heading says limitedly recommended; its rationale also cites a meta-analysis not supporting effectiveness and requests better trials.", "handling_en": "Qualitative conditional support follows the heading, with the conflicting rationale explicitly retained; no numeric strength or certainty grade is invented." }, { "id": "ACP2020-SYMPTOM-CERTAINTY", "document_id": "acp_aafp_acute_2020", "statement_ids": [ "ACUTE-ACP-AAFP-PAIN", "ACUTE-ACP-AAFP-SYMPTOMS" ], "issue_en": "Symptom Relief calls laser evidence moderate certainty; the recommendation rationale on PDF p. 6 calls laser symptom-relief evidence low certainty. Pain at 1–7 days is separately low certainty and not statistically improved.", "handling_en": "Outcome rows are separated. Both conflicting symptom-relief labels are retained; the panel’s two-outcome threshold explains why laser is not among selected recommendations. No blanket strong-against recommendation is invented." }, { "id": "IRELAND-LASER-PRIORITY-GRADE", "document_id": "ireland_lymph_2022", "statement_ids": [ "LYMPH-IRELAND-2022" ], "issue_en": "GQ92.1 has own Evidence Grade C / Strong, but the recommendation prioritizes conventional treatments due to time and cost. The preceding paragraph separately cites SIO C-grade laser support.", "handling_en": "Strong is tied to conventional-treatment priority, not strong laser superiority. Own evidence grade and the external SIO strength label are not conflated." }, { "id": "GERMAN-KNEE-NICE-ADOPTION", "document_id": "german_knee_2024", "statement_ids": [ "OA-GERMANY-2024" ], "issue_en": "Recommendation 39 adopts NICE NG226 1.3.9. Its table displays selected GRADE outcomes for NMES/ultrasound rather than a verified laser-only certainty grade.", "handling_en": "Record the strong grouped recommendation against and 89% panel consensus, leave laser-specific certainty blank, and identify the adopted recommendation lineage." }, { "id": "CDC-GROUP-VS-LASER-GRADE", "document_id": "cdc_opioid_2022", "statement_ids": [ "LBP-CDC-2022" ], "issue_en": "Recommendation 2 Category A / evidence type 2 applies to broad nonopioid management. LLLT is a named implementation option for low-back pain, not an individually graded intervention.", "handling_en": "Retain the named positive option, with no separate LLLT grade and no transfer of the broad recommendation grade to PBM efficacy." } ], "source_checks": [ { "statement_id": "OM-MASCC-HSCT", "document_id": "mascc_mucositis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Photobiomodulation section; Table 1, PBM row 1", "source_anchor": "A recommendation for the prevention of OM with intraoral PBM therapy in patients who undergo HSCT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "c88a4b9a60390798e949a3c738cf410841666833186017a6dab526af5e71bb8c" }, { "statement_id": "OM-MASCC-RT", "document_id": "mascc_mucositis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Photobiomodulation section; Table 1, PBM row 2", "source_anchor": "A recommendation for the prevention of OM with intraoral PBM therapy in patients with cancer who receive H&N RT (without CT)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "c88a4b9a60390798e949a3c738cf410841666833186017a6dab526af5e71bb8c" }, { "statement_id": "OM-MASCC-CRT", "document_id": "mascc_mucositis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Photobiomodulation section; Table 1, PBM row 3", "source_anchor": "A recommendation for the prevention of OM with intraoral PBM therapy in patients with cancer who receive H&N RT with CT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "c88a4b9a60390798e949a3c738cf410841666833186017a6dab526af5e71bb8c" }, { "statement_id": "OM-POGO-HSCT", "document_id": "pogo_mucositis", "verification_depth": "Official recommendation summary", "checked_on": "2026-10-16", "locator": "Official COG endorsed-guideline compilation, PDF p. 43, recommendation 4", "source_anchor": "Use intraoral photobiomodulation therapy in the red light spectrum", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "38d661afbbb79702a7a37ecd2cc516d1aa8873ee156b5bf976d6b9b73fbb5092" }, { "statement_id": "OM-POGO-RT", "document_id": "pogo_mucositis", "verification_depth": "Official recommendation summary", "checked_on": "2026-10-16", "locator": "Official COG endorsed-guideline compilation, PDF p. 43, recommendation 4", "source_anchor": "Use intraoral photobiomodulation therapy in the red light spectrum", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "38d661afbbb79702a7a37ecd2cc516d1aa8873ee156b5bf976d6b9b73fbb5092" }, { "statement_id": "OM-NICE", "document_id": "nice_mucositis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Recommendation 1.1", "source_anchor": "Evidence on efficacy is adequate in quality and quantity", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "40efbd086efad29677fa41d642f5f0ca0f31486d85bcc2cbc82d2fa9ad422d97" }, { "statement_id": "OM-ESMO-HSCT", "document_id": "esmo_mucositis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2, recommendation 3", "source_anchor": "be used to *prevent* oral mucositis in patients receiving HSCT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "2bc4eb628a5e44c55781a3d59c60c3884f80a12e4ab0e9161b1cae0721151140" }, { "statement_id": "OM-ESMO-RT", "document_id": "esmo_mucositis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 3, suggestion 3", "source_anchor": "low-level laser therapy (wavelength ∼632.8 nm)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "2bc4eb628a5e44c55781a3d59c60c3884f80a12e4ab0e9161b1cae0721151140" }, { "statement_id": "RD-MASCC-PREVENT", "document_id": "mascc_dermatitis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 4, prevention recommendations, Laser therapy", "source_anchor": "photobiomodulation or", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "5bd46d35ad992d8d0b28b7e3ac671b1ab77a1f1044512aefef939829cad7ef69" }, { "statement_id": "RD-MASCC-TREAT", "document_id": "mascc_dermatitis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2, PDF p. 9, Laser therapy", "source_anchor": "Photobiomodulation therapy or low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "5bd46d35ad992d8d0b28b7e3ac671b1ab77a1f1044512aefef939829cad7ef69" }, { "statement_id": "XERO-ASCO", "document_id": "asco_xerostomia", "verification_depth": "Official recommendation summary", "checked_on": "2026-10-15", "locator": "Recommendation 1.7; official summary PDF pp. 2–3", "source_anchor": "Evidence remains insufficient for a recommendation for or against", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a7215088d6e7efdf2cc870acddf89a59d70960217eb7dcd9fd19f4640f6b5d34" }, { "statement_id": "ORN-ASCO", "document_id": "asco_orn", "verification_depth": "Abstract", "checked_on": "2026-10-15", "locator": "Abstract, Recommendations", "source_anchor": "No recommendation was possible", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "07c57d1d11e9912ce3344b68223fe7d9a9791a28dd56e1f9ece9369afabbf6f0" }, { "statement_id": "CTS-APTA-2026", "document_id": "apta_cts_2026", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 3 and 33; 2026 Recommendation", "source_anchor": "Clinicians may use either LLLT or HILT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9e423337d2795a342e5adf57e56320505beebd4a13167c23914e59d5f6286ff5" }, { "statement_id": "CTS-AAOS-2024", "document_id": "aaos_cts_2024", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 10 and 35, Non-operative treatments: long-term", "source_anchor": "do not improve long-term patient reported outcomes", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f57fa89933b76f4b4bc8a0dc384681e7f1ae7cb59f3b1427795250f68c454ee8" }, { "statement_id": "CTS-AAOS-2016", "document_id": "aaos_cts_2016", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 11, Laser therapy", "source_anchor": "laser therapy might be effective compared to placebo", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "091d778b643bde95c3604b060b650491644ff2e3c1922f873b79ca84fdf359b7" }, { "statement_id": "CTS-APTA-2019", "document_id": "apta_cts_2019", "verification_depth": "Historical wording reproduced in 2026 full text", "checked_on": "2026-10-15", "locator": "Reproduced in APTA 2026, PDF p. 32, 2019 Recommendation", "source_anchor": "Clinicians should not use LLLT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9e423337d2795a342e5adf57e56320505beebd4a13167c23914e59d5f6286ff5" }, { "statement_id": "RC-APTA", "document_id": "apta_rotator", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Recommendation 31; PDF pp. 3 and 32", "source_anchor": "Clinicians may use laser therapy alone", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "6b7687f44904207524ce8381b8e7a02b3c95c9f5c2d1a444689687cb771806be" }, { "statement_id": "DRF-APTA", "document_id": "apta_radius", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 3 and 50; Therapeutic modalities", "source_anchor": "including laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "3331da51a1d5f11d6b022727fca271fd778a9c19b26afaafa7c7775d439ed729" }, { "statement_id": "HEEL-APTA", "document_id": "apta_heel", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Final published PDF p. 2; Interventions – Physical agents – Low-level laser therapy", "source_anchor": "Clinicians should use low-level laser therapy as part of a rehabilitation program", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "93764cbb88e085093e14334d037503359ebd2af4a8cb2ac4586060b908adf848" }, { "statement_id": "ELBOW-APTA", "document_id": "apta_elbow", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 3 and 41; Interventions: Laser", "source_anchor": "Clinicians may use laser therapy for improvements", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "0c93aa63f65123128b8f1f2eeb85ef46e22225fc58d6c739246259e21b2d119a" }, { "statement_id": "KNEE-AAOS", "document_id": "aaos_knee", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 9 and 43; Laser treatment", "source_anchor": "FDA-approved laser treatment may be used", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f8dabf9aa50def98303a249ac1ee9f0f76f6a95cd80823bfe084cc91d4d9ec11" }, { "statement_id": "ANKLE-APTA", "document_id": "apta_ankle", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 3 and 33; Low-level laser therapy", "source_anchor": "Clinicians may use low-level laser therapy to reduce pain", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a7339954ba044b7d4ce8d2403150fe7ee6bf9e21963c52f6ceda85e03fdeb42e" }, { "statement_id": "ACHILLES-APTA", "document_id": "apta_achilles", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary and 2024 Recommendation: Physical agents – LLLT", "source_anchor": "Clinicians should not use low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "ef9c19bb0985d685776520910b8d94c3ca9a6e9c2346439f37edd89b159114aa" }, { "statement_id": "NECK-APTA-CHRONIC", "document_id": "apta_neck", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary of recommendations, PDF p. 2", "source_anchor": "Dry needling, laser, or intermittent mechanical/manual traction", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "64bfc69fbc1a29bb3984aeb310d1af634e8d9d5469d621f22afb702f734623fd" }, { "statement_id": "NECK-APTA-ACUTE", "document_id": "apta_neck", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary of recommendations, PDF p. 3", "source_anchor": "laser, and short-term use of a cervical collar", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "64bfc69fbc1a29bb3984aeb310d1af634e8d9d5469d621f22afb702f734623fd" }, { "statement_id": "LYMPH-APTA", "document_id": "apta_lymphedema", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 1 and Low-level laser therapy section", "source_anchor": "Low-level laser therapy may be considered", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "10c4db9d4376c15db5b51c233318d4d6b5ee39a1efd37027cec9b3a8836cbde3" }, { "statement_id": "LYMPH-ISL-2023", "document_id": "isl_2023", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 12; nonoperative treatment, Low level laser", "source_anchor": "There is some limit", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "01858604e236893376bd3d9a0ee93fcaf0c2c332c981fe07f9f3f729494c4e0f" }, { "statement_id": "LYMPH-ISL-2020", "document_id": "isl_2020", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 11, Low level laser", "source_anchor": "Reports with small numbers", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "43534c359a93b35e0d1c1f02d65409c94db2a9d4c54bebbf8bb3fc3974c95e98" }, { "statement_id": "LBP-ACP", "document_id": "acp_back", "verification_depth": "Abstract", "checked_on": "2026-10-15", "locator": "Abstract, Recommendation 2", "source_anchor": "low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "605c916be84954a98be2cc5edbf5fe8a1de5c057781a1ef916bf86401450686f" }, { "statement_id": "LBP-NASS-PAIN", "document_id": "nass_back", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary and Physical medicine section; laser therapy recommendations", "source_anchor": "the combination of laser therapy (low-level or high level)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e65e18730df65cbc9b1694cdc7fb2cbf1e0059f9df00ff6dac5acb360da3ef83" }, { "statement_id": "LBP-NASS-FUNCTION", "document_id": "nass_back", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary and Physical medicine section", "source_anchor": "There is conflicting evidence that the combination of laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e65e18730df65cbc9b1694cdc7fb2cbf1e0059f9df00ff6dac5acb360da3ef83" }, { "statement_id": "LBP-NASS-ALONE", "document_id": "nass_back", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary and Physical medicine section", "source_anchor": "there is no short-term benefit of laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e65e18730df65cbc9b1694cdc7fb2cbf1e0059f9df00ff6dac5acb360da3ef83" }, { "statement_id": "LBP-NASS-ACUP", "document_id": "nass_back", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary and Physical medicine section", "source_anchor": "Laser acupuncture provides no short-term or medium-term benefit", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e65e18730df65cbc9b1694cdc7fb2cbf1e0059f9df00ff6dac5acb360da3ef83" }, { "statement_id": "LBP-VA", "document_id": "va_back", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Recommendation 17; PDF pp. 24 and 47", "source_anchor": "insufficient evidence to recommend for or against cupping", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "eeac02f9fca3914ae7e6f86655a545307e6085e566415cfb6f7effb2c4813dac" }, { "statement_id": "NECK-OPTIMA-CHRONIC", "document_id": "optima_neck", "verification_depth": "Full article reproduction; bibliographic identity verified", "checked_on": "2026-10-15", "locator": "Recommendation 5", "source_anchor": "For NAD grades I-II >3 months duration", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "c0ef99061d0acfcc00df522e18000fb07a23c8a9eccaa92f16246d27ccdf00d9" }, { "statement_id": "NECK-OPTIMA-GRADEIII", "document_id": "optima_neck", "verification_depth": "Full article reproduction; bibliographic identity verified", "checked_on": "2026-10-15", "locator": "Recommendation 6", "source_anchor": "For NAD grade III ≤3 months duration", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "c0ef99061d0acfcc00df522e18000fb07a23c8a9eccaa92f16246d27ccdf00d9" }, { "statement_id": "SHOULDER-OPTIMA", "document_id": "optima_shoulder", "verification_depth": "Full article reproduction; bibliographic identity verified", "checked_on": "2026-10-15", "locator": "Abstract recommendation c; recommendations for recent and persistent shoulder pain", "source_anchor": "for shoulder pain of any duration, consider low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "d129b9d9ec35934b762c2b4ad65db3db11dd2eb1d32e5ba6349587f14f17023b" }, { "statement_id": "SHOULDER-OPTIMA-ACUP", "document_id": "optima_shoulder", "verification_depth": "Full article reproduction; bibliographic identity verified", "checked_on": "2026-10-15", "locator": "Abstract recommendation d; persistent shoulder pain recommendation", "source_anchor": "laser acupuncture", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "d129b9d9ec35934b762c2b4ad65db3db11dd2eb1d32e5ba6349587f14f17023b" }, { "statement_id": "TMD-JAPAN", "document_id": "jstmj", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Abstract; sections 3.12–3.13; PDF pp. 1 and 6", "source_anchor": "LLLT be a conditional recommendation", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "b0a60e60494a732337965fde1726b80f465b7394ac4475d396943e4cd95068d0" }, { "statement_id": "TMD-BMJ", "document_id": "bmj_tmd", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Abstract / Recommendations; conditional recommendations against", "source_anchor": "low level laser therapy (alone or in combination with other interventions)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "09586bfe94ba4c39ae3197b0a2c08eb73a1424d8415cf88df3a429725bbd44b6" }, { "statement_id": "OA-NICE", "document_id": "nice_oa", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "NG226 recommendation 1.3.9", "source_anchor": "Do not offer any of the following electrotherapy treatments", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35aaa984714cfec3ee8d99b0f5324a99ff9e061879ef9f35ce543080a354688d" }, { "statement_id": "OA-RACGP", "document_id": "racgp_oa", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary recommendations; Other electrotherapy – Knee and/or hip; matching official web chapter", "source_anchor": "We suggest not offering electrotherapy modalities", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "2f22ff1021035f9dba4a4dbddefc4957b1bbf3b221491e6ad22b3f667db037ea" }, { "statement_id": "DFU-IWGDF", "document_id": "iwgdf", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Recommendation 15; PDF p. 20 and rationale", "source_anchor": "Do not use any interventions reported in the field of physical therapies", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "b72efb7c1e46ae607a785674e1fb598c3fb31640ffa359763bd5ad47461c7e62" }, { "statement_id": "PU-WHS", "document_id": "whs_pressure", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Guideline 7b.5 (new), Principle", "source_anchor": "Laser therapy may result in improvement in pressure ulcer healing", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "d3446a84ddcc243f25099d25ebfdb70a7ae4c9b83127a8d8b122aeb3f81d3ada" }, { "statement_id": "TINNITUS-VA", "document_id": "va_tinnitus", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Recommendation 21; PDF pp. 36 and 71–72", "source_anchor": "We suggest against low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "d3bc361ca764460a27808a4d53ea5c37270df008bee1b2d6871d32a14437cfec" }, { "statement_id": "TINNITUS-S3", "document_id": "s3_tinnitus", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 4.1.8.7", "source_anchor": "Low-level laser therapy should not be practiced for chronic tinnitus", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "b0ba5f412b4620ce7b6153881e9a79224d6e5c275e02e6352c486f53a4657370" }, { "statement_id": "AGA-S3", "document_id": "s3_aga", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.6.7; PDF p. 40", "source_anchor": "We suggest using LLLT as ancillary therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "6dcdbb3cf69ae8fdbefd5f9a8d6c78897cbe5dc5b832358da87e800165c40081" }, { "statement_id": "AGA-S3-LONG", "document_id": "s3_aga", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.6.7; PDF p. 40", "source_anchor": "We cannot make a recommendation for or against treatment for more than 6", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "6dcdbb3cf69ae8fdbefd5f9a8d6c78897cbe5dc5b832358da87e800165c40081" }, { "statement_id": "FI-NECK", "document_id": "fi_neck", "verification_depth": "Full guideline + linked evidence summary", "checked_on": "2026-10-15", "locator": "Fysikaaliset hoidot; linked evidence summary nak08828", "source_anchor": "Matalatehoisen laserin vaikuttavuudesta", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f90cd769890c3b8a9f308e50bc8726f416c6cecf90045f57dafe1617b8219f75" }, { "statement_id": "FI-TMD", "document_id": "fi_tmd", "verification_depth": "Full guideline + linked evidence summary", "checked_on": "2026-10-15", "locator": "Fysioterapia; evidence summary nak08036", "source_anchor": "Laserhoito (pienienergiainen, low-level) saattaa lievittää", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "d66b1228a860bde878ee1e027c74b68d56458255c9aa0b34f5f9c6a3c8c36286" }, { "statement_id": "FI-RA", "document_id": "fi_ra", "verification_depth": "Full guideline + linked evidence summary", "checked_on": "2026-10-15", "locator": "Fysikaaliset hoidot; evidence summary nak08409", "source_anchor": "Laserhoito saattaa helpottaa käsiniveloireita", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9111828825fba4da44f92a04209ac7f68c72916e4e22f5cc04632824428500b0" }, { "statement_id": "FI-SHOULDER", "document_id": "fi_shoulder", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Fysikaaliset hoidot", "source_anchor": "Mitään selvää näyttöä näiden hoitomuotojen hyödyllisyydestä ei ole", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "97b8c49b8e0401579e5609f3c3265e9e043009729f5a40e3f1701653a181db9b" }, { "statement_id": "FI-LEGULCER", "document_id": "fi_legulcer", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Muut paikallishoidot / adjunctive treatments", "source_anchor": "pieniannoksisen laserhoidon", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "0cbbc599ff66d567139fd6d6cccde0a187beeba5bd018c0bf66954ddf410bd3e" }, { "statement_id": "AMD-AAO-MENTION", "document_id": "aao_amd", "verification_depth": "Official update note only", "checked_on": "2026-10-15", "locator": "Official update note, December 2025; refers to PPP p. 21", "source_anchor": "multiwavelength photobiomodulation", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "4e49c95ff96e985a75767b7a525dbd224b974efd170203329cc81d210aebd669" }, { "statement_id": "JAAD-NEUROPATHY", "document_id": "jaad_consensus", "verification_depth": "PubMed + author-repository abstracts", "checked_on": "2026-10-15", "locator": "Abstract, Results", "source_anchor": "peripheral neuropathy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35e835beb93c2197a5adde3eadde7bf87b473f52d9cc59318870486118b2b82e" }, { "statement_id": "JAAD-AGA", "document_id": "jaad_consensus", "verification_depth": "PubMed + author-repository abstracts", "checked_on": "2026-10-15", "locator": "Abstract, Results", "source_anchor": "androgenic alopecia", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35e835beb93c2197a5adde3eadde7bf87b473f52d9cc59318870486118b2b82e" }, { "statement_id": "JAAD-WOUNDS", "document_id": "jaad_consensus", "verification_depth": "PubMed + author-repository abstracts", "checked_on": "2026-10-15", "locator": "Abstract, Results", "source_anchor": "wound ulcers due to multiple etiologies", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35e835beb93c2197a5adde3eadde7bf87b473f52d9cc59318870486118b2b82e" }, { "statement_id": "JAAD-PRESSURE", "document_id": "jaad_consensus", "verification_depth": "PubMed + author-repository abstracts", "checked_on": "2026-10-15", "locator": "Abstract, Results", "source_anchor": "decubitus ulcers", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35e835beb93c2197a5adde3eadde7bf87b473f52d9cc59318870486118b2b82e" }, { "statement_id": "JAAD-DFU-PAIN", "document_id": "jaad_consensus", "verification_depth": "PubMed + author-repository abstracts", "checked_on": "2026-10-15", "locator": "Abstract, Results", "source_anchor": "pain attributed to diabetic foot ulcers", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35e835beb93c2197a5adde3eadde7bf87b473f52d9cc59318870486118b2b82e" }, { "statement_id": "JAAD-RADIATION", "document_id": "jaad_consensus", "verification_depth": "PubMed + author-repository abstracts", "checked_on": "2026-10-15", "locator": "Abstract, Results", "source_anchor": "acute radiation dermatitis", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35e835beb93c2197a5adde3eadde7bf87b473f52d9cc59318870486118b2b82e" }, { "statement_id": "CHINA-ACNE", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 6", "source_anchor": "Acne vulgaris", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-REJUVENATION", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 7", "source_anchor": "Skin rejuvenation", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-WOUNDS", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 8", "source_anchor": "Wound healing and ulcers", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-SCARS", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 9", "source_anchor": "Scar", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-AGA", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 10", "source_anchor": "Androgenetic alopecia", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-AA", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 10", "source_anchor": "Alopecia areata", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-SCARRING", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 10", "source_anchor": "Frontal fibrosing alopecia", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-VIRAL", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 11", "source_anchor": "Viral skin infections", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-CANCER", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 12", "source_anchor": "Conditions secondary to cancer therapies", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "CHINA-OTHER", "document_id": "china_dermatology", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2 and Question 13", "source_anchor": "Melasma, psoriasis", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d43cc6a6a4fd2ff6ad87792f3651a618d3928217aa23c60dae2614e1893782c" }, { "statement_id": "WALT22-OM", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.1.1; Table 1", "source_anchor": "WALT recommendation 2022: clinical practice guidelines", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-XERO", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.2.1", "source_anchor": "Xerostomia and hyposalivation", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-DYSPHAGIA", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.3.1", "source_anchor": "Acute dysphagia", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-DERMATITIS", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.4.1", "source_anchor": "Acute radiation dermatitis", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-LYMPH", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.5.1", "source_anchor": "Lymphedema", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-TASTE", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.6.1", "source_anchor": "Dysgeusia", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-TRISMUS", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.7.1", "source_anchor": "Trismus", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-BONE", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.8.1", "source_anchor": "Bone necrosis", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-VOICE", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.9.1", "source_anchor": "Voice and speech alterations", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-HFS", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.10.1", "source_anchor": "Palmar-Plantar", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-GVHD", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.11.1", "source_anchor": "Graft-versus-Host", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-CIPN", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.12.1", "source_anchor": "peripheral neuropathy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-FIBROSIS", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.13.1", "source_anchor": "radiation-induced fibrosis", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT22-ALOPECIA", "document_id": "walt_2022", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 3.3.14.1", "source_anchor": "chemotherapy-induced alopecia", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5e491054cdb5b9d76df5b103f9b30c092b804b166e9a5deab10e7ed750c4088" }, { "statement_id": "WALT26-BMS", "document_id": "walt_orofacial", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 4.3.1; Table 4", "source_anchor": "WALT Recommendation: Clinical Practice Guidelines", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "882a61a5cfd383da6de19a87effd87e1926420d1846099e159d1ea9e5b1dba2c" }, { "statement_id": "WALT26-TN", "document_id": "walt_orofacial", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 4.3.2; Table 6", "source_anchor": "idiopathic TN", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "882a61a5cfd383da6de19a87effd87e1926420d1846099e159d1ea9e5b1dba2c" }, { "statement_id": "WALT26-PHN", "document_id": "walt_orofacial", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 4.3.3; Table 8", "source_anchor": "Post-Herpetic Neuralgia", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "882a61a5cfd383da6de19a87effd87e1926420d1846099e159d1ea9e5b1dba2c" }, { "statement_id": "WALT26-PTTN", "document_id": "walt_orofacial", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 4.3.4", "source_anchor": "Post-Traumatic Trigeminal", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "882a61a5cfd383da6de19a87effd87e1926420d1846099e159d1ea9e5b1dba2c" }, { "statement_id": "WALT26-GPN", "document_id": "walt_orofacial", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 4.3.5", "source_anchor": "Glossopharyngeal", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "882a61a5cfd383da6de19a87effd87e1926420d1846099e159d1ea9e5b1dba2c" }, { "statement_id": "WALT26-ON", "document_id": "walt_orofacial", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 4.3.5", "source_anchor": "Occipital", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "882a61a5cfd383da6de19a87effd87e1926420d1846099e159d1ea9e5b1dba2c" }, { "statement_id": "RD-MASCC-HNC-PREVENT", "document_id": "mascc_dermatitis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 1, PDF p. 6, Laser therapy", "source_anchor": "Photobiomodulation or low-level laser therapy for head and neck cancer", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "5bd46d35ad992d8d0b28b7e3ac671b1ab77a1f1044512aefef939829cad7ef69" }, { "statement_id": "LYMPH-SIO-ASCO", "document_id": "sio_asco_breast", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Lymphedema recommendation", "source_anchor": "Low-level laser therapy, manual lymphatic drainage, and compression bandaging can be considered", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "fc047ee649f416db40b747f9b2a4b1f83b72aa93f0384931bbf07a59ac7c04f1" }, { "statement_id": "OM-CHINA-PEDIATRIC", "document_id": "china_om_consensus", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Photobiotherapy prevention section", "source_anchor": "For pediatric patients undergoing HSCT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "84577fc50fa108ae644ff4e5ef036e8da430602b6cf3a420f361ac7fc2194c3c" }, { "statement_id": "OM-CHINA-HNC", "document_id": "china_om_consensus", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Photobiotherapy prevention section", "source_anchor": "LLLT has also been proposed to have a role in preventing OM", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "84577fc50fa108ae644ff4e5ef036e8da430602b6cf3a420f361ac7fc2194c3c" }, { "statement_id": "PFP-APTA", "document_id": "apta_pfp", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 3 and 42; Interventions – Biophysical agents", "source_anchor": "Clinicians should not use biophysical agents", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e8ff4fc986fe8e0df40ff79549b0d9c55cdc1c020f1255ddb110c46680d09e8c" }, { "statement_id": "NECK-KNGF", "document_id": "kngf_neck", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Published article PDF pp. 6–7; treatment recommendations", "source_anchor": "It is not recommended that clinicians use dry needling, low-level laser", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "bb83787a0fcd0f594e1a23244d8a35d0272b79f902b4f1dae648f6ea55c3a424" }, { "statement_id": "RA-KNGF", "document_id": "kngf_ra", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 17, C.4; explanatory note 21, PDF p. 36", "source_anchor": "laagvermogen lasertherapie", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a3e269b074cad70c48ba099a015f91deffba7ffa2da6cfc1cbcc725ec10a5c5d" }, { "statement_id": "OA-KNGF", "document_id": "kngf_oa", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Explanatory note 26; PDF pp. 49–50", "source_anchor": "Bied geen behandeling met low level laser therapie", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "ca79025f1550a4e5b47c2e32a0914dccbbcd28ca5e5fe43b7837671c6256b58e" }, { "statement_id": "NECK-DEGAM", "document_id": "german_neck", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Recommendation 29; printed p. 42", "source_anchor": "Lasertherapie sollte zur Behandlung nicht-spezifischer", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a2b36259c5e254b43d99c6d7c6dfc29a39fc8a61410f36d207ab85765cf29f8c" }, { "statement_id": "LBP-GERMAN-NVL", "document_id": "german_back", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Recommendation 5-14; PDF p. 45 / printed p. 44", "source_anchor": "Lasertherapie soll zur Behandlung nicht-spezifischer", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "32c1479a774fd05e3e30866d63011ecc8688236764508bf4ff325f87d7f25e3a" }, { "statement_id": "S3-SUPPORT-CHEMO-PREV", "document_id": "german_supportive", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "7.6; PDF p. 197", "source_anchor": "Für die Anwendung von photobiomodulierender Therapie zur Prophylaxe", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9ef4e50318e78d29e1f12432ba5dba2aedad55c21c6441c7b89a89869107659a" }, { "statement_id": "S3-SUPPORT-HSCT-PREV", "document_id": "german_supportive", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "7.11; PDF p. 211", "source_anchor": "Die Photobiomodulierende Therapie kann zur Prophylaxe", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9ef4e50318e78d29e1f12432ba5dba2aedad55c21c6441c7b89a89869107659a" }, { "statement_id": "S3-SUPPORT-CHEMO-TREAT", "document_id": "german_supportive", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "7.17; PDF p. 221", "source_anchor": "zur Therapie von oraler Mukositis bei Chemotherapie", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9ef4e50318e78d29e1f12432ba5dba2aedad55c21c6441c7b89a89869107659a" }, { "statement_id": "S3-SUPPORT-HSCT-TREAT", "document_id": "german_supportive", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "7.22; PDF p. 227", "source_anchor": "zur Therapie von oraler Mukositis bei Patient*innen mit HSZT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9ef4e50318e78d29e1f12432ba5dba2aedad55c21c6441c7b89a89869107659a" }, { "statement_id": "S3-SUPPORT-RD-PREV", "document_id": "german_supportive", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "11.59; PDF p. 480", "source_anchor": "kann zur Prophylaxe der Radiodermatitis angewendet werden", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9ef4e50318e78d29e1f12432ba5dba2aedad55c21c6441c7b89a89869107659a" }, { "statement_id": "S3-SUPPORT-RAD-ULCER", "document_id": "german_supportive", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "11.73; PDF p. 491", "source_anchor": "Zur Therapie radiogener Hautulzera", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9ef4e50318e78d29e1f12432ba5dba2aedad55c21c6441c7b89a89869107659a" }, { "statement_id": "S3-SUPPORT-RT-OM-PREV", "document_id": "german_supportive", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "11.93; PDF p. 509", "source_anchor": "Eine Prophylaxe der radiogenen oralen Mukositis", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9ef4e50318e78d29e1f12432ba5dba2aedad55c21c6441c7b89a89869107659a" }, { "statement_id": "WOUND-S3-GERMAN", "document_id": "german_wounds", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 9.3.2 Phototherapie; printed p. 179", "source_anchor": "Wegen unsicherer Evidenzgrundlage wurde keine Empfehlung verabschiedet", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "43e41b56d492177f36215cdf4e5815e8bb8c3c49a2a88e0df418a6e447f501eb" }, { "statement_id": "LBP-AUSTRIA", "document_id": "austria_back", "verification_depth": "Complete issued guideline short version", "checked_on": "2026-10-15", "locator": "PDF p. 12, chronic column, footnote 15; table visually verified", "source_anchor": "Lasertherapie", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "569b6b63e39f2858af7e5623e551845d8c06d81ad6b20b5e4141c0323aa0c8b3" }, { "statement_id": "LBP-SIGN", "document_id": "sign_chronicpain", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Section 7, PDF p. 34 / printed p. 28", "source_anchor": "Low level laser therapy should be considered", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "5b7d3f9869f7fcd64574f8c586e3e2fd7af71df5c34c9ad381bceafa77005090" }, { "statement_id": "SHOULDER-DUTCH", "document_id": "dutch_shoulder", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Other interventions, Level 3 evidence conclusion", "source_anchor": "Laser treatment (of all types) appears to be more effective", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "38dbef27ccce7dde30bba6a7f4b9dbb0739e63e2121b4cea9ef2d1b8bae907b8" }, { "statement_id": "ANKLE-DUTCH", "document_id": "dutch_ankle", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Other therapies; evidence statement and unchanged recommendation", "source_anchor": "they are not advised in the treatment of acute LAS", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "c9c9d80f75725521e59ed941accf6e08786c59175c645796c58eeb4aa892cd2c" }, { "statement_id": "NECK-CHIRO-MULTIMODAL", "document_id": "chiro_neck", "verification_depth": "Full article reproduction; bibliographic identity verified", "checked_on": "2026-10-15", "locator": "Recommendations: manipulation / multimodal chronic neck pain", "source_anchor": "low-level laser therapy, soft", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "6f7d93178056d4f2435c77ac62070f45e28d7283c1c56df298f1557f8fe13c1a" }, { "statement_id": "AGA-JAPAN", "document_id": "japan_aga", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "CQ5; PDF pp. 8–9", "source_anchor": "Irradiation by light-emitting diodes (LED) and low-level lasers is recommended.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "2366973787998d157357cf25e8c8669423721b28a63fcfe22f9717c18c38ba92" }, { "statement_id": "AGA-SPAIN-ADJUNCT", "document_id": "spain_aga", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Procedures in the management of androgenetic alopecia", "source_anchor": "low-level laser therapy were considered to have proven but variable efficacy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1b8466857a767fb1e26dc25a9d91c09c9d93275f36b70e8585d3b862cc4fd5d2" }, { "statement_id": "AGA-SPAIN-ADOLESCENT", "document_id": "spain_aga", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 7; Pediatric/Adolescent patients", "source_anchor": "Adjuvant treatments such as platelet-rich plasma therapy or low-level laser therapy can be considered in adolescent patients", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1b8466857a767fb1e26dc25a9d91c09c9d93275f36b70e8585d3b862cc4fd5d2" }, { "statement_id": "AGA-SPAIN-PREGNANCY", "document_id": "spain_aga", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 7; Pregnancy", "source_anchor": "Low-level laser therapy and PRP therapy may be considered if clinically necessary", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1b8466857a767fb1e26dc25a9d91c09c9d93275f36b70e8585d3b862cc4fd5d2" }, { "statement_id": "FIBRO-CHINA", "document_id": "china_fibromyalgia", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 1 and §3.2.4.3", "source_anchor": "We suggest low‐level laser therapy to patients with fibromyalgia over no interventions", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "3bb341d89249ee9ffcbf87d64346838c1f7d3d04e44cc87828637a26a44c1d17" }, { "statement_id": "LBP-ACOEM", "document_id": "acoem_back", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Low-level Laser Therapy for Treatment of Low Back Pain", "source_anchor": "Low-level laser therapy is not recommended for treatment of low back pain.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "fb86cbb97e5dc44cd056f6826cd2dcb3016f325727d4c8d47137f2b33597796a" }, { "statement_id": "NECK-ACOEM", "document_id": "acoem_cervical", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Low-Level Laser Therapy; PDF p. 84", "source_anchor": "There is no recommendation for or against the use of low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "c1ad062f3f7ac78ac79fe0d896fbbdb819721337a15071cb1e8bcebbbd87dbf0" }, { "statement_id": "RC-ACOEM", "document_id": "acoem_shoulder", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 114", "source_anchor": "Low-level laser therapy is not recommended for treatment of rotator cuff tendinopathies.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "076c0280fdc296c56232b2809e93e0ed72142a2282fec4bce2a196c289e05b17" }, { "statement_id": "BICEPS-ACOEM", "document_id": "acoem_shoulder", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 216", "source_anchor": "Low-level laser therapy is not recommended for the treatment of bicipital tendinopathies.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "076c0280fdc296c56232b2809e93e0ed72142a2282fec4bce2a196c289e05b17" }, { "statement_id": "MYOFASCIAL-ACOEM", "document_id": "acoem_shoulder", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 662", "source_anchor": "There is no recommendation for or against the use of low-level laser therapy for the treatment of trigger points/myofascial pain.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "076c0280fdc296c56232b2809e93e0ed72142a2282fec4bce2a196c289e05b17" }, { "statement_id": "ELBOW-ACOEM", "document_id": "acoem_elbow", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 114", "source_anchor": "Low-level laser therapy is moderately not recommended for the treatment of acute, subacute, or chronic lateral or medial epicondylalgia.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f0ba62b30ee99522bd3048b9d8dcc99f729a3b6aea24714b3ba6ca3c1ef57434" }, { "statement_id": "PRONATOR-ACOEM", "document_id": "acoem_elbow", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 144", "source_anchor": "Low-level laser therapy is not recommended for acute, subacute, or chronic pronator syndrome.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f0ba62b30ee99522bd3048b9d8dcc99f729a3b6aea24714b3ba6ca3c1ef57434" }, { "statement_id": "RADIAL-ACOEM", "document_id": "acoem_elbow", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 155", "source_anchor": "Low-level laser therapy is not recommended for acute, subacute, or chronic radial nerve entrapment", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f0ba62b30ee99522bd3048b9d8dcc99f729a3b6aea24714b3ba6ca3c1ef57434" }, { "statement_id": "ULNAR-ACOEM", "document_id": "acoem_elbow", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 173–174", "source_anchor": "Low-level laser therapy is not recommended for the treatment of acute, subacute, or chronic ulnar neuropathies.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f0ba62b30ee99522bd3048b9d8dcc99f729a3b6aea24714b3ba6ca3c1ef57434" }, { "statement_id": "CTS-ACOEM", "document_id": "acoem_hand", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 99", "source_anchor": "Low level laser therapy is not recommended for treatment of acute, subacute, or chronic CTS.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35eff79dd95bbcb5670dfae78b3281389821a3bec8909bde3027c6c59678fe7e" }, { "statement_id": "HAND-OA-ACOEM", "document_id": "acoem_hand", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 324", "source_anchor": "Low-level laser therapy is moderately not recommended for treatment of hand osteoarthrosis.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "35eff79dd95bbcb5670dfae78b3281389821a3bec8909bde3027c6c59678fe7e" }, { "statement_id": "KNEE-PAIN-ACOEM", "document_id": "acoem_knee", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary table PDF p. 9; body p. 91", "source_anchor": "The use of low-level laser therapy is not recommended for treatment of osteoarthrosis and acute, subacute, or chronic knee pain.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5d02be307f15250a35e205c52d5ad70b4da3caa4d866b859736b151bdd94a01" }, { "statement_id": "KNEE-OA-ACOEM", "document_id": "acoem_knee", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary table PDF p. 9; body p. 91", "source_anchor": "The use of low-level laser therapy is not recommended for treatment of osteoarthrosis and acute, subacute, or chronic knee pain.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5d02be307f15250a35e205c52d5ad70b4da3caa4d866b859736b151bdd94a01" }, { "statement_id": "MENISCUS-ACOEM", "document_id": "acoem_knee", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary table PDF p. 9; LLLT recommendation p. 146", "source_anchor": "Low-level Laser Therapy for Meniscal tears", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5d02be307f15250a35e205c52d5ad70b4da3caa4d866b859736b151bdd94a01" }, { "statement_id": "KNEE-LIGAMENT-ACOEM", "document_id": "acoem_knee", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 133, 139–140", "source_anchor": "iontophoresis, low-level laser therapy, phonophoresis", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f5d02be307f15250a35e205c52d5ad70b4da3caa4d866b859736b151bdd94a01" }, { "statement_id": "ACHILLES-ACOEM-CHRONIC", "document_id": "acoem_ankle", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 68", "source_anchor": "Low-level laser therapy is recommended for treatment of select patients with chronic Achilles tendinopathy.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e2554f675f7d3e303050c932d0000ba5f67c801c02ac4bf61f0fc59f3b0ef966" }, { "statement_id": "ACHILLES-ACOEM-OTHER", "document_id": "acoem_ankle", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 69", "source_anchor": "There is no recommendation for or against the use of low-level laser therapy for treatment of acute, subacute, or post-operative Achilles tendinopathy.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e2554f675f7d3e303050c932d0000ba5f67c801c02ac4bf61f0fc59f3b0ef966" }, { "statement_id": "ANKLE-ACOEM-ACUTE", "document_id": "acoem_ankle", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 179", "source_anchor": "Low-level laser therapy is not recommended for treatment of acute ankle sprain.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e2554f675f7d3e303050c932d0000ba5f67c801c02ac4bf61f0fc59f3b0ef966" }, { "statement_id": "ANKLE-ACOEM-CHRONIC", "document_id": "acoem_ankle", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 179", "source_anchor": "Low-level laser therapy is not recommended for treatment of subacute or chronic ankle sprain.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e2554f675f7d3e303050c932d0000ba5f67c801c02ac4bf61f0fc59f3b0ef966" }, { "statement_id": "HEEL-ACOEM", "document_id": "acoem_ankle", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Summary table; PDF p. 304, LLLT heading and rationale", "source_anchor": "There are two moderate-quality studies providing conflicting results for the use of LLLT.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "e2554f675f7d3e303050c932d0000ba5f67c801c02ac4bf61f0fc59f3b0ef966" }, { "statement_id": "HIP-ACOEM", "document_id": "acoem_hip", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 144", "source_anchor": "There is no recommendation for or against the use of low-level laser therapy for treatment of osteoarthrosis or acute, subacute, or chronic hip pain.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "50ae264cb295b4ecbad7b82548471ac34f8fd2ae6bf98158a82dcbdda81269d5" }, { "statement_id": "CRPS-ACOEM", "document_id": "acoem_chronicpain", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 151", "source_anchor": "There is no recommendation regarding low-level laser therapy (LLLT) for treatment of complex regional pain syndrome", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "61ffcbe8e21e3536598b5e52ac611706510f2f125e4db4732cb95c7bb9c633b1" }, { "statement_id": "FIBRO-ACOEM", "document_id": "acoem_chronicpain", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF pp. 290–291", "source_anchor": "Low-level laser therapy is not recommended for fibromyalgia.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "61ffcbe8e21e3536598b5e52ac611706510f2f125e4db4732cb95c7bb9c633b1" }, { "statement_id": "NEUROPATHIC-ACOEM", "document_id": "acoem_chronicpain", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 379", "source_anchor": "Low-level laser therapy is not recommended for treatment of neuropathic pain.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "61ffcbe8e21e3536598b5e52ac611706510f2f125e4db4732cb95c7bb9c633b1" }, { "statement_id": "RA-OTTAWA", "document_id": "ottawa_ra", "verification_depth": "Abstract", "checked_on": "2026-10-15", "locator": "Abstract; conclusion", "source_anchor": "Ottawa Panel recommends the use of low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "fbfc0a0817e9f2e809b7f8c7631d70a0bd186a39c673181fe88723f84b19bd93" }, { "statement_id": "RA-SPAIN", "document_id": "spain_ra", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Printed p. 109; physical therapies", "source_anchor": "El láser de baja potencia parece conseguir una disminución", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "943dc456ea53dbcac9cb84eadaa3e0bcfcb53fc4b7a63e36771122166d58a921" }, { "statement_id": "LYMPH-SPAIN", "document_id": "spain_lymphedema", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Printed pp. 88–89; references p. 95", "source_anchor": "se precisan más estudios para precisar mejor su efectividad", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "95dedf927edcaff623e9b5fbb62edbb3f3858c00458a4ae4fcf50d8b396b6c08" }, { "statement_id": "TMD-KOREA", "document_id": "korean_tmd", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "§3.7.1; R15; Meridian LLLT meta-analysis", "source_anchor": "physical therapy in Korean medicine should be considered to improve symptoms", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "68a1a69c9a09bd1ecf2e171c57e61cd6cec26f326874817e0617fb764bbc6bfe" }, { "statement_id": "ORAL-IRAE-MASCC", "document_id": "mascc_immunotherapy", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Oral lichen planus / lichenoid reactions; Box 1", "source_anchor": "photobiomodulation (PBM) may help with pain management at the acute phase", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "5db43930492babb63fa4c7efcfa816421e5781968e46acd3fd49459995510579" }, { "statement_id": "ORAL-GVHD-MASCC", "document_id": "mascc_gvhd", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Oral mucosal manifestations; topical interventions", "source_anchor": "More research is needed about these interventions.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "554d2c17ccf407208f0b667f13c97a36606fbce294ca200fc7534fe83377384f" }, { "statement_id": "OM-NCCN-HISTORICAL", "document_id": "nccn_mucositis", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Low-Level Laser Therapy section", "source_anchor": "A preventive role for LLLT has been investigated in 2 settings", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "8e8ac7f19d1764620efe65f8a2db15a0d8f9dec7abef084a28cc22579d0a6136" }, { "statement_id": "PRESSURE-NPUAP-2014", "document_id": "npuap_pressure_2014", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "PDF p. 214 / printed p. 212; Laser recommendation 1", "source_anchor": "laser therapy is not recommended for routine use at this time", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "57daadff77594acacb952751e99b23764f19631327793fba49f9ccaf1141a2a6" }, { "statement_id": "VOICE-HEALTHY-CONSENSUS", "document_id": "vocal_consensus", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2, statements on healthy voice and items 11–13", "source_anchor": "I use PBM with voice professionals to reduce symptoms of vocal fatigue.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "671c0fe70cde74e2b8056507f914147b1aee914991e12c20c1aa64f436b62dd2" }, { "statement_id": "VOICE-BEHAVIORAL-CONSENSUS", "document_id": "vocal_consensus", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2, item 16", "source_anchor": "I use PBM in cases of patients with behavioral dysphonia without laryngeal injury.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "671c0fe70cde74e2b8056507f914147b1aee914991e12c20c1aa64f436b62dd2" }, { "statement_id": "VOICE-TENSION-NOCONSENSUS", "document_id": "vocal_consensus", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2, item 14", "source_anchor": "I use PBM in cases of patients with dysphonia due to muscle tension.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "671c0fe70cde74e2b8056507f914147b1aee914991e12c20c1aa64f436b62dd2" }, { "statement_id": "VOICE-ORGANIC-NOCONSENSUS", "document_id": "vocal_consensus", "verification_depth": "Full text", "checked_on": "2026-10-15", "locator": "Table 2, items 17–20", "source_anchor": "I use PBM in cases of patients with dysphonia of neurological origin.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "671c0fe70cde74e2b8056507f914147b1aee914991e12c20c1aa64f436b62dd2" }, { "statement_id": "RA-ACR-THERMAL-MENTION", "document_id": "acr_ra_integrative", "verification_depth": "Authorized licensed guideline summary", "checked_on": "2026-10-15", "locator": "Intervention definitions: Thermal modalities; Recommendations", "source_anchor": "paraffin therapy, and laser therapy.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "5a62593c9cfda99af40c6fa0d177708e5b154c037d123dd95863b78542a69c9f" }, { "statement_id": "FIBRO-TSPMR", "document_id": "turkish_fibro", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 4 / printed p. 114, Physical therapy modalities and Low-level laser therapy", "source_anchor": "its use in FM is still controversial", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "6e97e73eb94ddcd4e4ca8d1b72dd8b773ef090de5cc0a6d533f7c978eccc6f4d" }, { "statement_id": "OM-AAPD", "document_id": "aapd_lasers", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 3 / printed p. 143, Background", "source_anchor": "PBM therapy has been used in children", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "57a19934a5eb2d69387736004f9c656bb88e921a2fcae69dfc7b621ce74c3946" }, { "statement_id": "PAIN-AAPD", "document_id": "aapd_lasers", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 3 / printed p. 143, Background", "source_anchor": "may reduce postsurgical or traumatic oral pain", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "57a19934a5eb2d69387736004f9c656bb88e921a2fcae69dfc7b621ce74c3946" }, { "statement_id": "ULCERS-AAPD", "document_id": "aapd_lasers", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 3 / printed p. 143, Background", "source_anchor": "more studies are needed to establish the laser type and therapeutic parameters", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "57a19934a5eb2d69387736004f9c656bb88e921a2fcae69dfc7b621ce74c3946" }, { "statement_id": "OM-AFSOS-2015", "document_id": "afsos_mucites", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Slide / PDF p. 13, Point sur les autres moyens de prévention", "source_anchor": "cette planche constitue une synthèse à titre d’information", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "ee5d5a0d2433185fcde89ab25ee818b15f2942e916300e27bac48de544ba882e" }, { "statement_id": "OM-AFSOS-RT-2020", "document_id": "afsos_oral_rt", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 10, During radiotherapy / Mucites", "source_anchor": "Autre thérapeutique possible", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "93f72724e3e9fb182b7711a22a871fb19ca62a693190532657ab3a7f38b16a99" }, { "statement_id": "TASTE-AFSOS", "document_id": "afsos_taste", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 19, mouth-care recommendations", "source_anchor": "peut limiter les troubles du goût", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "942a348716d6b1ff536c324f95f26dfb9c77c6cf4cac61f9a26416b831234356" }, { "statement_id": "RD-AFSOS-CETUXIMAB", "document_id": "afsos_skin", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 12", "source_anchor": "le laser de basse énergie est en cours d’évaluation", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "336cc1e7ea23817a0f7d488e546c11d3e181310a67afb829d1307a0555574c05" }, { "statement_id": "RD-AFSOS-ESTABLISHED", "document_id": "afsos_skin", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF pp. 16–17", "source_anchor": "Le laser basse énergie est en cours d’évaluation.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "336cc1e7ea23817a0f7d488e546c11d3e181310a67afb829d1307a0555574c05" }, { "statement_id": "RD-ESTRO-PREVENT", "document_id": "estro_rd", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Table 5; General recommendations / Prevention", "source_anchor": "Photo-biomodulation or low-level laser therapy may be used to prevent higher grades of RID", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "68a3a11f1e0db517c42a432d1502c75fa08898621d19c3ce335fbaa09b87c968" }, { "statement_id": "WOUND-FDI", "document_id": "fdi_lasers", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Context paragraph", "source_anchor": "improvement of wound healing during photobiomodulation", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "69797abf8f843c84d818b05c4ee465100dcbdc4edb98b33ee3286c5a54ea505a" }, { "statement_id": "AMD-DOG-2025", "document_id": "dog_amd", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 2, conclusion", "source_anchor": "Die Behandlung sollte aktuell nur im Rahmen klinischer Studien durchgeführt werden.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1251e9f36e9bb0947be36910d4a4a4a788b4a86361937ac9eb4ebb27fd42fc98" }, { "statement_id": "RD-SCOR-2020", "document_id": "scor_rd", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "§5.5.2; PDF p. 23 / printed p. 21", "source_anchor": "these guidelines do not recommend the use of PBMT at this time", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "85cc21416fee3d5a5af0c987ee594179d5bc21d2643aa3a70038752a0155f32f" }, { "statement_id": "RD-MEXICO-2022", "document_id": "mexico_rd", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Treatment / emerging approaches, before Conclusions", "source_anchor": "further research is needed on long-term effects", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "99aa90095916578c81d777c2ad0d70974401e847d7ecfc1b75e2af23d1b6ce8e" }, { "statement_id": "MIH-EAPD", "document_id": "eapd_mih", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Table 10; PDF p. 14; narrative p. 13", "source_anchor": "ozone/laser can be used to reduce the symptoms of hypersensitivity", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a2ac4777e99d8d979f68f515f14f5e90efb74725a217d7cccccdb89c0de9d428" }, { "statement_id": "EB-ORAL-LESIONS", "document_id": "eb_oral", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "§3.1.7 Oral bullae and ulcerations", "source_anchor": "cord blood platelet gel (CBPG) and low‐level laser therapy (LLLT)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "eca11fa97716b283aa7c32d27b0bfc3e90be3aa7783edb3913675e7d6c02d519" }, { "statement_id": "APHTHAE-S2K", "document_id": "s2k_aphthae", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Printed pp. 18–19; treatment pathway and commentary", "source_anchor": "ist eine therapeutische", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "ee584525e98ab2cdfa4ef2361df1e5675ffa7c57aac351ee9c18ac344304830f" }, { "statement_id": "RAS-INDIA", "document_id": "ras_india", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Treatment narrative, paragraph on lasers", "source_anchor": "diode laser (low-level laser treatment mode)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "cb83b34e4a1414b0853b3b96cb4e2aa0f5d523c7ae988f873c5668f281a372d4" }, { "statement_id": "TINNITUS-AAOHNS-2026", "document_id": "aao_tinnitus_2026", "verification_depth": "Official update note only", "checked_on": "2026-10-16", "locator": "Research agenda item 27 (KAS 14); official page dated 9 October 2026", "source_anchor": "low‐level laser therapy, and bimodal stimulation", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1ec17143d15e6621638b606790ba4dee2f505c1d933959535dd2c72933d89dd1" }, { "statement_id": "DENTINE-MEA", "document_id": "dentine_mea", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Table 2, in-office treatment / laser row", "source_anchor": "diode laser (high and low power)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "2267696276904334982235936d978bdcf1e6a5b2802e7b4fa4317b25c88feb85" }, { "statement_id": "DENTINE-ISP", "document_id": "isp_dentine", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Occlusive approach by laser / Laser parameter settings", "source_anchor": "There is lack of evidence to suggest a gold standard for laser parameter settings", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "04adc372e14d618d15c0df74182f140a2caa35d33e0c552656f970ab0c4d646b" }, { "statement_id": "VAGINAL-SENORIF", "document_id": "senorif_breast", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Table 27; PDF pp. 161–162", "source_anchor": "photobiomodulation, lipofilling", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "c568f81f21e00d827155c7e2cfda60dee48af3e951f0a7530f7563d213c7e37a" }, { "statement_id": "OM-POGO-RT-NONCARCINOMA", "document_id": "pogo_mucositis", "verification_depth": "Official recommendation summary", "checked_on": "2026-10-16", "locator": "COG official endorsed-guideline summary, PDF p. 44, recommendation 5", "source_anchor": "radiotherapy for head and neck cancers other than carcinoma", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "38d661afbbb79702a7a37ecd2cc516d1aa8873ee156b5bf976d6b9b73fbb5092" }, { "statement_id": "OA-OARSI-KNEE-NOCOMORB", "document_id": "oarsi_2019", "verification_depth": "Full guideline + original official supplements", "checked_on": "2026-10-16", "locator": "Official Supplementary Table 5; Level 4B / No Comorbidities", "source_anchor": "Level 4B", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a69cf49d84f7972fc13b73f78e307fd95761f49ba80c2e6a253427d9f5f59aec" }, { "statement_id": "OA-OARSI-KNEE-COMORB", "document_id": "oarsi_2019", "verification_depth": "Full guideline + original official supplements", "checked_on": "2026-10-16", "locator": "Official Supplementary Table 5; Level 3; GI/CV merged column and Frailty column", "source_anchor": "Level 3- 40%-59%", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a69cf49d84f7972fc13b73f78e307fd95761f49ba80c2e6a253427d9f5f59aec" }, { "statement_id": "OA-OARSI-KNEE-WIDESPREAD", "document_id": "oarsi_2019", "verification_depth": "Full guideline + original official supplements", "checked_on": "2026-10-16", "locator": "Official Supplementary Table 5; Level 4A / Widespread pain–Depression", "source_anchor": "Level 4A-", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a69cf49d84f7972fc13b73f78e307fd95761f49ba80c2e6a253427d9f5f59aec" }, { "statement_id": "OA-OARSI-HIP-POLY", "document_id": "oarsi_2019", "verification_depth": "Full guideline + original official supplements", "checked_on": "2026-10-16", "locator": "Official Supplementary Table 8; Laser Therapy row", "source_anchor": "Treatments that were Strongly Recommended Against", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a69cf49d84f7972fc13b73f78e307fd95761f49ba80c2e6a253427d9f5f59aec" }, { "statement_id": "OA-OARSI-LASER-ACUP", "document_id": "oarsi_2019", "verification_depth": "Full guideline + original official supplements", "checked_on": "2026-10-16", "locator": "Official Supplementary Table 8; Laser Acupuncture row", "source_anchor": "Laser Acupuncture", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a69cf49d84f7972fc13b73f78e307fd95761f49ba80c2e6a253427d9f5f59aec" }, { "statement_id": "DFU-AUSTRALIA-2021", "document_id": "australia_wound_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Recommendation 12; Clinical question and Summary justification", "source_anchor": "We suggest not using agents reported to have an effect on wound healing", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a904a77acc45dd4edf79a8edf5fdfdd40db2c703b6a2d5e304c51a04d6057c3d" }, { "statement_id": "MRONJ-CHINA-2024", "document_id": "china_mronj_2024", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "§2.5.2.5 Ozone and low-level laser therapy", "source_anchor": "there still lacks high quality study evaluating the therapeutic effects of LLLT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "56cfbc5bfd737f462a916f7e48bd25580183d69fb63d1da4dd762861500286f3" }, { "statement_id": "MRONJ-ITALY-PALLIATIVE", "document_id": "italy_mronj_2023", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Table 7(c), nonsurgical protocol and footnote c", "source_anchor": "biostimulation with ozone or low- level laser", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "7234f1480d20e70bc190aa738830813191fa8990bb71bfde9660ed64cf9f8747" }, { "statement_id": "OA-ARGENTINA-KNEE", "document_id": "argentina_oa_2010", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 35 / printed p. 34, Physical modalities summary", "source_anchor": "Laserterapia, Magnetoterapia y Electroestimulación no mejoran estos parámetros", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "feb344ae64756e61afe74b76a91e2500e144518bebedad9cd048b4b4e3f837a0" }, { "statement_id": "OA-ARGENTINA-HAND", "document_id": "argentina_oa_2010", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 35 / printed p. 34, OA de manos", "source_anchor": "Ultrasonido y Laserterapia no han demostrado beneficios", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "feb344ae64756e61afe74b76a91e2500e144518bebedad9cd048b4b4e3f837a0" }, { "statement_id": "OA-IMSS-LASER", "document_id": "imss_knee_2014", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Printed pp. 29–30, LASER", "source_anchor": "Las Guías Australianas recomiendan", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "6570d578edeb9137631e46051a0db538aff33127fcf1927f3ea9161bc2f18203" }, { "statement_id": "OM-AAPD-CHEMO-HCT", "document_id": "aapd_chemo_2022", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 5 / printed p. 575, Oral mucositis", "source_anchor": "prevent OM in patients undergoing HCT conditioning", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1c7c7e8b94f75dc4f7136b79b67a303fe8e415fa128212c8eb701c6ad998d0e2" }, { "statement_id": "OM-AAPD-CHEMO-RT", "document_id": "aapd_chemo_2022", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 5 / printed p. 575, Oral mucositis", "source_anchor": "patients undergoing radiation treatment for head and neck cancer", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1c7c7e8b94f75dc4f7136b79b67a303fe8e415fa128212c8eb701c6ad998d0e2" }, { "statement_id": "OM-AAPD-CHEMO-TREAT", "document_id": "aapd_chemo_2022", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 5 / printed p. 575", "source_anchor": "PBM can decrease pain and the duration and severity", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1c7c7e8b94f75dc4f7136b79b67a303fe8e415fa128212c8eb701c6ad998d0e2" }, { "statement_id": "CMP-SOUTHAFRICA", "document_id": "southafrica_cmp_2023", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Consensus findings before Table 5", "source_anchor": "Low-level laser therapy (LLLT) was the only non-pharmacological intervention", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "653b38c3f24344a2e00d50724d2d9721bc6ab59c92e76ae73984dab83a9f905b" }, { "statement_id": "OA-SINGAPORE-2026", "document_id": "singapore_knee_2026", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "After Recommendation 6; Notepad: Other complementary and alternative treatments", "source_anchor": "laser therapy may be less effective than conventional therapies like exercise", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "eb85ef24e9bd319c87a021829b2a1c5f276114110117c52cbf67d9cd8b28a44c" }, { "statement_id": "LYMPH-FRAMEWORK-2006", "document_id": "lympho_framework_2006", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 55 / printed p. 51, Laser therapy", "source_anchor": "Low level laser therapy has shown potential", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "9d2dfd64dfc0b492c94d26e613cef3a7045b933c200b5f07a67e0aa4e248ae87" }, { "statement_id": "OM-PTSL-HSCT", "document_id": "ptsl_mucositis_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Clinical implications / Key clinical recommendations", "source_anchor": "PBMT should be incorporated as standard supportive care", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "4b94c666a7adb98ede37a4c12b03ad41413e3dcb15c4e464cbc8ebee93544099" }, { "statement_id": "OM-PTSL-HNC-CRT", "document_id": "ptsl_mucositis_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Key clinical recommendations", "source_anchor": "head and neck chemoradiation", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "4b94c666a7adb98ede37a4c12b03ad41413e3dcb15c4e464cbc8ebee93544099" }, { "statement_id": "OM-PTSL-TREAT", "document_id": "ptsl_mucositis_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Key clinical recommendations", "source_anchor": "Therapeutic PBMT", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "4b94c666a7adb98ede37a4c12b03ad41413e3dcb15c4e464cbc8ebee93544099" }, { "statement_id": "OM-PTSL-PEDS-PROTOCOL", "document_id": "ptsl_mucositis_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Clinical implications; Table 9", "source_anchor": "patients who cannot tolerate intraoral application", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "4b94c666a7adb98ede37a4c12b03ad41413e3dcb15c4e464cbc8ebee93544099" }, { "statement_id": "OM-HTW-LASER-ADOPTION", "document_id": "htw_mucositis_2022", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Final Guidance 044, PDF pp. 1–3", "source_anchor": "routine adoption of laser photobiomodulation cannot be supported", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1bfef05c595e9aa72a78450f508c6e321a923b2a55ca93a3129ed4df6b3d964c" }, { "statement_id": "OM-HTW-LED", "document_id": "htw_mucositis_2022", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Final Guidance 044, PDF pp. 1–3", "source_anchor": "Further research is recommended to establish the clinical effectiveness of LED", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "1bfef05c595e9aa72a78450f508c6e321a923b2a55ca93a3129ed4df6b3d964c" }, { "statement_id": "LIP-RUSSIA-WOUND", "document_id": "russia_lip_2024", "verification_depth": "Full guideline reproduction; edition and identity checked", "checked_on": "2026-10-16", "locator": "Rehabilitation, stage I after surgery; reference 72", "source_anchor": "С целью улучшения заживления послеоперационной раны", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "397c921dc6c9827f0752ec0a483eaf091c699bf3f4372f2a36db6d1dac229d80" }, { "statement_id": "LIP-RUSSIA-TRISMUS", "document_id": "russia_lip_2024", "verification_depth": "Full guideline reproduction; edition and identity checked", "checked_on": "2026-10-16", "locator": "Rehabilitation after surgery / stage III; reference 79", "source_anchor": "на область жевательной мускулатуры и височно-нижнечелюстной сустав", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "397c921dc6c9827f0752ec0a483eaf091c699bf3f4372f2a36db6d1dac229d80" }, { "statement_id": "LIP-RUSSIA-RD-PREV", "document_id": "russia_lip_2024", "verification_depth": "Full guideline reproduction; edition and identity checked", "checked_on": "2026-10-16", "locator": "Rehabilitation during RT; reference 99", "source_anchor": "профилактики развития радиоиндуцированного дерматита более 2 степени", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "397c921dc6c9827f0752ec0a483eaf091c699bf3f4372f2a36db6d1dac229d80" }, { "statement_id": "LIP-RUSSIA-OM-PREV", "document_id": "russia_lip_2024", "verification_depth": "Full guideline reproduction; edition and identity checked", "checked_on": "2026-10-16", "locator": "Rehabilitation during RT; reference 100", "source_anchor": "на полость рта для профилактики мукозита полости рта", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "397c921dc6c9827f0752ec0a483eaf091c699bf3f4372f2a36db6d1dac229d80" }, { "statement_id": "LIP-RUSSIA-DYSPHAGIA", "document_id": "russia_lip_2024", "verification_depth": "Full guideline reproduction; edition and identity checked", "checked_on": "2026-10-16", "locator": "Rehabilitation during RT; reference 101", "source_anchor": "для профилактики острой дисфагии", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "397c921dc6c9827f0752ec0a483eaf091c699bf3f4372f2a36db6d1dac229d80" }, { "statement_id": "OA-RACGP-2009", "document_id": "racgp_oa_2009", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Recommendation 18; PDF pp. 19 and 34 / printed pp. 17 and 32", "source_anchor": "weak evidence to support GPs recommending low level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "dd319c76c48b3b78643c7b663da119f4bda41899392e30602896d17511cb567b" }, { "statement_id": "LBP-ECUADOR-2016", "document_id": "ecuador_lbp_2016", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "PDF p. 28 / printed p. 26, Electroterapia", "source_anchor": "quedando a criterio del especialista", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f75f2801bfd3f95c64e86a857c8c3db36d16a8f046d8c4616202d23c26604a2f" }, { "statement_id": "PRESSURE-RNAO-2016", "document_id": "rnao_pressure_2016", "verification_depth": "Historical 2016 recommendation in official 2024 comparison", "checked_on": "2026-10-16", "locator": "2016 recommendation 3.6 reproduced in official 2024 comparison, PDF p. 14", "source_anchor": "laser therapy (not recommended)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "a5b2a99fadf3fa77e035f172870e3da7be7aee502d2bc33f7eb4b247c568062a" }, { "statement_id": "OA-STM-2019", "document_id": "stm_oa_2019", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Treatment / PBMT or low-level laser therapy (LLLT)", "source_anchor": "PBMT or low-level laser therapy (LLLT) (limitedly recommended)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f2bcbad40e35272e343cdabcfb639292a26f5290409483f7ad499e641783635c" }, { "statement_id": "RD-EVIQ-PREVENT", "document_id": "eviq_rd_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Management / prevention / Photo-biomodulation (low-level laser) therapy", "source_anchor": "as an emerging strategy to prevent higher-grade RID", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "360bec58b059becd3105a649266e9971745afd7e764b4992608d6274581047df" }, { "statement_id": "PDN-AAN-2011", "document_id": "aan_pdn_2011", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Nonpharmacologic treatment / Recommendations, item 2", "source_anchor": "low-intensity laser treatment, and Reiki therapy should probably not be considered", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "4e8716b81fb64fc53338c77c52211fab6bf47754c720f9e9d603a2176f45e0a1" }, { "statement_id": "AGA-EGYPT-2025", "document_id": "egypt_aga_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Table 1, statement 17 / Key Area 4: Low-Level Laser Therapy", "source_anchor": "Low-level laser therapy three times per week causes a decrease in the number of vellus hairs", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "d49fbfb53e405828d6edbbca45469f6c281094ae0ca4886af382beadd163fb0c" }, { "statement_id": "AGA-CANADA-2025", "document_id": "canada_aga_2025", "verification_depth": "Abstract", "checked_on": "2026-10-16", "locator": "Primary indexed abstract / recommended with near consensus", "source_anchor": "Five interventions are recommended with near consensus", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "96817120522e0f60700ba0cb8ba65373e1ee9f7ee5dd6c7f76edbf4bdf43afa4" }, { "statement_id": "VULVODYNIA-EUROPE-2021", "document_id": "iusti_vulval_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Vulvodynia / physical therapies; PDF page 14", "source_anchor": "low-level laser therapy and radiofrequency for treating vulvodynia", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "b557e662e0aff0261f2ae397e384d8e6d17fb433df5b182cf49ba828c2e3bfb7" }, { "statement_id": "ACNE-EUROGUIDERM-COMEDONAL", "document_id": "euroguiderm_acne_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Section 6.1.1 graphical table, printed p. 27 / PDF p. 33; rationale p. 31", "source_anchor": "no clear recommendations could be drawn", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "ccb8fcacd77c8711882a816567464d35ca0c349f1e91dbec3bc6a3ae24b38cda" }, { "statement_id": "ACNE-EUROGUIDERM-MILD", "document_id": "euroguiderm_acne_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "6.2.1 graphical table, printed p. 32 / PDF p. 38; rationale printed pp. 35–38", "source_anchor": "insufficient evidence to recommend the treatment of papulopustular acne with", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "ccb8fcacd77c8711882a816567464d35ca0c349f1e91dbec3bc6a3ae24b38cda" }, { "statement_id": "ACNE-EUROGUIDERM-SEVERE", "document_id": "euroguiderm_acne_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "6.2.2 graphical table, printed p. 33 / PDF p. 39; rationale printed pp. 35–38", "source_anchor": "insufficient evidence to recommend the treatment of papulopustular acne with", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "ccb8fcacd77c8711882a816567464d35ca0c349f1e91dbec3bc6a3ae24b38cda" }, { "statement_id": "ACNE-EUROGUIDERM-MAINTENANCE", "document_id": "euroguiderm_acne_2025", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Section 7.1, printed p. 66 / PDF p. 72", "source_anchor": "maintenance treatment with red light, blue light, IPL, Laser, PDT or oral zinc", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "ccb8fcacd77c8711882a816567464d35ca0c349f1e91dbec3bc6a3ae24b38cda" }, { "statement_id": "PAIN-JAPAN-PHYSICAL", "document_id": "japan_chronicpain_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "CQ G-3, printed pp. 134–135 / PDF pp. 136–137", "source_anchor": "推奨度：推奨なし［合意率89.5％］", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "176b24c54f3740d03a25840500be3ce9d8339eccb3e42e1a2aa26f68d7e53050" }, { "statement_id": "NECK-JAPAN-KATAKORI", "document_id": "japan_chronicpain_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "CQ L-5, printed p. 191 / PDF p. 193", "source_anchor": "物理療法（低出力レーザー）", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "176b24c54f3740d03a25840500be3ce9d8339eccb3e42e1a2aa26f68d7e53050" }, { "statement_id": "TN-JAPAN-2021", "document_id": "japan_chronicpain_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "CQ M-2-4, printed p. 201 / PDF p. 203, item 2a", "source_anchor": "推奨度：推奨なし ［合意率85.0％］", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "176b24c54f3740d03a25840500be3ce9d8339eccb3e42e1a2aa26f68d7e53050" }, { "statement_id": "BMS-JAPAN-2021", "document_id": "japan_chronicpain_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "CQ M-3-4, printed pp. 205–206 / PDF pp. 207–208, item 2", "source_anchor": "エビデンス総体の統括：D（非常に低い）", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "176b24c54f3740d03a25840500be3ce9d8339eccb3e42e1a2aa26f68d7e53050" }, { "statement_id": "PIDAP-JAPAN-2021", "document_id": "japan_chronicpain_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "CQ M-4-4, printed p. 209 / PDF p. 211", "source_anchor": "PIDAP に特定した治療効果の研究は未だ報告がない", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "176b24c54f3740d03a25840500be3ce9d8339eccb3e42e1a2aa26f68d7e53050" }, { "statement_id": "PDN-JAPAN-2021", "document_id": "japan_chronicpain_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "CQ P-6-3, printed pp. 256–257 / PDF pp. 258–259", "source_anchor": "PDPN の痛みに対する補助的鎮痛法として有用である", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "176b24c54f3740d03a25840500be3ce9d8339eccb3e42e1a2aa26f68d7e53050" }, { "statement_id": "LBP-ALBERTA-2011-ACUTE", "document_id": "alberta_lbp_2011", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Additional options / insufficient-evidence list, PDF and printed p. 14", "source_anchor": "low-level laser therapy*", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "647a1fe6eee55f5b74dd3ad385f2a51e15e659dc56fd83464c65d42f0f726d06" }, { "statement_id": "LBP-ALBERTA-2011-CHRONIC", "document_id": "alberta_lbp_2011", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Additional options / insufficient-evidence list, PDF and printed p. 21", "source_anchor": "low-level laser therapy*", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "647a1fe6eee55f5b74dd3ad385f2a51e15e659dc56fd83464c65d42f0f726d06" }, { "statement_id": "LBP-ALBERTA-2015-ACUTE", "document_id": "alberta_lbp_2015", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Additional options / insufficient-evidence list, PDF and printed p. 11", "source_anchor": "Low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "42b17fd749f21557b20bf021aa94a32d8a2c53b6561030febe5d6944949831f8" }, { "statement_id": "LBP-ALBERTA-2015-CHRONIC", "document_id": "alberta_lbp_2015", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Additional options / insufficient-evidence list, PDF and printed p. 20", "source_anchor": "Low-level laser therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "42b17fd749f21557b20bf021aa94a32d8a2c53b6561030febe5d6944949831f8" }, { "statement_id": "ACHILLES-DUTCH-2021", "document_id": "dutch_achilles_2021", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Module 4 / Submodule 4.3: non-surgical treatment options / Recommendations", "source_anchor": "laser therapy and light therapy", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "84156bbbd1cba41d3b5b6840816a09b524954b17860b456a8683b7a8f2be8aad" }, { "statement_id": "OA-GERMANY-2024", "document_id": "german_knee_2024", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Recommendation 39, printed p. 22 and pp. 155–158", "source_anchor": "Lasertherapie", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "eb85fe27dbb2f4b091e821e2bc8fe1d320dc27bf64f373364fa3abd1714dc328" }, { "statement_id": "FIBRO-GERMANY-2017", "document_id": "german_fibro_2017", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Physical modalities / Lasertherapie, printed and PDF p. 78", "source_anchor": "Lasertherapie sollte nicht empfohlen werden.", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "0ae380ea1b822d0cdedf5753560c14c344c1493f8926b552ebcd54bfea5dbfef" }, { "statement_id": "LBP-CDC-2022", "document_id": "cdc_opioid_2022", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Recommendation 2 / Implementation Considerations / condition-specific nonpharmacologic approaches", "source_anchor": "psychological therapy, spinal manipulation, low-level laser therapy, massage", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "0f3416f0cf9f4056f00d429dda02af53db767d1bd6b3cb40cdee88967cec7ad0" }, { "statement_id": "LYMPH-IRELAND-2022", "document_id": "ireland_lymph_2022", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "GQ92.1, printed and PDF p. 119", "source_anchor": "conventional treatments (e.g. CDT) for lymphoedema", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "922b053064543a2871867abd4d97d2da32f45a3544929029fc079d54b6aa01e6" }, { "statement_id": "LYMPH-DUTCH-2014", "document_id": "dutch_lymph_2014", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Conservative treatment, printed/PDF pp. 58–59, Overige overwegingen", "source_anchor": "Op dit moment ontbreekt bewijs over de effectiviteit van soft lasers", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "f9c586b651502fbccec604c1d17b24f67c9402a6105507477fff678419e0a707" }, { "statement_id": "OLP-CHINA-NHC-2022", "document_id": "china_olp_nhc_2022", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Section III(4), Other therapies, printed/PDF p. 10; clinical flow chart p. 14", "source_anchor": "弱激光疗法及光动力疗法也可用于口腔扁平苔癣的治疗。", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "347884e165b006ac93be801619bdfacd2e94fd0f068033e30bf630ba244d70e7" }, { "statement_id": "ACUTE-ACP-AAFP-PAIN", "document_id": "acp_aafp_acute_2020", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Comparative benefits / Pain at 1 to 7 Days, PDF p. 4", "source_anchor": "laser therapy (low-certainty evidence)", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "d0eb3f22d36b5c4499eedefcf61e11270a3ad381fbca3d0c9be6d72a28c782df" }, { "statement_id": "ACUTE-ACP-AAFP-SYMPTOMS", "document_id": "acp_aafp_acute_2020", "verification_depth": "Full text", "checked_on": "2026-10-16", "locator": "Comparative benefits / Symptom Relief, PDF p. 4; recommendation rationale p. 6", "source_anchor": "only interventions that improved at least 2 outcomes", "anchor_found_in_retrieved_text": true, "source_snapshot_sha256": "d0eb3f22d36b5c4499eedefcf61e11270a3ad381fbca3d0c9be6d72a28c782df" } ] }